Targeting Neuro Immuno Vascular Interactions In The Brain And The Periphery
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Targeting Neuro Immuno Vascular Interactions In The Brain And The Periphery
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Author : Imola Wilhelm
language : en
Publisher: Frontiers Media SA
Release Date : 2023-02-13
Targeting Neuro Immuno Vascular Interactions In The Brain And The Periphery written by Imola Wilhelm and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-02-13 with Science categories.
Immune Response To Cerebral Ischemia Exploring Mechanisms And Potential Treatment Targets
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Author : Xiaoxing Xiong
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-10
Immune Response To Cerebral Ischemia Exploring Mechanisms And Potential Treatment Targets written by Xiaoxing Xiong and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-10 with Medical categories.
Recent Advances In Psychiatry From Psycho Neuro Immunology Research Autoimmunencephalitis Autoimmune Encephalopathy Mild Encephalitis
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Author : Karl Bechter
language : en
Publisher: Frontiers Media SA
Release Date : 2019-08-12
Recent Advances In Psychiatry From Psycho Neuro Immunology Research Autoimmunencephalitis Autoimmune Encephalopathy Mild Encephalitis written by Karl Bechter and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-12 with categories.
Growing evidence derived from cerebrospinal fluid (CSF), neuropathological, imaging, genetic, and epidemiological studies link neuroinflammation and immune dysregulation to a subset of individuals with a variety of severe mental disorders (SMDs), including affective and non-affective psychotic disorders. Further, the recent discoveries of neuronal surface antibodies (NSAs) in autoimmune encephalitis (AE) presenting with diverse neuropsychiatric disorders such as psychosis and cognitive decline, among many others, provides further support to the notion that CNS autoimmunity and neuroinflammation can contribute to the neurobiology of psychiatric disturbances. Further, these immune mechanisms may contribute to a subset of patients currently diagnosed as having treatment-resistant SMDs such as schizophrenia and major depressive disorder. Additionally, mounting data indicate that various infections can serve as an immunological trigger of aberrant immune responses, presumably by causing release of excess neural antigen, thereby giving rise to NSAs or aberrant immune cellular responses to give rise to primary or secondary psychiatric disorders such as schizophrenia and those associated with AE, respectively. Collectively, these findings support the “mild encephalitis” hypothesis of SMD. The significant overlap among AE-associated psychosis, systemic autoimmune disorder-associated psychosis, and psychotic disorders associated with pathological processes involving inflammation and immune dysregulation has also prompted some authors to adopt the term “autoimmune psychosis” (AP). This term reflects that this psychosis subtype is mechanistically linked to complex neuroimmune and inflammatory signalling abnormalities that can be responsive to early immunomodulatory treatment. It also suggests that a subset of AP might represent an incomplete or “forme fruste” subtype of AE presenting with dominant or pure psychiatric symptoms mimicking primary psychiatric illnesses. Because data indicate that delayed diagnosis and treatment may lead to permanent sequelae, early recognition of AP utilizing neurodiagnostic workup (e.g., CSF analysis, neuroimaging, and EEG) and its early treatment with appropriate immunotherapy are paramount to a meaningful recovery. This eBook will provide an overview of the current knowledge and research areas from epidemiology, risk factors and diagnosis to the management of these conditions, in this rapidly emerging field, helping to bridge the gaps in knowledge that currently exist in the disciplines of Psychiatry, Neurology, and Neuroimmunology.
Recent Advances In Immunology To Target Cancer Inflammation And Infections
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Author : Jagat Kanwar
language : en
Publisher: BoD – Books on Demand
Release Date : 2012-05-09
Recent Advances In Immunology To Target Cancer Inflammation And Infections written by Jagat Kanwar and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-05-09 with Medical categories.
Immunology is the branch of biomedical sciences to study of the immune system physiology both in healthy and diseased states. Some aspects of autoimmunity draws our attention to the fact that it is not always associated with pathology. For instance, autoimmune reactions are highly useful in clearing off the excess, unwanted or aged tissues from the body. Also, generation of autoimmunity occurs after the exposure to the non-self antigen that is structurally similar to the self, aided by the stimulatory molecules like the cytokines. Thus, a narrow margin differentiates immunity from auto-immunity as already discussed. Hence, finding answers for how the physiologic immunity turns to pathologic autoimmunity always remains a question of intense interest. However, this margin could be cut down only if the physiology of the immune system is better understood. The individual chapters included in this book will cover all the possible aspects of immunology and pathologies associated with it. The authors have taken strenuous effort in elaborating the concepts that are lucid and will be of reader's interest.
Peripheral Immunity In Parkinson S Disease Emerging Role And Novel Target For Therapeutics
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Author : Cristoforo Comi
language : en
Publisher: Frontiers Media SA
Release Date : 2019-12-23
Peripheral Immunity In Parkinson S Disease Emerging Role And Novel Target For Therapeutics written by Cristoforo Comi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-23 with categories.
Crosstalk Between Peripheral And Local Immune Response In The Pathophysiology Of Stroke And Neurodegeneration Diseases
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Author : Yuanjian Fang
language : en
Publisher: Frontiers Media SA
Release Date : 2023-12-27
Crosstalk Between Peripheral And Local Immune Response In The Pathophysiology Of Stroke And Neurodegeneration Diseases written by Yuanjian Fang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-27 with Medical categories.
The Molecular Immunology Of Neurological Diseases
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Author : Sunil Kumar
language : en
Publisher: Academic Press
Release Date : 2021-02-16
The Molecular Immunology Of Neurological Diseases written by Sunil Kumar and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-16 with Medical categories.
The Molecular Immunology of Neurological Diseases provides a comprehensive review of current updates in molecular immunogenetics of different neurological diseases. Readers will learn about the role of immune cells and their modulation strategies to help in the development of therapeutic approaches for both acute and chronic neurodegenerative disorders. There is no other book available on the topic. It has long been thought that the brain is an immune-privilege organ with very limited immune response. However recent studies have made clear that both systemic 'brain' and peripheral 'blood' immune cell responses play key roles in determining brain pathology in neurodegenerative disorders. This book summarizes the role of immune cell activation in the central nervous system microenvironment in acute and chronic neurodegenerative disorders. In addition, it discusses the key role of immune cells and their modulation strategies for the development of current therapeutic approaches. Discusses the molecular immunogenetics of different neurological diseases Covers strategies for the development of therapeutic approaches Encompasses both acute and chronic neurogenerative disorders Describes the molecular pathogenesis of viral genes in various diseases Features chapters on migraine, muscular dystrophy and cancer
The Neuroendocrine Immune Network
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Author : S. Freier
language : en
Publisher: CRC Press
Release Date : 2018-01-18
The Neuroendocrine Immune Network written by S. Freier and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-18 with Medical categories.
This informative publication updates the study of interaction of the nervous and endocrine systems with the immune system in the body. It describes the anatomical basis of these interactions, reviewing the innervation of lymphoid tissue and mast cells. The book discusses the effect of the endocrine system on immune function, including the relation of sex to the immune response. Emphasis is given to opioids, substance P, neurotensin, vasoactive intestinal peptide, somatostatin and cholecystokinin. Also addressed is the immunoregulatory effect of leukotrienes and platelet-activating factors. Scrutinized within are stress as an aspect of neuro-immune interactions, and the central role of the hypothalamus in this context. The book reviews the eye and the gastrointestinal tract with respect to the coordination of the nervous, endocrine, and immune systems in serving these organs. This work is of particular value to those in immunology, endocrinology, gastroenterology, and developmental biology.
Neuropathology Of Drug Addictions And Substance Misuse Volume 2
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Author : Victor R Preedy
language : en
Publisher: Academic Press
Release Date : 2016-03-25
Neuropathology Of Drug Addictions And Substance Misuse Volume 2 written by Victor R Preedy and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-03-25 with Medical categories.
Neuropathology of Drug Addictions and Substance Misuse, Volume 2: Stimulants, Club and Dissociative Drugs, Hallucinogens, Steroids, Inhalants and International Aspects is the second of three volumes in this informative series and offers a comprehensive examination of the adverse consequences of the most common drugs of abuse. Each volume serves to update the reader's knowledge on the broader field of addiction as well as to deepen understanding of specific addictive substances. Volume 2 addresses stimulants, club and dissociative drugs, hallucinogens, and inhalants and solvents. Each section provides data on the general, molecular and cellular, and structural and functional neurological aspects of a given substance, with a focus on the adverse consequences of addictions. Research shows that the neuropathological features of one addiction are often applicable to those of others, and understanding these commonalties provides a platform for studying specific addictions in more depth and may ultimately lead researchers toward new modes of understanding, causation, prevention, and treatment. However, marshalling data on the complex relationships between addictions is difficult due to the myriad material and substances. - Offers a modern approach to understanding the pathology of substances of abuse, offering an evidence-based ethos for understanding the neurology of addictions - Fills an existing gap in the literature by serving as a "one-stop-shopping synopsis of everything to do with the neuropathology of drugs of addiction and substance misuse - Includes in each chapter: list of abbreviations, abstract, introduction, applications to other addictions and substance misuse, mini-dictionary of terms, summary points, 6+ figures and tables, and full references - Offers coverage of preclinical, clinical, and population studies, from the cell to whole organs, and from the genome to whole body
Research Awards Index
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Author :
language : en
Publisher:
Release Date : 1989
Research Awards Index written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Medicine categories.