Teratogenicity Testing
DOWNLOAD
AUDIOBOOK
READ ONLINE
Download Teratogenicity Testing PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Teratogenicity Testing book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Teratogenicity Testing
DOWNLOAD
AUDIOBOOK
READ ONLINE
Author : Paul Barrow
language : en
Publisher:
Release Date : 2013
Teratogenicity Testing written by Paul Barrow and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Abnormalities, Human categories.
Teratology is the study of chemical-induced birth defects. This book is a comprehensive guide to the procedures and methods commonly employed in the safety testing of all classes of chemical for teratogenicity (also referred to as embryotoxicity, developmental toxicity or prenatal toxicity). The various international regulatory requirements are explained in detail, in order that the reader may perform all of the necessary studies for the successful registration or marketing authorisation of a new pharmaceutical, industrial chemical, crop protection product or food additive. Written in the highly successful Methods in Molecular Biology series format, each chapter gives clear complete instructions on how to perform the task in hand. The authors are respected experts in their field, all with hands-on experience of the procedures described. Teratogenicity Testing: Methods and Protocols gives crucial guidance and tips on how to deal with unexpected results and overcome regulatory difficulties.
Teratological Testing
DOWNLOAD
AUDIOBOOK
READ ONLINE
Author : T.V.N. Persaud
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Teratological Testing written by T.V.N. Persaud and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
The study of birth defects has assumed an importance even greater now than in the past because mortality rates attributed to congenital anomalies have declined far less than those for other causes of death, such as infectious and nutritional diseases. It is estimated that as many as 50% of all pregnancies terminate as miscarriages. In the majority of cases this is the result of faulty development. Major congenital malformations are found in at least 2% of all liveborn infants, and 22% of all stillbirths and infant deaths are associated with severe congenital anomalies. Teratological studies of an experimental nature are neither ethical nor justifiable in humans. Numerous investigations have been carried out in laboratory animals and other experimental models in order to improve our understanding of abnormal intra-uterine development. In less than two decades the field of experimental teratology has advanced phenomenally. As a result of the wide range of information that is now accumulating, it has become possible to obtain an insight into the causes, mec.;hanisms and prevention of birth defects. However, considerable work will be needed before these problems can be resolved. The· contributions in this volume deal primarily with the areas of terato logical evaluation and the use of selected animal models for the study of con genital anomalies. It is not only a documentation of the latest experimental work, but it also indicates new and important areas for future research.
Teratogenicity Testing
DOWNLOAD
AUDIOBOOK
READ ONLINE
Author : Paul C. Barrow
language : en
Publisher: Humana Press
Release Date : 2012-11-09
Teratogenicity Testing written by Paul C. Barrow and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-09 with Medical categories.
Teratology is the study of chemical-induced birth defects. This book is a comprehensive guide to the procedures and methods commonly employed in the safety testing of all classes of chemical for teratogenicity (also referred to as embryotoxicity, developmental toxicity or prenatal toxicity). The various international regulatory requirements are explained in detail, in order that the reader may perform all of the necessary studies for the successful registration or marketing authorisation of a new pharmaceutical, industrial chemical, crop protection product or food additive. Written in the highly successful Methods in Molecular BiologyTM series format, each chapter gives clear complete instructions on how to perform the task in hand. The authors are respected experts in their field, all with hands-on experience of the procedures described. Teratogenicity Testing: Methods and Protocols gives crucial guidance and tips on how to deal with unexpected results and overcome regulatory difficulties.
Tests Of Teratogenicity In Vitro
DOWNLOAD
AUDIOBOOK
READ ONLINE
Author :
language : en
Publisher:
Release Date : 1975
Tests Of Teratogenicity In Vitro written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1975 with categories.
Basic Mutagenicity Tests
DOWNLOAD
AUDIOBOOK
READ ONLINE
Author : David J. Kirkland
language : en
Publisher: Cambridge University Press
Release Date : 1990-08-31
Basic Mutagenicity Tests written by David J. Kirkland and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990-08-31 with Medical categories.
A summary of the essential texts that must be performed on all new compounds before they can be registered for use in the UK.
Teratogenicity Testing
DOWNLOAD
AUDIOBOOK
READ ONLINE
Author : Luís Félix
language : en
Publisher: Humana
Release Date : 2019-06-27
Teratogenicity Testing written by Luís Félix and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-27 with Medical categories.
This detailed book provides a compilation of laboratory techniques and tests to assess the risks to embryo-fetal development from drug exposure during early developmental stages. After an introduction to teratogenicity testing, the contents explore both in vitro and in vivo techniques in the study of the teratogenic and fetotoxic effects of drugs, as well as numerous animal-based teratology methods. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and comprehensive, Teratogenicity Testing: Methods and Protocols describes methods that integrate a battery of tests that can be performed in cells, organs, tissues, and animal models for evaluating toxicity and/or the safety of compounds in early developmental stages with the goal of estimating, preventing, or minimizing the teratogenic potential of drugs.
The Testing Of Chemicals For Carcinogenicity Mutagenicity And Teratogenicity
DOWNLOAD
AUDIOBOOK
READ ONLINE
Author : Canada. Department of National Health and Welfare
language : en
Publisher:
Release Date : 1975
The Testing Of Chemicals For Carcinogenicity Mutagenicity And Teratogenicity written by Canada. Department of National Health and Welfare and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1975 with Carcinogenicity testing categories.
Principles For The Testing Of Drugs For Teratogenicity
DOWNLOAD
AUDIOBOOK
READ ONLINE
Author : World Health Organization
language : en
Publisher:
Release Date : 1967
Principles For The Testing Of Drugs For Teratogenicity written by World Health Organization and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1967 with categories.
Principles For The Testing Of Drugs For Teratogenicity
DOWNLOAD
AUDIOBOOK
READ ONLINE
Author : World Health Organization
language : en
Publisher:
Release Date : 1967
Principles For The Testing Of Drugs For Teratogenicity written by World Health Organization and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1967 with categories.
Supplementary Mutagenicity Tests
DOWNLOAD
AUDIOBOOK
READ ONLINE
Author : United Kingdom Environmental Mutagen Society. Sub-Committee on Guidelines for Mutagenicity Testing
language : en
Publisher: Cambridge University Press
Release Date : 1993-11-11
Supplementary Mutagenicity Tests written by United Kingdom Environmental Mutagen Society. Sub-Committee on Guidelines for Mutagenicity Testing and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-11-11 with Medical categories.
Originally published in 1993, this volume describes supplementary tests used to assess risks of in vitro mutagenicity when basic safety tests were inconclusive.