Teratogens
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Drugs As Teratogens
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Author : James L. Schardein
language : en
Publisher:
Release Date : 1976
Drugs As Teratogens written by James L. Schardein and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1976 with Chemotherapy categories.
Catalog Of Teratogenic Agents
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Author : Thomas H. Shepard
language : en
Publisher: JHU Press
Release Date : 2004
Catalog Of Teratogenic Agents written by Thomas H. Shepard and has been published by JHU Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Teratogenic agents categories.
Links information on experimental teratogenic agents with the congenital defects in human beings.
Teratogens
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Author : Vera M. Kolb
language : en
Publisher: Elsevier
Release Date : 2013-10-22
Teratogens written by Vera M. Kolb and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Health & Fitness categories.
Teratogens Chemicals Which Cause Birth Defects, 2nd Revised Edition is a collection of papers that discusses the practical aspect of teratogens, particularly regarding information on the teratogenic potential of chemicals. This book describes the principles and mechanism of teratogenesis, including the initiating mechanisms during the subcellular or molecular level and the role of bio-activation in teratogenesis. Investigations have been done on the relationship between spontaneous abortion in women exposed to organic solvents, antineoplastic agents, and chemicals in plastics. Other studies also show that teratogenicity depends in part on enzymatic bio-activation to an embryotoxic reactive intermediate. This text also explains the legal and ethical aspects of fetal protection policies with emphasis on fetal protection. Protection to expecting women extends to pregnant students exposed to teratogenic chemicals in chemistry laboratories. The book explains how and where to get information about the teratogenic potential of chemicals and how to properly handle these chemicals in the laboratory. The book also provides a list from RTECs of toxic chemicals which can cause reproductive effects. This book can prove useful for chemists, pharmacologists, obstetricians, gynecologists, and practitioners of general medicine.
Teratogenic Mechanisms
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Author : T.V.N. Persaud
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Teratogenic Mechanisms written by T.V.N. Persaud and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
The study of birth defects has assumed an importance even greater now than in the past because mortality rates attributed to congenital anomalies have declined far less than those for other causes of death, such as infectious and nutritional diseases. It is estimated that as many as 50% of all pregnancies terminate as miscarriages. In the majority of cases this is the result of faulty development. Major congenital malformations are found in at least 2% of all liveborn infants, and 22% of all stillbirths and infant deaths are associated with severe congenital anomalies. Teratological studies of an experimental nature are neither ethical nor justifiable in humans. Numerous investigations have been carried out in laboratory animals and other experimental models in order to improve our understanding of abnormal intra-uterine development. In less than two decades the field of experimental teratology has advanced phenomenally. As a result of the wide range of information that is now accumulating, it has become possible to obtain an insight into the causes, mechanisms and prevention of birth defects. However, considerable work will be needed before these problems can be resolved. This book brings together some of the more recent and important research findings related to the mechanisms and pathogenesis of abnormal develop ment. It is not only a documentation of the latest experimental work, but it also points out future directions that seem productive and challenging.
Teratogenesis An Inquiry Into The Causes Of Monstrosities History Of The Theories Of The Past
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Author : John William Ballantyne
language : en
Publisher:
Release Date : 1897
Teratogenesis An Inquiry Into The Causes Of Monstrosities History Of The Theories Of The Past written by John William Ballantyne and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1897 with Monsters categories.
Epidemiologic Methods For Detection Of Teratogens
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Author : Marcus A. Klingberg
language : en
Publisher:
Release Date : 1979
Epidemiologic Methods For Detection Of Teratogens written by Marcus A. Klingberg and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979 with Abnormalities, Human categories.
Mechanisms And Pathogenesis
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Author : James Wilson
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09
Mechanisms And Pathogenesis written by James Wilson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Science categories.
Teratology
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Author : C.L. Berry
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Teratology written by C.L. Berry and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
In the fifteen years since the thalidomide disaster teratology has become a science in its own right, distinct from its progenitors, experimental embryology and develop mental biology, but bearing many of the familiar features of both parents. In this growth period there have been contributions from many different scientific disciplines as diverse as molecular biology and obstetrics, which have united in the field of study of congenital malformations. Scientists in academic departments, government research institutes and industrial pharmacology have all explored ways of evaluating the potential of drugs and chem icals to damage the embryo; strict methods of screening for teratogenicity have be come mandatory in most parts of the world. Despite a wealth of basic information in the fields of genetics and embryology, there is little concrete knowledge of the causal mechanisms of malformation in Man, and even less concerning the relevance to Man of those laboratory and animal tests which decide the fate of potentially useful drugs. It is timely, therefore, that in 1975 a group of young and active sci entists and clinicians concerned with the broader implications of teratology should review the past and look to the future of this emerging speciality. In this volume the editors have blended the opinions of teratologists; their message presages change in many of the old and accepted areas of investigative teratology.
Basic Concepts In Teratology
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Author : T. V. N. Persaud
language : en
Publisher: Alan R. Liss
Release Date : 1985
Basic Concepts In Teratology written by T. V. N. Persaud and has been published by Alan R. Liss this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985 with Abnormalities categories.
Teratogenesis And Reproductive Toxicology
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Author : E.M. Johnson
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Teratogenesis And Reproductive Toxicology written by E.M. Johnson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The resolution of links between exposure to components of our complex environmental and causation of reproductive effects in the population constitutes an important problem in the field of toxicology. The focus of this volume is developmental toxicology, which represents one aspect of reproductive toxicology dealing with the study of adverse effects on the developing conceptus. Developmental toxicology, which includes teratogenesis as one of its manifesta tions, provides a fertile field for research in several basic and clinical disciplines; this field also receives input from several disoiplines such as developmental and molecu lar biology, pathology, pharmacology and toxicology, pediatrics and neonatology, and epidemiology. More recently we h~ve seen an emergence of interest in other fields such as perinatal physiology and postnatal behavior which have now become incorporated into the mainstream of research in this discipline. The present volume is an effort to provide a sampling of concepts currently under active investigation in several of the above fields. The authors have endeavored to provide up-to-date in formation on the following topics: detection and analysis of potential hazards to the conceptus in the workplace, pharmacokinetic aspects of the maternal/placental! fetal complex and its relationship to human birth defects, and probable mechanisms of teratogenesis as uncovered in certain well-defined situations. Also included are summaries of newer investigations on the emerging field of postnatal functional evaluations, i. e. , adverse effects on adult activities resultant from in utero exposure to toxic substances.