Test No 490 In Vitro Mammalian Cell Gene Mutation Tests Using The Thymidine Kinase Gene


Test No 490 In Vitro Mammalian Cell Gene Mutation Tests Using The Thymidine Kinase Gene
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Test No 490 In Vitro Mammalian Cell Gene Mutation Tests Using The Thymidine Kinase Gene


Test No 490 In Vitro Mammalian Cell Gene Mutation Tests Using The Thymidine Kinase Gene
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2015-07-28

Test No 490 In Vitro Mammalian Cell Gene Mutation Tests Using The Thymidine Kinase Gene written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-07-28 with categories.


This TG includes two distinct in vitro mammalian gene mutation assays requiring two specific tk heterozygous cells lines: L5178Y tk+/-3.7.2C cells for the mouse lymphoma assay (MLA) and TK6 tk+/- cells for the TK6 assay.



Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 490 In Vitro Mammalian Cell Gene Mutation Tests Using The Thymidine Kinase Gene


Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 490 In Vitro Mammalian Cell Gene Mutation Tests Using The Thymidine Kinase Gene
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Author : OECD
language : en
Publisher: OECD Publishing
Release Date : 2016-07-29

Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 490 In Vitro Mammalian Cell Gene Mutation Tests Using The Thymidine Kinase Gene written by OECD and has been published by OECD Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-07-29 with categories.


This TG includes two distinct in vitro mammalian gene mutation assays requiring two specific tk heterozygous cells lines: L5178Y tk+/-3.7.2C cells for the mouse lymphoma assay (MLA) and TK6 tk+/- cells for the TK6 assay.



Nanotechnology Characterization Tools For Environment Health And Safety


Nanotechnology Characterization Tools For Environment Health And Safety
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Author : Challa S.S.R. Kumar
language : en
Publisher: Springer Nature
Release Date : 2019-11-21

Nanotechnology Characterization Tools For Environment Health And Safety written by Challa S.S.R. Kumar and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-21 with Technology & Engineering categories.


Tenth volume of a 40 volume series on nanoscience and nanotechnology, edited by the renowned scientist Challa S.S.R. Kumar. This handbook gives a comprehensive overview about Nanotechnology Characterization Tools for Environment, Health, and Safety. Modern applications and state-of-the-art techniques are covered and make this volume an essential reading for research scientists in academia and industry.



Animal Models In Research


Animal Models In Research
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Author : Harikrishnan Vijayakumar Sreelatha
language : en
Publisher: Springer Nature
Release Date :

Animal Models In Research written by Harikrishnan Vijayakumar Sreelatha and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.




Materials For Medical Applications


Materials For Medical Applications
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Author : Firdos Alam Khan
language : en
Publisher: CRC Press
Release Date : 2023-09-22

Materials For Medical Applications written by Firdos Alam Khan and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-22 with Technology & Engineering categories.


This book discusses advanced knowledge about the synthesis and application of materials in the medical field for diagnostic and therapeutic conditions. These materials have been extensively used in various biological and medical applications, especially in drug delivery, tumor screening, bioimaging, diagnosis, and therapies. Materials for Medical Applications provides comprehensive but concise information about materials and their medical applications. The readers will get information about the trends in materials and their medical applications, as well as current material-based products that are used in the medical field. The book has 11 chapters, where shapes, sizes, and structural differences of materials and methods of synthesis have been described, and a few chapters are also dedicated to the characterization of materials and their medical applications. The book also discusses how materials are tested in research laboratories, preclinical (animal) trials, and clinical (human) trials, and how material-based products go through various regulatory and safety phases before reaching patients. It also discusses topics such as materials delivery, imaging, and treatments for various diseases. It includes a chapter dedicated to regulatory guidelines and policies in the application of nanomaterials and will include current clinical trial information on the materials. Finally, the book has topics such as health safety, toxicity, dosages, and long-term implications of materials. This book is intended for researchers, material scientists, and students in bioengineering, biomedical engineering, and biopharmaceuticals working on the development of biomaterials.



Nanocosmetics


Nanocosmetics
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Author : Arun Nanda
language : en
Publisher: Elsevier
Release Date : 2020-05-06

Nanocosmetics written by Arun Nanda and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-06 with Technology & Engineering categories.


Nanotechnology is key to the design and manufacture of the new generation of cosmetics. Nanotechnology can enhance the performance and properties of cosmetics, including colour, transparency, solubility, texture, and durability. Sunscreen products, such as UV nano-filters, nano-TiO2 and nano-ZnO particles, can offer an advantage over their traditional counterparts due to their broad UV-protection and non-cutaneous side effects. For perfumes, nano-droplets can be found in cosmetic products including Eau de Toilette and Eau de Parfum. Nanomaterials can also be used in cosmetics as transdermal drug delivery systems. By using smart nanocontainers, active compounds such as vitamins, antioxidants, nutrients, and anti-inflammatory, anti-infective agents, can be delivered effectively. These smart nanocontainers are typically related with the smart releasing property for their embedded active substances. These smart releases could be obtained by using the smart coatings as their outer nano-shells. These nano-shells could prevent the direct contact between these active agents and the adjacent local environments. Nanocosmetics: Fundamentals, Applications and Toxicity explores the formulation design concepts and emerging applications of nanocosmetics. The book also focuses on the mitigation or prevention of their potential nanotoxicity, potential global regulatory challenges, and the technical challenges of mass implementation. It is an important reference source for materials scientists and pharmaceutical scientists looking to further their understanding of how nanotechnology is being used for the new generation of cosmetics. Outlines the major fabrication and formulation design concepts of nanoscale products for cosmetic applications Explores how nanomaterials can safely be used for various applications in cosmetic products Assesses the major challenges of using nanomaterials for cosmetic applications on a large scale



Safety Evaluation Of Certain Food Additives Prepared By The Ninety Sixth Meeting Of The Joint Fao Who Expert Committee On Food Additives Jecfa


Safety Evaluation Of Certain Food Additives Prepared By The Ninety Sixth Meeting Of The Joint Fao Who Expert Committee On Food Additives Jecfa
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Author : World Health Organization
language : en
Publisher: Food & Agriculture Org. [Author] [Author]
Release Date : 2024-05-30

Safety Evaluation Of Certain Food Additives Prepared By The Ninety Sixth Meeting Of The Joint Fao Who Expert Committee On Food Additives Jecfa written by World Health Organization and has been published by Food & Agriculture Org. [Author] [Author] this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-05-30 with Science categories.


The monographs contained in this volume were prepared at the ninety-sixth meeting of the Joint Food and Agriculture Organization of the United Nations (FAO)/World Health Organization (WHO) Expert Committee on Food Additives (JECFA), which met at WHO headquarters in Geneva, Switzerland, on 27 June–6 July 2023. [Author] These monographs summarize the data on specific food additives, including flavouring agents, reviewed by the Committee. [Author]



Safety Evaluation Of Certain Food Additives


Safety Evaluation Of Certain Food Additives
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Author : World Health Organization
language : en
Publisher: World Health Organization
Release Date : 2023-10-02

Safety Evaluation Of Certain Food Additives written by World Health Organization and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-02 with Medical categories.




Safety Evaluation Of Certain Food Additives Prepared By The Ninety Fifth Meeting Of The Joint Fao Who Expert Committee On Food Additives Jecfa


Safety Evaluation Of Certain Food Additives Prepared By The Ninety Fifth Meeting Of The Joint Fao Who Expert Committee On Food Additives Jecfa
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Author : World Health Organization
language : en
Publisher: Food & Agriculture Org.
Release Date : 2023-10-04

Safety Evaluation Of Certain Food Additives Prepared By The Ninety Fifth Meeting Of The Joint Fao Who Expert Committee On Food Additives Jecfa written by World Health Organization and has been published by Food & Agriculture Org. this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-04 with Nature categories.


This volume contains monographs prepared at the ninety-fifth meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), which met virtually during 6–17 and 22 June 2022. The toxicological and dietary exposure monographs in this volume summarize the safety and dietary exposure data on eight specific food additives: α-amlyase (JECFA95-1 and JECFA95-2) from Geobacillus stearothermophilus expressed in Bacillus licheniformis; α-amlyase (JECFA95-3) from Rhizomucor pusillus expressed in Aspergillus niger; amyloglucosidase (JECFA95-4) from Rasamsonia emersonii expressed in Aspergillus niger; asparaginase (JECFA95-5) from Pyrococcus furiosus expressed in Bacillus subtilis; β-amylase (JECFA95-6) from Bacillus flexus expressed in Bacillus licheniformis; lipase (JECFA95-7) from Thermomyces lanuginosus and Fusarium oxysporum expressed in Aspergillus oryzaei; and xylanase (JECFA95-9) from Bacillus licheniformis expressed in Bacillus licheniformis. An addendum summarizes the safety and dietary exposure data on a group of related flavouring agents (alicyclic ketones, secondary alcohols and related esters). This volume and others in the WHO Food Additives series contain information that is useful to those who produce and use food additives and veterinary drugs, those involved in the control of contaminants in food, government and food regulatory officers, industrial testing laboratories, toxicological laboratories and universities.



The Environment Animal Human Web A One Health View Of Toxicological Risk Analysis


The Environment Animal Human Web A One Health View Of Toxicological Risk Analysis
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Author : Chiara Frazzoli
language : en
Publisher: Frontiers Media SA
Release Date : 2019-04-09

The Environment Animal Human Web A One Health View Of Toxicological Risk Analysis written by Chiara Frazzoli and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-09 with categories.


One Health (OH) is the conceptual and operational framework that links environment, food-producing organisms and human health. OH is a developing field, that deals with the multifaceted web of feed-backs and interactions among its components. In order to avoid “drowning into complexity”, priority issues should be identified, either for research and for risk analysis. To date OH approaches have frequently pivoted on infectious agents shared among animals and humans and the related problems, such as antibiotic resistance. Nevertheless, the OH scenarios include, and should increasingly include, environment-and-health problems. Food and environment do interact. Environment influences the living organisms that produce human food and, in the meanwhile, food production outputs influence the environmental quality; as for foods of animal origin, feed materials and practices are driving components of the environment-food interactions. In this book, we aimed at highlighting the importance of environment, chemical exposures and toxicological issues in the field of OH, as well as the need for multidisciplinary integration in order to support OH approaches into diseases prevention and health promotion.