Thalassemia Syndromes New Insights And Transfusion Modalities


Thalassemia Syndromes New Insights And Transfusion Modalities
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Thalassemia Syndromes


Thalassemia Syndromes
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Author : Marwa Zakaria
language : en
Publisher: BoD – Books on Demand
Release Date : 2023-11-22

Thalassemia Syndromes written by Marwa Zakaria and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-22 with Medical categories.


The thalassemia syndromes are a diverse group of hereditary anemias caused by decreased or absent production of one type of globin chain. Genetic counseling, prenatal diagnosis, and newborn screening are all issues of importance in these inherited disorders. This book provides a comprehensive overview of thalassemia, including information on its mechanisms and treatment modalities. Chapters elucidate the mechanism of disordered synthesis of hemoglobin in thalassemia and present recent studies of the genetic mechanisms that underlie this abnormal biosynthetic process.



Beta Thalassemia


Beta Thalassemia
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Author : Marwa Zakaria
language : en
Publisher: BoD – Books on Demand
Release Date : 2020-09-23

Beta Thalassemia written by Marwa Zakaria and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-23 with Medical categories.


Beta thalassemia is a common blood disorder worldwide. Thousands of infants with beta thalassemia are born each year. This book covers most of the aspects related to this disease and greatly helps in understanding this disease and its complications. Of interest are clinical studies as well as basic and translational research reports regarding pathogenesis, genetics, diagnosis as well as standard and novel therapies. This book intends to provide the reader with a comprehensive overview of today’s practices and tomorrow’s possibilities about beta thalassemia.



Guidelines For The Management Of Non Transfusion Dependent Thalassaemia Ntdt


Guidelines For The Management Of Non Transfusion Dependent Thalassaemia Ntdt
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Author : Ali Taher
language : en
Publisher:
Release Date : 2017

Guidelines For The Management Of Non Transfusion Dependent Thalassaemia Ntdt written by Ali Taher and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with Iron deficiency anemia categories.




Iron Chelation Therapy


Iron Chelation Therapy
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Author : Chaim Hershko
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Iron Chelation Therapy written by Chaim Hershko and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.


Within the last few years, iron research has yielded exciting new insights into the under standing of normal iron homeostasis. However, normal iron physiology offers little protec tion from the toxic effects of pathological iron accumulation, because nature did not equip us with effective mechanisms of iron excretion. Excess iron may be effectively removed by phlebotomy in hereditary hemochromatosis, but this method cannot be applied to chronic anemias associated with iron overload. In these diseases, iron chelating therapy is the only method available for preventing early death caused mainly by myocardial and hepatic iron toxicity. Iron chelating therapy has changed the quality of life and life expectancy of thalassemic patients. However, the high cost and rigorous requirements of deferoxamine therapy, and the significant toxicity of deferiprone underline the need for the continued development of new and improved orally effective iron chelators. Such development, and the evolution of improved strategies of iron chelating therapy require better understanding of the pathophysiology of iron toxicity and the mechanism of action of iron chelating drugs. The timeliness of the present volume is underlined by several significant develop ments in recent years. New insights have been gained into the molecular basis of aberrant iron handling in hereditary disorders and the pathophysiology of iron overload (Chapters 1-5).



The Obstetric Hematology Manual


The Obstetric Hematology Manual
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Author : Sue Pavord
language : en
Publisher: Cambridge University Press
Release Date : 2010-04-15

The Obstetric Hematology Manual written by Sue Pavord and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-04-15 with Medical categories.


Obstetric hematology is a fast-growing area of medicine covering the diagnosis and management of hematological problems of pregnancy. Comprehensive in approach, The Obstetric Hematology Manual addresses the many hematological conditions that can cause serious problems in pregnancy, delivery and the post-partum period for both mother and baby. Written by a team of international authorities, this text provides up-to-date, evidence-based guidelines on best care, as well as sound advice based on the experience and opinion of experts. Where appropriate, basic principles are discussed to clarify the rationale for management, and systems and procedures for disease prevention are highlighted. Many conditions and cases are discussed, including venous thromboembolism, pre-eclampsia, anemia, thrombocytopenia and inherited disorders. This book will appeal to both trainees and practitioners in obstetrics, obstetric medicine, obstetric anesthesia and hematology. It is also an accessible text for midwives, nurses, and laboratory staff.



Guidelines For The Clinical Management Of Thalassaemia


Guidelines For The Clinical Management Of Thalassaemia
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Author : Maria-Domenica Cappellini
language : en
Publisher:
Release Date : 2008

Guidelines For The Clinical Management Of Thalassaemia written by Maria-Domenica Cappellini and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with categories.




Thalassemia And Other Hemolytic Anemias


Thalassemia And Other Hemolytic Anemias
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Author : Isam Jaber Al-Zwaini
language : en
Publisher: BoD – Books on Demand
Release Date : 2018-07-11

Thalassemia And Other Hemolytic Anemias written by Isam Jaber Al-Zwaini and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-11 with Medical categories.


Thalassemia is a very common disease first described by pediatrician Thomas Benton Cooley in 1925 who described it in a patient of Italian origin. At that time, it was designated as Cooley's anemia. George Hoyt Whipple, a Nobel prize winner, and W. L. Bradford, a professor of pediatrics at the University of Rochester, coined the term thalassemia in 1936, which in Greek means anemia of the sea (Thalassa means "sea", and emia means "blood"), due to the fact that it is very common in the area of the Mediterranean Sea. This name is actually misleading because it can occur everywhere in the world. Thalassemia is not a single disease; it is rather a group of hereditary disorders of the production of globulin chain of the hemoglobin. Throughout the world, thalassemia affects approximately 4.4 of every 10,000 live births. It represents a major social and emotional impact on the patient and his family and a major burden on health services where the prevalence is high.



Newborn Screening For Sickle Cell Disease And Other Haemoglobinopathies


Newborn Screening For Sickle Cell Disease And Other Haemoglobinopathies
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Author : Stephan Lobitz
language : en
Publisher: MDPI
Release Date : 2019-10-07

Newborn Screening For Sickle Cell Disease And Other Haemoglobinopathies written by Stephan Lobitz and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-07 with Medical categories.


Newborn Screening for Sickle Cell Disease and other Haemoglobinopathies is a Special Issue of the International Journal of Neonatal Screening. Sickle cell disease is one of the most common inherited blood disorders, with a huge impact on health care systems due to high morbidity and high mortality associated with the undiagnosed disease. Newborn screening helps to make the diagnosis early and to prevent fatal complications and diagnostic odysseys. This book gives an overview of diagnostic standards in newborn screening for sickle cell disease and examples of existing newborn screening programs.



Thalassemia New Insights For The Healthcare Professional 2013 Edition


Thalassemia New Insights For The Healthcare Professional 2013 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2013-07-22

Thalassemia New Insights For The Healthcare Professional 2013 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-07-22 with Medical categories.


Thalassemia: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Diagnosis and Screening in a concise format. The editors have built Thalassemia: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Diagnosis and Screening in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Thalassemia: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.



Rossi S Principles Of Transfusion Medicine


Rossi S Principles Of Transfusion Medicine
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Author : Toby L. Simon
language : en
Publisher: John Wiley & Sons
Release Date : 2016-05-23

Rossi S Principles Of Transfusion Medicine written by Toby L. Simon and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-05-23 with Medical categories.


Rossi's Principles of Transfusion Medicine is the most comprehensive and practical reference on transfusion science and medicine available Led by a world class Editor team, including two past-presidents of AABB, a past- President of the American Board of Pathology and members of the FDA Blood Products Advisory Committee , and international contributor team Comprehensive reference resource, considered the gold standard in transfusion Covers current hot topics such as donor care – including the frequency of donation and management of iron deficiency/status), patient blood management, hemovigilance, cstem cell therapies, and global aspects of the organization of transfusion and transplant services New material on molecular immunohematology Companion website includes figures, full text and references