The Advances And Applications Of Optogenetics
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The Advances And Applications Of Optogenetics
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Author : Elena G. Govorunova
language : en
Publisher: MDPI
Release Date : 2020-12-28
The Advances And Applications Of Optogenetics written by Elena G. Govorunova and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-28 with Science categories.
This book provides an update for the rapidly developing technology known as “optogenetics”, which is the use of genetically encoded light-sensitive molecular elements (usually derived from lower organisms) to control or report various physiological and biochemical processes within the cell. Two ongoing clinical trials use optogenetic tools for vision restoration, and optogenetic strategies have been suggested as novel therapies for several neurological, psychiatric and cardiac disorders. This Special Issue comprises two reviews and seven experimental papers on different types of light-sensitive modules widely used in optogenetic studies. These papers demonstrate the efficiency and versatility of optogenetics and are expected to be equally relevant for advanced users and beginners considering using optogenetic tools in their research.
Optogenetics
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Author : Hiromu Yawo
language : en
Publisher: Springer Nature
Release Date : 2021-01-05
Optogenetics written by Hiromu Yawo and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-01-05 with Medical categories.
This book, now in a thoroughly revised second edition, offers a comprehensive review of the rapidly growing field of optogenetics, in which light-sensing proteins are genetically engineered into cells in order to acquire information on cellular physiology in optical form or to enable control of specific network in the brain upon activation by light. Light-sensing proteins of various living organisms are now available to be exogenously expressed in neurons and other target cells both in vivo and in vitro. Cellular functions can thus be manipulated or probed by light. The new edition documents fully the extensive progress since publication of the first edition to provide an up-to-date overview of the physical, chemical, and biological properties of light-sensing proteins and their application in biological systems, particularly in neuroscience but also in medicine and the optical sciences. Underlying principles are explained and detailed information provided on a wide range of optogenetic tools for the observation and control of cellular signaling and physiology, gene targeting technologies, and optical methods for biological applications. In presenting the current status of optogenetics and emerging directions, this milestone publication will be a “must read” for all involved in research in any way related to optogenetics.
The Advances And Applications Of Optogenetics
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Author : Elena G. Govorunova
language : en
Publisher:
Release Date : 2020
The Advances And Applications Of Optogenetics written by Elena G. Govorunova and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with categories.
This book provides an update for the rapidly developing technology known as “optogenetics”, which is the use of genetically encoded light-sensitive molecular elements (usually derived from lower organisms) to control or report various physiological and biochemical processes within the cell. Two ongoing clinical trials use optogenetic tools for vision restoration, and optogenetic strategies have been suggested as novel therapies for several neurological, psychiatric and cardiac disorders. This Special Issue comprises two reviews and seven experimental papers on different types of light-sensitive modules widely used in optogenetic studies. These papers demonstrate the efficiency and versatility of optogenetics and are expected to be equally relevant for advanced users and beginners considering using optogenetic tools in their research.
Lighting Up The Brain
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Author : Marc Zimmer
language : en
Publisher: Twenty-First Century Books TM
Release Date : 2018-01-01
Lighting Up The Brain written by Marc Zimmer and has been published by Twenty-First Century Books TM this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-01 with Young Adult Nonfiction categories.
What if neuroscientists could look inside the human brain and watch individual brain cells send signals to one another? What if they could then control these brain cells to direct thoughts and actions? This may sound like science fiction, but it's actually a scientific revolution called optogenetics. Neuroscientists would like to use this new technology on human brains to uncover secrets about how the brain processes information and drives human behavior. Doctors hope to use optogenetics to restore sight and to treat Alzheimer's disease, Parkinson's disease, depression, and other debilitating or deadly health problems. Discover how the innovative work of leaders in the field is poised to radically transform science, medicine, and human health.
The Dynamic Nature Of Mitochondria
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Author : Andreas S. Reichert
language : en
Publisher: CRC Press
Release Date : 2024-04-15
The Dynamic Nature Of Mitochondria written by Andreas S. Reichert and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-15 with Science categories.
Mitochondrial research has exploded over the last ~150 years. This book gives an amazing view on a conceptual change in our understanding of mitochondrial biology. It becomes clear that mitochondria are extremely dynamic in nature, controlling life at multiple levels. Mitochondria rule energy conversion, adapt cells well to changing stress and nutrient conditions, and regulate many cellular processes including immunity. The dynamic nature of mitochondria occurs at an intramitochondrial level but also includes its ability to interact with other organelles and to modulate multiple signalling pathways. It is thus not surprising that alterations or inabilities to ensure this dynamic behaviour is linked to ageing and human diseases. The following sections give an updated view on mitochondria: Mitochondrial ultrastructure: molecular mechanisms shaping the inner membrane Mitochondrial cristae and lipid dynamics: from super-resolution microscopy to lipid-OXPHOS interplay Mitochondrial control of cellular homeostasis: from redox signalling to interorganellar contact sites Mitochondria in health and disease: from mtDNA release to Complex I assembly Advanced methods in mitochondrial biology and metabolism research Integrative view on mitochondrial research and outlook The field of mitochondrial research has always been full of surprises and has helped science to advance tremendously. It developed hand in hand with landmark developments in technology, such as super-resolution microscopy (nanoscopy), and is currently influencing an increasing number of scientific disciplines. There is still much ‘new’ to find out about this ‘old’ organelle and I think that you can find interesting and also unexpected aspects of mitochondrial biology in this book. I hope the book will enhance your scientific curiosity and inspire your own research.
Optogenetics
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Author : Peter Hegemann
language : en
Publisher: Walter de Gruyter
Release Date : 2013-08-28
Optogenetics written by Peter Hegemann and has been published by Walter de Gruyter this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-08-28 with Science categories.
Optogenetics combines genetic engineering with optics to observe and control the function of cells using light, with clinical implications for restoration of vision and treatment of neurological diseases. As a new discipline much of the basic science and methods are currently under investigation and active development, thus there is a strong need for introductory literature in this field. This graduate level textbook provides an overview of the field of optogenetics in 5 concise chapters: Optogenetic tools, Applications in cellular systems, Mapping neuronal networks, Clinical applications and Restoration of vision and hearing. The concept and content was developed with top international researchers and students at a prestigious Dahlem Conference workshop.
Shedding Light On The Nervous System Progress In Neurophotonics Research
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Author : Jean-Claude Béïque
language : en
Publisher: Frontiers Media SA
Release Date : 2022-07-01
Shedding Light On The Nervous System Progress In Neurophotonics Research written by Jean-Claude Béïque and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-01 with Science categories.
Advances In Physiology Research And Application 2012 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-12-26
Advances In Physiology Research And Application 2012 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-26 with Medical categories.
Advances in Physiology Research and Application / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Physiology. The editors have built Advances in Physiology Research and Application / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Physiology in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Physiology Research and Application / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Developments And Applications In Smartrail Traffic And Transportation Engineering
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Author : Limin Jia
language : en
Publisher: Springer Nature
Release Date : 2024-08-13
Developments And Applications In Smartrail Traffic And Transportation Engineering written by Limin Jia and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-08-13 with Technology & Engineering categories.
This book is a collection of original peer-reviewed contributions from the 2023 International Conference on SmartRail, Traffic, and Transportation Engineering, jointly organized by Beijing Jiaotong University, China Electrotechnical Society, Chinese Institute of Electronics and Central South University. It was held on July 28-30, 2023 in Changsha, China. Topics covered includes SmartRail systems, autonomous vehicles, energy efficiency, sustainable transportation, big data in transportation, and machine learning. Speakers discussed innovative technologies and strategies to improve the efficiency, reliability, and safety of rail networks, while exploring the opportunities and challenges of integrating autonomous vehicles into existing transportation networks. It provides valuable insights into the latest developments and trends in transportation engineering and technology, with a focus on electrification and sustainable transportation. It serves as a valuable resource for professionals, researchers, and students working in the field.
Optogenetics
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Author :
language : en
Publisher: Elsevier
Release Date : 2012-12-06
Optogenetics written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Optogenetics is a fast-growing field concerning the invention, and use, of molecules that are genetically expressed in cells, and then either report on cellular physiology in optical form, or enable control of specific pathways in cells when actuated by light. This book reviews the current state, as well as the underlying principles and future directions, of a diversity of optogenetic tools of importance for observing and controlling cellular signaling and physiology. These tools are already revolutionizing neuroscience, and are starting to have impact on fields ranging from metabolism to development to cardiology. The book contains a dozen chapters written by world experts on these topics, half focusing on the optogenetic molecular tools themselves, and half on the genetic and hardware approaches that make them powerfully useful in intact tissues and organisms. - Leading authors review the state-of-the-art in their field of investigation and provide their views and perspectives for future research - Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered - All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist