The Dynamic Nature Of Mitochondria
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The Dynamic Nature Of Mitochondria
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Author : Andreas S. Reichert
language : en
Publisher: CRC Press
Release Date : 2024-04-15
The Dynamic Nature Of Mitochondria written by Andreas S. Reichert and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-15 with Science categories.
Mitochondrial research has exploded over the last ~150 years. This book gives an amazing view on a conceptual change in our understanding of mitochondrial biology. It becomes clear that mitochondria are extremely dynamic in nature, controlling life at multiple levels. Mitochondria rule energy conversion, adapt cells well to changing stress and nutrient conditions, and regulate many cellular processes including immunity. The dynamic nature of mitochondria occurs at an intramitochondrial level but also includes its ability to interact with other organelles and to modulate multiple signalling pathways. It is thus not surprising that alterations or inabilities to ensure this dynamic behaviour is linked to ageing and human diseases. The following sections give an updated view on mitochondria: Mitochondrial ultrastructure: molecular mechanisms shaping the inner membrane Mitochondrial cristae and lipid dynamics: from super-resolution microscopy to lipid-OXPHOS interplay Mitochondrial control of cellular homeostasis: from redox signalling to interorganellar contact sites Mitochondria in health and disease: from mtDNA release to Complex I assembly Advanced methods in mitochondrial biology and metabolism research Integrative view on mitochondrial research and outlook The field of mitochondrial research has always been full of surprises and has helped science to advance tremendously. It developed hand in hand with landmark developments in technology, such as super-resolution microscopy (nanoscopy), and is currently influencing an increasing number of scientific disciplines. There is still much ‘new’ to find out about this ‘old’ organelle and I think that you can find interesting and also unexpected aspects of mitochondrial biology in this book. I hope the book will enhance your scientific curiosity and inspire your own research.
The Dynamic Nature Of Mitochondria
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Author : Andreas S. Reichert
language : en
Publisher:
Release Date : 2024
The Dynamic Nature Of Mitochondria written by Andreas S. Reichert and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024 with Medical categories.
"Mitochondrial research has exploded over the last 150 years. This book gives an amazing view on a conceptual change in our understanding of mitochondrial biology. It becomes clear that mitochondria are extremely dynamic in nature controlling life at multiple levels. Mitochondria rule energy conversion, adapt cells well to changing stress and nutrient conditions, and regulate many cellular processes including immunity. The dynamic nature of mitochondria occurs at an intramitochondrial level but also includes its ability to interact with other organelles and to modulate multiple signalling pathways. It is thus not surprising that alterations or inabilities to ensure this dynamic behaviour is linked to ageing and human diseases"--
Mitochondrial Dynamics And Neurodegeneration
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Author : Bingwei Lu
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-05-16
Mitochondrial Dynamics And Neurodegeneration written by Bingwei Lu and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-05-16 with Science categories.
Mitochondria are essential organelles in eukaryotic cells that control such diverse processes as energy metabolism, calcium buffering, and cell death. Recent studies have revealed that changes in mitochondrial morphology by fission and fusion, a process known as mitochondrial dynamics, is particularly important for neuronal function and survival. Defects in this process are commonly found in neurodegenerative diseases, offering a new paradigm for investigating mechanisms of neurodegeneration. To provide researchers working on neurodegenerative diseases and mitochondria with updated information on this rapidly progressing field, we have invited experts in the field to critically review recent progresses and identify future research directions. The topics include genetics of mitochondrial dynamics, mitochondrial dynamics and bioenergetics, autophagy, apoptosis, and axonal transport, and its role in neurological diseases, including Alzheimer’s, Parkinson’s, and Huntington’s diseases.
Mitochondrial Remodeling And Dynamic Inter Organellar Contacts In Cardiovascular Physiopathology
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Author : Giampaolo Morciano
language : en
Publisher: Frontiers Media SA
Release Date : 2021-06-21
Mitochondrial Remodeling And Dynamic Inter Organellar Contacts In Cardiovascular Physiopathology written by Giampaolo Morciano and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-21 with Science categories.
Mitochondrial Oxphos System Emerging Concepts And Technologies And Role In Disease
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Author : David Pacheu-Grau
language : en
Publisher: Frontiers Media SA
Release Date : 2022-06-06
Mitochondrial Oxphos System Emerging Concepts And Technologies And Role In Disease written by David Pacheu-Grau and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-06 with Science categories.
Mitochondrial Biology And Experimental Therapeutics
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Author : Paulo J. Oliveira
language : en
Publisher: Springer
Release Date : 2018-03-21
Mitochondrial Biology And Experimental Therapeutics written by Paulo J. Oliveira and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-21 with Medical categories.
This book addresses the therapeutic strategies to target mitochondrial metabolism in diseases where the function of that organelle is compromised, and it discusses the effective strategies used to create mitochondrial-targeted agents that can become commercially available drug delivery platforms. The consistent growth of research focused in understanding the multifaceted role of mitochondria in cellular metabolism, controlling pathways related with cell death, and ionic/redox regulation has extended the research of mitochondrial chemical-biological interactions to include various pharmacological and toxicological applications. Not only does the book extensively cover basic mitochondrial physiology, but it also links the molecular interactions within these pathways to a variety of diseases. It is one of the first books to combine state-of-the-art reviews regarding basic mitochondrial biology, the role of mitochondrial alterations in different diseases, and the importance of that organelle as a target for pharmacological and non-pharmacological interventions to improve human health. The different chapters highlight the chemical-biological linkages of the mitochondria in context with drug development and clinical applications.
Mitochondrial Dna Mitochondria Disease And Stem Cells
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Author : Justin C. St. John
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-09-26
Mitochondrial Dna Mitochondria Disease And Stem Cells written by Justin C. St. John and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-09-26 with Science categories.
This volume investigates how the mitochondrial genome is transmitted, segregated, and inherited. It starts by describing mtDNA mutations and deletions and how these impact on the offspring’s well-being. It progresses to discuss how mutations to the mtDNA-nuclear-encoded transcription, replication and translational factors lead to mtDNA-depletion syndromes and how these affect cellular function and lead to the pathology of human mitochondrial disease. It also highlights the importance of the mitochondrial assembly factors and how mutations to these can lead to mitochondrial disease. The reader is then introduced to how mtDNA is transmitted through the oocyte and how stem cells can be used to study mitochondrial biogenesis and mtDNA replication and transcription in undifferentiated pluripotent and differentiating cells and how mitochondria adapt during this process. It then discusses how diseases like cancer are initiated and regulated by mutations to mitochondrial DNA and dysfunctional mitochondria. Finally, it draws on assisted reproductive technologies to discuss how some of these approaches might be adapted to prevent the transmission of mutant and deleted mtDNA from one generation to the next.
International Review Of Cell And Molecular Biology
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Author : Kwang W. Jeon
language : en
Publisher: Academic Press
Release Date : 2010-11-19
International Review Of Cell And Molecular Biology written by Kwang W. Jeon and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-19 with Science categories.
International Review of Cell and Molecular Biology presents current advances and comprehensive reviews in cell biology--both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Impact factor for 2008: 4.935. - Authored by some of the foremost scientists in the field - Provides up-to-date information and directions for future research - Valuable reference material for advanced undergraduates, graduate students and professional scientists
Mitochondrial Function Part B
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Author :
language : en
Publisher: Academic Press
Release Date : 2009-05-05
Mitochondrial Function Part B written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-05-05 with Science categories.
In this second of two new volumes covering mitochondria, methods developed to assess the number and function of nuclear-encoded proteins in the mitochondrion are presented. Chapters focus on the regulation of mitochondrial function and mitochondrial diseases, with a section emphasizing the mitochondrial defects associated with type 2 diabetes. The critically acclaimed laboratory standard for 40 years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. With more than 450 volumes published, each volume presents material that is relevant in today's labs, truly an essential publication for researchers in all fields of life sciences. - New methods focusing on the examination of normal and abnormal mitochondrial function are presented in an easy-to-follow format by the researchers who developed them - Along with a companion volume covering topics including mitochondrial electron transport chain complexes and reactive oxygen species, provides a comprehensive overview of modern techniques in the study of mitochondrial malfunction - Provides a "one-stop shop" for tried and tested essential techniques, eliminating the need to wade through untested or unreliable methods
Progress In Botany
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Author : K. Esser
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Progress In Botany written by K. Esser and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
With one volume each year, this series keeps scientists and advanced students informed of the latest developments and results in all areas of the plant sciences. The present volume includes reviews on genetics, cell biology, physiology, comparative morphology, systematics, ecology and vegetation science.