The Clinical Application Of Homocysteine
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The Clinical Application Of Homocysteine
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Author : Seema Bhargava
language : en
Publisher: Springer
Release Date : 2018-02-27
The Clinical Application Of Homocysteine written by Seema Bhargava and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-27 with Medical categories.
This book helps clinicians to optimally and appropriately utilize homocysteine levels in the diagnosis, prediction and management of and research into vascular disease and many other conditions. It also familiarizes readers with the pathophysiology and clinical implications of hyperhomocysteinemia. Laboratory investigations are gaining importance in the diagnosis and prognosis of patients, and as such, scientists and laboratorians are constantly attempting to identify new markers that will help in earlier diagnosis and better prognostication of conditions with high morbidity and mortality, as well as high prevalence. According to the WHO, developing countries are home to 80% of patients with coronary artery disease (CAD) and stroke – conditions with a mortality second only to cancer. Intensive research in these areas has resulted in the identification of homocysteine (declared the ‘marker of the millennium’) and several new markers for the diagnosis and prediction of CAD and stroke. The book is a valuable resource for clinicians and consultants in practice, as well as for postgraduate and undergraduate students of medicine, biotechnology and biochemistry.
The Clinical Application Of Homocysteine
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Author : Seema Bhargava (Biochemist)
language : en
Publisher:
Release Date : 2018
The Clinical Application Of Homocysteine written by Seema Bhargava (Biochemist) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with Clinical biochemistry categories.
This book helps clinicians to optimally and appropriately utilize homocysteine levels in the diagnosis, prediction and management of and research into vascular disease and many other conditions. It also familiarizes readers with the pathophysiology and clinical implications of hyperhomocysteinemia. Laboratory investigations are gaining importance in the diagnosis and prognosis of patients, and as such, scientists and laboratorians are constantly attempting to identify new markers that will help in earlier diagnosis and better prognostication of conditions with high morbidity and mortality, as well as high prevalence. According to the WHO, developing countries are home to 80% of patients with coronary artery disease (CAD) and stroke - conditions with a mortality second only to cancer. Intensive research in these areas has resulted in the identification of homocysteine (declared the 'marker of the millennium') and several new markers for the diagnosis and prediction of CAD and stroke. The book is a valuable resource for clinicians and consultants in practice, as well as for postgraduate and undergraduate students of medicine, biotechnology and biochemistry.
Homocysteine And Vascular Disease
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Author : K. Robinson
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-17
Homocysteine And Vascular Disease written by K. Robinson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-17 with Medical categories.
This is an important and timely volume. The history of research in homocysteine metabolism can be divided into three periods. The first phase was the exploration of the individual reactions and metabolites that characterize the transmethylation and transsulfuration sequences. The former originated with his description of the biosynthesis of methylpyridine and culminated in the work of Cantoni and Axelrod. Similarly the finding that insulin contained cystine was a potent catalyst for the metabolic and nutritional studies of Rose and du Vigneaud. The description and the definition of homocystinuria, a rare inherited meta bolic disorder, marked the beginning of the second historical period. Where previously there had been few laboratories located largely in the United States soon there were numerous research groups representing many nationalities. The more intense focus led to major advances, both in the laboratory and in the clinics. Studies of afflicted individuals, when combined with investigations in experimental animals, provided the basis for a concept of methionine metabo lism that encompassed both transmethylation and transsulfuration. The central role of homocysteine was apparent.
Homocysteine In Health And Disease
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Author : Ralph Carmel
language : en
Publisher: Cambridge University Press
Release Date : 2001-07-19
Homocysteine In Health And Disease written by Ralph Carmel and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-07-19 with Medical categories.
This is an unusually comprehensive 2001 account of the broad range of medical implications of homocysteine.
A New Gas Chromatographic Mass Spectrometric Method For The Determination Of Total Plasma Homocysteine And Related Amino Acids
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Author : Joseph Iskendiarso Sigit
language : en
Publisher: Cuvillier Verlag
Release Date : 2001
A New Gas Chromatographic Mass Spectrometric Method For The Determination Of Total Plasma Homocysteine And Related Amino Acids written by Joseph Iskendiarso Sigit and has been published by Cuvillier Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with categories.
Focus On Homocysteine And The Vitamins
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Author : Christina Bolander-Gouaille
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-22
Focus On Homocysteine And The Vitamins written by Christina Bolander-Gouaille and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-22 with Medical categories.
During the last 10-12 years, the research on homocysteine has become very active. About 1500 of articles are now published each year on homocysteine and the vitamins involved in its metabolism. A disturbed homocysteine metabolism can be an underlying factor for pregnancy complications and fetal malformations, cardiovascular disease, dementia, psychiatric and neurologic disorders and possibly carcinogenesis. A disturbed homocysteine metabolism can in most cases be normalised by treatment with folate and/or vitamines B12 and B6. Many of these findings therefore directly concern most practitioners. However, if there are good reviews covering single aspects of this research, these are published in specialised journals. The author has realised the difficulties for the practitioner in keeping updated. This second edition has been thoroughly updated and also offers more data on the vitamins. Over 1600 references are made available.
Laboratory Assessment Of Vitamin Status
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Author : Dominic J. Harrington
language : en
Publisher: Academic Press
Release Date : 2018-11-28
Laboratory Assessment Of Vitamin Status written by Dominic J. Harrington and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-28 with Medical categories.
Laboratory Assessment of Vitamin Status provides a comprehensive understanding of the limitations of commonly used approaches used for the evaluation of vitamin status, reducing harm in the general health setting. It outlines the application of ‘Best Practice’ approaches to the evaluation of vitamin status, giving physicians and other healthcare professionals the opportunity to make evidence-based interventions. Nearly every metabolic and developmental pathway in the human body has a dependency on at least one micronutrient. Currently, the clinical utility of approaches taken by laboratories for the assessment of vitamin status is generally poorly understood, missing the opportunity to diagnosis vitamin deficiencies. This essential reference gives clinical and biomedical scientists an understanding of the limitations of commonly used approaches to the evaluation of vitamin status in the general health setting through change in practice. Nutritionists and dietitians gain an understanding of more sophisticated markers of vitamin status. Describes specialist assays in sufficient detail to enable laboratories to replicate what is being performed by expert groups Provides detailed information that supports laboratories in the setting up of methods for the evaluation of vitamin status Informs laboratories looking for third party providers of specialist investigations Provides an essential overview of reference ranges for each vitamin
Non Proteinogenic Amino Acids
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Author : Nina Filip
language : en
Publisher: BoD – Books on Demand
Release Date : 2018-12-05
Non Proteinogenic Amino Acids written by Nina Filip and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-12-05 with Science categories.
The first description of homocysteine (Hcy), a non-proteinogenic amino acid, was introduced in a case study more than 70 years ago. In recent years, numerous studies have shown a positive correlation between serum levels and various diseases, especially vascular pathology. Vitamins B6, B12, and folic acid play a major role in controlling homocysteine levels. In this book are presented both methods for the determination of homocysteine and its involvement in human pathology. Homocysteine levels can be taken as an early indicator for the detection of cardiovascular diseases because Hcy levels increase after a myocardial infarction or stroke.
The Homocysteine Solution
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Author : Patrick Holford
language : en
Publisher: Hachette UK
Release Date : 2012-07-05
The Homocysteine Solution written by Patrick Holford and has been published by Hachette UK this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-07-05 with Health & Fitness categories.
Your homocysteine level is the single most important statistic you need to know in order to determine how healthy you are and how long you will live. Your 'H level' is now widely understood to be a greater risk factor for heart disease than cholesterol. Homocysteine expert Dr James Braly has shown that a high homocysteine score is a major risk factor for cancer, arthritis and even obesity. In this accessible book Dr Braly and leading nutritionist Patrick Holford show you how to assess your H level and suggest 10 remarkably simple changes to your diet and your lifestyle that will lower your score and dramatically cut your risk of ever having cancer, heart disease, diabetes, arthritis and many more serious ailments. Learn how to: test your homocysteine levels; reduce your risk of disease; slow down the ageing process; improve your health; and radically increase your life expectancy.
Nutritional Management And Metabolic Aspects Of Hyperhomocysteinemia
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Author : Mostafa I. Waly
language : en
Publisher: Springer Nature
Release Date : 2021-03-31
Nutritional Management And Metabolic Aspects Of Hyperhomocysteinemia written by Mostafa I. Waly and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-31 with Medical categories.
Elevated blood concentrations of homocysteine, B vitamins deficiencies and oxidative stress are etiological factors for many human chronic diseases, yet the etiologic relationship of hyperhomocysteinemia to these disorders remains poorly understood. Clinical trials continue to support the notion that hyperhomocysteinemia is involved in the pathogenesis of oxidative stress and its associated impairment of cellular redox status. Antioxidants, phytochemicals, and bioactive agents are thought to be associated with the reduction of oxidative stress and reducing risk of chronic diseases, yet their role in preventing hyperhomocysteinemia-mediated oxidative stress has not been well covered in the literature. Nutritional Management and Metabolic Aspects and of Hyperhomocysteinemia comprehensively covers the nutritional-based intervention for combating hyperhomocysteinemia-mediated oxidative stress, metabolic regulation of homocysteine-dependent transulfuration and transmethylation pathways, and the identification of novel biomarkers for early diagnosis of hyperhomocysteinemia. The main goal of this text is to address the biochemical and nutritional aspects of hyperhomocysteinemia in relation to increasing risk of chronic diseases, providing insight into the etiology of hyperhomocysteinemia and covering new research on the effective reduction and management of hyperhomocysteinemia-associated chronic diseases. For researchers seeking a singular source for the understanding of the biochemical aspects and nutrition-based combat of hyperhomocysteinemia, its risk factors, preventive measures, and possible treatments currently available, this text provides all of the important needed information in up-to-date and comprehensive form.