The Gastrointestinal System Motility And Circulation
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Handbook Of Physiology
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Author : John R. Pappenheimer
language : en
Publisher:
Release Date : 1989
Handbook Of Physiology written by John R. Pappenheimer and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with categories.
The Gastrointestinal System Motility And Circulation
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Author :
language : en
Publisher:
Release Date : 1989
The Gastrointestinal System Motility And Circulation written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Gastrointestinal system categories.
Handbook Of Physiology The Gastrointestinal System V 1 Pt 1 2 Motility And Circulation
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Author :
language : en
Publisher:
Release Date : 1989
Handbook Of Physiology The Gastrointestinal System V 1 Pt 1 2 Motility And Circulation written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Physiology categories.
Handbook Of Physiology
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Author : Stanley G. Schultz
language : en
Publisher: Oxford University Press, USA
Release Date : 1989-08
Handbook Of Physiology written by Stanley G. Schultz and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989-08 with categories.
Since the publication of the first volume on gastrointestinal motility in the Handbook of Physiology (1968), there has been an impressive development of new information, new methods and new understanding of motility. These advances span all levels of organization from single smooth muscle cells and neurons to integrated organ function, and they are expertly documented by the authors of this edition. Parallel progress in understanding the vascular system and lymphatics of the alimentary canal over the past 20 years is reviewed in equal detail. Among the topics given authoritative coverage are the ultrastructure of gastrointestinal smooth muscle, the extracellular matrix, and the mechanical properties of the musculature; electrical and chemical behavior of gut neurons and the immunocytochemical localization of neurotransmitters; the unique pattern of motility in the interdigestive state; measurement of intraluminal pressures and electrical and contractile activity at all levels of the gastrointestinal tract; abnormalities associated with parasitic infections; enterotoxins, emesis and surgical perturbations that shed light on normal mechanisms; the basic structure and ultrastructure of the gut vasculature; regional hemodynamics and regulation of the digestive circulation; and neuromuscular transmission in the gut musculature and its neurohormonal control. Overall, the book provides an unparalleled view of gastrointestinal motor and circulatory function. It will be of great use to a wide spectrum of readers, including physiologists, gastroenterologists, graduate students, and postdoctoral fellows
The Gastrointestinal System
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Author : Stanley G. Schultz
language : en
Publisher:
Release Date : 1989
The Gastrointestinal System written by Stanley G. Schultz and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Bile categories.
Handbook Of Physiology
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Author : Schultz, Stanley J.W. Marion
language : en
Publisher: Oxford University Press
Release Date : 1991-10-17
Handbook Of Physiology written by Schultz, Stanley J.W. Marion and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991-10-17 with Medical categories.
The four volumes of The Handbook of Physiology, Section 6: The Gastrointestinal System constitute another milestone in the rapidly progressing field of gastrointestinal science. No other work gives the subject such in-depth coverage or such contemporary treatment. Volume I deals with the motor function and the circulatory system of the alimentary tract. Volume II represents the first comprehensive, systematic account of the hormonal and neural peptides of the gut. Volume III covers the cellular basis of secretion along with the broader, more integrative aspects of the process. Volume IV provides a thorough survey of the processes and regulatory mechanisms linked to intestinal absorption and secretion.
Colonic Motility
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Author : Sushil K. Sarna
language : en
Publisher: Biota Publishing
Release Date : 2010-11-01
Colonic Motility written by Sushil K. Sarna and has been published by Biota Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-01 with Medical categories.
Three distinct types of contractions perform colonic motility functions. Rhythmic phasic contractions (RPCs) cause slow net distal propulsion with extensive mixing/turning over. Infrequently occurring giant migrating contractions (GMCs) produce mass movements. Tonic contractions aid RPCs in their motor function. The spatiotemporal patterns of these contractions differ markedly. The amplitude and distance of propagation of a GMC are several-fold larger than those of an RPC. The enteric neurons and smooth muscle cells are the core regulators of all three types of contractions. The regulation of contractions by these mechanisms is modifiable by extrinsic factors: CNS, autonomic neurons, hormones, inflammatory mediators, and stress mediators. Only the GMCs produce descending inhibition, which accommodates the large bolus being propelled without increasing muscle tone. The strong compression of the colon wall generates afferent signals that are below nociceptive threshold in healthy subjects. However, these signals become nociceptive; if the amplitudes of GMCs increase, afferent nerves become hypersensitive, or descending inhibition is impaired. The GMCs also provide the force for rapid propulsion of feces and descending inhibition to relax the internal anal sphincter during defecation. The dysregulation of GMCs is a major factor in colonic motility disorders: irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and diverticular disease (DD). Frequent mass movements by GMCs cause diarrhea in diarrhea predominant IBS, IBD, and DD, while a decrease in the frequency of GMCs causes constipation. The GMCs generate the afferent signals for intermittent short-lived episodes of abdominal cramping in these disorders. Epigenetic dysregulation due to adverse events in early life is one of the major factors in generating the symptoms of IBS in adulthood.
The Gastrointestinal Circulation
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Author : Peter R. Kvietys
language : en
Publisher: Morgan & Claypool Publishers
Release Date : 2010
The Gastrointestinal Circulation written by Peter R. Kvietys and has been published by Morgan & Claypool Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Medical categories.
The microcirculation of the gastrointestinal tract is under the control of both myogenic and metabolic regulatory systems. The myogenic mechanism contributes to basal vascular tone and the regulation of transmural pressure, while the metabolic mechanism is responsible for maintaining an appropriate balance between O2 demand and O2 delivery. In the postprandial state, hydrolytic products of food digestion elicit a hyperemia, which serves to meet the increased O2 demand of nutrient assimilation. Metabolically linked factors (e.g., tissue pO2, adenosine) are primarily responsible for this functional hyperemia. The fenestrated capillaries of the gastrointestinal mucosa are relatively permeable to small hydrolytic products of food digestion (e.g., glucose), yet restrict the transcapillary movement of larger molecules (e.g., albumin). This allows for the absorption of hydrolytic products of food digestion without compromising the oncotic pressure gradient governing transcapillary fluid movement and edema formation. The gastrointestinal microcirculation is also an important component of the mucosal defense system whose function is to prevent (and rapidly repair) inadvertent epithelial injury by potentially noxious constituents of chyme. Two pathological conditions in which the gastrointestinal circulation plays an important role are ischemia/reperfusion and chronic portal hypertension. Ischemia/reperfusion results in mucosal edema and disruption of the epithelium due, in part, to an inflammatory response (e.g., increase in capillary permeability to macromolecules and neutrophil infiltration). Chronic portal hypertension results in an increase in gastrointestinal blood flow due to an imbalance in vasodilator and vasoconstrictor influences on the microcirculation. Table of Contents: Introduction / Anatomy / Regulation of Vascular Tone and Oxygenation / Extrinsic Vasoregulation: Neural and Humoral / Postprandial Hyperemia / Transcapillary Solute Exchange / Transcapillary Fluid Exchange / Interaction of Capillary and Interstitial Forces / Gastrointestinal Circulation and Mucosal Defense / Gastrointestinal Circulation and Mucosal Pathology I: Ischemia/Reperfusion / Gastrointestinal Circulation and Mucosal Pathology II: Chronic Portal Hypertension / Summary and Conclusions / References / Author Biography
Gastrointestinal Motility
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Author : D. Grundy
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Gastrointestinal Motility written by D. Grundy and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The basis of this book is a ten-lecture course on the control of gastrointesti nal motility given each year to the final year undergraduate students in Physiology at Sheffield University. A naive thought led me to believe that the conversion of my lecture notes into the present book would be a relatively easy task. I now know differently. As there is no equivalent undergraduate course elsewhere that I know of, it would be dishonest of me to claim this book to be an undergraduate text. The comprehensive way in which I have dealt with the subject, together with the inclusion of the most up-to-date material, make the book more relevant to postgraduate students of physiology, medicine and related sciences who require an introduction to the field of gastrointestinal motility and its control. I have, however, attempted to present the current concepts on the physiological mechanisms regulating motility in a way which under graduates, as well as postgraduates, will find readable, informative and, hopefully, enjoyable.
The Gastrointestinal System At A Glance
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Author : Satish Keshav
language : en
Publisher: John Wiley & Sons
Release Date : 2012-07-31
The Gastrointestinal System At A Glance written by Satish Keshav and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-07-31 with Medical categories.
This concise introduction to the gastrointestinal system encapsulates the fundamental facts and principles of this rapidly growing and changing specialty. Written by experienced clinicians and teachers, the text covers the basic concepts of both the science surrounding the gastrointestinal system and the basics of clinical practice in an accessible, lucid format. Now fully supported by a companion website at www.ataglanceseries.com/gastro containing interactive MCQs and downloadable digital flashcards, The Gastrointestinal System at a Glance is the ideal revision aid for medical and allied health students, and provides valuable insight for anyone seeking a comprehensive and concise guide to this subject area. Fully revised and updated to include further coverage of diagnostic and therapeutic endoscopy, revised liver chapters and a new chapter on embryology Now in full colour throughout Supported by a companion website containing interactive self-assessment and digital flashcards - perfect for both study and revision Provides an integrated approach to both the basic and clinical science of this core specialty