The Genetic Regulation Of Bacterial Virulence Genes

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The Genetic Regulation Of Bacterial Virulence Genes

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Author : Shaun P. Krijnen
language : en
Publisher:
Release Date : 1994

The Genetic Regulation Of Bacterial Virulence Genes written by Shaun P. Krijnen and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with categories.

Regulation Of Bacterial Virulence

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Author : Michael L. Vasil
language : en
Publisher: American Society for Microbiology Press
Release Date : 2012-12-05

Regulation Of Bacterial Virulence written by Michael L. Vasil and has been published by American Society for Microbiology Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-05 with Science categories.

A comprehensive compendium of scholarly contributions relating to bacterial virulence gene regulation. • Provides insights into global control and the switch between distinct infectious states (e.g., acute vs. chronic). • Considers key issues about the mechanisms of gene regulation relating to: surface factors, exported toxins and export mechanisms. • Reflects on how the regulation of intracellular lifestyles and the response to stress can ultimately have an impact on the outcome of an infection. • Highlights and examines some emerging regulatory mechanisms of special significance. • Serves as an ideal compendium of valuable topics for students, researchers and faculty with interests in how the mechanisms of gene regulation ultimately affect the outcome of an array of bacterial infectious diseases.

Virulence And Gene Regulation

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Author : Juan-Luis Ramos
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Virulence And Gene Regulation written by Juan-Luis Ramos and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.

Pseudomonas comprises three volumes covering the biology of pseudomonads in a wide context, including the niches they inhabit, the taxonomic relations among members of this group, the molecular biology of gene expression in different niches and under different environmental conditions, the analysis of virulence traits in plants, animals and human pathogens as well as the determinants that make some strains useful for biotechnological applications and promotion of plant growth. There has been growing interest in pseudomonads and a particular urge to understand the biology underlying the complex metabolism of these ubiquitous microbes. These bacteria are capable of colonizing a wide range of niches, including the soil, the plant rhizosphere and phylosphere, and animal tissues; more recently they have attracted attention because of their capacity to form biofilms, a characteristic with potentially important medical and environmental implications. The three volumes cover the following topics: - Taxonomy, - Genomics, - Life styles, - Cell Architecture, - Virulence, - Regulation, - Macromolecules, - Alternative Respiratory Substrates, - Catabolism and Biotransformations. Pseudomonas will be of use to all researchers working on these bacteria, particularly those studying microbiology, plant crops, pathogenesis, and chemical engineering. Advanced students in biology, medicine and agronomy will also find these three volumes a valuable reference during their studies.

Bacterial Pathogenesis Part C Identification Regulation And Function Of Virulence Factors

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Author :
language : en
Publisher: Academic Press
Release Date : 2002-12-05

Bacterial Pathogenesis Part C Identification Regulation And Function Of Virulence Factors written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-12-05 with Science categories.

The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today truly an essential publication for researchers in all fields of life sciences. Key Features * Presents alternatives to mammalian model systems * Discusses virulence and essential gene identification * Defines global gene expression

The Activities Of Bacterial Pathogens In Vivo

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Author : Harry Smith
language : en
Publisher: World Scientific
Release Date : 2001

The Activities Of Bacterial Pathogens In Vivo written by Harry Smith and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Medical categories.

Pathogenic bacteria have unique biological properties, which enable them to invade a host and cause sickness. The molecular bases of these biological properties are the determinants of pathogenicity, and the research objectives are to recognize them, identify them chemically and relate their structure to function. Most of our present knowledge comes from studies with cultures in vitro . However, there is a rising interest in bacterial behaviour in the infected host and new methods have been developed for studying it. This book describes those methods and shows how they, and a recent surge in conventional studies, are shedding light on the activities of bacterial pathogens in vivo . It discusses bacterial and host factors that operate in vivo to cause illness, showing how phenomena recognized in vitro relate to behaviour in vivo and, if evidence of relevance is not available now, indicating how it might be obtained. Sample Chapter(s). Chapter 1.1: Introduction (144 KB). Chapter 1.2: Questions about the Determinants of Bacterial Growth in Vivo (202 KB). Chapter 1.3: Questions about the Production in Vivo of Determinants of Mucosal Colonization, Penetration, Interference with Host Defence and Damage to the Host (179 KB). Chapter 1.4: Sialylation of Gonococcal Lps by Host CMP-NANA and Effect of Lactate: A Paradigm for Investigation of Behaviour in Vivo (191 KB). Chapter 1.5: Concluding Remarks (215 KB). Contents: Introduction: Questions about the Behaviour of Bacterial Pathogens In Vivo (H Smith); DNA Topology and Adaptation of Salmonella Typhimurium to an Intracellular Environment (D G Marshall et al.); New Methods for Studying Bacterial Behaviour In Vivo: The Pathogenesis of Shigella Flexneri Infection: Lessons from In Vitro and In Vivo Studies (D J Philpott et al.); Detection and Analysis of Gene Expression During Infection by In Vivo Expression Technology (D S Merrell & A Camilli); Measurement of Bacterial Gene Expression In Vivo (I Hautefort & J C D Hinton); Identification and Analysis of Bacterial Virulence Genes In Vivo (K E Unsworth & D W Holden); Salmonella Interactions with Host Cells: In Vitro to In Viv o (B B Finlay & J H Brumell); Impact of the New Methods: In Vivo Gene Expression and the Adaptive Response: From Pathogenesis to Vaccines and Antimicrobials (D M Heithoff et al.); Challenge of Investigating Biologically Relevant Functions of Virulence Factors in Bacterial Pathogens (R Moxon & C Tang); Virulence Gene Regulation Inside and Outside (V J DiRita et al.); Evidence for Operation In Vivo of Aspects of Pathogenicity Revealed by Recent Work In Vivo: Potential Use of New Methods: Quorum Sensing and the Population-Dependent Control of Virulence (P Williams et al.); Type III Secretion: A Bacterial Device for Close Combat with Cells of Their Eukaryotic Host (G R Cornelis); Evolution of Microbial Pathogens (J Morschhnuser et al.); The Immune Responses to Bacterial Antigens Encountered In Vivo at Mucosal Surfaces (G Dougan et al.). Readership: Graduate students and researchers in microbiology."

Bacterial Regulatory Networks

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Author : Alain Filloux
language : en
Publisher: Caister Academic Press Limited
Release Date : 2012

Bacterial Regulatory Networks written by Alain Filloux and has been published by Caister Academic Press Limited this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Science categories.

Regulatory networks enable bacteria to adapt to almost every environmental niche on earth. Regulation is achieved by a network of interactions among diverse types of molecules including DNA, RNA, proteins and metabolites. The primary role of regulatory networks in bacteria is to control the response to environmental changes, such as nutritional status and environmental stress. A complex organization of networks allows the organism to coordinate and integrate multiple environmental signals. Renowned authors under the expert guidance of the editor Alain A.M. Filloux, have contributed authoritative, up-to-date reviews of the current research and theories on regulatory networks in bacteria. The volume contains critical reviews written by the leading research scientists in this topical field. The authors fully explore various regulatory networks, discuss variations of common themes and provide fresh insights into bacterial regulatory mechanisms. Topics include: the sigma network in Escherichia coli, control of bacterial virulence, ECF sigma factors, quorum sensing, cyclic di-GMP, RNA-mediated regulation, the H-NS regulator, two-component regulatory systems, bacterial chemotaxis, regulation of iron homeostasis, anaerobic regulatory networks, bacterial bistable regulatory networks, and evolution of transcription factors and regulatory networks. This book is essential reading for everyone interested in gene expression and regulation in bacteria and is a recommended text for all microbiology libraries.

Listeria Monocytogenes Pathogenesis And Host Response

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Author : Howard Goldfine
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-06-24

Listeria Monocytogenes Pathogenesis And Host Response written by Howard Goldfine and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-06-24 with Science categories.

During the past twenty years Listeria monocytogenes has emerged as one of the most intensely studied bacterial pathogens. New windows are constantly being opened into the complexity of host cell biology and the interplay of the signals connecting the various cells and organs involved in the host response. This volume includes research from studies at the molecular level on the pathogenesis of Listeria monocytogenes and the response of the host to its infections.

Bacterial Pathogenesis

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Author : Brenda A. Wilson
language : en
Publisher: John Wiley & Sons
Release Date : 2020-08-11

Bacterial Pathogenesis written by Brenda A. Wilson and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-11 with Medical categories.

This highly anticipated update of the acclaimed textbook draws on the latest research to give students the knowledge and tools to explore the mechanisms by which bacterial pathogens cause infections in humans and animals. Written in an approachable and engaging style, the book uses illustrative examples and thought-provoking exercises to inspire students with the potential excitement and fun of scientific discovery. Completely revised and updated, and for the first time in stunning full-color, Bacterial Pathogenesis: A Molecular Approach, Fourth Edition, builds on the core principles and foundations of its predecessors while expanding into new concepts, key findings, and cutting-edge research, including new developments in the areas of the microbiome and CRISPR as well as the growing challenges of antimicrobial resistance. All-new detailed illustrations help students clearly understand important concepts and mechanisms of the complex interplay between bacterial pathogens and their hosts. Study questions at the end of each chapter challenge students to delve more deeply into the topics covered, and hone their skills in reading, interpreting, and analyzing data, as well as devising their own experiments. A detailed glossary defines and expands on key terms highlighted throughout the book. Written for advanced undergraduate, graduate, and professional students in microbiology, bacteriology, and pathogenesis, this text is a must-have for anyone looking for a greater understanding of virulence mechanisms across the breadth of bacterial pathogens.

Bacterial Pathogenesis

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Author : Abigail A. Salyers
language : en
Publisher: Wiley-Blackwell
Release Date : 1994

Bacterial Pathogenesis written by Abigail A. Salyers and has been published by Wiley-Blackwell this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Bacterial diseases categories.

Host defences against bacterial pathogens: defences of body surfaces; Clinical importance of understanding host defences; Preventing contactbetween host and pathogen; Skin and mucosal surfaces: the body's firstline of defence; Special defences of specific mucosal surfaces; Host defences against bacterial pathogens: defences of tissue and blood; Constitutive, nonspecific defences; Induced defences: antibodies, activated macrophages, and cytotoxic t cells; Factors that impair or improve host defences; Virulence factors that promote colonization; What is virulence?; Colonization and invasion of host surfaces; Evading complement, phagocytes, and the andibody response; Virulence factors that damage the host; Exotoxins; Hydrolytic enzymes; Bacterial products that provoke an autoimmune response; Endotoxin and other toxic bacterial cellwall components; Regulation of virulence genes; Types of regulation; Experimental approaches to investigating the host-bacterium interaction; Designing an experimental system for studing the bacterium-host interaction; Measurements of virulence; Identifying a potential virulence factor and that it is impotant for virulence; Vaccines and other approaches to modulating the immune response; Virulence factors and rational design of vaccines; Properties of good vaccines; Passive immunization; Immune stimulants other than vaccines; Antibiotics: mechanisms of action and mechanisms of bacterial resistance; Characteristics of antibiotics; Mechanisms of action of antibiotics; Resistance mechanisms; Transfer of resistance genes; Origin of antibiotic resistance genes; Paradigms of bacterium-host interactions; Diphtheria; Virulence factors; Regulation of toxin production: Treatment and prevention of diphtheria; Scarlet fever, toxic shock syndrome, and the return of severe, invasive streptococcal disease; Fluctuating fortunes of scarlet fever and TSS; Virulence factors; Treatment and prevention; Disease without colonization: food-borne toxines caused by Clostridium bolutinum, Staphylococcus aureus, and Clostridium perfringens; Botulism; Food-borne disease caused by S. aurens and C. perfrigens; Cholera (Vibrio cholerae); Pathogenesis and epidemiology of cholera; Virulence factors; Transcriptional regulation of virulence genes; Treatment and prevention; Whoopingcough (Bordetella pertussis); Whooping cough; Steps in infection; Virulence factors; Regulation of virulence genes; Treatment and prevention; Dysentery caused by Shigella species; Dysentery; Virulence factors; Organization of virulence genes; Regulation of virulence genes; Treatment and prevention; Listeria monocytogenes; Listeriosis; Virulence factors; Organization and regulation of virulence genes; Treatment and prevention; Escherichia coli gastrointestinal infections; The amazing variety of diseases caused by E. coli strains; Serotypes and virotypes; Animal and cell culture models; Virulence factors of ETEC strains; Virulence factors of EAggEC strains; Virulence factor of EPEC strains; Virulence factors of EHEC and EIEC strains; Escherichia coli urinary tract infections; Epidemiology of urinary tract infections; Virulence factors of Uropathogenic E. coli strains; Organization and regulation of virulence genes; Treatment and prevention; Yersinia infections; Pathogenic Yersinia species; Virulence mechanisms; Regulation of virulence genes; Treatment and prevention; Salmonella infections; Salmonella species and serogroups; Diseases caused by species and serotypes of Salmonella; Virulence factors; Regulation of virulence genes; Treatment and prevention; Neisseria gonorrhoeae; Gonorrhea; Virulence factors; Continuing search for a vaccine against gonorrhea; Pseudomonas aeruginosa; The quintessential opportunist; Virulence factors; Future Challenges; Gastric and duodenal ulcers: an infections disease; Revolution in gastroentorology; Virulence factors; Treatment and prevention; Pseudomembranous colitis; Pseudomembranous colitis: a disease caused by antibiotics; Virulence factrs; Treatment and prevention; Lyme disease and syphilis; Lyma disease; Virulence factors; Syphilis and lyme disease: two spirochetal diseases with a similar pathology; Treatment and prevention; Legionnaire's disease; The dark side of modern comforts: air conditioning turns ugly; Virulence factors; Treatment and prevention; Tuberculosis; A disease of the past returns to haunt the future; Spread and progression of TB; M. tuberculosis and its unusual cell wall; Emergenceand treatment of drug-resistant TB; Diagnosis of TB; Virulence factors; Immunity to TB; Streptococcus pneumoniae; Streptococcus pneumoniae: an inflammatory subject; Charateristics of S. pneumoniae; Virulence factors; Treatment and prevention; Streptococcal sore throat, rheumatic fever, and glomerulonephritis; The unsolved riddle of rheumatic fever and glomerulonephritis; Virulence factors; Treatment and prevention; Cell surface structure of bacteria; Phylogenetic diversity of pathogenic bacteria; Nucleic acid-based detection systems; Answers to end-of-chapter questions.

Molecular Mechanisms Of Bacterial Virulence

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Author : C.I. Kado
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Molecular Mechanisms Of Bacterial Virulence written by C.I. Kado and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.

The growing body of information on bacteria pathogenic for humans, mammals and plants generated within the past ten years has shown the interesting conservation of newly identified genes that playa direct role in the pathogenic mechanism. In addition to these genes, there are also genes that confer host specificities and other traits important in pathogenesis on these pathogens. In this volume, we have organized the subject areas to best fit the concept on the way bacterial pathogens recognize, interact and invade the host, on the regulation of genes involved in virulence, on the genes involved in the elaboration of toxins and other pathogenic components such as iron sequestering proteins, and on the mechanisms of circumventing the host defense systems. These areas are divided into Sections. Section I covers the first step when the pathogen seeks its host, and Sections II through VI cover subsequent steps leading to pathogenesis while avoiding host defenses. We conclude this work with a chapter summarizing information on examples of virulence mechanisms that are highly conserved.