The Hygiene Hypothesis And Darwinian Medicine
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The Hygiene Hypothesis And Darwinian Medicine
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Author : Graham A.W. Rook
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-12-24
The Hygiene Hypothesis And Darwinian Medicine written by Graham A.W. Rook and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12-24 with Medical categories.
Man has moved rapidly from the hunter-gatherer environment to the living conditions of industrialised countries. The hygiene hypothesis suggests that the resulting reduced exposure to micro-organisms has led to disordered regulation of the immune system, and hence to increases in certain chronic inflammatory disorders, like allergic disorders, autoimmunity, inflammatory bowel disease, atherosclerosis, depression, some cancers and perhaps Alzheimer and Parkinson. This book discusses the evidence for and against in the context of Darwinian medicine, which uses knowledge of evolution to cast light on human diseases. The approach is interdisciplinary, looking at man’s microbiological history, at the biology of the effects of microorganisms on the immune system, and at the implications for chronic inflammatory disorders in multiple organ systems. Finally, the authors describe progress in the exploitation of microorganisms or their components as novel prophylactics and treatments.
Body By Darwin
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Author : Jeremy Taylor
language : en
Publisher: University of Chicago Press
Release Date : 2015-10-22
Body By Darwin written by Jeremy Taylor and has been published by University of Chicago Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-22 with Medical categories.
This exploration of cutting-edge evolutionary medicine and how our body’s performance is shaped by its past “covers fascinating territory” (Publishers Weekly). We think of medical science and doctors as focused on treating conditions—whether it’s a cough or an aching back. But the sicknesses and complaints that cause us to seek medical attention actually have deeper origins than the superficial germs and behaviors we regularly fault. In fact, as Jeremy Taylor shows in Body by Darwin, we can trace the roots of many medical conditions through our evolutionary history, revealing what has made us susceptible to certain illnesses and ailments over time and how we can use that knowledge to help treat or prevent problems in the future. In Body by Darwin, Taylor examines the evolutionary origins of some of our most common and serious health issues. To begin, he looks at the hygiene hypothesis, which argues that our obsession with anti-bacterial cleanliness, particularly at a young age, may be making us more vulnerable to autoimmune and allergic diseases. He also discusses diseases of the eye, the medical consequences of bipedalism as they relate to all those aches and pains in our backs and knees, the rise of Alzheimer’s disease, and how cancers become so malignant that they kill us despite the toxic chemotherapy we throw at them. Taylor explains why it helps to think about heart disease in relation to the demands of an ever-growing, dense, muscular pump that requires increasing amounts of nutrients, and he discusses how walking upright and giving birth to ever larger babies led to a problematic compromise in the design of the female spine and pelvis. Throughout, he not only explores the impact of evolution on human form and function, but integrates science with stories from actual patients and doctors, closely examining the implications for our health. “Seven vivid true stories dramatically describing patients and their doctors discovering evolutionary explanations for diseases. More than just the perfect book club book, it advances the field of evolutionary medicine.” —Randolph M. Nesse, coauthor of Why We Get Sick
Evolution Biodiversity And A Reassessment Of The Hygiene Hypothesis
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Author : Graham A. W. Rook
language : en
Publisher: Springer
Release Date : 2023-03-26
Evolution Biodiversity And A Reassessment Of The Hygiene Hypothesis written by Graham A. W. Rook and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-26 with Medical categories.
This edited collection of 12 chapters by research workers from a wide range of disciplines resolves the confusion that currently surrounds the “hygiene hypothesis” by considering the human need for exposure to microorganisms from an evolutionary point of view. The book explains why we evolved a requirement for exposure to microbiota from our mothers, from other people, and from the natural environment. It also explains the physiological roles of these exposures, what goes wrong when the exposures are distorted and how human lifestyles and activities, including degradation of the natural environment, are leading to this distortion. Particular attention is given to the range of pathologies associated with inappropriate microbial exposures and inappropriate colonization, including immunoregulatory problems such as allergies and autoimmunity, metabolic problems such as obesity and diabetes, and problems of central nervous system function and neurodegeneration. This book is of profound relevance to most medical disciplines, but also to those concerned with preserving the natural environment and with developing healthier urbanisation.
Body By Darwin
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Author : Jeremy Taylor
language : en
Publisher: University of Chicago Press
Release Date : 2015-10-22
Body By Darwin written by Jeremy Taylor and has been published by University of Chicago Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-22 with Medical categories.
We think of medical science and doctors as focused on treating conditions—whether it’s a cough or an aching back. But the sicknesses and complaints that cause us to seek medical attention actually have deeper origins than the superficial germs and behaviors we regularly fault. In fact, as Jeremy Taylor shows in Body by Darwin, we can trace the roots of many medical conditions through our evolutionary history, revealing what has made us susceptible to certain illnesses and ailments over time and how we can use that knowledge to help us treat or prevent problems in the future. In Body by Darwin, Taylor examines the evolutionary origins of some of our most common and serious health issues. To begin, he looks at the hygiene hypothesis, which argues that our obsession with anti-bacterial cleanliness, particularly at a young age, may be making us more vulnerable to autoimmune and allergic diseases. He also discusses diseases of the eye, the medical consequences of bipedalism as they relate to all those aches and pains in our backs and knees, the rise of Alzheimer’s disease, and how cancers become so malignant that they kill us despite the toxic chemotherapy we throw at them. Taylor explains why it helps to think about heart disease in relation to the demands of an ever-growing, dense, muscular pump that requires increasing amounts of nutrients, and he discusses how walking upright and giving birth to ever larger babies led to a problematic compromise in the design of the female spine and pelvis. Throughout, he not only explores the impact of evolution on human form and function, but he integrates science with stories from actual patients and doctors, closely examining the implications for our health. As Taylor shows, evolutionary medicine allows us think about the human body and its adaptations in a completely new and productive way. By exploring how our body’s performance is shaped by its past, Body by Darwin draws powerful connections between our ancient human history and the future of potential medical advances that can harness this knowledge.
An Epidemic Of Absence
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Author : Moises Velasquez-Manoff
language : en
Publisher: Simon and Schuster
Release Date : 2013-09-17
An Epidemic Of Absence written by Moises Velasquez-Manoff and has been published by Simon and Schuster this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-09-17 with Biography & Autobiography categories.
A controversial, revisionist approach to autoimmune and allergic disorders considers the perspective that the human immune system has been disabled by twentieth-century hygiene and medical practices.
Principles Of Evolutionary Medicine
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Author : Peter D. Gluckman
language : en
Publisher: Oxford University Press
Release Date : 2016
Principles Of Evolutionary Medicine written by Peter D. Gluckman and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with Science categories.
This is the first integrated and comprehensive textbook to explain the principles of evolutionary biology from a medical perspective and to focus on how medicine and public health might utilise evolutionary biology.
Evolution In Health And Disease
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Author : Stephen C. Stearns
language : en
Publisher: Oxford University Press
Release Date : 2008
Evolution In Health And Disease written by Stephen C. Stearns and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Medical categories.
This work explores and analyses the ways in which our ancient genes contend with, and influence, modern human life. It offers coverage of the points of contact between evolutionary biology and medical science.
Why We Get Sick
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Author : Randolph M. Nesse, MD
language : en
Publisher: Vintage
Release Date : 2012-02-08
Why We Get Sick written by Randolph M. Nesse, MD and has been published by Vintage this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-08 with Health & Fitness categories.
The next time you get sick, consider this before picking up the aspirin: your body may be doing exactly what it's supposed to. In this ground-breaking book, two pioneers of the science of Darwinian medicine argue that illness as well as the factors that predispose us toward it are subject to the same laws of natural selection that otherwise make our bodies such miracles of design. Among the concerns they raise: When may a fever be beneficial? Why do pregnant women get morning sickness? How do certain viruses "manipulate" their hosts into infecting others? What evolutionary factors may be responsible for depression and panic disorder? Deftly summarizing research on disorders ranging from allergies to Alzheimer's, and form cancer to Huntington's chorea, Why We Get Sick, answers these questions and more. The result is a book that will revolutionize our attitudes toward illness and will intrigue and instruct lay person and medical practitioners alike.
The Oxford Handbook Of Evolutionary Medicine
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Author : Martin Brüne
language : en
Publisher: Oxford University Press
Release Date : 2019-01-31
The Oxford Handbook Of Evolutionary Medicine written by Martin Brüne and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-31 with Medical categories.
Medicine is grounded in the natural sciences, among which biology stands out with regard to the understanding of human physiology and conditions that cause dysfunction. Ironically though, evolutionary biology is a relatively disregarded field. One reason for this omission is that evolution is deemed a slow process. Indeed, macroanatomical features of our species have changed very little in the last 300,000 years. A more detailed look, however, reveals that novel ecological contingencies, partly in relation to cultural evolution, have brought about subtle changes pertaining to metabolism and immunology, including adaptations to dietary innovations, as well as adaptations to the exposure to novel pathogens. Rapid pathogen evolution and evolution of cancer cells cause major problems for the immune system to find adequate responses. In addition, many adaptations to past ecologies have turned into risk factors for somatic disease and psychological disorder in our modern worlds (i.e. mismatch), among which epidemics of autoimmune diseases, cardiovascular diseases, diabetes and obesity, as well as several forms of cancer stand out. In addition, depression, anxiety and other psychiatric conditions add to the list. The Oxford Handbook of Evolutionary Medicine is a compilation of cutting edge insights into the evolutionary history of ourselves as a species, and how and why our evolved design may convey vulnerability to disease. Written in a classic textbook style emphasising physiology and pathophysiology of all major organ systems, the Oxford Handbook of Evolutionary Medicine will be valuable for students as well as scholars in the fields of medicine, biology, anthropology and psychology.
Human Evolution Beyond Biology And Culture
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Author : Jeroen C. J. M. van den Bergh
language : en
Publisher: Cambridge University Press
Release Date : 2018-10-18
Human Evolution Beyond Biology And Culture written by Jeroen C. J. M. van den Bergh and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-18 with Nature categories.
A complete account of evolutionary thought in the social, environmental and policy sciences, creating bridges with biology.