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The Immunoglobulin Receptors And Their Physiological And Pathological Roles In Immunity

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The Immunoglobulin Receptors And Their Physiological And Pathological Roles In Immunity

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Author : Jan G.J. Winkel
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-02-02

The Immunoglobulin Receptors And Their Physiological And Pathological Roles In Immunity written by Jan G.J. Winkel and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-02 with Medical categories.

Antibodies are crucial to the fine specificity of the immune system. An effective functioning of these molecules requires interaction with immune cells. Receptors for antibodies, Fc receptors, provide this critical link between the humoral and cellular branches of the immune system. This book presents a comprehensive overview of the different Fc receptors currently recognized. The first part of the book contains state-of-the-art overviews on the biological role of FcR. The latest information on FcR heterogeneity, FcR physiology, FcR-ligand recognition, their crucial coordinating role in immunity, interactions with other immunoreceptors, and the role of FcR in immunoglobulin transport and catabolism are discussed. The clinical importance of FcR is developed in the second part of the book. The well-recognized roles of FcR in allergy, inflammation, infectious diseases, autoimmune disorders, and immunotherapeutic importance are reviewed. The information in this book is easily accessible and should be helpful for researchers and clinical specialists as a convenient overview of the field, as well as a comprehensive introduction for students starting in this area of research.

Aids Pathogenesis

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Author : H. Schuitemaker
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-17

Aids Pathogenesis written by H. Schuitemaker and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-17 with Medical categories.

Infection with the human immunodeficiency virus is characterized by the destruction of the host immune system as also reflected by a progressive loss of CD4-positive T-cells. This finally results in the host's incapacity to deal with opportunistic infections and the immune surveillance of tumors, a clinical status known as the Acquired Immunodeficiency Syndrome (AIDS). The book AIDS Pathogenesis provides the reader with a complete overview of the clinical course of HIV-1 infection. It describes the clinical aspects of primary infection, the different clinical outcomes of HIV-1 infection, and strategies for anti-viral treatment. In addition, more fundamental aspects of HIV-1 infection are reviewed. These include the biology of the virus and the novel insights in AIDS pathogenesis. Not only is the significance of an HIV-specific cellular and humoral immune response discussed, but also the possible incapacity of the adult human host to deal with T-cell destruction. Finally, the book discusses the currently used laboratory markers that allow for monitoring of the clinical course of infection.

Endocrine Autoimmunity And Associated Conditions

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Author : A.P. Weetman
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Endocrine Autoimmunity And Associated Conditions written by A.P. Weetman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.

Autoimmunity is the most common cause of endocrine disorders. This volume provides an up-to-date summary of recent advances in this important field. In addition, it describes developments in our understanding of conditions such as vitiligo and pernicious anaemia which are frequently associated with autoimmune endocrinopathies. There is a detailed review of animal models of endocrine disease which have contributed greatly to current knowledge. Furthermore, the aetiology, pathogenesis and treatment of the clinical disorders are discussed in depth. The book will be of interest to anyone working in the areas of endocrinology and immunology.

The Gene Knockout Factsbook Two Volume Set

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Author :
language : en
Publisher: Academic Press
Release Date : 1998-10-26

The Gene Knockout Factsbook Two Volume Set written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-10-26 with Science categories.

The FactsBooks Series has established itself as the best source of easily-accessible and accurate facts about protein groups. Described as "a growing series of excellent manuals" by Molecular Medicine Today, and "essential works of reference" by Trends in Biochemical Sciences, the FactsBooks have become the most popular comprehensive data resources available. Using an easy-to-follow format and drawing from meticulous research, the Factsbooks will keep you up-to-date with the latest advances in structure, amino acid sequences, physicochemical properties, and biological activity. The Gene Knockout FactsBook contains entries, grouped into subject disciplines, covering immunology, neurobiology, development, cancer, and other knockouts. It describes more than 600 gene knockouts described and listed in alphabetical order for easy reference.Key Features* Entries provide information on:* general description of the protein and its function* gene symbol and database accession number* knockout construct* mouse phenotype* key references

The Immune Response

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Author : Tak W. Mak
language : en
Publisher: Academic Press
Release Date : 2005-11-11

The Immune Response written by Tak W. Mak and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-11-11 with Medical categories.

The Immune Response is a unique reference work covering the basic and clinical principles of immunology in a modern and comprehensive fashion. Written in an engaging conversational style, the book conveys the broad scope and fascinating appeal of immunology. The book is beautifully illustrated with superb figures as well as many full color plates. This extraordinary work will be an invaluable resource for lecturers and graduate students in immunology, as well as a vital reference for research scientists and clinicians studying related areas in the life and medical sciences. - Current and thorough 30 chapter reference reviewed by luminaries in the field - Unique 'single voice' ensures consistency of definitions and concepts - Comprehensive and elegant illustrations bring key concepts to life - Provides historical context to allow fuller understanding of key issues - Introductory chapters 1-4 serve as an 'Immunology Primer' before topics are discussed in more detail

Labs On Chip

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Author : Eugenio Iannone
language : en
Publisher: CRC Press
Release Date : 2018-09-03

Labs On Chip written by Eugenio Iannone and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-03 with Medical categories.

Labs on Chip: Principles, Design and Technology provides a complete reference for the complex field of labs on chip in biotechnology. Merging three main areas— fluid dynamics, monolithic micro- and nanotechnology, and out-of-equilibrium biochemistry—this text integrates coverage of technology issues with strong theoretical explanations of design techniques. Analyzing each subject from basic principles to relevant applications, this book: Describes the biochemical elements required to work on labs on chip Discusses fabrication, microfluidic, and electronic and optical detection techniques Addresses planar technologies, polymer microfabrication, and process scalability to huge volumes Presents a global view of current lab-on-chip research and development Devotes an entire chapter to labs on chip for genetics Summarizing in one source the different technical competencies required, Labs on Chip: Principles, Design and Technology offers valuable guidance for the lab-on-chip design decision-making process, while exploring essential elements of labs on chip useful both to the professional who wants to approach a new field and to the specialist who wants to gain a broader perspective.

Immunoreceptor Tyrosine Based Inhibition Motifs

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Author : Marc Daeron
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Immunoreceptor Tyrosine Based Inhibition Motifs written by Marc Daeron and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.

Novel molecular motifs named Immunoreceptor Tyrosine-based Inhibition Motifs (ITIMs) have recently been recognized in the intracytoplasmic domains of a still-increasing number of receptors which control cell activation and proliferation. Research on ITIM-bearing molecules has developed exponentially during the last three years, generating new concepts with important consequences in basic research and with exciting potential clinical applications. The present volume contains 15 reviews written by authors who all made significant contributions to the identification of ITIM-bearing molecules and the study of their biological properties. It constitutes the first synthesis ever published that is specifically devoted to this emerging topic.