The Implicit Genome
DOWNLOAD
Download The Implicit Genome PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get The Implicit Genome book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
The Implicit Genome
DOWNLOAD
Author : Lynn Helena Caporale
language : en
Publisher:
Release Date : 2023
The Implicit Genome written by Lynn Helena Caporale and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023 with Evolutionary genetics categories.
Discusses three interconnected themes: information can be implied, rather than explicit, in a genome; information can lead to focused and/or regulated changes in nucleotide sequences; and information that affects the probability of distinct classes of mutation has implications for evolutionary theory.
The Topological Model Of Genome And Evolution
DOWNLOAD
Author : Pradeep Chhaya
language : en
Publisher: Springer Nature
Release Date : 2023-09-19
The Topological Model Of Genome And Evolution written by Pradeep Chhaya and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-19 with Science categories.
This book deals with the missing link in the domain of functional genomics viz. genomic architecture. It begins with a deconstruction of the Darwinian paradigm using the proposed model of modified involuted manifolds. It recasts the process of natural selection as a process of information transfer. Using a topological model, this book outlines a new genomic architecture. The key argument for this proposed model is that some such structuralism has always been implicit in genomics. The proposed model fits very well with the known genomic characteristics and allows to separate the regulatory genome from the transcriptive genomes. The model is capable of discerning modular architecture of genomes with different genomic functionalities existing in hierarchical relationships and demonstrates that genomes act as units of selection and as the environment for the individual genes which act as competing species. Towards the end, the book also examines the role of genomic evolution in cancer and the principles of natural selection and evolution of the genotype. The regulatory genome is also discussed, with an emphasis on its evolution and natural selection. It is a valuable source for researchers working in functional genomics, mathematical modeling in biology and evolutionary genomics.
The Goldilocks Genome
DOWNLOAD
Author : Elizabeth Reed Aden
language : en
Publisher: Simon and Schuster
Release Date : 2024-05-21
The Goldilocks Genome written by Elizabeth Reed Aden and has been published by Simon and Schuster this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-05-21 with Fiction categories.
When San Francisco–based FDA epidemiologist Dr. Carrie Hediger uncovers a rash of unexplained deaths while investigating the suspiciously convenient death of her best friend, she becomes determined to find answers—even if it leads her to a murderer, and even if confronting authority, using her wiles, and bending the rules to get justice risks her future in the FDA. To unravel the puzzle, Carrie assembles a team: some talented post-doctoral fellows, a quirky pharmacologist, an unctuous chemist, and a skeptical FBI agent that she can’t help her attraction for. Together, they follow the data through the twists and turns, eventually uncovering that the Goldilocks effect in prescription drugs—the premise that people are inclined to seek “just the right amount” of something—is central to understanding these mysterious deaths. Through the twists and turns, Carrie and her team enter a race to uncover the truth . . . and catch a killer. Grounded in real data analysis techniques, real science and pharmacology, and actual current psychiatric practices, The Goldilocks Genome is simultaneously a taut, race-against-time thriller and a condemnation of the psychiatric industry’s failure to implement genetic-based “personalized medicine”—a problem that persists to this day.
The Dynamic Genome
DOWNLOAD
Author : Antonio Fontdevila
language : en
Publisher: Oxford University Press
Release Date : 2011-06-02
The Dynamic Genome written by Antonio Fontdevila and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-06-02 with Medical categories.
These novelties, among others, are examined in this book in relation to their general significance for evolution, emphasising their human relevance.
The Material Gene
DOWNLOAD
Author : Kelly E. Happe
language : en
Publisher: NYU Press
Release Date : 2013-05-06
The Material Gene written by Kelly E. Happe and has been published by NYU Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-06 with Social Science categories.
In 2000, the National Human Genome Research Institute announced the completion of a “draft” of the human genome, the sequence information of nearly all 3 billion base pairs of DNA. In the wake of this major scientific accomplishment, the focus on the genetic basis of disease has sparked many controversies as questions are raised about radical preventative therapies, the role of race in research, and the environmental origins of illness. In The Material Gene, Kelly Happe explores the cultural and social dimensions of our understandings of genomics, using this emerging field to examine the physical manifestation of social relations. Situating contemporary genomics medicine and public health within a wider history of eugenics, Happe examines how the relationship between heredity and dominant social and economic interests has shifted along with transformations in gender and racial politics, social movement, and political economy. Happe demonstrates that genomics is a type of social knowledge, relying on cultural values to attach meaning to the body. The Material Gene situates contemporary genomics within a history of genetics research yet is attentive to the new ways in which knowledge claims about heredity, race, and gender emerge and are articulated to present-day social and political agendas. Kelly E. Happe is assistant professor of communication studies and women’s studies at the University of Georgia.
Tandem Repeat Polymorphisms
DOWNLOAD
Author : Anthony J. Hannan
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-07-30
Tandem Repeat Polymorphisms written by Anthony J. Hannan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-07-30 with Medical categories.
This book addresses the role of tandem repeat polymorphisms (TRPs) in genetic plasticity, evolution, development, biological processes, neural diversity, brain function, dysfunction and disease. There are hundreds of thousands of unique tandem repeats in the human genome and their polymorphic distributions have the potential to greatly influence functional diversity and disease susceptibility. Recent discoveries in this expanding field are critically reviewed and discussed in a range of subsequent chapters, with a focus on the role of TRPs and their various gene products in evolution, development, diverse molecular and cellular processes, brain function and disease.
What S In Your Genome
DOWNLOAD
Author : Laurence A. Moran
language : en
Publisher: University of Toronto Press
Release Date : 2023-05-16
What S In Your Genome written by Laurence A. Moran and has been published by University of Toronto Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-16 with Science categories.
What’s in Your Genome? describes the functional regions of the human genome, the evidence that 90% of it is junk DNA, and the reasons this evidence has not been widely accepted by the popular press and much of the scientific community. The human genome contains about 25,000 protein-coding and noncoding genes and many other functional elements, such as origins of replication, regulatory elements, and centromeres. Functional elements occupy only about 10 percent of the more than three billion base pairs in the human genome. Much of the rest is composed of ancient fragments of broken genes, transposons, and viruses. Almost all of this is thought to be junk DNA, based on evidence that dates back fifty years. This conclusion is controversial. What’s in Your Genome? describes the arguments on both sides of the debate and attempts to explain the reasoning behind those different points of view. The book corrects a number of false narratives that have arisen in recent years and examines how they have affected the debate over junk DNA. In addition, Laurence A. Moran focuses on scientific misconceptions and misinformation and on how the junk DNA controversy has been incorrectly portrayed in both the scientific literature and the popular press. Tracing the earliest indications of junk DNA back to the 1960s, the book explains the success of nearly neutral theory and the importance of random genetic drift, which gave rise to the view that evolution produces sloppy genomes full of junk DNA. What’s in Your Genome? aims to offer the most accurate and current account of the human genome.
Computational Genomic Signatures
DOWNLOAD
Author : Ozkan Ufuk Nalbantoglu
language : en
Publisher: Springer Nature
Release Date : 2022-06-01
Computational Genomic Signatures written by Ozkan Ufuk Nalbantoglu and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-01 with Technology & Engineering categories.
Recent advances in development of sequencing technology has resulted in a deluge of genomic data. In order to make sense of this data, there is an urgent need for algorithms for data processing and quantitative reasoning. An emerging in silico approach, called computational genomic signatures, addresses this need by representing global species-specific features of genomes using simple mathematical models. This text introduces the general concept of computational genomic signatures, and it reviews some of the DNA sequence models which can be used as computational genomic signatures. The text takes the position that a practical computational genomic signature consists of both a model and a measure for computing the distance or similarity between models. Therefore, a discussion of sequence similarity/distance measurement in the context of computational genomic signatures is presented. The remainder of the text covers various applications of computational genomic signatures in the areas of metagenomics, phylogenetics and the detection of horizontal gene transfer. Table of Contents: Genome Signatures, Definition and Background / Other Computational Characterizations as Genome Signatures / Measuring Distance of Biological Sequences Using Genome Signatures / Applications: Phylogeny Construction / Applications: Metagenomics / Applications: Horizontal DNA Transfer Detection
Genome Informatics 2009 Genome Informatics Series Vol 23 Proceedings Of The 20th International Conference
DOWNLOAD
Author : Yasubumi Sakakibara
language : en
Publisher: Imperial College Press
Release Date : 2009-10-23
Genome Informatics 2009 Genome Informatics Series Vol 23 Proceedings Of The 20th International Conference written by Yasubumi Sakakibara and has been published by Imperial College Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-10-23 with Science categories.
This volume contains papers presented at the 20th International Conference on Genome Informatics (GIW 2009) held at the Pacifico Yokohama, Japan from December 14 to 16, 2009. The GIW Series provides an international forum for the presentation and discussion of original research papers on all aspects of bioinformatics, computational biology and systems biology. Its scope includes biological sequence analysis, protein structure prediction, genetic regulatory networks, bioinformatic algorithms, comparative genomics, and biomolecular data integration and analysis. Boasting a history of 20 years, GIW is the longest-running international bioinformatics conference.A total of 18 contributed papers were selected for presentation at GIW 2009 and for inclusion in this book. In addition, this book contains abstracts from the five invited speakers: Sean Eddy (HHMI's Janelia Farm, USA), Minoru Kanehisa (Kyoto University, Japan), Sang Yup Lee (KAIST, Korea), Hideyuki Okano (Keio University, Japan) and Mark Ragan (University of Queensland, Australia)./a
Genome Informatics 2009
DOWNLOAD
Author : Shinichi Morishita
language : en
Publisher: World Scientific
Release Date : 2009
Genome Informatics 2009 written by Shinichi Morishita and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Bioinformatics categories.
This volume contains papers presented at the 20th International Conference on Genome Informatics (GIW 2009) held at the Pacifico Yokohama, Japan from December 14 to 16, 2009. The GIW Series provides an international forum for the presentation and discussion of original research papers on all aspects of bioinformatics, computational biology and systems biology. Its scope includes biological sequence analysis, protein structure prediction, genetic regulatory networks, bioinformatic algorithms, comparative genomics, and biomolecular data integration and analysis. Boasting a history of 20 years, GIW is the longest-running international bioinformatics conference. A total of 18 contributed papers were selected for presentation at GIW 2009 and for inclusion in this book. In addition, this book contains abstracts from the five invited speakers: Sean Eddy (HHMI's Janelia Farm, USA), Minoru Kanehisa (Kyoto University, Japan), Sang Yup Lee (KAIST, Korea), Hideyuki Okano (Keio University, Japan) and Mark Ragan (University of Queensland, Australia).