The Neurobiology Of Dopamine Systems
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The Neurobiology Of Dopamine Systems
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Author : Northern Neurobiology Group (Great Britain). Symposium
language : en
Publisher: Manchester University Press
Release Date : 1986
The Neurobiology Of Dopamine Systems written by Northern Neurobiology Group (Great Britain). Symposium and has been published by Manchester University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Dopamine categories.
Dopamine
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Author :
language : en
Publisher: Elsevier
Release Date : 2014-06-23
Dopamine written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-06-23 with Science categories.
Progress in Brain Research is a well-established international series examining major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This volume, concentrates on state-of-the-art of dopamine research: from basic science to clinical applications. It covers topics including thalamostriatal synapses as a substrate for dopamine action; the multilingual nature of dopamine neurons; ethanol-mechanisms along the mesolimbic dopamine system, and much more.Progress in Brain Research is the most acclaimed and accomplished series in neuroscience, firmly established as an extensive documentation of the advances in contemporary brain research. The volumes, some of which are derived from important international symposia, contain authoritative reviews and original articles by invited specialists. The rigorous editing of the volumes assures that they will appeal to all laboratory and clinical brain research workers in the various disciplines: neuroanatomy, neurophysiology, neuropharmacology, neuroendocrinology, neuropathology, basic neurology, biological psychiatry, and the behavioral sciences. The most acclaimed and accomplished series in neuroscience This volume looks at dopamine research in the light of the newest scholarly discoveries and insights
Dopaminergic Systems And Their Regulation
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Author : G.N. Woodruff
language : en
Publisher: Springer
Release Date : 2016-01-15
Dopaminergic Systems And Their Regulation written by G.N. Woodruff and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-15 with Medical categories.
Neurobiology Of Central D1 Dopamine Receptors
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Author : George Breese
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09
Neurobiology Of Central D1 Dopamine Receptors written by George Breese and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Medical categories.
Our understanding of the functional mechanisms relating dopamine activity to normal and abnormal behavior has been turned "upside-down" by the recent developments described in the chapters of this volume. Heretofore, it was generally agreed that all of the pharmacological and behavioral properties ascribed to dopamine systems were mediated via activation or inhibition of the subtype of dopamine receptors termed D2. The properties of these receptors were first characterized in 1975 following their identification by receptor binding techniques utilizing 3H-butyrophenones, potent antipsychotic drugs, used in the treatment of schizophrenia. Although another subtype of dopamine receptor had already been identified a few years earlier, now termed the Dl receptor, its functional properties were unknow- other than the fact that it was associated with the activation of the enzyme adenylate cyclase. Our absence of knowledge of the behavioral functions of this receptor stemmed primarily from the lack of selective agonist and antagonists for DI receptors - drugs which did not also interact with D2 receptors. Selective agents for D2 receptors did exist and hence the behavioral roles of D2 receptors were easily ascribed. The work described in this text is primarily stimulated by the development of two selective Dl receptor drugs - the antagonist SCH 23390 and the agonist SKF 38393. The studies described herein clearly show that D1 receptors do indeed have many behavioral functions, on the surface often similar to those responses mediated by D2 receptors.
The Dopaminergic System
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Author : Béla Halász
language : en
Publisher: Springer Verlag
Release Date : 1985-01-01
The Dopaminergic System written by Béla Halász and has been published by Springer Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985-01-01 with Dopamine categories.
The Role Of Brain Dopamine
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Author :
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
The Role Of Brain Dopamine written by and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
As in other volumes in the series, this newest volume conveys up-to-date knowledge in a clear and straightforward manner. It begins with a survey of the neurobiological functions of the brain, with the emphasis on Parkinson's disease. This is followed by a presentation of the role of dopamine in the regulation of human anterior pituitary function. The final two chapters concentrate on the dopamine receptors: first, the binding sites are characterized and the biochemical and physiological consequences of dopamine-receptor stimulation are discussed and, finally, there is a report on the topology of a dopamine-receptor model that can account comprehensively for agonists and antagonists.
Neurobiology Of Addiction
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Author : George F. Koob
language : en
Publisher: Elsevier
Release Date : 2005-11-11
Neurobiology Of Addiction written by George F. Koob and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-11-11 with Psychology categories.
Neurobiology of Addiction is conceived as a current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction over the past 50 years. The book includes a scholarly introduction, thorough descriptions of animal models of addiction, and separate chapters on the neurobiological mechanisms of addiction for psychostimulants, opioids, alcohol, nicotine and cannabinoids. Key information is provided about the history, sources, and pharmacokinetics and psychopathology of addiction of each drug class, as well as the behavioral and neurobiological mechanism of action for each drug class at the molecular, cellular and neurocircuitry level of analysis. A chapter on neuroimaging and drug addiction provides a synthesis of exciting new data from neuroimaging in human addicts — a unique perspective unavailable from animal studies. The final chapters explore theories of addiction at the neurobiological and neuroadaptational level both from a historical and integrative perspective. The book incorporates diverse finding with an emphasis on integration and synthesis rather than discrepancies or differences in the literature. · Presents a unique perspective on addiction that emphasizes molecular, cellular and neurocircuitry changes in the transition to addiction · Synthesizes diverse findings on the neurobiology of addiction to provide a heuristic framework for future work · Features extensive documentation through numerous original figures and tables that that will be useful for understanding and teaching
Development And Engineering Of Dopamine Neurons
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Author : Jeroen Pasterkamp
language : en
Publisher: Springer
Release Date : 2009-06-04
Development And Engineering Of Dopamine Neurons written by Jeroen Pasterkamp and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-06-04 with Medical categories.
Theneurotransmitter dopamine has just celebrated its 50thbirthday. The discovery of dopamine as a neuronal entity in the late 1950s and the notion that it serves in neurotransmission has been a milestone in the field of neuroscience research. This milestone marked the beginning of an era that explored the brain as an integrated collection of neuronal systems that one could distinguish on basis of neurotransm- ter identities, and importantly, in which one started to be able to pinpoint the seat of brain disease. The mesodiencephalic dopaminergic (mdDA) system, previously designated as midbraindopaminergic system, has received much attention since its discovery. The initial identification of dopamine as a neurotransmitter in the central nervous system (CNS) and its relevance to psychiatric and neurological disorders have stimulated a plethora of neurochemical, pharmacological and genetic studies into the function of dopamine neurons and theirprojections. In the last decade, studies on gene expression and development have further increased the knowledge of this neuronal population and have unmasked a new level of complexity. The start of the molecular dissection of the mdDA system has been marked by the cloning and characterization ofNurrl and Pitx3. These transcription factors were shown to have a critical function during mdDA development. These initial studies have been followed by the identification of many other proteins, which have a crucial function in the creation of a dopamine neuron permissive region, induction of precursors, induction of terminaldifferent- tion and finally maintenance of the mdDA neuronal pool.
Neurobiology Of Sensation And Reward
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Author : Jay A. Gottfried
language : en
Publisher: CRC Press
Release Date : 2011-03-28
Neurobiology Of Sensation And Reward written by Jay A. Gottfried and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-03-28 with Medical categories.
Synthesizing coverage of sensation and reward into a comprehensive systems overview, Neurobiology of Sensation and Reward presents a cutting-edge and multidisciplinary approach to the interplay of sensory and reward processing in the brain. While over the past 70 years these areas have drifted apart, this book makes a case for reuniting sensation a
Neurobiological Circuit Function And Computation Of The Serotonergic And Related Systems
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Author : KongFatt Wong-Lin
language : en
Publisher: Frontiers Media SA
Release Date : 2015-02-24
Neurobiological Circuit Function And Computation Of The Serotonergic And Related Systems written by KongFatt Wong-Lin and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-02-24 with Dopamine categories.
Serotonin is one of the oldest neurotransmitters in evolutionary terms, and the serotonergic system is complex and multifaceted. Serotonin-producing neurons in the raphe nuclei provide serotonin innervations throughout various parts of the brain, modulating cellular excitability and network properties of targeted brain areas, and regulating mood, cognition and behavior. Dysfunctions of the serotonergic system are implicated in neuropsychiatric disorders including depression, schizophrenia, and drug abuse. Although the system has been studied for many years, an integrative account of its functions and computational principles remains elusive. This is partly attributed to the high variability and heterogeneity in terms of neuronal properties and receptor types, and its extensive connections with other brain regions. This Frontiers Research Topic e-book is a collection of recent experimental and computational work and approaches at multiple scales that provide the latest information regarding the integrated functions of the serotonergic system. The contributed papers include a variety of experimental and computational work, and human clinical studies.