The New Avenues In Bioinformatics
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The New Avenues In Bioinformatics
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Author : Joseph Seckbach
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-11-12
The New Avenues In Bioinformatics written by Joseph Seckbach and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-11-12 with Computers categories.
Bioinformatics has ignited the imagination of scientists, entrepreneurs and the general public. At the meeting place of two fast growth disciplines, biology and computer science Bioinformatics is one of the cornerstones of the new biology. It is clearly pivotal to the translation of high throughput projects such the human genome project into useful knowledge. Yet despite all this attention, there is no consensus on what exactly is Bioinformatics. There are several canonical topics, such as gene structure prediction, protein functional classification or structure prediction. The present book explores new frontiers in bioinformatics, such as Glycomics or the computational modeling of genetic processes. We also discuss confounding factors that we find crucial to the development of the field, such as the ability to protect and restrict intellectual property in the field, or the challenges involved in educating bioinformatics users. Finally, we touch upon some fundamental questions, such as what information is and how it is captured in biological systems. By bringing to the readers such a broad spectrum of reviews, we hope to capture the vibrant spirit of this young science and to truly represent the fast pace with which it is still developing.
New Avenues In Drug Discovery And Bioactive Natural Products
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Author : Raja Chakraborty
language : en
Publisher: Bentham Science Publishers
Release Date : 2023-08-01
New Avenues In Drug Discovery And Bioactive Natural Products written by Raja Chakraborty and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-01 with Medical categories.
New Avenues in Drug Discovery and Bioactive Natural Products is the second volume of the Natural Medicine book series. It is devoted to current research in drug discovery from natural sources. The volume features 13 chapters that cover modern analytical and scientific approaches. The book starts with chapters on advanced analytical and research techniques, such as genomic mining, quality control of herbal drugs, DNA fingerprinting, high-throughput screening, molecular docking and extraction techniques. The contributors provide a summary of challenges for researchers and commercial applications where possible. The book also features chapters dedicated to specific medicinal agents that target a disease (glycosides, SARS-CoV2 spike protein inhibitors, and andrographolides. The collection of important research topics in natural product chemistry aims to help the scholars and researchers in the scientific community that are involved in the extraction and development of new medicines.
The New Avenues In Bioinformatics
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Author : Seckbach
language : en
Publisher:
Release Date : 2006-10-01
The New Avenues In Bioinformatics written by Seckbach and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-10-01 with categories.
The Neurobiology And Genetics Of Gilles De La Tourette Syndrome New Avenues Through Large Scale Collaborative Projects
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Author : Peristera Paschou
language : en
Publisher: Frontiers Media SA
Release Date : 2018-03-13
The Neurobiology And Genetics Of Gilles De La Tourette Syndrome New Avenues Through Large Scale Collaborative Projects written by Peristera Paschou and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-13 with categories.
Gilles de la Tourette Syndrome (TS) is a common, albeit severely under-diagnosed, neuropsychiatric disorder that is caused by a complex genetic basis, interacting with environmental factors. High comorbidity rates with other neurodevelopmental disorders such as attention deficit/hyperactivity disorder and obsessive compulsive disorder raise the intriguing hypothesis of a shared etiological background. Abnormalities of corticostriatal-thalamic-cortical circuits (CSTC) and dysfunction of both dopamine and serotonin neurotransmitter systems are assumed to be associated with TS. Recently, multiple lines of evidence also point towards an important role of additional neurotransmitters such as histamine and glutamate. For a very long time, efforts to elucidate the etiology and pathophysiology of TS have been fragmented and hampered by low statistical power. Finally, after more than two decades of active research aiming to identify the etiology and pathophysiology of TS, we are on the verge of a new era, promising exciting and rapid discoveries in the field. Investigators from around the world, representing multiple disciplines and scientific approaches, are joining their efforts in large-scale initiatives supported both by European Union and US National funding agencies, such as the European-funded EMTICS, TACTICS, and TSGeneSEE consortia, the Marie Curie Initial Training Network TS-EUROTRAIN and the European Society for the Study of TS joining forces with the NIH-funded TSAICG, GGRI, and Tic Genetics consortia. Importantly, all these initiatives are supported by TS patient support and advocacy groups. Multiple resources are being consolidated and coming together to serve the study of TS, including large well-characterized patient cohorts, and specialized epidemiological databases, such as the unique resource of the Netherlands Twin Register. This research topic showcases current large-scale collaborative efforts aiming to elucidate the genetic and neurobiological background of TS, through diverse approaches; from genomewide association studies aiming to identify common variants associated to the disorder to neuroimaging studies and animal models. Furthermore, current approaches on the clinical assessment and management of the disorder are presented. Propelled by the gradual availability of large scale TS cohorts, novel methodologies, and importantly, sheer enthusiasm by multiple researchers working together across different countries, the new era of the neurobiology of TS holds the promise to identify novel targets for improved therapies.
Proceedings Of The 14th International Conference On Computer Engineering And Networks
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Author : Guangqiang Yin
language : en
Publisher: Springer Nature
Release Date : 2025-05-06
Proceedings Of The 14th International Conference On Computer Engineering And Networks written by Guangqiang Yin and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-05-06 with Technology & Engineering categories.
This conference proceedings is a collection of papers accepted for CENet2024 - the 14th International Conference on Computer Engineering and Networks, held in Kashi, China, 18-21 October 2024. The topics covered include Internet of Things and Smart Systems, Artificial Intelligence and Applications, Detection, Analysis and Application of Communication Systems, Cloud Computing and Security, and Medical Engineering and Information Systems. Each section of this book can serve as an excellent reference for industry practitioners, university faculty, research fellows, undergraduate and graduate students who wish to build a knowledge base of the latest advances and state-of-the-art practices in the topics covered. Using this knowledge, they will be able to design, implement and manage systems that are both complex and trustworthy. We would like to thank the authors for their hard work and dedication, and the reviewers for their efforts in ensuring that only the highest quality papers were selected. Without their contributions, the proceedings would not have been possible.
Government Industry Partnerships For The Development Of New Technologies
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2003-02-01
Government Industry Partnerships For The Development Of New Technologies written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-02-01 with Technology & Engineering categories.
This report reviews a variety of partnership programs in the United States, and finds that partnerships constitute a vital positive element of public policy, helping to address major challenges and opportunities at the nexus of science, technology, and economic growth.
Antimicrobial Peptides
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Author : Luis H. Reyes
language : en
Publisher: Elsevier
Release Date : 2024-11-22
Antimicrobial Peptides written by Luis H. Reyes and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-22 with Science categories.
Antimicrobial Peptides: A Roadmap for Accelerating Discovery and Development covers the most important efforts of scientists and engineers worldwide to accelerate the process of discovery, production, and eventual market penetration of more potent antimicrobial peptides. These efforts have been fueled by emerging technologies such as artificial intelligence and data science, molecular and CFD simulations, easy-to-use process simulation packages, microfluidics, 3D-printing, among many others. Such technologies can now be implemented and scaled up quickly and at relatively low cost in low-budget production facilities, critical to moving to sustainable and marketable products worldwide.Discovering novel antimicrobial peptides rationally and cost-effectively has emerged as one of the significant challenges of modern biotechnology. Thus far, this process has been tedious and costly, resulting in molecules with activities far below those needed to address the current challenge of microbial resistance to antibiotics that takes the lives of thousands of people around the world every year. Finally, the book also highlights how multidisciplinary teams have assembled to address the challenges of manufacturing, biological testing, and clinical trials to finally reach complete translation. - Covers computational tools (including emerging artificial intelligence algorithms) and microfluidic systems for discovery and high-throughput screening of AMPs - Discusses the application of bioprocess engineering scale-up approaches for AMPs' production and purification with the aid of process simulation tools and rapid prototyping - Highlights user-centered design and formulation of products with AMPs - Describes the whole pipeline for AMPs production
Concepts In Biotechnology
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Author : Klaus Buchholz
language : en
Publisher: John Wiley & Sons
Release Date : 2014-07-22
Concepts In Biotechnology written by Klaus Buchholz and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-22 with Science categories.
Adopting a unique approach, this novel textbook integrates science and business for an inside view on the biotech industry. Peering behind the scenes, it provides a thorough analysis of the foundations of the present day industry for students and professionals alike: its history, its tools and processes, its markets and products. The authors, themselves close witnesses of the emergence of modern biotechnology from its very beginnings in the 1980s, clearly separate facts from fiction, looking behind the exaggerated claims made by start-up companies trying to attract investors. Essential reading for every student and junior researcher looking for a career in the biotech sector.
Artificial Intelligence And Bioinformatics In Cancer An Interdisciplinary Approach
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Author : Nima Rezaei
language : en
Publisher: Springer Nature
Release Date : 2025-05-30
Artificial Intelligence And Bioinformatics In Cancer An Interdisciplinary Approach written by Nima Rezaei and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-05-30 with Medical categories.
The “Artificial Intelligence and Bioinformatics in Cancer: An Interdisciplinary Approach” is the eighteenth volume of the “Interdisciplinary Cancer Research” series, publishes comprehensive volume on the advances of machine learning and bioinformatics in cancer. The volume starts with a chapter on application of artificial intelligence for early diagnosis of cancer. Then digital health technologies in cancer care and research is discussed. Unveiling cancer complexity: machine learning insights into multi-omics data and the role of integrated bioinformatics in cancer research are also discussed. In silico and biophysical approaches in cancer research and in silico methods and targeted receptors used in cancer studies are explained in the following chapters. The modeling uncertain growth and diffusion in cancer tumors with heterogeneous cell mutations, imaging tumor metabolism and its heterogeneity with special focus on radiomics and artificial intelligence are also discussed. Mathematical modeling of cancer tumor dynamics as well as recent advances in artificial intelligence for cancer treatment are presented, while signature-based drug repositioning for drug discovery employing machine learning tools is also discussed. After a chapter on mathematical analysis of cancer-tumor models, the subsequent chapters discuss on the role of artificial intelligence in colorectal cancer, breast cancer, lung cancer, brain tumor, and cervical cancer. This is the main concept of Cancer Immunology Project (CIP), which is a part of Universal Scientific Education and Research Network (USERN). This interdisciplinary book will be of special value for oncologists who wish to have an update on application of artificial intelligence in diagnosis and treatment of cancers.
Artificial Intelligence And Machine Learning In Drug Design And Development
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Author : Abhirup Khanna
language : en
Publisher: John Wiley & Sons
Release Date : 2024-07-18
Artificial Intelligence And Machine Learning In Drug Design And Development written by Abhirup Khanna and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-07-18 with Computers categories.
The book is a comprehensive guide that explores the use of artificial intelligence and machine learning in drug discovery and development covering a range of topics, including the use of molecular modeling, docking, identifying targets, selecting compounds, and optimizing drugs. The intersection of Artificial Intelligence (AI) and Machine Learning (ML) within the field of drug design and development represents a pivotal moment in the history of healthcare and pharmaceuticals. The remarkable synergy between cutting-edge technology and the life sciences has ushered in a new era of possibilities, offering unprecedented opportunities, formidable challenges, and a tantalizing glimpse into the future of medicine. AI can be applied to all the key areas of the pharmaceutical industry, such as drug discovery and development, drug repurposing, and improving productivity within a short period. Contemporary methods have shown promising results in facilitating the discovery of drugs to target different diseases. Moreover, AI helps in predicting the efficacy and safety of molecules and gives researchers a much broader chemical pallet for the selection of the best molecules for drug testing and delivery. In this context, drug repurposing is another important topic where AI can have a substantial impact. With the vast amount of clinical and pharmaceutical data available to date, AI algorithms find suitable drugs that can be repurposed for alternative use in medicine. This book is a comprehensive exploration of this dynamic and rapidly evolving field. In an era where precision and efficiency are paramount in drug discovery, AI and ML have emerged as transformative tools, reshaping the way we identify, design, and develop pharmaceuticals. This book is a testament to the profound impact these technologies have had and will continue to have on the pharmaceutical industry, healthcare, and ultimately, patient well-being. The editors of this volume have assembled a distinguished group of experts, researchers, and thought leaders from both the AI, ML, and pharmaceutical domains. Their collective knowledge and insights illuminate the multifaceted landscape of AI and ML in drug design and development, offering a roadmap for navigating its complexities and harnessing its potential. In each section, readers will find a rich tapestry of knowledge, case studies, and expert opinions, providing a 360-degree view of AI and ML’s role in drug design and development. Whether you are a researcher, scientist, industry professional, policymaker, or simply curious about the future of medicine, this book offers 19 state-of-the-art chapters providing valuable insights and a compass to navigate the exciting journey ahead. Audience The book is a valuable resource for a wide range of professionals in the pharmaceutical and allied industries including researchers, scientists, engineers, and laboratory workers in the field of drug discovery and development, who want to learn about the latest techniques in machine learning and AI, as well as information technology professionals who are interested in the application of machine learning and artificial intelligence in drug development.