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The Physiological Effects Of High Altitude


The Physiological Effects Of High Altitude
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The Physiological Effects Of High Altitude


The Physiological Effects Of High Altitude
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Author : W. H. Weihe
language : en
Publisher: Elsevier
Release Date : 2015-11-24

The Physiological Effects Of High Altitude written by W. H. Weihe and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-24 with Science categories.


The Physiological Effects of High Altitude covers the concepts and principles in high altitude physiology. This book is divided into four main sections that discuss the adaptive mechanisms in natural acclimatization and the bodily processes of exercise at high altitudes. Some of the topics covered in the book are the development of chronic mountain sickness; comparison of growth and development of the rat at high altitude; body weight during early acclimatization; experiments on wound healing and activity of the adrenocortical system; and experiments on pregnancy and lactation. Other sections deal with the volume and structure of erythrocytes and hemoglobin at high altitude, particularly the responses of deer mice to altitude. This book also examines the hematologic changes during rest and physical activity in man at high altitude. The remaining sections are devoted to the hematologic changes during physical activity, as well as the hypoxic stimulus and mechanism of erythropoiesis. The book can provide useful information to doctors, students, and researchers.



High Altitude Physiology And Medicine


High Altitude Physiology And Medicine
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Author : W. Brendel
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

High Altitude Physiology And Medicine written by W. Brendel and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


High altitude physiology and medicine has again become important. The excep tional achievements of mountaineers who have climbed nearly all peaks over 8,000 m without breathing equipment raise the question of maximal adaptation ca pacity of man to low oxygen pressures. More importantly, the increase in tourism in the Andes and the Himalayas brings over 10,000 people to sites at altitudes above 4,000 and 5,000 m each year. At such heights several kinds of high alti tude diseases are likely to occur, and these complications require detailed medical investigations. Medical authorities need to inform both mountaineers and tourists as to how great a physical burden can be taken in the mountain environment without risk to health. Physicians need to know what kind of prophylaxis is to be employed at high altitudes to prevent the development of diseases and what therapeutic measures should be used once high altitude diseases have occurred. Moreover, the physical condition of the indigenous population living at higher altitudes such as the Andes and the Himalayas, who are exposed continuously to the stress of high altitude, requires our attention. We have become familiar with symptoms characteristic of chronic high-altitude disease: under special conditions this popu lation has a tendency to develop pulmonary hypertension, which is associated with pulmonary edema, pulmonary congestion, and right heart failure.



Harper S Practical Genetic Counselling Eighth Edition


Harper S Practical Genetic Counselling Eighth Edition
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Author : Angus Clarke
language : en
Publisher: CRC Press
Release Date : 2016-06-15

Harper S Practical Genetic Counselling Eighth Edition written by Angus Clarke and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-15 with Medical categories.


Easy to use, and useful when kept close at hand in the room where you work. The book is a pleasure to read: the style elegant and authoritative.' Lancet '...this book is a wonderful reference to enable primary physicians to be informed about their patients.' Annals of Internal Medicine Universally used across the world by genetic counsellors, medical geneticists and clinicians alike, Harper's Practical Genetic Counselling has established itself as the essential guide to counselling those at risk from inherited disorders. Increasingly, common disorders are known to have a genetic component and this book provides invaluable and up to date guidance through the profusion of new information in this area and the associated psychosocial and ethical considerations and concerns. Within its established, tried and trusted framework, the book contains new chapters on: laboratory methods, new genetic sequencing techniques and the applications of genome-wide SNP association studies, genetic susceptibility, cross cultural aspects and the genetic counselling process. It has expand chapters on genetic screening and screening of newborn, treatment techniques and rational approaches to treatment, non-Mendelian inheritance, free fetal DNA in prenatal screening and diagnosis. Key features: - Fully updated to provide the very latest information when in a busy consulting room or clinic - Clear and authoritative advice applicable to everyday clinical practice - Reflects the rapid development of knowledge in this area, including the implications of the human genome project and related technology The eighth edition of this popular, best selling text continues to be an essential source of reference for trainee and practitioner genetic counsellors, medical geneticists and clinicians. Also it provides valuable background for specialist nurses, counsellors, social scientists, ethicists as well as genetics laboratory staff.



Nutritional Needs In Cold And High Altitude Environments


Nutritional Needs In Cold And High Altitude Environments
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 1996-05-15

Nutritional Needs In Cold And High Altitude Environments written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-05-15 with Medical categories.


This book reviews the research pertaining to nutrient requirements for working in cold or in high-altitude environments and states recommendations regarding the application of this information to military operational rations. It addresses whether, aside from increased energy demands, cold or high-altitude environments elicit an increased demand or requirement for specific nutrients, and whether performance in cold or high-altitude environments can be enhanced by the provision of increased amounts of specific nutrients.



Ward Milledge And West S High Altitude Medicine And Physiology


Ward Milledge And West S High Altitude Medicine And Physiology
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Author : Andrew M Luks
language : en
Publisher: CRC Press
Release Date : 2021-02-15

Ward Milledge And West S High Altitude Medicine And Physiology written by Andrew M Luks and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-02-15 with Medical categories.


This pre-eminent work has developed over six editions in response to man's attempts to climb higher and higher unaided, and to spend more time at altitude for both work and recreation. Building on this established reputation, the new and highly experienced authors provide a fully revised and updated text that will help doctors continue to improve the health and safety of all people who visit, live or work in the cold, thin air of high mountains. The sixth edition remains invaluable for any doctor accompanying an expedition or advising patients on a visit to altitude, those specialising in illness and accidents in high places, and for physicians and physiologists who study our dependence on oxygen and the adaptation of the body to altitude.



Physiological And Pathological Responses To Hypoxia And High Altitude


Physiological And Pathological Responses To Hypoxia And High Altitude
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Author : Rodrigo Iturriaga
language : en
Publisher: Frontiers Media SA
Release Date : 2020-06-22

Physiological And Pathological Responses To Hypoxia And High Altitude written by Rodrigo Iturriaga and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-22 with categories.


The appearance of photosynthetic organisms about 3 billion years ago increased the partial pressure of oxygen (PO2) in the atmosphere and enabled the evolution of organisms that use glucose and oxygen to produce ATP by oxidative phosphorylation. Hypoxia is commonly defined as the reduced availability of oxygen in the tissues produced by different causes, which include reduction of atmospheric PO2 as in high altitude, and secondary to pathological conditions such as sleep breathing and pulmonary disorders, anemia, and cardiovascular alterations leading to inadequate transport, delivery, and exchange of oxygen between capillaries and cells. Nowadays, it has been shown that hypoxia plays an important role in the genesis of several human pathologies including cardiovascular, renal, myocardial and cerebral diseases in fetal, young and adult life. Several mechanisms have evolved to maintain oxygen homeostasis. Certainly, all cells respond and adapt to hypoxia, but only a few of them can detect hypoxia and initiate a cascade of signals intended to produce a functional systemic response. In mammals, oxygen detection mechanisms have been extensively studied in erythropoietin-producing cells, chromaffin cells, bulbar and cortical neurons, pulmonary neuroepithelial cells, smooth muscle cells of pulmonary arteries, and chemoreceptor cells. While the precise mechanism underpinning oxygen, sensing is not completely known several molecular entities have been proposed as possible oxygen sensors (i.e. Hem proteins, ion channels, NADPH oxidase, mitochondrial cytochrome oxidase). Remarkably, cellular adaptation to hypoxia is mediated by the master oxygen-sensitive transcription factor, hypoxia-inducible factor-1, which can induce up-regulation of different genes to cope the cellular effects related to a decrease in oxygen levels. Short-term responses to hypoxia included mainly chemoreceptor-mediated reflex ventilatory and hemodynamic adaptations to manage the low oxygen concentration while more prolonged exposures to hypoxia can elicit more sustained physiological responses including switch from aerobic to anaerobic metabolism, vascularization, and enhancement of blood O2 carrying capacity. The focus of this research topic is to provide an up-to-date vision on the current knowledge on oxygen sensing mechanism, physiological responses to acute or chronic hypoxia and cellular/tissue/organ adaptations to hypoxic environment.



Life Heat And Altitude


Life Heat And Altitude
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Author : David Bruce Dill
language : en
Publisher:
Release Date : 1938

Life Heat And Altitude written by David Bruce Dill and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1938 with Science categories.




High Altitude


High Altitude
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Author : Erik R. Swenson
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-26

High Altitude written by Erik R. Swenson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-26 with Medical categories.


​ Over the last decade the science and medicine of high altitude and hypoxia adaptation has seen great advances. High Altitude: Human Adaptation to Hypoxia addresses the challenges in dealing with the changes in human physiology and the particular medical conditions that arise from exposure to high altitude. In-depth and comprehensive chapters cover both the basic science and the clinical consequences of exposure to high altitude. Genetic, cellular, organ and whole body system responses to high altitudes are covered and chapters discuss these effects on a wide range of diseases. Expert authors provide insight into the care of patients with pre-existing medical conditions that fail in some cases to adapt as well as offer insights into how high altitude research can help critically ill patients. High Altitude: Human Adaptation to Hypoxia is an important new volume that offers a window into greater understanding and more successful treatment of hypoxic human diseases.



Harper S Practical Genetic Counselling Eighth Edition


Harper S Practical Genetic Counselling Eighth Edition
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Author : Angus Clarke
language : en
Publisher: CRC Press
Release Date : 2016-06-15

Harper S Practical Genetic Counselling Eighth Edition written by Angus Clarke and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-15 with Medical categories.


Easy to use, and useful when kept close at hand in the room where you work. The book is a pleasure to read: the style elegant and authoritative.' Lancet '...this book is a wonderful reference to enable primary physicians to be informed about their patients.' Annals of Internal Medicine Universally used across the world by genetic counsellors, medical geneticists and clinicians alike, Harper's Practical Genetic Counselling has established itself as the essential guide to counselling those at risk from inherited disorders. Increasingly, common disorders are known to have a genetic component and this book provides invaluable and up to date guidance through the profusion of new information in this area and the associated psychosocial and ethical considerations and concerns. Within its established, tried and trusted framework, the book contains new chapters on: laboratory methods, new genetic sequencing techniques and the applications of genome-wide SNP association studies, genetic susceptibility, cross cultural aspects and the genetic counselling process. It has expand chapters on genetic screening and screening of newborn, treatment techniques and rational approaches to treatment, non-Mendelian inheritance, free fetal DNA in prenatal screening and diagnosis. Key features: - Fully updated to provide the very latest information when in a busy consulting room or clinic - Clear and authoritative advice applicable to everyday clinical practice - Reflects the rapid development of knowledge in this area, including the implications of the human genome project and related technology The eighth edition of this popular, best selling text continues to be an essential source of reference for trainee and practitioner genetic counsellors, medical geneticists and clinicians. Also it provides valuable background for specialist nurses, counsellors, social scientists, ethicists as well as genetics laboratory staff.



High Altitude And Man


High Altitude And Man
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Author : John B. West
language : en
Publisher: Springer
Release Date : 2013-05-27

High Altitude And Man written by John B. West and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-27 with Medical categories.


Leading authorities on high-altitude physiology contribute to this work, which is divided into three sections: Man at Extreme Altitude; Sleep and Restoration at High Altitude; and Physiology of Permanent Residents of High Altitude. Based on a symposium on physiology at high altitude sponsored by the American Physiological Society, the volume includes several chapters on the achievements of the 1981 American Medical Research Expedition to Mt. Everest, where the first physiological measurements at altitudes above 8,000 meters were recorded. With growing interest in the study of human performance in these conditions, this text marks a lasting achievement in high-altitude physiology.