The Platelets
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Platelets
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Author : Alan D. Michelson
language : en
Publisher: Elsevier
Release Date : 2011-08-29
Platelets written by Alan D. Michelson and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-29 with Medical categories.
Platelets, Second Edition is the definitive current source of state-of-the-art knowledge about platelets and covers the entire field of platelet biology, pathophysiology, and clinical medicine. Recently there has been a rapid expansion of knowledge in both basic biology and the clinical approach to platelet-related diseases including thrombosis and hemorrhage. Novel platelet function tests, drugs, blood bank storage methods, and gene therapies have been incorporated into patient care or are in development. This book draws all this information into a single, comprehensive and authoritative resource. First edition won Best Book in Medical Science Award from the Association of American Publishers Contains fourteen new chapters on topics such as platelet genomics and proteomics, inhibition of platelet function by the endothelium, clinical tests of platelet function, real time in vivo imaging of platelets, and inherited thrombocytopenias A comprehensive full color reference comprising over 70 chapters, 1400 pages, and 16,000 references
The Platelets
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Author : Gesina Longenecker
language : en
Publisher: Elsevier
Release Date : 2012-12-02
The Platelets written by Gesina Longenecker and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
The Platelets: Physiology and Pharmacology is a critical review of the basic platelet systems, methodologic critiques, and platelet involvement in major disease states. This book is composed of 20 chapters that specifically deal with the physiology and biochemistry of the platelet system, along with possibilities for, and consequences of, pharmacologic manipulation. The opening chapters examine the basic processes of platelet aggregation and adhesion. These topics are followed by discussions on the types and functions of platelet a-granule proteins; the aspects of adenine nucleotide levels, regulation, and storage; and receptors for catecholamines and consequences of their agonism. Other chapters are devoted to the metabolism of arachidonic acid, its manipulation, consequences, and metabolite receptors. The discussion then shifts to the second-messenger entities, specifically calmodulin, calcium, and cyclic adenosine monophosphate. A chapter presents the comparisons of man and commonly used laboratory animals concerning platelet behavior variability. Another chapter looks into the use and appropriateness of the use of platelets as models of neurons, with a special emphasis on serotonergic neurons. The remaining chapters contain critical reviews of platelet involvement in diabetes, hypertension and peripheral vascular disease, atherogenesis/atherosclerosis, and ischemic heart disease. These chapters also include specific techniques for platelet analysis, including lumiaggregometry, eicosanoid measurements, and serotonin uptake and release. This book is an invaluable source for pharmacologists, biochemists, researchers, and clinicians who are interested in platelet involvement in disease.
Platelets In Thrombotic And Non Thrombotic Disorders
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Author : Paolo Gresele
language : en
Publisher: Springer
Release Date : 2017-03-08
Platelets In Thrombotic And Non Thrombotic Disorders written by Paolo Gresele and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-08 with Medical categories.
This book reviews current science and applications in fields including thrombosis and hemostasis, signal transduction, and non-thrombotic conditions such as inflammation, allergy and tumor metastasis. It is a detailed, up-to-date, highly referenced text for clinical scientists and physicians, including recent developments in this rapidly expanding field. More than a scientific resource, this is also an authoritative reference and guide to the diagnosis.
Disorders Of The Platelets An Issue Of Hematology Oncology Clinics Of North America
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Author : Koneti Rao
language : en
Publisher: Elsevier Health Sciences
Release Date : 2013-06-28
Disorders Of The Platelets An Issue Of Hematology Oncology Clinics Of North America written by Koneti Rao and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-28 with Medical categories.
This issue of Hematology/Oncology Clinics is guest edited by Dr. A. Koneti Rao and focuses on Disorder of the Platelets. Article titles include: Mechanisms of Platelet Activation and Inhibition, Testing Platelet Function,Clinical Implications of Platelet Genomics and Proteomics, Congenital Thrombocytopenias, Immune Thrombocytopenias, Heparin Induced Thrombocytopenia, and Functional defects: Chronic granulomatous disease (CGD) and beyond.
The Platelet And Its Disorders
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Author : B.G. Firkin
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
The Platelet And Its Disorders written by B.G. Firkin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The aim of this book is to introduce the medical student, recent medical graduates involved in postgraduate training and physicians in practice to the role of the platelet in physiology and disease. It is not intended to be an encyclopaedic review of all the literature over the past few decades, but largely represents a personal account, and although resultant prejudices occur, an attempt has been made to emphasize to the reader areas of doubt, and point the way to other sources which may explore these questions more fully in selected references at the end of each chapter. I acknowledge the help of my secretaries, Ms Carolyn Harvey and Mrs Marjorie Brown without whom the book would never have been started, let alone completed. Some illustrations and figures were made by Mr W. Shepherd of Monash University and Ms A. Leaman of the Alfred Hospital. I am indebted to Mrs E. Hagon who read and corrected a number of the chapters, and for the constant help through discussion and debate with my two close collaborators in research, Dr Margaret Howard and Dr Sharron pfueller. Dr Siew Choong, Mrs Maureen Broadway and Ms Ilona Lakatos documented the methods used in our laboratory to study platelets as outlined in the Appendix.
The Platelet
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Author : Kenneth Merle Brinkhous
language : en
Publisher:
Release Date : 1971
The Platelet written by Kenneth Merle Brinkhous and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1971 with Blood coagulation disorders categories.
Platelets And Megakaryocytes
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Author : Jonathan M. Gibbins
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-04
Platelets And Megakaryocytes written by Jonathan M. Gibbins and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-04 with Medical categories.
12 The average human body has in the order of 10 circulating platelets. They are crucial for hemostasis, and yet excessive platelet activation is a major cause of m- bidity and mortality in western societies. It is therefore not surprising that platelets have become one of the most extensively investigated biological cell types. We are, however, far from understanding precisely how platelets become activated under physiological and pathophysiological conditions. In addition, there are large gaps in our knowledge of platelet production from their giant precursor cell, the megakar- cyte. Understanding megakaryocyte biology will be crucial for the development of platelet gene targeting. The aim of Platelets and Megakaryocytes is therefore to bring together established and recently developed techniques to provide a comprehensive guide to the study of both the platelet and the megakaryocyte. It consists of five s- tions split between two volumes. The more functional assays appear in Volume 1, whereas Volume 2 includes signaling techniques, postgenomic methods, and a n- ber of key perspectives chapters. Part I of Volume 1, Platelets and Megakaryocytes: Functional Assays, describes many well established approaches to the study of platelet function, including aggregometry, secretion, arachidonic acid metabolism, procoagulant responses, pla- let adhesion under static or flow conditions, flow cytometry, and production of microparticles. Although one would ideally wish to perform experiments with human platelets, studies within the circulation using intravital microscopy require the use of animal models, which are described in Chapter 16, vol. 1.
Platelets
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Author : Alan D. Michelson
language : en
Publisher: Academic Press
Release Date : 2013-01-09
Platelets written by Alan D. Michelson and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-01-09 with Medical categories.
Platelets - winner of a 2013 Highly Commended BMA Medical Book Award for Internal Medicine - is the definitive current source of state-of-the-art knowledge about platelets and covers the entire field of platelet biology, pathophysiology, and clinical medicine. Recently there has been a rapid expansion of knowledge in both basic biology and the clinical approach to platelet-related diseases including thrombosis and hemorrhage. Novel platelet function tests, drugs, blood bank storage methods, and gene therapies have been incorporated into patient care or are in development. This book draws all this information into a single, comprehensive and authoritative resource. Highly Commended BMA Medical Book Award 2013: Internal Medicine Comprehensive and definitive source of knowledge about platelets for clinicians, pathologists and scientists Integrates the entire field of platelet biology, pathophysiology, and clinical medicine Full color reference comprising 64 chapters, 1400 pages, and 16,000 references Contributions from 126 world leaders in their fields New chapters on topics such as the regulation of platelet life span, platelet microRNAs, GPVI and CLEC-2, monitoring of antiplatelet therapy, novel antiplatelet therapy, and making platelets ex vivo
Disorders Of The Platelets An Issue Of Hematology Oncology Clinics Of North America
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Author : A. Koneti Rao
language : en
Publisher: Clinics: Internal Medicine
Release Date : 2013-06-20
Disorders Of The Platelets An Issue Of Hematology Oncology Clinics Of North America written by A. Koneti Rao and has been published by Clinics: Internal Medicine this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-20 with Medical categories.
This issue of Hematology/Oncology Clinics is guest edited by Dr. A. Koneti Rao and focuses on Disorder of the Platelets. Article titles include: Mechanisms of Platelet Activation and Inhibition, Testing Platelet Function, Clinical Implications of Platelet Genomics and Proteomics, Congenital Thrombocytopenias, Immune Thrombocytopenias, Heparin Induced Thrombocytopenia, and Functional defects: Chronic granulomatous disease (CGD) and beyond
Platelet Transfusion
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Author : T.A. Lister
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Platelet Transfusion written by T.A. Lister and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Platelet transfusion has become an integral part of the management of disseminated malignant disease and its role in preventing or controlling haemorrhage due to thrombocytopenia is now without dispute. This monograph contains articles presented at an Inter national Symposium on Platelet Transfusion held in London in July 1978. It is hoped that they provide an up to-date review of the preparation and laboratory function of platelet concentrates in addition to practical advice towards developing an intelligent approach towards their administration. T.A. Lister j.S. Malpas 9 1 Platelet Collection and Quality Control D. Huestis In this chapter I would like to discuss platelet collection tcchniqlll" and q ualit \7 control; the more clinical aspects will be covered by otl)(, l contributors. In the first place it would be prekrable to l()()k .11 platelets from the point ofvin" of the physician lIsingthern - whatlw needs to know so that his usc of platelets will he intelligent and directed by bac kground knowledge of vvhere platelets are found. hcm they arc halYested and stored. and the clinical realities of platekt t ranslilsion. The platelets we transfuse tomorrow walk the streets today. Intelligent donor recruitment and public information carnpaigm about blood donation, and about new systems of blood donation that arc not yet familiar to the general public, need to be broadcast and developed, but are not really a subject of discussion for this meeting. HISTORICAL REVIEW I shall start with an historical perspective on the evolution of platelet transfusion.