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Therapeutic Drug Monitoring And Clinical Biochemistry


Therapeutic Drug Monitoring And Clinical Biochemistry
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Therapeutic Drug Monitoring And Clinical Biochemistry


Therapeutic Drug Monitoring And Clinical Biochemistry
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Author : Mike Hallworth
language : en
Publisher: AACC Press
Release Date : 1993

Therapeutic Drug Monitoring And Clinical Biochemistry written by Mike Hallworth and has been published by AACC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Biochemistry categories.


This text considers the close inter-relationship of therapeutic drug monitoring and clinical biochemistry. It covers principles of TDM, looking at drug dosage and effect; clinical monitoring and pharmacokinetics; interpretation and response; and near-patient testing. It also includes information on methodology, dosage prediction, drug structure, sampling requirements and target range. The drugs covered include anti-convulsants; aminoglycosides; lithium; anti-arrythmics; xanthines; cyclosporine; methotrexate; and tricyclics. The work also contains case studies.



Clinical Challenges In Therapeutic Drug Monitoring


Clinical Challenges In Therapeutic Drug Monitoring
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Author : William Clarke
language : en
Publisher: Elsevier
Release Date : 2016-07-21

Clinical Challenges In Therapeutic Drug Monitoring written by William Clarke and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-07-21 with Medical categories.


Clinical Challenges in Therapeutic Drug Monitoring: Special Populations, Physiological Conditions and Pharmacogenomics focuses on critical issues in therapeutic drug monitoring including special requirements of therapeutic drug monitoring important to special populations (infants and children, pregnant women, elderly patients, and obese patients). The book also covers issues of free drug monitoring and common interferences in using immunoassays for therapeutic drug monitoring. This book is essential reading for any clinician, fellow, or trainee who wants to gain greater insight into the process of therapeutic drug monitoring for individual dosage adjustment and avoiding drug toxicity for certain drugs within a narrow therapeutic window. The book is written specifically for busy clinicians, fellows, and trainees who order therapeutic drug monitoring and need to get more familiar with testing methodologies, issues of interferences, and interpretation of results in certain patient populations. Offers busy clinicians, pathologists, and trainees a concise resource on the key aspects and critical issues in therapeutic drug monitoring Focuses on patient populations such as infants and children, pregnant women, elderly patients, and obese patients, who have special requirements in therapeutic drug monitoring Explores special topics in therapeutic drug monitoring including free drug monitoring and common immunoassay interference Explains how individual dosage adjustments can prevent drug toxicity for certain drugs within a narrow therapeutic window



Therapeutic Drug Monitoring


Therapeutic Drug Monitoring
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Author : B. Widdrop
language : en
Publisher:
Release Date : 1985

Therapeutic Drug Monitoring written by B. Widdrop and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985 with categories.




Drug Monitoring And Clinical Chemistry


Drug Monitoring And Clinical Chemistry
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Author : Georg Hempel
language : en
Publisher: Elsevier
Release Date : 2004-05-15

Drug Monitoring And Clinical Chemistry written by Georg Hempel and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-05-15 with Science categories.


Drug Monitoring and Clinical Chemistry, the 5th volume in the Handbook of Analytical Separations series, gives an overview about methods to analyse drugs in biological fluids. The most widely used methods to analyse drugs in biological fluids. i.e. chromatographic methods, CE and immunoassays are described in detail. For important drugs, an overview about the methods available and a comparison of the techniques should be given to enable the reader to choose the right method depending on laboratory equipment, staff, the aim of the investigation etc. Other general aspects important for conducting therapeutic drug monitoring or pharmacokinetics studies are also covered, i.e. sample preparation, validation of the analytical methods and pharmacokinetic methods for interpreting the data. Areas where therapeutic drug monitoring is used frequently such as antibiotics, immunosuppressant drugs, antipsychotic and anticancer drugs will be discussed in detail. In addition, the important field of phenotyping and genotyping for therapy optimisation with special focus on real-life applications is also covered. The book contains important information for analyst working on drug analysis in clinical chemistry, hospital pharmacists involved in therapeutic drug monitoring, other pharmacists, chemists or physicians working on pharmacokinetic studies in industry or academia. In contrast to other books in this field, this book provides up-to-date information regarding both methodology and clinical applications. For the applications, only fields are described where therapeutic drug monitoring is used in clinical routine and provides benefit to the patients. Overview of all important field where therapeutic drug monitoring is applied All relevant analytical and computational methods are discussed Written by experts with a lot of practical experience in the field



Recent Advances In Therapeutic Drug Monitoring And Clinical Toxicology


Recent Advances In Therapeutic Drug Monitoring And Clinical Toxicology
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Author : Seth Kwabena Amponsah
language : en
Publisher: Springer Nature
Release Date : 2022-10-25

Recent Advances In Therapeutic Drug Monitoring And Clinical Toxicology written by Seth Kwabena Amponsah and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-25 with Medical categories.


This book gives an overview of therapeutic drug monitoring (TDM) and its clinical application. It also highlights recent advances in toxicological studies, as they relate to therapeutic drug monitoring. This is one of the few books available on the market that covers TDM. Therapeutic drug monitoring (TDM) is a clinical decision-making tool that enables dosage regimen adjustments based on clinical and laboratory measurements. TDM not only involves the measuring of drug concentrations but also interpretation of the results. There is a strong correlation between drug concentrations in body fluids and outcome than between dose and outcome. The chapters include coverage of analytical techniques, pharmacokinetics, therapeutic indices, artificial intelligence and recent advances in toxicological studies. The book fills a gap in published literature and provides reliable information on; Analytical techniques in TDM and clinical toxicology TDM and pharmacokinetic studies TDM of drugs with narrow therapeutic indices Artificial intelligence in TDM and clinical toxicology Future directions and challenges



Therapeutic Drug Monitoring


Therapeutic Drug Monitoring
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Author : B. Widdop
language : en
Publisher:
Release Date : 1985

Therapeutic Drug Monitoring written by B. Widdop and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985 with Medical categories.




Interpretations In Therapeutic Drug Monitoring


Interpretations In Therapeutic Drug Monitoring
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Author : Daniel M. Baer
language : en
Publisher:
Release Date : 1981

Interpretations In Therapeutic Drug Monitoring written by Daniel M. Baer and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981 with Medical categories.




Reference Ranges In Clinical Biochemistry And Notes On Therapeutic Drug Monitoring


Reference Ranges In Clinical Biochemistry And Notes On Therapeutic Drug Monitoring
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Author :
language : en
Publisher:
Release Date : 1993

Reference Ranges In Clinical Biochemistry And Notes On Therapeutic Drug Monitoring written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Children categories.




Therapeutic Drug Monitoring


Therapeutic Drug Monitoring
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Author : Amitava Dasgupta
language : en
Publisher: Academic Press
Release Date : 2012-06-07

Therapeutic Drug Monitoring written by Amitava Dasgupta and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-07 with Medical categories.


Therapeutic Drug Monitoring: Newer Drugs and Biomarkers features timely topics such as the monitoring of classical and newer drugs, pharmacogenomics and the application of biomarkers in therapeutic drug monitoring. This reference also discusses the limitations of current commercially available immunoassays for therapeutic monitoring. It presents new and sophisticated techniques used for proper determination of blood levels and the clinical utility of therapeutic drug monitoring of contemporary drugs. Written by leading international experts and geared toward clinical pathologists, toxicologists, clinical chemists, laboratory professionals and physicians, this book is an essential resource on the current practice of therapeutic drug monitoring in improving patient safety. Includes both the technical and clinical issues associated with therapeutic drug monitoring Discusses the utility of therapeutic drug monitoring of newer drugs such as antiretroviral agents, anticonvulsants, antidepressants etc. Provides up-to-date information on issues in pharmacogenomics and personalized medicine with emphasis on therapy with warfarin, certain anticancer drugs and antidepressants Covers important content on the limitations of commercially available immunoassays (chemical tests) for therapeutic drug monitoring and additional analytical techniques



Advances In Chromatographic Techniques For Therapeutic Drug Monitoring


Advances In Chromatographic Techniques For Therapeutic Drug Monitoring
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Author : Amitava Dasgupta
language : en
Publisher: CRC Press
Release Date : 2009-10-06

Advances In Chromatographic Techniques For Therapeutic Drug Monitoring written by Amitava Dasgupta and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-10-06 with Medical categories.


For drugs with a narrow therapeutic index, therapeutic drug monitoring methods are essential for patient management. Although immunoassays are commercially available for many drugs and most laboratories use these assays for routine therapeutic monitoring, they have many limitations which hinder their efficacy. Providing practical guidelines for imp