Transfer And Expression Of Eukaryotic Genes
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Transfer And Expression Of Eukaryotic Genes
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Author : H.S. Ginsberg
language : en
Publisher: Academic Press
Release Date : 2012-12-02
Transfer And Expression Of Eukaryotic Genes written by H.S. Ginsberg and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
Transfer and Expression of Eukaryotic Genes documents the progress in our understanding of the transfer and expression of eukaryotic genes. This book covers topics organized around three themes: gene expression and its regulation; in vivo gene transfer and development; and viral gene and oncogene systems. This text is divided into three sections encompassing 25 chapters and begins with an overview of the molecular basis of gene expression, with emphasis on transcription complexes that account for transcription control in eukaryotic genes. It then turns to experiments that assess the in vitro stimulatory effect of the SV40 72-bp repeat on specific transcription from heterologous promoter elements using a HeLa whole cell extract. The reader is methodically introduced to the regulation signals and factors of histone gene transcription; transcriptional control of beta-globin and liver-specific genes in mouse cells; and gene transfer in Drosophila and the sea urchin Strongylocentrotus purpuratus. This book also considers the splicing of messenger RNA precursors and the regulation of thymidine kinase enzyme expression, and then concludes with a chapter that describes the activation of the myc oncogene by chromosomal translocation. This book will be of interest to students and researchers in fields ranging from molecular genetics to microbiology, biochemistry, pathology, and immunology.
Eucaryotic Gene Regulation
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Author : Richard Axel
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Eucaryotic Gene Regulation written by Richard Axel and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
Eukaryotic Gene Regulation covers the aspects and mechanisms of gene regulation of selected eukaryotes, such as yeast, Drosophila, and insect. This book is organized into eight parts, encompassing 52 chapters. The majority of the chapters are presented in an experimental manner containing an abstract, methods, results and discussion, and conclusion. This book first gives a short overview of the evolutionary role of interspersion in eukaryotic genes. It then presents considerable chapters on control of gene expression in yeast; gene mutation and isolation; structure and function; and analysis. Part III focuses on genetic and DNA sequence analysis in Drosophila. It includes discussions on allelic complementation and transvection, genetic organization, histone gene, and gene transcription. Part IV examines cell lineage; gene expression and sequences; and protein synthesis of insects, sea urchin, and mammalian cells. This is followed by discussions on structure and expression of specific eukaryotic genes from chicken, rat, rabbit, and human. Topics on the transfer of genetic information within and between cells and the structure and function of chromosome are significantly considered in Parts VI and VII. Genes evaluated in these sections include heavy chain immunoglobulin, light chain, beta-globin, and dihydrofolate reductase. Furthermore, this book describes the in vitro transcription and the factors involved; internal organization and mechanism of assembly of nucleosome; and chromatin structure. The concluding section focuses on aspects of viral genome expression including gene regulation, synthesis, processing, and alternative RNA splicing. Research biologists, geneticists, scientists, teachers, and students will greatly benefit from this book.
Eukaryotic Gene Regulation
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Author : Gerald M. Kolodny
language : en
Publisher: CRC Press
Release Date : 2018-01-18
Eukaryotic Gene Regulation written by Gerald M. Kolodny and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-18 with Medical categories.
The cause of cancer and its many manifestations is at present unknown. Since many of its manifestations, including is control of cell division, appear to represent abnormal patterns of gene expression, studies of the regulation of gene expression nwill provide important insights in the understanding and treatment of cancer. This volume attempts to present some of the recent work on regulation of gene expression in eukaryotic cells.
Gene Regulation In Eukaryotes
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Author : Edgar Wingender
language : en
Publisher: Wiley-Blackwell
Release Date : 1993
Gene Regulation In Eukaryotes written by Edgar Wingender and has been published by Wiley-Blackwell this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Science categories.
A much-needed guide through the overwhelming amount of literature in the field. Comprehensive and detailed, this book combines background information with the most recentinsights. It introduces current concepts, emphasizing the transcriptional control of genetic information. Moreover, it links data on the structure of regulatory proteins with basic cellular processes. Both advanced students and experts will find answers to such intriguing questions as: - How are programs of specific gene repertoires activated and controlled? - Which genes drive and control morphogenesis? - Which genes govern tissue-specific tasks? - How do hormones control gene expression in coordinating the activities of different tissues? An abundant number of clearly presented glossary terms facilitates understanding of the biological background. Speacial feature: over 2200 (!) literature references.
Gene Transfer And Expression
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Author : Michael Kriegler
language : en
Publisher: Springer
Release Date : 1990-06-18
Gene Transfer And Expression written by Michael Kriegler and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990-06-18 with Science categories.
A practical manual of protocols for achieving expression of foreign genes in mammalian cells. It includes some very new techniques such as PCR-based expression. The author gives a theoretical introduction to the protocols and compares the strengths and weaknesses.
Gene Transfer And Expression Protocols
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Author : Edward J. Murray
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-02
Gene Transfer And Expression Protocols written by Edward J. Murray and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-02 with Medical categories.
Biology is the study of living things. The classical approach might be described as holistic and descriptive, whereas the modern molecular - proach aims to be investigative, reductionist, and mechanistic . Genes contain all the information for the structure of all living things ; thus, the understanding of how genes are regulated is an important step toward understanding the nature of living things. The study of gene regulation has been made more tractable by the design of simple expe- mental models in which a single gene can be isolated from the milieu of the organism. The new science of molecular biology has introduced techniques that permit the design of such experimental models. In - sence, the genome of the organism is dissected in such a manner that specific genes may now be introduced into an appropriate cell line . Subsequent analysis of the proteins expressed from the genes under study results in the identification of the regulatory DNA sequences .
Untranslated Gene Regions And Other Non Coding Elements
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Author : Lucy W. Barrett
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-26
Untranslated Gene Regions And Other Non Coding Elements written by Lucy W. Barrett and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-26 with Science categories.
There is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes. Previously dismissed as “junk DNA”, it is the non-coding regions of the genome that are responsible for regulation, facilitating complex temporal and spatial gene expression through the combinatorial effect of numerous mechanisms and interactions working together to fine-tune gene expression. The major regions involved in regulation of a particular gene are the 5’ and 3’ untranslated regions and introns. In addition, pervasive transcription of complex genomes produces a variety of non-coding transcripts that interact with these regions and contribute to regulation. This book discusses recent insights into the regulatory roles of the untranslated gene regions and non-coding RNAs in the control of complex gene expression, as well as the implications of this in terms of organism complexity and evolution.
Gene Regulation
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Author : David S. Latchman
language : en
Publisher: Nelson Thornes
Release Date : 1998
Gene Regulation written by David S. Latchman and has been published by Nelson Thornes this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Science categories.
The previous editions of Gene Regulation have helped students in biological science and medicine gain a full understanding of the issues of gene regulation. In this edition, new material reflects the progress that has been made in the understanding of gene regulation. The most significant change is the addition of an extra chapter describing the basic processes by which DNA is converted in RNA and then into protein. This important new chapter makes this edition complete as a textbook on gene expression and its regulation.
Eukaryotic Genes
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Author : Norman Maclean
language : en
Publisher: Butterworth-Heinemann
Release Date : 1983
Eukaryotic Genes written by Norman Maclean and has been published by Butterworth-Heinemann this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983 with Science categories.
Transcriptional Regulation In Eukaryotes
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Author : Michael F. Carey
language : en
Publisher: CSHL Press
Release Date : 2000
Transcriptional Regulation In Eukaryotes written by Michael F. Carey and has been published by CSHL Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Medical categories.
In the genome era, the analysis of gene expression has become a critical requirement in many laboratories. But there has been no comprehensive source of strategic, conceptual, and technical information to guide this often complex task. Transcriptional Regulation in Eukaryotes answers that need. Written by two experienced investigators, Michael Carey and Stephen Smale at the UCLA School of Medicine, and based in part on the Gene Expression course taught at Cold Spring Harbor Laboratory, this book directly addresses all the concerns of a laboratory studying the regulation of a newly isolated gene and the biochemistry of a new transcription factor. This important and unique book is essential reading for anyone pursuing the analysis of gene expression in model systems or disease states.