Translational Side Of Emerging Invasive And Non Invasive Stimulation Therapies
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Translational Side Of Emerging Invasive And Non Invasive Stimulation Therapies
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Author : Jiande Chen
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-25
Translational Side Of Emerging Invasive And Non Invasive Stimulation Therapies written by Jiande Chen and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-25 with Science categories.
Improving Outcomes In Cerebral Palsy With Early Intervention New Translational Approaches
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Author : Anna Purna Basu
language : en
Publisher: Frontiers E-books
Release Date : 2015-03-30
Improving Outcomes In Cerebral Palsy With Early Intervention New Translational Approaches written by Anna Purna Basu and has been published by Frontiers E-books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-30 with Medicine (General) categories.
The aim of this Research Topic was to collate articles describing prediction of outcomes of pre- and perinatal lesions leading to cerebral palsy, basic research in animal models and human subjects, and ideas for, and trials of, interventions in the first two years of life. CP arises from insults to the sensorimotor cortex, subcortical axon tracts and subplate. The aetiology is complex and often multifactorial. The outcome is not simply a loss of voluntary control due to disruption of descending pathways, but also involves abnormal development of reflex and corticospinal circuitry. CP may be viewed as aberrant plasticity in response to a lesion, indeed, abnormalities in movement are subtle at first but develop subsequently. It is misleading to suppose that developmental mechanisms are self-reparative. The challenge is to understand activitydependent fine tuning of neural circuitry during normal development and to find how to promote desirable plasticity whilst limiting undesirable effects following developmental lesions. However, before proposing interventions, we have to develop our ability to predict the severity of neonatal insults. We solicited a variety of articles, including long and short reviews, original research and opinion pieces, from both basic scientists and clinicians. Likewise we, as editors, have complementary knowledge and experience in this area. Anna Basu is an academic pediatric neurologist and Gavin Clowry is a developmental neuroscientist.
Neuromodulation In Basic Translational And Clinical Research In Psychiatry
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Author : Ryouhei Ishii
language : en
Publisher: Frontiers Media SA
Release Date : 2020-01-20
Neuromodulation In Basic Translational And Clinical Research In Psychiatry written by Ryouhei Ishii and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-20 with categories.
Translational Advances In Alzheimer S Parkinson S And Other Dementia Molecular Mechanisms Biomarkers Diagnosis And Therapies Volume Ii
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Author : Jiehui Jiang
language : en
Publisher: Frontiers Media SA
Release Date : 2022-11-15
Translational Advances In Alzheimer S Parkinson S And Other Dementia Molecular Mechanisms Biomarkers Diagnosis And Therapies Volume Ii written by Jiehui Jiang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-15 with Science categories.
The Safety And Efficacy Of Noninvasive Brain Stimulation In Development And Neurodevelopmental Disorders
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Author : Lindsay M. Oberman
language : en
Publisher: Frontiers Media SA
Release Date : 2015-12-03
The Safety And Efficacy Of Noninvasive Brain Stimulation In Development And Neurodevelopmental Disorders written by Lindsay M. Oberman and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-03 with Neurosciences. Biological psychiatry. Neuropsychiatry categories.
Noninvasive brain stimulation (including Transcranial Magnetic Stimulation (TMS) and Transcranial Current Brain Stimulation (TCS)) can be used both experimentally and therapeutically. In the experimental domain TMS can be applied in single pulses to depolarize a small population of neurons in a targeted brain region. This protocol can be used, for example, to map cortical motor outputs, study central motor conduction time, or evaluate the cortical silent period (a measure of intracortical inhibition) all of which are relevant to neurodevelopment. TMS can also be applied in pairs of pulses (paired pulse stimulation, ppTMS) where two pulses are presented in rapid succession to study intracortical inhibition and facilitation. Trains of repeated TMS (rTMS) pulses can be applied at various stimulation frequencies and patterns to modulate local cortical excitability beyond the duration of the stimulation itself. Depending on the parameters of stimulation the excitability can be either facilitated or suppressed. TCS (including Transcranial Direct Current Stimulation (tDCS), alternating current (tACS), and random noise current stimulation (tRNS) also have the potential to modulate cortical excitability and have also been used to study and modulate cortical activity in healthy and patient populations. The after-effects of rTMS and TCS are thought to be related to changes in efficacy (in either the positive or negative direction) of synaptic connections of the neurons being stimulated, thus these techniques have been used to study and modulate cortical plasticity mechanisms in a number of populations. Recently, researchers have begun to apply these techniques to the study of neurodevelopmental mechanisms as well as the pathophysiology and development of novel treatments for neurodevelopmental disorders. Though there is much promise, caution is warranted given the vulnerability of pediatric and clinical populations and the potential that these techniques have to modify circuit development in a cortex that is in a very dynamic state. This Research Topic hopes to provide an opportunity to share ideas across areas (human and animal researchers, clinicians and basic scientists). We are particularly interested in papers that address issues of choosing a protocol (intensity, frequency, location, coil geometry etc.), populations where noninvasive brain stimulation may have direct impact on diagnostics and treatment, as well as the safety and ethics of applying these techniques in pediatric populations. As many may not be aware of the potential and limitations of noninvasive brain stimulation and its use for research and treatment in this area, this Research Topic promises to have broad appeal. Submissions for all Frontiers article types are encouraged.
Cerebellar Structure And Function In Psychotic Disorders From Mechanisms To Clinics
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Author : Ann K. Shinn
language : en
Publisher: Frontiers Media SA
Release Date : 2024-01-09
Cerebellar Structure And Function In Psychotic Disorders From Mechanisms To Clinics written by Ann K. Shinn and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-09 with Medical categories.
Combinatorial Approaches For Cancer Treatment From Basic To Translational Research
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Author : Daniela Spano
language : en
Publisher: Frontiers Media SA
Release Date : 2022-03-03
Combinatorial Approaches For Cancer Treatment From Basic To Translational Research written by Daniela Spano and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-03 with Science categories.
Neuromodulation
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Author : Elliot Krames
language : en
Publisher: Academic Press
Release Date : 2018-01-05
Neuromodulation written by Elliot Krames and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-05 with Science categories.
Neuromodulation: Comprehensive Textbook of Principles, Technologies, and Therapies, Second Edition, serves as a comprehensive and in-depth reference textbook covering all aspects of the rapidly growing field of neuromodulation. Since the publication of the first edition seven years ago, there has been an explosion of knowledge in neuromodulation, optogenetics, bioelectronics medicine and brain computer interfacing. Users will find unique discussions of the fundamental principles of neuromodulation and therapies, and how they are applied to the brain, spinal cord, peripheral nerves, autonomic nerves and various organs. The book focuses on comprehensive coverage of spinal cord stimulation, non-interventional and interventional brain stimulation, peripheral nerve stimulation, and the emerging fields of neuromodulation, including optogenetics and bioelectronics medicine. - Provides a comprehensive reference that covers all aspects of the growing field of neuromodulation - Written by international, leading authorities in their respective fields of neuromodulation, pain management, functional neurosurgery and biomedical engineering - Includes new chapters on optogenetics, bioelectronics medicine and brain computer interfacing
Human And Animal Models For Translational Research On Neurodegeneration Challenges And Opportunities From South America
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Author : Agustín Ibáñez
language : en
Publisher: Frontiers Media SA
Release Date : 2018-06-21
Human And Animal Models For Translational Research On Neurodegeneration Challenges And Opportunities From South America written by Agustín Ibáñez and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-21 with categories.
Neurodegenerative diseases are the most frequent cause of dementia, representing a burden for public health systems (especially in middle and middle-high income countries). Although most research on this issue is concentrated in first-world centers, growing efforts in South America are affording important breakthroughs. This emerging agenda poses new challenges for the region but also new opportunities for the field. This book aims to integrate the community of experts across the globe and the region, and to establish new challenges and developments for future investigation. We present research focused on neurodegenerative research in South America. We introduce studies assessing the interplay among genetic, neural, and behavioral dimensions of these diseases, as well as articles on vulnerability factors, comparisons of findings from various countries, and works promoting multicenter and collaborative networking. More generally, our book covers a broad scope of human-research approaches (behavioral assessment, neuroimaging, electromagnetic techniques, brain connectivity, peripheral measures), animal methodologies (genetics, epigenetics, proteomics, metabolomics, other molecular biology tools), species (all human and non-human animals, sporadic, and genetic versions), and article types (original research, review, and opinion papers). Through this wide-ranging proposal, we hope to introduce a fresh approach to the challenges and opportunities of research on neurodegeneration in South America.
Advances And Challenges Of Non Invasive Brain Stimulation In Age Related Neurodegenerative Diseases
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Author : Yi Guo
language : en
Publisher: Frontiers Media SA
Release Date : 2022-06-30
Advances And Challenges Of Non Invasive Brain Stimulation In Age Related Neurodegenerative Diseases written by Yi Guo and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-30 with Science categories.