Transmembrane Signalling Intracellular Messengers And Implications For Drug Development
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Transmembrane Signalling Intracellular Messengers And Implications For Drug Development
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Author : S. R. Nahorski
language : en
Publisher:
Release Date : 1990-05-11
Transmembrane Signalling Intracellular Messengers And Implications For Drug Development written by S. R. Nahorski and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990-05-11 with Science categories.
The concept of membrane receptors as components that recognize extracellular ligands and translate their binding into appropriate intracellular responses has been central to pharmacology for more than a century. However, the last few years have seen developments at the molecular level, transforming the discipline of pharmacology. This study examines the latest developments in receptor structure, transmembrane signalling, second messenger generation and second messenger action. It provides access to each of these areas and gives an overview for the future drug manipulation of transmembrane signalling.
Molecular Biology Of The Cell
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Author : Bruce Alberts
language : en
Publisher:
Release Date : 2002
Molecular Biology Of The Cell written by Bruce Alberts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Cytology categories.
Encyclopedia Of Molecular Pharmacology
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Author : Stefan Offermanns
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-08-14
Encyclopedia Of Molecular Pharmacology written by Stefan Offermanns and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-08-14 with Medical categories.
An essential text, this is a fully updated second edition of a classic, now in two volumes. It provides rapid access to information on molecular pharmacology for research scientists, clinicians and advanced students. With the A-Z format of over 2,000 entries, around 350 authors provide a complete reference to the area of molecular pharmacology. The book combines the knowledge of classic pharmacology with the more recent approach of the precise analysis of the molecular mechanisms by which drugs exert their effects. Short keyword entries define common acronyms, terms and phrases. In addition, detailed essays provide in-depth information on drugs, cellular processes, molecular targets, techniques, molecular mechanisms, and general principles.
Microbial Signalling And Communication
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Author : Society for General Microbiology. Symposium
language : en
Publisher: Cambridge University Press
Release Date : 1999-05-06
Microbial Signalling And Communication written by Society for General Microbiology. Symposium and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-05-06 with Medical categories.
Presents information at the forefront of this exciting field and includes contributions on a range of organisms and signalling molecules.
Regulatory Mechanisms In Gastrointestinal Function 1995
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Author : Timothy S. Gaginella
language : en
Publisher: CRC Press
Release Date : 2017-11-22
Regulatory Mechanisms In Gastrointestinal Function 1995 written by Timothy S. Gaginella and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-22 with Medical categories.
Regulatory Mechanisms in Gastrointestinal Function includes a collection of contemporary topics in gastrointestinal research. The control of gastroduodenal electrolyte transport and the influence of drugs on bicarbonate secretion are reviewed in detail. The importance of the interactions between calcium and cyclic-AMP in intestinal secretion is emphasized in a comprehensive chapter that systematically addresses each link in the mechanisms that regulate chloride secretion. Other important topics included in the book are neural reflex modulation of intestinal epithelial transport, the influence of the microcirculation on intestinal secretion, and nitric oxide as a mediator of physiologic and pathophysiologic secretion. The expertise of the authors has resulted in a breadth of important contemporary topics covered in depth.
General Principles
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Author : A.G. Lee
language : en
Publisher: Elsevier
Release Date : 1995-06-28
General Principles written by A.G. Lee and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-06-28 with Science categories.
Progress in understanding the nature of the biological membrane has been very rapid over a broad front, but still pockets of ignorance remain. Application of the techniques of molecular biology has provided the sequences of a very large number of membrane proteins, and has led to the discovery of superfamilies of membrane proteins of related structure. In turn, the identification of these superfamilies has led to new ways of thinking about membrane processes. Many of these processes can now be discussed in molecular terms, and unexpected relationships between apparently unrelated phenomena are bringing a new unity to the study of biological membranes. The quantity of information available about membrane proteins is now too large for any one person to be familiar with anything but a very small part of the primary literature. A series of volumes concentrating on molecular aspects of biological membranes therefore seems timely. The hope is that, when complete, these volumes will provide a convenient introduction to the study of a wide range of membrane functions. This first volume is devoted to general surveys of the structure and synthesis of membrane proteins and lipids, of the interactions between lipids and proteins, and of the functions of biological membranes.
Cooperation Of Liver Cells In Health And Disease
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Author : Z. Kmiec
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Cooperation Of Liver Cells In Health And Disease written by Z. Kmiec and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.
It is only during the last decade that the functions of sinusoidal endothelial cells, Kupffer cells, hepatic stellate cells, pit cells and other intrahepatic lymphocytes have been better understood. The development of methods for isolation and co-culturing various types of liver cells has established that they communicate and cooperate via secretion of various intercellular mediators. This monograph summarizes multiple data that suggest the important role of cellular cross-talk for the functions of both normal and diseased liver. Special features of the book include concise presentation of the majority of detailed data in 19 tables. Original schemes allow for the clear illustration of complicated intercellular relationships. This is the first ever presentation of the newly emerging field of liver biology, which is important for hepatic function in health and disease and opens new avenues for therapeutic interventions.
Selective Neurotoxicity
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Author : Hans Herken
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Selective Neurotoxicity written by Hans Herken and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Following the overwhelmingly successful response to the first printing in hardcover, the hottest topics in Selective Neurotoxicity are now available in this special softcover edition". Researchers are provided with well-grounded information on the cellular and subcellular targets of neurotoxins and their mode of action at the level of ion-channels, receptors and neurotransmitters. The use of bacterial toxins as a tool in neuroscientific research is an important aspect in this context. The chapters that interest clinicians as well deal with protective barriers in the peripheral and central nervous system and metabolic disorders that cause neurotoxins to be built up in the human body. The induction of tumors by neuroptropic carcinogens is included.
Neuromorphic Olfaction
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Author : Krishna C. Persaud
language : en
Publisher: CRC Press
Release Date : 2016-04-19
Neuromorphic Olfaction written by Krishna C. Persaud and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Medical categories.
Many advances have been made in the last decade in the understanding of the computational principles underlying olfactory system functioning. Neuromorphic Olfaction is a collaboration among European researchers who, through NEUROCHEM (Fp7-Grant Agreement Number 216916)-a challenging and innovative European-funded project-introduce novel computing p
Handbook Of Receptors And Channels
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Author : Stephen J. Peroutka
language : en
Publisher: CRC Press
Release Date : 1993-10-20
Handbook Of Receptors And Channels written by Stephen J. Peroutka and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-10-20 with Medical categories.
The cloning, sequencing, and expression of a variety of membrane receptors and channels indicate the existence of at least four "superfamilies" of molecular structures that mediate signal transduction. Presently, more than 400 receptors have been cloned and sequenced. The Handbook of Receptors and Channels is the first handbook series to present the enormous amount of new molecular biological receptor data in a practical and useful format. Each volume in this remarkable series will focus on a specific molecular superfamily of receptors. Complete amino acid sequence information on all cloned receptors, as well as relevant pharmacological information, will be included. Furthermore, the format for each of the volumes will be consistent to allow for easy comparisons of different molecular subtypes for a given transmitter. G Protein-Coupled Receptors is the first volume in this new handbook series. Topics covered in future volumes include: