Using New Metabolic Approaches To Target And Eradicate Cancer Stem Cells
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Using New Metabolic Approaches To Target And Eradicate Cancer Stem Cells
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Author : Michael P. Lisanti
language : en
Publisher: Frontiers Media SA
Release Date : 2022-07-14
Using New Metabolic Approaches To Target And Eradicate Cancer Stem Cells written by Michael P. Lisanti and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-14 with Medical categories.
Topic Editors MPL and FS hold a minority interest in Lunella Biotech, Inc.
Osteosarcoma
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Author : Matthew Gregory Cable
language : en
Publisher: BoD – Books on Demand
Release Date : 2019-12-04
Osteosarcoma written by Matthew Gregory Cable and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-04 with Medical categories.
This book is titled Osteosarcoma - Diagnosis, Mechanisms, and Translational Developments, and focuses on recent advancements and novel ideas in osteosarcoma research. In a manner of speaking, we have taken the multidisciplinary mindset essential for treating osteosarcoma and broadened it to include other areas of cancer research. By learning from gains in other areas of oncology, such as new lncRNAs, the understanding of cancer metabolism and oxidative phosphorylation, and new chemotherapy agents, we can apply them to the niche of osteosarcoma for treatment development. By drawing more attention to these novel and clever discoveries, we hope to continue this enthusiasm for advancements in basic and translational research in the field of osteosarcoma.
Stem Cells From Hype To Real Hope
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Author : Khawaja Husnain Haider
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2018-12-17
Stem Cells From Hype To Real Hope written by Khawaja Husnain Haider and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-12-17 with Medical categories.
This book is a compilation of the bench experience of leading experts from various research labs involved in the cutting edge area of research. The authors describe the use of stem cells both as part of the combinatorial therapeutic intervention approach and as tools (disease model) during drug development, highlighting the shift from a conventional symptomatic treatment strategy to addressing the root cause of the disease process. The book is a continuum of the previously published book entitled "Stem Cells: from Drug to Drug Discovery" which was published in 2017.
Mitochondrial Metabolism
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Author : Jalal Pourahmad
language : en
Publisher: Academic Press
Release Date : 2021-07-28
Mitochondrial Metabolism written by Jalal Pourahmad and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-28 with Science categories.
Mitochondrial Metabolism: An Approach for Disease Management covers mitotherapy from three combined perspectives, Pharmacology, Toxicology and Biochemistry. After an introduction from world-renowned experts, the book's chapters cover the balancing role in reduction/oxidation mitochondria play, mitochondria as targets for therapeutics through its metabolism, mitochondrial contributions to the cell death process, mitochondrial response to environmental toxicants, the mitochondrial role in aging, the impact of calorie restrictive diets, new advances in the identification of altered mitochondria associated signaling pathways in carcinogenesis, and much more. This book provides bioscientists new horizons to realize the importance of mitochondria in present-day research on therapies dealing with mitochondria associated chronic diseases, including diabetes, cancer and neurodegenerative disorders. - Details the significant role of mitochondria in chronic diseases - Presents new insights on the targeting of mitochondria for therapeutic purposes - Includes updated results on mitotherapy and other mitochondria-oriented therapies
Cancer As A Metabolic Disease
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Author : Thomas Seyfried
language : en
Publisher: John Wiley & Sons
Release Date : 2012-06-26
Cancer As A Metabolic Disease written by Thomas Seyfried and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-26 with Science categories.
The book addresses controversies related to the origins of cancer and provides solutions to cancer management and prevention. It expands upon Otto Warburg's well-known theory that all cancer is a disease of energy metabolism. However, Warburg did not link his theory to the "hallmarks of cancer" and thus his theory was discredited. This book aims to provide evidence, through case studies, that cancer is primarily a metabolic disease requring metabolic solutions for its management and prevention. Support for this position is derived from critical assessment of current cancer theories. Brain cancer case studies are presented as a proof of principle for metabolic solutions to disease management, but similarities are drawn to other types of cancer, including breast and colon, due to the same cellular mutations that they demonstrate.
Drug Discovery Stories
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Author : Bin Yu
language : en
Publisher: Elsevier
Release Date : 2024-10-25
Drug Discovery Stories written by Bin Yu and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-10-25 with Business & Economics categories.
Drug Discovery Stories: From Bench to Bedside presents a collection of cases on the development of highly successful pharmaceuticals. It delves into the realm of drug discovery, exploring the structural biology and biological functions of the sought-after targets. The book covers the identification of promising compounds, their transformation from hits to leads through meticulous optimization, and the elucidation of how key compounds interact with the target (in essence, providing invaluable insights for drug design). Additionally, it covers essential information such as the pivotal biological and PK data of lead compounds, any noteworthy clinical results, and a comprehensive overview of other candidate compounds.The field of drug discovery and development has experienced rapid evolution, with numerous new drugs receiving approval each year. While several books have been published on this subject, there is a pressing need for a new book series that accurately reflects the current advancements in drug discovery. This book aims to not only cater to the drug discovery community but also engage other communities involved in chemical biology, synthetic chemistry, and pharmacology. - Analyzes the drug discovery stories of different blockbuster drugs - Includes the newly approved drugs - Covers key aspects related to the drug development of the drugs
Insights In Gastrointestinal Cancers 2021
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Author : Liang Qiao
language : en
Publisher: Frontiers Media SA
Release Date : 2023-03-01
Insights In Gastrointestinal Cancers 2021 written by Liang Qiao and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-01 with Medical categories.
Therapeutic Targeting Of Cancer Stem Like Cells Csc The Current State Of The Art
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Author : Cyril Corbet
language : en
Publisher: Frontiers Media SA
Release Date : 2020-04-03
Therapeutic Targeting Of Cancer Stem Like Cells Csc The Current State Of The Art written by Cyril Corbet and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-03 with categories.
Cancer Ecosystems
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Author : Ubaldo E. Martinez-Outschoorn
language : en
Publisher: Frontiers Media SA
Release Date : 2019-11-27
Cancer Ecosystems written by Ubaldo E. Martinez-Outschoorn and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-27 with categories.
Novel Small Molecule Agents In Overcoming Multidrug Resistance In Cancers
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Author : Qingbin Cui
language : en
Publisher: Frontiers Media SA
Release Date : 2022-05-30
Novel Small Molecule Agents In Overcoming Multidrug Resistance In Cancers written by Qingbin Cui and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-30 with Medical categories.