Virus Host Interactions
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Virus Host Interactions
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Author : Marilena Aquino de Muro
language : en
Publisher: Springer Nature
Release Date : 2022-12-19
Virus Host Interactions written by Marilena Aquino de Muro and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-19 with Medical categories.
This detailed volume spotlights methods to investigate a variety of virus-host interactions in humans, other mammals, fish, or insects. It explores viruses such as white spot syndrome virus (WSSV), honeybee viruses, Nipah virus, EBV, SVCV, HSV-1, HIV-1, A H1N1, and SARS-CoV-2, as well as applications of techniques such as qPCR, serum antibody responses, 4C analysis, cell membrane fusion, biosensors, computational modelling, quantitative proteomics, and other genetic tools to decipher those viral infections and interactions. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Virus-Host Interactions: Methods and Protocols serves as a valuable resource for researchers both in academia and in the biosciences industry who are engaged in the search for a better understanding of threatening virus-hosts interactions, virus detection, their characterization, and ultimately their taming and control.
Comprehensive Virology
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Author : Heinz Fraenkel-Conrat
language : en
Publisher: Springer
Release Date : 1979-12-01
Comprehensive Virology written by Heinz Fraenkel-Conrat and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979-12-01 with Medical categories.
The time seems ripe for a critical compendium of that segment of the biological universe we call viruses. Virology, as a science, having passed only recently through its descriptive phase of naming and num bering, has probably reached that stage at which relatively few new-truly new-viruses will be discovered. Triggered by the intellectual probes and techniques of molecular biology, genetics, bio chemical cytology, and high resolution microscopy and spec troscopy, the field has experienced a genuine information explosion. Few serious attempts have been made to chronicle these events. This comprehensive series, which will comprise some 6000 pages in a total of about 18 volumes, represents a commitment by a large group of active investigators to analyze, digest, and expostulate on the great mass of data relating to viruses, much of which is now amorphous and disjointed, and scattered throughout a wide literature. In this way, we hope to place the entire field in perspective, and to develop an invalua ble reference and sourcebook for researchers and students at all levels. This series is designed as a continuum that can be entered anywhere, but which also provides a logical progression of developing facts and integrated concepts.
Comprehensive Virology
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Author : Heinz Fraenkel-Conrat
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Comprehensive Virology written by Heinz Fraenkel-Conrat and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The time seems ripe for a critical compendium of that segment of the biological universe we call viruses. Virology, as a science, having passed only recently through its descriptive phase of naming and num bering, has probably reached that stage at which relatively few new truly new-viruses will be discovered. Triggered by the intellectual probes and techniques of molecular biology, genetics, biochemical cytology, and high resolution microscopy and spectroscopy, the field has experienced a genuine information explosion. Few serious attempts have been made to chronicle these events. This comprehensive series, which will comprise some 6000 pages in a total of about 18 volumes, represents a commitment by a large group of active investigators to analyze, digest, and expostulate on the great mass of data relating to viruses, much of which is now amorphous and disjointed, and scattered throughout a wide literature. In this way, we hope to place the entire field in perspective, and to develop an invalua ble reference and sourcebook for researchers and students at all levels. This series is designed as a continuum that can be entered anywhere, but which also provides a logical progression of developing facts and integrated concepts.
Comprehensive Virology
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Author : Heinz Fraenkel-Conrat
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Comprehensive Virology written by Heinz Fraenkel-Conrat and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The time seems ripe for a critical compendium of that segment of the biological universe we call viruses. Virology, as a science, having passed only recently through its descriptive phase of naming and num bering, has probably reached that stage at which relatively few new-truly new-viruses will be discovered. Triggered by the intellectual probes and techniques of molecular biology, genetics, bio chemical cytology, and high resolution microscopy and spec troscopy, the field has experienced a genuine information explosion. Few serious attempts have been made to chronicle these events. This comprehensive series, which will comprise some 6000 pages in a total of about 18 volumes, represents a commitment by a large group of active investigators to analyze, digest, and expostulate on the great mass of data relating to viruses, much of which is now amorphous and disjointed, and scattered throughout a wide literature. In this way, we hope to place the entire field in perspective, and to develop an invalua ble reference and sourcebook for researchers and students at all levels. This series is designed as a continuum that can be entered anywhere, but which also provides a logical progression of developing facts and integrated concepts.
Comprehensive Virology
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Author : Heinz Fraenkel-Conrat
language : en
Publisher: Springer
Release Date : 1980-11-01
Comprehensive Virology written by Heinz Fraenkel-Conrat and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980-11-01 with Medical categories.
The time seems ripe for a critical compendium of that segment of the biological universe we call viruses. Virology, as a science, having passed only recently through its descriptive phase of naming and num bering, has probably reached that stage at which relatively few new truly new-viruses will be discovered. Triggered by the intellectual probes and techniques of molecular biology, genetics, biochemical cytology, and high resolution microscopy and spectroscopy, the field has experienced a genuine information explosion. Few serious attempts have been made to chronicle these events. This comprehensive series, which will comprise some 6000 pages in a total of about 18 volumes, represents a commitment by a large group of active investigators to analyze, digest, and expostulate on the great mass of data relating to viruses, much of which is now amorphous and disjointed, and scattered throughout a wide literature. In this way, we hope to place the entire field in perspective, and to develop an invalua ble reference and sourcebook for researchers and students at all levels. This series is designed as a continuum that can be entered anywhere, but which also provides a logical progression of developing facts and integrated concepts.
Archaeal Virus Host Interactions
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Author : Tessa Quax
language : en
Publisher:
Release Date : 2013
Archaeal Virus Host Interactions written by Tessa Quax and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with categories.
The work presented in this thesis provides novel insights in several aspects of the molecular biology of Archaea, Bacteria and their viruses. The archaeal virus Sulfolobus islandicus rod-shaped virus 2 (SIRV2), has a remarkable infection cycle. Infection with SIRV2 results in the formation of large virus associated pyramids (VAPs) on the host cell surface. The pyramids open during the final step of the infection cycle, to allow the release of virions. This virus release mechanism is unique. The VAPs are formed by self-assembly of one virus-encoded protein, PVAP. VAPs exist as discrete particles, and are baseless pyramids with heptagonal perimeter. The assembly process of the VAPs is described, based on cryo-electron tomography experiments and mutational analysis of PVAP. VAPs consists of two layers of which the outer one continuous with the cell membrane. PVAP expression in bacterial and eukaryotic cells resulted in VAP formation on nearly all membranes, demonstrating that PVAP serves as a universal membrane remodeling system, which might be exploited for biotechnological purposes. Whole transcriptome sequencing allowed determination of a global map of virus and host gene expression during the infection cycle. Host genes involved in anti-viral defence are activated (i.e. CRISPR-Cas and toxin anti-toxin systems). The multi-subunit protein complexes crucial for CRISPR anti-viral defence have an uneven stoichiometry and are encoded on operons. It is shown that differential translation is a key determinant of modulated expression of genes clustered in operons and that codon bias generally is the best in silico indicator of unequal protein production.
Viruses Cell Biology And Virus Host Interactions
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Author : Kristin Allen
language : en
Publisher: American Medical Publishers
Release Date : 2023-09-19
Viruses Cell Biology And Virus Host Interactions written by Kristin Allen and has been published by American Medical Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-19 with Science categories.
Viruses are intracellular parasites that are found in all types of life forms, from plants and animals to prokaryotes and archaebacteria. These obligate infectious agents subvert various essential molecular and cellular processes of the host cell. Viruses exploit host cells to replicate and proliferate from cell to cell and from host to host, which leads to an increase in their own population within the host. Infection begins when viruses attach to the surface of the host cell. This means that the viruses bind to one or more cellular receptors, including proteins, carbohydrates and lipids. Viruses not only show the ability to evade immune responses to infect and replicate host cells, but also show the ability to control cellular stress responses such as degradation pathways, autophagy and cell death. Vector-borne viruses usually persist within the vector, but not on other hosts. Viruses often assemble within virus factories, but they can also mature and fold their surface and fusion proteins, depending on the endoplasmic reticulum (ER), Golgi apparatus, and subsequent extracellular pathways. This book is a compilation of chapters that discuss the most vital concepts related to the cell biology of viruses as well as virus-host interactions. It aims to serve as a resource guide for students and experts alike and contribute to the growth of the research on viruses.
Coronaviruses
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Author : Hubert Laude
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Coronaviruses written by Hubert Laude and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Coronaviruses represent a major group of viruses of both molecular biological interest and clinical significance in animals and humans. During the past two decades, coronavirus research has been an expanding field and, since 1980, an international symposium was held every 3 years. We organized the yth symposium for providing an opportunity to assess important progresses made since the last symposium in Cambridge (U. K. ) and to suggest areas for future investigations. The symposium, held in September 1992, in Chantilly, France, was attended by 120 participants representing the majOlity of the laboratories engaged in the field. The present volume collects 75 papers which were presented during the yth symposium, thus providing a comprehensive view of the state of the art ofCoronavirology. The book is divided into 7 chapters. The first chapters gather reports dealing with genome organization, gene expression and structure-function relationships of the viral polypeptides. New sequence data about as yet poorly studied coronaviruses - canine coronavirus CCY and porcine epidemic diarrhoea virus PEDY - are presented. Increasing efforts appear to be devoted to the characterization of products of unknown function, encoded by various open reading frames present in the coronavirus genomes or delived from the processing of the large polymerase polyprotein. Due to the extreme size of their genome, the genetic engineering ofcoronavi\'uses through the production of full length cDNA clones is presently viewed as an unachievahle task.
Plant Virus Host Interaction
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Author : R.K. Gaur
language : en
Publisher: Academic Press
Release Date : 2021-01-12
Plant Virus Host Interaction written by R.K. Gaur and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-01-12 with Science categories.
Plant Virus-Host Interaction: Molecular Approaches and Viral Evolution, Second Edition, provides comprehensive coverage of molecular approaches for virus-host interaction. The book contains cutting-edge research in plant molecular virology, including pathogenic viroids and transport by insect vectors, interference with transmission to control viruses, synergism with pivotal coverage of RNA silencing, and the counter-defensive strategies used by viruses to overcome the silencing response in plants. This new edition introduces new, emerging proteins involved in host-virus interactions and provides in-depth coverage of plant virus genes’ interactions with host, localization and expression. With contributions from leading experts, this is a comprehensive reference for plant virologists, molecular biologists and others interested in characterization of plant viruses and disease management. Introduces new, emerging proteins involved during the host-virus interaction and new virus strains that invade new crops through recombination, resorting and mutation Provides molecular approaches for virus-host interaction Highlights RNA silencing and counter-defensive strategies for disease management Discusses the socioeconomic implications of viral spread and mitigation techniques
Zika Virus And Host Interactions
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Author : Tom Hobman
language : en
Publisher: MDPI
Release Date : 2021-03-24
Zika Virus And Host Interactions written by Tom Hobman and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-24 with Science categories.
Zika virus (ZIKV), one of the flavivirus family members transmitted by mosquitos, was declared a Public Health Emergency of International Concern by the WHO in February 2016 because of clusters of newborn microcephaly cases and other neurological disorders in Brazil. Most ZIKV infections result in a self-limited flu-like febrile disease, however, if contracted during pregnancy, the virus can also infect fetuses and cause a spectrum of birth defects known as congenital Zika syndrome. To date, no vaccines or antiviral drugs are licensed for ZIKV, and the virus has spread and become endemic to many tropical and sub-tropical countries. Included in this book are thirteen reports addressing diverse aspects of ZIKV–host interactions. These studies range from basic science to clinical research. It is expected that findings from these studies will contribute to a better understanding of the host cells interacting with ZIKV, and may serve as the basis for new diagnostics, antiviral therapies, and vaccine design.