Viruses Cell Biology And Virus Host Interactions
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Viruses Cell Biology And Virus Host Interactions
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Author : Kristin Allen
language : en
Publisher: American Medical Publishers
Release Date : 2023-09-19
Viruses Cell Biology And Virus Host Interactions written by Kristin Allen and has been published by American Medical Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-19 with Science categories.
Viruses are intracellular parasites that are found in all types of life forms, from plants and animals to prokaryotes and archaebacteria. These obligate infectious agents subvert various essential molecular and cellular processes of the host cell. Viruses exploit host cells to replicate and proliferate from cell to cell and from host to host, which leads to an increase in their own population within the host. Infection begins when viruses attach to the surface of the host cell. This means that the viruses bind to one or more cellular receptors, including proteins, carbohydrates and lipids. Viruses not only show the ability to evade immune responses to infect and replicate host cells, but also show the ability to control cellular stress responses such as degradation pathways, autophagy and cell death. Vector-borne viruses usually persist within the vector, but not on other hosts. Viruses often assemble within virus factories, but they can also mature and fold their surface and fusion proteins, depending on the endoplasmic reticulum (ER), Golgi apparatus, and subsequent extracellular pathways. This book is a compilation of chapters that discuss the most vital concepts related to the cell biology of viruses as well as virus-host interactions. It aims to serve as a resource guide for students and experts alike and contribute to the growth of the research on viruses.
Molecular And Cellular Biology Of Viruses
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Author : Phoebe Lostroh
language : en
Publisher: CRC Press
Release Date : 2024-03-25
Molecular And Cellular Biology Of Viruses written by Phoebe Lostroh and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-03-25 with Science categories.
This fully revised second edition of Molecular and Cellular Biology of Viruses leads students on an exploration of viruses by supporting engaging and interactive learning. All the major classes of viruses are covered, with separate chapters for their replication and expression strategies, and chapters for mechanisms such as attachment that are independent of the virus genome type. Specific cases drawn from primary literature foster student engagement. End-of-chapter questions focus on analysis and interpretation with answers being given at the back of the book. Examples come from the most-studied and medically important viruses such as SARS-CoV-2, HIV, and influenza. Plant viruses and bacteriophages are also included. There are chapters on the overall effect of viral infection on the host cell. Coverage of the immune system is focused on the interplay between host defenses and viruses, with a separate chapter on medical applications such as antiviral drugs and vaccine development. The final chapter is on virus diversity and evolution, incorporating contemporary insights from metagenomic research. The second edition has updated suggestions for primary literature to discuss along with each chapter. New to this second edition, a supplementary chapter, freely available for download, looks at how virology intersects with public health, and uses the COVID-19 pandemic as a notable example. Key Features Readable but rigorous coverage of the molecular and cellular biology of viruses Molecular mechanisms of all major groups, including plant viruses and bacteriophages, illustrated by example Host-pathogen interactions at the cellular and molecular level emphasized throughout Medical implications and consequences included Quality illustrations available to instructors New to this second edition, interactive quiz questions hosted online
Viruses
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Author : Paula Tennant
language : en
Publisher: Academic Press
Release Date : 2018-03-12
Viruses written by Paula Tennant and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-12 with Science categories.
Viruses: Molecular Biology, Host Interactions, and Applications to Biotechnology provides an up-to-date introduction to human, animal and plant viruses within the context of recent advances in high-throughput sequencing that have demonstrated that viruses are vastly greater and more diverse than previously recognized. It covers discoveries such as the Mimivirus and its virophage which have stimulated new discussions on the definition of viruses, their place in the current view, and their inherent and derived ‘interactomics’ as defined by the molecules and the processes by which virus gene products interact with themselves and their host’s cellular gene products. Further, the book includes perspectives on basic aspects of virology, including the structure of viruses, the organization of their genomes, and basic strategies in replication and expression, emphasizing the diversity and versatility of viruses, how they cause disease and how their hosts react to such disease, and exploring developments in the field of host-microbe interactions in recent years. The book is likely to appeal, and be useful, to a wide audience that includes students, academics and researchers studying the molecular biology and applications of viruses Provides key insights into recent technological advances, including high-throughput sequencing Presents viruses not only as formidable foes, but also as entities that can be beneficial to their hosts and humankind that are helping to shape the tree of life Features exposition on the diversity and versatility of viruses, how they cause disease, and an exploration of virus-host interactions
Harnessing The Power Of Viruses
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Author : Boriana Marintcheva
language : en
Publisher: Academic Press
Release Date : 2017-11-13
Harnessing The Power Of Viruses written by Boriana Marintcheva and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-13 with Science categories.
Harnessing the Power of Viruses explores the application of scientific knowledge about viruses and their lives to solve practical challenges and further advance molecular sciences, medicine and agriculture. The book contains virus-based tools and approaches in the fields of: i) DNA manipulations in vitro and in vivo; ii) Protein expression and characterization; and iii) Virus- Host interactions as a platform for therapy and biocontrol are discussed. It steers away from traditional views of viruses and technology, focusing instead on viral molecules and molecular processes that enable science to better understand life and offer means for addressing complex biological phenomena that positively influence everyday life. The book is written at an intermediate level and is accessible to novices who are willing to acquire a basic level of understanding of key principles in molecular biology, but is also ideal for advanced readers interested in expanding their biological knowledge to include practical applications of molecular tools derived from viruses. Explores virus-based tools and approaches in DNA manipulation, protein expression and characterization and virus-host interactions Provides a dedicated focus on viral molecules and molecular processes that enable science to better understand life and address complex biological phenomena Includes an overview of modern technologies in biology that were developed using viral components/elements and knowledge about viral processes
Virus Host Interactions
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Author : Susanne M. Bailer
language : en
Publisher: Humana
Release Date : 2016-08-23
Virus Host Interactions written by Susanne M. Bailer and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-23 with Medical categories.
Virus-Host Interactions: Methods and Protocols covers various aspects of virological research, such as biochemical approaches, including molecular interactions and regulatory mechanisms on the protein as well as the RNA level with a strong focus on the manifold possibilities to study protein-protein interactions, as well as cell biological and immunological methodologies. Viruses represent a reduced form of life that depends on host cells for propagation. To this end, viruses approach and penetrate cells and usurp cellular machineries for their own benefit. Recent technological improvements have enabled the systematic analysis of the virus-host interplay be it on the genomic, the transcriptomic, or proteomic level. In parallel, bioinformatic tools have emerged in support of the large datasets generated by these high-throughput approaches. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Virus-Host Interactions: Methods and Protocols will prove invaluable to professionals and novices with its well-honed methodologies and protocols.
Proteomics Approaches To Unravel Virus Vertebrate Host Interactions
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Author :
language : en
Publisher: Academic Press
Release Date : 2021-04-30
Proteomics Approaches To Unravel Virus Vertebrate Host Interactions written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-30 with Science categories.
Proteomics Approaches to Unravel Virus - Vertebrate Host Interactions, Volume 109 in the Advances in Virus Research series, highlights state-of-the art mass spectrometry techniques to elucidate the tight interplay of vertebrate viruses and their host cells. The volume includes chapters on Spatio-temporal resolution of host protein complexes during virus entry, Proteomic approaches to investigate gammaherpesvirus biology and associated tumorigenesis, Applications of Mass Spectrometry Imaging in Virus Research, Mapping surfaceome dynamics during viral infection, Characterization of proteolytic events in virus-host interactions, Dynamic protein network modulation upon viral infection, and much more. Discusses the latest methodological breakthroughs in mass spectrometry-based proteomics Reviews how technology has advanced our knowledge on virus-host interactions Provides future perspectives on proteomics research in virology
Plant Virus Interactions
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Author : Tatjana Kleinow
language : en
Publisher: Springer
Release Date : 2016-01-13
Plant Virus Interactions written by Tatjana Kleinow and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-13 with Science categories.
Plant RNA– and DNA-viruses have small genomes and with this limited coding capacity exhibit a strong dependency on host cellular processes and factors to complete their viral life cycle. Various interactions of viral proteins or nucleic acids with host components (proteins, nucleic acids, carbohydrates, lipids and metabolites) evolved, which are essential for a successful systemic spread of viruses within the plant. For example, in plants, transport of endogenous macromolecules like proteins and nucleic acids occurs in a highly selective and regulated manner and viruses exploit these specifically controlled trafficking pathways. Research on plant virus movement is located at the interface of molecular plant virology and plant cell biology. The proposed book project aims to give an overview on the current state of this research and to highlight novel insights into the dynamic interplay between plant viruses and host cells. The book is intended for researchers in plant biology and virology and especially written for those who aim to understand cell biology of virus-plant interactions.
Coronaviruses
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Author : Hubert Laude
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Coronaviruses written by Hubert Laude and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Coronaviruses represent a major group of viruses of both molecular biological interest and clinical significance in animals and humans. During the past two decades, coronavirus research has been an expanding field and, since 1980, an international symposium was held every 3 years. We organized the yth symposium for providing an opportunity to assess important progresses made since the last symposium in Cambridge (U. K. ) and to suggest areas for future investigations. The symposium, held in September 1992, in Chantilly, France, was attended by 120 participants representing the majOlity of the laboratories engaged in the field. The present volume collects 75 papers which were presented during the yth symposium, thus providing a comprehensive view of the state of the art ofCoronavirology. The book is divided into 7 chapters. The first chapters gather reports dealing with genome organization, gene expression and structure-function relationships of the viral polypeptides. New sequence data about as yet poorly studied coronaviruses - canine coronavirus CCY and porcine epidemic diarrhoea virus PEDY - are presented. Increasing efforts appear to be devoted to the characterization of products of unknown function, encoded by various open reading frames present in the coronavirus genomes or delived from the processing of the large polymerase polyprotein. Due to the extreme size of their genome, the genetic engineering ofcoronavi\'uses through the production of full length cDNA clones is presently viewed as an unachievahle task.
Comprehensive Virology
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Author : Heinz Fraenkel-Conrat
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Comprehensive Virology written by Heinz Fraenkel-Conrat and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The time seems ripe for a critical compendium of that segment of the biological universe we call viruses. Virology, as a science, having passed only recently through its descriptive phase of naming and num bering, has probably reached that stage at which relatively few new-truly new-viruses will be discovered. Triggered by the intellectual probes and techniques of molecular biology, genetics, bio chemical cytology, and high resolution microscopy and spec troscopy, the field has experienced a genuine information explosion. Few serious attempts have been made to chronicle these events. This comprehensive series, which will comprise some 6000 pages in a total of about 18 volumes, represents a commitment by a large group of active investigators to analyze, digest, and expostulate on the great mass of data relating to viruses, much of which is now amorphous and disjointed, and scattered throughout a wide literature. In this way, we hope to place the entire field in perspective, and to develop an invalua ble reference and sourcebook for researchers and students at all levels. This series is designed as a continuum that can be entered anywhere, but which also provides a logical progression of developing facts and integrated concepts.
Physical Virology
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Author : Urs F. Greber
language : en
Publisher: Springer
Release Date : 2019-07-17
Physical Virology written by Urs F. Greber and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-17 with Medical categories.
This book explores a new challenge in virology: to understand how physical properties of virus particles (virions) and viruses (infected cells) affect the course of an infection. Insights from the emerging field of physical virology will contribute to understanding of the physical nature of viruses and cells, and will open new ways for anti-viral interference. Nine chapters and an editorial written by physicists, chemists, biologists and computational experts describe how virions serve as trail blazers in uncharted territory of cells. The authors outline how particles change in composition as they interact with host cells. Such virus dynamics are crucial for virus entry into cells and infection. It influences the modern concepts of virus-host interactions, viral lineages and evolution. The volume gives numerous up-to-date examples of modern virology and provides a fascinating read for researchers, clinicians and students in the field of infectious diseases.