Bisphosphonates And Metastatic Bone Disease


Bisphosphonates And Metastatic Bone Disease
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Bisphosphonates And Metastatic Bone Disease


Bisphosphonates And Metastatic Bone Disease
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Author : R. D. Rubens
language : en
Publisher: Parthenon Publishing
Release Date : 1994

Bisphosphonates And Metastatic Bone Disease written by R. D. Rubens and has been published by Parthenon Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Bone metastasis categories.




Bisphosphonates And Tumor Osteolysis


Bisphosphonates And Tumor Osteolysis
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Author : Kurt W. Brunner
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Bisphosphonates And Tumor Osteolysis written by Kurt W. Brunner and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


This volume informs the reader about basic chemical and experimental aspects of the bisphosphonates, their application in neoplastic hypercalcemia, and the basic effects of these drugs in neoplastic osteolysis. Initial reports, which need confirmation by larger randomized studies, also deal with the long-term application and possibly favorable influence of bisphosphonates in metastatic bone disease. It is vital for medical oncologists and interested internists to keep abreast of recent information in this new area of clinical cancer research.



Bone Metastases


Bone Metastases
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Author : Vassilios Vassiliou
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-19

Bone Metastases written by Vassilios Vassiliou and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-19 with Medical categories.


The second edition of this book serves both as an introductory and reference book focusing on the field of metastatic bone disease. Featuring contributions from experts in the field, this volume describes the molecular and cellular mechanisms involved in the formation of bone metastases, presents the newer advances made in the understanding of the clinical picture and symptoms of patients, analyses the role of bone markers in research and clinical practice and deals with all aspects of imaging modalities applied for the detection and evaluation of bone metastases. Moreover, the use of all available treatment methods, such as radiotherapy, surgery and systemic treatments for the management of patients with metastatic bone disease is discussed in detail. Overall this volume presents a thorough overview of all aspects of metastatic bone disease and provides a comprehensive and concise information resource for researchers, oncologists, orthopaedic surgeons and clinicians dealing with patients with metastatic bone disease.



Bone Metastasis


Bone Metastasis
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Author : Gurmit Singh
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-10-28

Bone Metastasis written by Gurmit Singh and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-10-28 with Medical categories.


A state-of-the-art review of the molecular underpinnings of bone-seeking cancers, current treatment approaches for them, and future therapeutic strategies. The authors illuminate the role of various autocrine, paracrine, and immunological factors involved in the progression and establishment of bone metastases, highlighting the physiological processes that lead to bone degradation, pain, angiogenesis, and dysregulation of bone turnover. They also discuss the various strategies that appear to have promise and are currently deployed in treatment or are at the experimental stage.



Metastatic Bone Disease


Metastatic Bone Disease
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Author : R. Lor Randall
language : en
Publisher: Springer Nature
Release Date :

Metastatic Bone Disease written by R. Lor Randall and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.




Textbook Of Bone Metastases


Textbook Of Bone Metastases
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Author : Claude Jasmin
language : en
Publisher: John Wiley & Sons
Release Date : 2005-09-27

Textbook Of Bone Metastases written by Claude Jasmin and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-09-27 with Medical categories.


The epidemiological and clinical importance of bone metastases has long been recognised. For example, the incidence of bone metastases in breast and prostate cancers is 70%, whereas it is only 30 to 40% in metastatic lung cancer. In clinical terms, bone metastases have substantial negative effects on the patient's quality of life. Bone metastases have generally received insufficient attention because of the difficulty in quantifying them, which has left them outside the scope of therapeutic trials This textbook is the result of the remarkable progress made in the understanding of the molecular and cellular mechanisms involved in osteogenesis and osteolysis, and their development for therapeutic purposes. The treatment of malignant hypercalcaemia has also been revolutionised by the use of bisphosphonates. The Textbook of Bone Metastases presents a broad approach to recent progress in all fields related to bone metastases, ranging from epidemiology to the physiopathology of bone metastases and therapeutics. It provides a better understanding of recent advances and, more importantly, will give clinicians all the information needed to help them in the clinical and therapeutic management of patients with bone metastases.



Bisphosphonates In Bone Disease


Bisphosphonates In Bone Disease
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Author : Herbert Fleisch
language : en
Publisher: Elsevier
Release Date : 2000-04-18

Bisphosphonates In Bone Disease written by Herbert Fleisch and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-04-18 with Medical categories.


This book is an essential handbook on bisphosphonates, the most widely used new class of drugs for osteoporosis therapy. It reviews basic physiology in addition to the indications and adverse reactions of these drugs. Bisphosphonates in Bone Disease, 4E, discusses the compounds' chemistry, mechanisms of action, and animal toxicology before presenting a clinical picture of the diseases treated by bisphosphonates. The book provides a table listing the trade names of the commercially available bisphosphonates, registered indications, and the available forms for various countries. The revised Fourth Edition contains approximately 50% new material, including information on all of the latest drugs. * The revised fourth edition contains approximately 50% new material * Includes information on all the latest drugs



Bone Metastases


Bone Metastases
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Author : Robert D. Rubens
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Bone Metastases written by Robert D. Rubens and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


Bone Metastases brings together the many recent developments that are gradually improving the prospects for patients with secondary involvement of the skeleton in a primary cancer elsewhere. The morbidity from bone metastases is extensive, and the palliative and supportive treatment that sufferers require for many months or even years constitutes a major health problem. A multidisciplinary approach is essential since a variety of specialists are involved: radiation and medical oncologists, general and orthopaedic surgeons, general physicians, radiologists and nuclear medicine physicians, symptom control and terminal care specialists. The book's editors, themselves authorities in the fields of oncology and bone disease respectively, have brought together experts from all these disciplines to provide comprehensive coverage of metastatic bone disease. They cover the biology and pathophysiology, hypercalcaemia, imaging, assessment of response to treatment, types of treatment (systemic, radiotherapy, surgery), and symptomatic and supportive care. Particularly new approaches included are magnetic resonance imaging, the assessment of skeletal response and isotope therapy.



Prevention Of Bone Metastases


Prevention Of Bone Metastases
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Author : Markus Joerger
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-01-05

Prevention Of Bone Metastases written by Markus Joerger and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-05 with Medical categories.


Bone metastases continue to be a major cause of morbidity in cancer patients, but improved understanding of the biology of bone metastases has led to the identification of drugs that are of potential value in not only their treatment but also their prevention. This book, written by recognized experts in the field, provides a detailed overview of current knowledge on this subject. One important focus of the book is the efficacy of bisphosphonates in preventing bone metastases in patients with breast, lung, and prostate cancer and disease progression in cases of multiple myeloma. The combined use of bisphosphonates and cytostatics is also discussed, with a report on first clinical data. Further topics addressed include the significance of the bone microenvironment, special issues in the elderly patient, the use of bone turnover markers, and initial findings obtained with denosumab.



Management Of Bone Metastases


Management Of Bone Metastases
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Author : Vincenzo Denaro
language : en
Publisher: Springer
Release Date : 2018-07-25

Management Of Bone Metastases written by Vincenzo Denaro and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-25 with Medical categories.


This highly informative book provides a comprehensive, up-to-date and practical reference for daily clinical practice in the management of patients affected by bone metastases. Written by renowned orthopedic surgeons and leading doctors in the respective fields of expertise, it offers a transversal review of the current medical and surgical treatments to allow a real interdisciplinary approach to the oncologic patient according to the highest current standards. The book illustrates all the fundamental medical treatments for metastatic bone diseases and provides an overview of pathology issues related to this condition. An entire section is devoted to main different methods of patients approach. It also provides guidance on all current surgical procedures and minimally invasive treatment techniques. Using a common language and recognizing the different osteoncologic competences, this work allows surgeons, oncologists, radiologists, pathologists and physiatricians to update their expertise and broaden their understanding of how a real team approach can improve the management of these oncology patients.