Cyclic Nucleotides In The Nervous System
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Cyclic Nucleotides In The Nervous System
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Author : John Daly
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Cyclic Nucleotides In The Nervous System written by John Daly and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The elucidation of the cellular and molecular bases underlying the inte grated function of the central nervous system, both in disease and in health, must ultimately come from the combined efforts of scientists from many disciplines, including biology, chemistry, histology, pathology, physiology, pharmacology, and psychology. Communication between scientists from these various disciplines-vital to the advancement of our understanding of the function of the nervous system-has become more and more difficult in recent years. Both increasing specialization and the incredible increases in publications pertinent to brain research in a wide spectrum of journals, in symposium volumes, in monographs, in abstracts, and in reviews contrib ute to the problems of cross-communication and even of communication within a scientific discipline. Research on the significance of cyclic nucleo tides to the function of nervous systems is particularly illustrative of the communication problem. Since the initial publications by Sutherland, Rall, and Butcher in the late fifties and early sixties on high levels of adenylate cyclase, phosphodiesterases, and cyclic AMP in brain, the ensuing litera ture of this field has expanded exponentially. At the present time, from five to ten publications relevant to cyclic nucleotides and the nervous system appear each week. Indeed, these are minimal numbers based mainly on examination of literature titles and key index words. Many articles concerned with some aspect of central function contain, buried within their text, experiments with or related to cyclic nucleotides.
Cyclic Nucleotides In The Nervous System
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Author : George I. Drummond
language : en
Publisher: New York : Raven Press
Release Date : 1984
Cyclic Nucleotides In The Nervous System written by George I. Drummond and has been published by New York : Raven Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984 with Science categories.
Cyclic Nucleotides In The Nervous System
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Author : George I. Drummond
language : en
Publisher:
Release Date : 1984-01-01
Cyclic Nucleotides In The Nervous System written by George I. Drummond and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984-01-01 with categories.
Cyclic Nucleotide Phosphodiesterases In The Central Nervous System
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Author : Nicholas J. Brandon
language : en
Publisher: John Wiley & Sons
Release Date : 2014-03-07
Cyclic Nucleotide Phosphodiesterases In The Central Nervous System written by Nicholas J. Brandon and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-03-07 with Medical categories.
This book reviews advances in understanding phosphodiesterases within the central nervous system and their therapeutic applications. A range of expert authors from both academia and industry describe these, then focus on the areas of greatest scientific and medical interest to provide more detailed coverage. Therapeutic and drug discovery applications are covered for diseases including Alzheimer's, Parkinson's, schizophrenia, erectile dysfunction, and spinal cord injuries. There is also a chapter on drug discovery tools such as in vitro assays and X-ray structures for medicinal chemistry studies.
Cyclic Nucleotides Phosphorylated Proteins And Neuronal Function
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Author : Paul Greengard
language : en
Publisher:
Release Date : 1978
Cyclic Nucleotides Phosphorylated Proteins And Neuronal Function written by Paul Greengard and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1978 with Medical categories.
The Role Of Cyclic Nucleotides In Central Synaptic Function Renal Transport Of Amino Acids
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Author : Floyd E. Bloom
language : de
Publisher: Springer-Verlag
Release Date : 2019-06-12
The Role Of Cyclic Nucleotides In Central Synaptic Function Renal Transport Of Amino Acids written by Floyd E. Bloom and has been published by Springer-Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-12 with Medical categories.
Minireviews Of The Neurosciences
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Author : Bernard B. Brodie
language : en
Publisher: Elsevier
Release Date : 2013-09-03
Minireviews Of The Neurosciences written by Bernard B. Brodie and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-09-03 with Medical categories.
Minireviews of the Neurosciences from Life Sciences discusses the regulation of tryptophan and tyrosine hydroxylase. This book also addresses the neurochemical correlations of synaptically active amino acids. This book deals first with the role of calcium in the central effects of biogenic amines; neuroendocrinology of human sleep; factors in central serotonergic synapse regulation; noradrenergic mediation of traumatic spinal cord; role of cyclic nucleotides in visual excitation; and function and organization of chromaffin vesicle. Other chapters consider the analysis of nerve growth factor, the sympathetic regulation of thyroid hormone secretion, and the mechanism if trans-synaptic enzyme induction. A study of the functions of the catecholamines and acetylcholine in endocrine regulation is presented. The final chapters examine the effects of brain monoamines in male sexual behavior and the behavior of L-dopa in Parkinson’s disease. The book can provide useful information to neurologists, students, and researchers.
Phosphodiesterases Cns Functions And Diseases
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Author : Han-Ting Zhang
language : en
Publisher: Springer
Release Date : 2017-09-26
Phosphodiesterases Cns Functions And Diseases written by Han-Ting Zhang and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-26 with Medical categories.
PDEs are a family of enzymes that catalyze the hydrolysis of intracellular cyclic nucleotides. They are implicated in a number of disorders and dysfunctions and PDE inhibitors have already proven to be effective therapies for erectile dysfunction, COPD, and psoriatic arthritis. This family of enzymes also plays a role in diseases and disorders of the CNS such as depression, anxiety, schizophrenia, and Alzheimer's Disease. Unfortunately no effective PDE inhibitors have been developed for the treatment of these diseases. The proposed book will be a comprehensive overview of the current state of basic and translational research on PDE inhibitors written by internationally recognized experts. Authors will also discuss potential PDE subtypes and splice variants in the hopes that this will spur more creative approaches to PDE targeting drugs.
Cyclic Nucleotide Signaling
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Author : Xiaodong C. Cheng
language : en
Publisher: CRC Press
Release Date : 2015
Cyclic Nucleotide Signaling written by Xiaodong C. Cheng and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with Cellular signal transduction categories.
Cyclic Nucleotides And Protein Phosphorylation In Cell Regulation
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Author : E.-G. Krause
language : en
Publisher: Elsevier
Release Date : 2014-05-18
Cyclic Nucleotides And Protein Phosphorylation In Cell Regulation written by E.-G. Krause and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-18 with Science categories.
Volume 54, Symposium S7: Cyclic Nucleotides and Protein Phosphorylation in Cell Regulation documents the proceedings of the 12th Federation of European Biochemical Societies (FEBS) Meeting held in Dresden, Germany on July 5-7, 1978. This book discusses the biological significance and biochemical aspects of cyclic nucleotides and protein phosphorylation in cell regulation. The general aspects of cyclic nucleotide metabolism and action; cyclic nucleotides and nervous system; and cyclic nucleotides in muscle tissues are also elaborated. This publication likewise covers the cyclic nucleotides in secretion processes and miscellaneous aspects of cyclic nucleotide-dependent and independent protein phosphorylation. This volume is valuable to biochemists and biologists concerned with the cyclic nucleotides and protein phosphorylation in cell regulation.