Dynamics Of Cancer
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Dynamics Of Cancer
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Author : Dominik Wodarz
language : en
Publisher: World Scientific Publishing Company Incorporated
Release Date : 2014
Dynamics Of Cancer written by Dominik Wodarz and has been published by World Scientific Publishing Company Incorporated this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with Mathematics categories.
The book aims to provide an introduction to mathematical models that describe the dynamics of tumor growth and the evolution of tumor cells. It can be used as a textbook for advanced undergraduate or graduate courses, and also serves as a reference book for researchers. The book has a strong evolutionary component and reflects the viewpoint that cancer can be understood rationally through a combination of mathematical and biological tools. It can be used both by mathematicians and biologists. Mathematically, the book starts with relatively simple ordinary differential equation models, and subsequently explores more complex stochastic and spatial models. Biologically, the book starts with explorations of the basic dynamics of tumor growth, including competitive interactions among cells, and subsequently moves on to the evolutionary dynamics of cancer cells, including scenarios of cancer initiation, progression, and treatment. The book finishes with a discussion of advanced topics, which describe how some of the mathematical concepts can be used to gain insights into a variety of questions, such as epigenetics, telomeres, gene therapy, and social interactions of cancer cells.
Dynamics Of Cancer Mathematical Foundations Of Oncology
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Author : Dominik Wodarz
language : en
Publisher: World Scientific
Release Date : 2014-04-24
Dynamics Of Cancer Mathematical Foundations Of Oncology written by Dominik Wodarz and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-04-24 with Mathematics categories.
The book aims to provide an introduction to mathematical models that describe the dynamics of tumor growth and the evolution of tumor cells. It can be used as a textbook for advanced undergraduate or graduate courses, and also serves as a reference book for researchers. The book has a strong evolutionary component and reflects the viewpoint that cancer can be understood rationally through a combination of mathematical and biological tools. It can be used both by mathematicians and biologists. Mathematically, the book starts with relatively simple ordinary differential equation models, and subsequently explores more complex stochastic and spatial models. Biologically, the book starts with explorations of the basic dynamics of tumor growth, including competitive interactions among cells, and subsequently moves on to the evolutionary dynamics of cancer cells, including scenarios of cancer initiation, progression, and treatment. The book finishes with a discussion of advanced topics, which describe how some of the mathematical concepts can be used to gain insights into a variety of questions, such as epigenetics, telomeres, gene therapy, and social interactions of cancer cells.
Ecology And Evolution Of Cancer
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Author : Beata Ujvari
language : en
Publisher: Academic Press
Release Date : 2017-03-10
Ecology And Evolution Of Cancer written by Beata Ujvari and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-10 with categories.
The Ecology and Evolution of Cancer is a timely work outlining ideas that not only represent a substantial and original contribution to the fields of evolution, ecology and cancer, but also goes beyond by connecting the interface of these disciplines. This work engages the expertise of a multidisciplinary research team to collate and review the latest knowledge and development of this exciting research field. The evolutionary perspective of cancer has gained significant international recognition and interest, which is fully understandable given that somatic cellular selection and evolution are elegant explanations for carcinogenesis. Cancer is now generally accepted to be an evolutionary and ecological process with complex interactions between tumor cells and their environment sharing many similarities with organismal evolution. As a critical contribution to this field of research, The Ecology and Evolution of Cancer is important and relevant for the applications of evolutionary biology to understand the origin of cancers, to control neoplastic progression and to prevent therapeutic failures. Covers all aspects of the evolution of cancer, appealing to researchers seeking to understand its origins and effects of treatments on its progression, as well as lecturers in evolutionary medicine Functions as both an introduction to cancer and evolution and a review of the current research on this burgeoning, exciting field, presented by an international group of leading editors and contributors Improves understanding of the origin and the evolution of cancer, aiding efforts to determine how this disease interferes with biotic interactions that govern ecosystems Highlights research that intends to apply evolutionary principles to help predict emergence and metastatic progression with the aim of improving therapies
Computational Biology Of Cancer
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Author : Dominik Wodarz
language : en
Publisher: World Scientific
Release Date : 2005
Computational Biology Of Cancer written by Dominik Wodarz and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Science categories.
- Provides an introduction to computational methods in cancer biology - Follows a multi-disciplinary approach
Introduction To Mathematical Oncology
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Author : Yang Kuang
language : en
Publisher: CRC Press
Release Date : 2016-04-05
Introduction To Mathematical Oncology written by Yang Kuang and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-05 with Mathematics categories.
Introduction to Mathematical Oncology presents biologically well-motivated and mathematically tractable models that facilitate both a deep understanding of cancer biology and better cancer treatment designs. It covers the medical and biological background of the diseases, modeling issues, and existing methods and their limitations. The authors introduce mathematical and programming tools, along with analytical and numerical studies of the models. They also develop new mathematical tools and look to future improvements on dynamical models. After introducing the general theory of medicine and exploring how mathematics can be essential in its understanding, the text describes well-known, practical, and insightful mathematical models of avascular tumor growth and mathematically tractable treatment models based on ordinary differential equations. It continues the topic of avascular tumor growth in the context of partial differential equation models by incorporating the spatial structure and physiological structure, such as cell size. The book then focuses on the recent active multi-scale modeling efforts on prostate cancer growth and treatment dynamics. It also examines more mechanistically formulated models, including cell quota-based population growth models, with applications to real tumors and validation using clinical data. The remainder of the text presents abundant additional historical, biological, and medical background materials for advanced and specific treatment modeling efforts. Extensively classroom-tested in undergraduate and graduate courses, this self-contained book allows instructors to emphasize specific topics relevant to clinical cancer biology and treatment. It can be used in a variety of ways, including a single-semester undergraduate course, a more ambitious graduate course, or a full-year sequence on mathematical oncology.
Evolutionary Dynamics
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Author : Martin A. Nowak
language : en
Publisher: Harvard University Press
Release Date : 2006-09-29
Evolutionary Dynamics written by Martin A. Nowak and has been published by Harvard University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-09-29 with Science categories.
Evolution is the one theory that transcends all of biology. Nowak draws on the languages of biology and mathematics to outline the mathematical principles according to which life evolves. His book makes a case for understanding every living system—and everything that arises as a consequence of living systems—in terms of evolutionary dynamics.
Biomechanics In Oncology
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Author : Cheng Dong
language : en
Publisher: Springer
Release Date : 2018-10-27
Biomechanics In Oncology written by Cheng Dong and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-27 with Medical categories.
This book covers multi-scale biomechanics for oncology, ranging from cells and tissues to whole organ. Topics covered include, but not limited to, biomaterials in mechano-oncology, non-invasive imaging techniques, mechanical models of cell migration, cancer cell mechanics, and platelet-based drug delivery for cancer applications. This is an ideal book for graduate students, biomedical engineers, and researchers in the field of mechanobiology and oncology. This book also: Describes how mechanical properties of cancer cells, the extracellular matrix, tumor microenvironment and immuno-editing, and fluid flow dynamics contribute to tumor progression and the metastatic process Provides the latest research on non-invasive imaging, including traction force microscopy and brillouin confocal microscopy Includes insight into NCIs’ role in supporting biomechanics in oncology research Details how biomaterials in mechano-oncology can be used as a means to tune materials to study cancer
Multiscale Cancer Modeling
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Author : Thomas S. Deisboeck
language : en
Publisher: CRC Press
Release Date : 2010-12-08
Multiscale Cancer Modeling written by Thomas S. Deisboeck and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-08 with Mathematics categories.
Cancer is a complex disease process that spans multiple scales in space and time. Driven by cutting-edge mathematical and computational techniques, in silico biology provides powerful tools to investigate the mechanistic relationships of genes, cells, and tissues. It enables the creation of experimentally testable hypotheses, the integration of dat
Visualizing Mortality Dynamics In The Lexis Diagram
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Author : Roland Rau
language : en
Publisher: Springer
Release Date : 2017-11-14
Visualizing Mortality Dynamics In The Lexis Diagram written by Roland Rau and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-14 with Social Science categories.
This book visualizes mortality dynamics in the Lexis diagram. While the standard approach of plotting death rates is also covered, the focus in this book is on the depiction of rates of mortality improvement over age and time. This rather novel approach offers a more intuitive understanding of the underlying dynamics, enabling readers to better understand whether period- or cohort-effects were instrumental for the development of mortality in a particular country. Besides maps for single countries, the book includes maps on the dynamics of selected causes of death in the United States, such as cardiovascular diseases or lung cancer. The book also features maps for age-specific contributions to the change in life expectancy, for cancer survival and for seasonality in mortality for selected causes of death in the United States. The book is accompanied by instructions on how to use the freely available R Software to produce these types of surface maps. Readers are encouraged to use the presented tools to visualize other demographic data or any event that can be measured by age and calendar time, allowing them to adapt the methods to their respective research interests. The intended audience is anyone who is interested in visualizing data by age and calendar time; no specialist knowledge is required. This book is open access under a CC BY license.
Characterizing The Multi Faceted Dynamics Of Tumor Cell Plasticity
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Author : Satyendra Chandra Tripathi
language : en
Publisher: Frontiers Media SA
Release Date : 2021-03-01
Characterizing The Multi Faceted Dynamics Of Tumor Cell Plasticity written by Satyendra Chandra Tripathi and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-01 with Science categories.