Experimental Models And Model Organisms In Cardiac Electrophysiology Opportunities And Challenges
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Experimental Models And Model Organisms In Cardiac Electrophysiology Opportunities And Challenges
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Author : Ruben Coronel
language : en
Publisher: Frontiers Media SA
Release Date : 2023-10-05
Experimental Models And Model Organisms In Cardiac Electrophysiology Opportunities And Challenges written by Ruben Coronel and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-05 with Science categories.
Zipes And Jalife S Cardiac Electrophysiology From Cell To Bedside E Book
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Author : Jose Jalife
language : en
Publisher: Elsevier Health Sciences
Release Date : 2021-12-16
Zipes And Jalife S Cardiac Electrophysiology From Cell To Bedside E Book written by Jose Jalife and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-16 with Medical categories.
Fully updated from cover to cover, Zipes and Jalife's Cardiac Electrophysiology: From Cell to Bedside, 8th Edition, provides the comprehensive, multidisciplinary coverage you need—from new knowledge in basic science to the latest clinical advances in the field. Drs. José Jalife and William Gregory Stevenson lead a team of global experts who provide cutting-edge content and step-by-step instructions for all aspects of cardiac electrophysiology. - Packs each chapter with the latest information necessary for optimal basic research as well as patient care. - Covers new technologies such as CRISPR, protein research, improved cardiac imaging, optical mapping, and wearable devices. - Contains significant updates in the areas of molecular biology and genetics, iPSCs (induced pluripotent stem cells), embryonic stem cells, precision medicine, antiarrhythmic drug therapy, cardiac mapping with advanced techniques, and ablation technologies including stereotactic radioablation. - Includes 47 new chapters covering both basic science and clinical topics. - Discusses extensive recent progress in the understanding, diagnosis, and management of arrhythmias, including new clinical insights on atrial fibrillation and stroke prevention, new advances in the understanding of ventricular arrythmias in genetic disease, and advances in implantable devises and infection management. - Features 1,600 high-quality photographs, anatomic and radiographic images, electrocardiograms, tables, algorithms, and more., with additional figures, tables, and videos online. - Recipient of a 2018 Highly Commended award from the British Medical Association. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Computational Methods In Cardiac Electrophysiology
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Author : Matthijs Cluitmans
language : en
Publisher: Frontiers Media SA
Release Date : 2023-07-06
Computational Methods In Cardiac Electrophysiology written by Matthijs Cluitmans and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-06 with Science categories.
Cardiac Electrophysiology Methods And Models
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Author : Paul A. Iaizzo
language : en
Publisher: Springer Nature
Release Date : 2024-12-24
Cardiac Electrophysiology Methods And Models written by Paul A. Iaizzo and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-12-24 with Medical categories.
Cardiovascular disease is the major cause of mortality and morbidity around the world. While significant progress has been made in treating a major sub-category of cardiac disease and arrhythmias, significant unmet needs remain. Every day, thousands of patients die due to arrhythmias in the U.S. alone, and atrial fibrillation is the most common arrhythmia that affects millions of Americans at any given time. Therefore, there is an urgent public need to continue to develop new and better therapies for arrhythmias. This book reviews key research methods and protocols in cardiac electrophysiology with a focus on advantages and pitfalls. It will discuss new developments as well as traditional treatments and methods. Chapters will focus on practical implementation and collaborative cross-functional research methods. The book will contain contributions from scientists and clinicians from various academic and industrial research institutions. The inclusion of industrial experts expands the scope and potential audience of this book, and provides important perspective beyond basic science. Contributors will include researchers and clinicians from academic institutions such as the University of Minnesota, Harvard, Washington University, Case Western, Indiana University, and Manchester University. Methods and Models in Cardiac Electrophysiology will be a must-have resource for clinical academic scientists, engineers from industry (Biotech, Pharma, and Medical Device), undergraduate and graduate students, physicians, biomedical engineers, and high school and college teachers interested in studying cardiac electrophysiology and cardiac function. The book may also be of interest to students in the fields of physiology, molecular biology, cellular biology, biomedical engineering, mechanical engineering, electrical engineering, and related areas.
Integrative Computational Modeling Of Calcium Handling And Cardiac Arrhythmias
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Author : Henry Sutanto
language : en
Publisher: Henry Sutanto
Release Date : 2021-01-01
Integrative Computational Modeling Of Calcium Handling And Cardiac Arrhythmias written by Henry Sutanto and has been published by Henry Sutanto this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-01-01 with Medical categories.
Cardiomyocyte calcium handling is a major determinant of excitation-contraction coupling. Alterations in one or more calcium-handling proteins may induce arrhythmias through the formation of ectopic activity, direct and indirect ion-channel regulation, and structural remodeling. Due to the complex and tight interactions between calcium and other molecules within a cardiomyocyte, it remains experimentally challenging to study the exact contributions of calcium-handling abnormalities to arrhythmogenesis. Multiscale computational studies performed in close collaboration with laboratory experiments create new opportunities to unravel the mechanisms of arrhythmogenesis. This thesis describes the roles of integrative computational modeling in unraveling the arrhythmogenic consequences of calcium-handling abnormalities.
Molecular Genetics Of Cardiac Electrophysiology
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Author : C. Berul
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Molecular Genetics Of Cardiac Electrophysiology written by C. Berul and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The molecular basis for atrial fibrillation continues to be largely unknown, and therapy remains unchanged, aimed at controlling the heart rate and preventing systemic emboli with anticoagulation. Familial atrial fibrillation is more common than previously suspected. While atrial fibrillation is commonly associated with acquired heart disease, a significant proportion of individuals have early onset without other forms of heart disease, referred to as "lone" atrial fibrillators. It is also well recognized that atrial fibrillation occurs on a reversible or functional basis, without associated structural heart disease, such as with hyperthyroidism or of atrial fibrillation following surgery. It remains to be determined what percentage in these individuals is familial or due to a genetic predisposition. Mapping the locus for familial atrial fibrillation is the first step towards the identification of the gene. Isolation of the gene and subsequent identification of the responsible molecular genetic defect should provide a point of entry into the mechanism responsible for the familial form and the common acquired forms of the disease and eventually provide more effective therapy. We know that the ionic currents responsible for the action potential of the atrium is due to multiple channel proteins as is electrical conduction throughout the atria. Analogous to the ongoing genetic studies in patients with familial long QT syndrome, it is highly likely that defects in each of these channel proteins will be manifested in familial atrial fibrillation.
Electrophysiological Disorders Of The Heart E Book
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Author : Sanjeev Saksena
language : en
Publisher: Elsevier Health Sciences
Release Date : 2011-12-12
Electrophysiological Disorders Of The Heart E Book written by Sanjeev Saksena and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-12-12 with Medical categories.
The new edition of Electrophysiological Disorders of the Heart helps you diagnose and treat a full range of heart rhythm disorders using today’s latest technologies and therapies. It provides practical, hands-on coverage of hot topics such as pediatric EP, imaging, echocardiography-guided EP procedures, regenerative therapies, cardiac pacing, and more. Now available in a new full-color format, the title also includes easy online access at www.expertconsult.com. Discover new ways to treat and manage the full range of heart rhythm disorders with content focused on common clinical features, diagnosis, and management. Review expert management strategies to help you handle complex patient problems. Stay current with the latest molecular and technical advances as well as new treatment options implemented over the last few years. Use the latest technologies and devices to accurately diagnose and manage heart rhythm disorders. Consult new and expanded coverage of regenerative therapies, echo-guided procedures, cardiac pacing, and CRT, as well as a new section on pediatric electrophysiology and imaging. Enjoy improved visual guidance with many new full-color images. Log on to www.expertconsult.com to easily search the complete contents online and access a downloadable image library.
Fundamentals Of Toxicologic Pathology
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Author : Matthew A. Wallig
language : en
Publisher: Academic Press
Release Date : 2017-10-25
Fundamentals Of Toxicologic Pathology written by Matthew A. Wallig and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-25 with Medical categories.
Fundamentals of Toxicologic Pathology, Third Edition, presents an essential overview of systems toxicologic pathology in a clear-and-concise manner. Toxicologic pathology integrates toxicology and its interdisciplinary components, including biochemistry, pharmacodynamics and risk assessment to pathology and its related disciplines, such as physiology, microbiology, immunology and molecular biology. This wholly revised and updated edition presents the newest information on the topic, and is an essential reference for advanced students, early career researchers, toxicologic pathologists, pharmaceutical scientists, medical pathologists and clinicians, and anyone involved with drug and device development. The book includes a new section describing the application of toxicologic pathology, such as diagnostic and forensic toxicologic pathology, environmental toxicologic pathology, experimental and industrial toxicologic pathology, and pathology issues in the design of toxicology studies. There are also new chapters on special senses (the eye and ear) and the biochemical and molecular basis of toxicity, among others. - Presents revised and updated information for each chapter on systems - Contains expanded sections on applied toxicologic pathology - Includes the essential information necessary to understand toxicologic pathology in an accessible language
Formal Methods In Macro Biology
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Author : François Fages
language : en
Publisher: Springer
Release Date : 2014-08-14
Formal Methods In Macro Biology written by François Fages and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-08-14 with Computers categories.
This book constitutes the refereed proceedings of the First International Conference on Formal Methods in Macro-Biology, FMMB 2014, held in Nouméa, New Caledonia, in September 2014. The 7 revised full and 3 short papers presented together with 7 invited presentations were carefully reviewed and selected from 17 submissions. The scientific program consists of papers on a wide variety of topics, including ecological systems, medical applications, logical frameworks, and discrete continuous and hybrid models for the analysis of biological systems at macroscopic levels.
Recent Advances In Cardiotoxicity Testing
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Author : Tamer M. A. Mohamed
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-05
Recent Advances In Cardiotoxicity Testing written by Tamer M. A. Mohamed and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-05 with Science categories.