Extracellular Matrix Remodeling In Atherosclerosis
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Extracellular Matrix Remodeling In Atherosclerosis
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Author :
language : en
Publisher:
Release Date :
Extracellular Matrix Remodeling In Atherosclerosis written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Pathogenesis Of Atherosclerosis
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Author : A. Wayne Orr
language : en
Publisher: Biota Publishing
Release Date : 2014-07-01
Pathogenesis Of Atherosclerosis written by A. Wayne Orr and has been published by Biota Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-01 with Medical categories.
The circulatory system provides the tissues of the body with oxygen and nutrients for survival, allows for the dissemination of inflammatory cells, and clears metabolic waste from building up and damaging tissue. Atherosclerotic disease, the build-up of fat, inflammatory cells, and fibrotic tissue in the vessel wall, hinders this function, resulting in inadequate perfusion of the target tissue. Hypoxia, or lack of oxygen, rapidly results in cellular dysfunction that profoundly affects the functionality of the overall tissue. Atherosclerosis-associated tissue ischemia and hypoxia because of loss of blood flow underlies several significant disease pathologies including ischemic heart disease, stroke, and peripheral artery disease. In this eBook, we examine the process of atherosclerotic plaque formation both at the cellular level and the level of clinical presentation. Through this book, we hope to impart to the reader a better understanding of how vessel structure, environmental risk factors, and genetic predisposition contribute to atherosclerotic disease and how current and future therapies seek to circumvent the cellular processes contributing to plaque formation to reduce atherosclerotic plaque burden and clinical complications. Table of Contents: List of Videos / Introduction to Atherosclerosis / Epidemiology / Endothelial Cell Activation and Arterial Hemodynamics / Cholesterol and Cardiovascular Disease / Inflammation in Atherosclerosis / Smooth Muscle Cells and Plaque Vulnerability / Diagnosing Atherosclerotic Disease / Treatment and Prevention / Summary and Future Perspectives / References / Author Biographies
Extracellular Matrix For Cardiovascular Reconstruction
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Author : Steve Bibevski
language : en
Publisher: Frontiers Media SA
Release Date : 2021-06-01
Extracellular Matrix For Cardiovascular Reconstruction written by Steve Bibevski and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-01 with Medical categories.
Topic editor Robert G. Matheny is employed by company CorMatrix Inc.. All other topic editors declare no competing interests with regards to the Research Topic subject.
Cell Interactions In Atherosclerosis
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Author : Horst Robenek
language : en
Publisher: CRC Press
Release Date : 1992-09-25
Cell Interactions In Atherosclerosis written by Horst Robenek and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-09-25 with Medical categories.
Cell Interactions in Atherosclerosis covers the scientific foundations of the most important disease inflicting the developed world today. It presents a collection of topical aspects on the general theme of cell interactions in atherosclerosis, providing authoritative, up-to-the-minute accounts of how new developments in cell biology have advanced our understanding of these cellular interactions. The book is amply illustrated with electron micrographs and light micrographs incorporating modern cytochemical procedures. Cell Interactions in Atherosclerosis will interest all medical and scientific professionals dealing with atherosclerosis and heart disease.
Matrix Metalloproteinases And Tissue Remodeling In Health And Disease Cardiovascular Remodeling
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Author :
language : en
Publisher: Academic Press
Release Date : 2017-04-14
Matrix Metalloproteinases And Tissue Remodeling In Health And Disease Cardiovascular Remodeling written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-14 with Science categories.
Matrix Metalloproteinases and Tissue Remodeling in Health and Disease: Cardiovascular Remodeling is the latest volume in the Progress in Molecular Biology and Translational Science series. This volume is the first part of a thematic and contains up-to-date information on the biology and function of matrix metalloproteinases, and how their effects on tissue remodeling are altered in diseases of the cardiovascular, pulmonary, and musculoskeletal systems and other tissues and organs, as well as cancer. Contributors include prominent scientists and highly-recognized experts with major accomplishments in the research field of matrix metalloproteinases. Focuses on matrix metalloproteinases and their role in tissue remodeling under physiological and pathological conditions Contains up-to-date information on matrix metalloproteinases that is clearly presented in a concise fashion with helpful illustrations and supporting references Includes comprehensive reviews written by prominent scientists and highly-recognized experts in the field of matrix metalloproteinases and tissue remodeling
Atherosclerosis
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Author : Sergey Fedoroff
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Atherosclerosis written by Sergey Fedoroff and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
This volume contains the papers which were presented at the First Altschul Symposium, Atherosclerosis: Cellular and Molecular Interactions in the Artery Wall. The symposium was held in Saskatoon, at the University of Saskatchewan in May 1990 in memory of Dr. Rudolph Altschul, a pioneer in the field of vascular biology and the prevention of atherosclerosis. Dr. Altschul was Professor and Head of the Department of Anatomy at the University of Saskatchewan from 1955 to 1963. The challenge for biomedical scientists is to unravel the multifactorial etiology of atherosclerosis. For the last hundred and sixty years, anatomical pathologists have carefully studied the morphological changes of the human vascular wall during the initiation and evolution of the fibrofatty atherosclerotic plaque. Based on these elegant morphological observations, theories on atherogenesis were put forth by pathologists in the 1840's. Rudolf Virchow suggested that the movement of substances from the blood into the vessel wall was important for atherogenesis while Carl von Rokitansky felt that the deposition of substances on the lumenal surface of the artery resulted in the formation of atherosclerotic plaque. Since these original theories, it has become apparent that the pathogenesis of atherosclerosis is multifactorial and the disease evolves in stages. It is also likely that not all plaques arise through the same sequence of events and that many steps are involved in the development of each plaque. Today, our understanding of the complicated processes of atherogenesis is still incomplete.
Arterial Remodeling A Critical Factor In Restenosis
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Author : Antoine Lafont
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Arterial Remodeling A Critical Factor In Restenosis written by Antoine Lafont and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Angioplasty has completely transformed the treatment of coronary artery disease and is widely used, with more than 800,000 procedures performed worldwide per year. However, the enthusiasm for angioplasty is shadowed by restenosis, which remains a critical problem after the procedure, resulting in clinical recurrence in over a third of patients. Recently, the mechanisms of restenosis have been completely reappraised with an enriched understanding that the original concept of neointimal hyperplasia may not be accounting for the bulk of the problem. There is a desperate need to heighten understanding of the remodeling process at the molecular, cellular, and arterial level. Vascular remodeling is a well established concept in the field of atherosclerosis and hypertension, but only in recent years has its applicability to the field of restenosis become pivotal. Accordingly, the editors perceived the need to assemble the first book dedicated to the concept of coronary artery remodeling in restenosis, in order to clearly review the experiments leading to the remodeling hypothesis and integrate this with the neointimal hyperplasia (tumor) model for the development of the restenotic lesion. The authors of this book present their experience to facilitate the understanding of the mechanisms for coronary restenosis and remodeling. The various experimental models, clinical issues, and basic mechanisms are reviewed in detail, resulting in a fresh approach to a vexing clinical problem. Arterial Remodeling: A Critical Factor in Restenosis will be useful to the physician and trainee who have an interest in restenosis, and specifically in the major pathophysiologic process which determines the fate of arterial healing in patients following percutaneous coronary revascularization. It is hoped that this book will lay the foundation for more effective therapies that will reduce the chance of constrictive remodeling and improve the long-term efficacy of non-surgical coronary revascularization in the future.
Arteriosclerosis
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Author : Hanjörg Just
language : en
Publisher: Springer
Release Date : 1994
Arteriosclerosis written by Hanjörg Just and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Arteriosclerosis categories.
Chemistry And Biology Of Heparin And Heparan Sulfate
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Author : Hari G. Garg
language : en
Publisher: Elsevier
Release Date : 2011-10-10
Chemistry And Biology Of Heparin And Heparan Sulfate written by Hari G. Garg and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-10-10 with Science categories.
The chemistry, biochemistry and pharmacology of heparin and heparan sulfate have been and continue to be a major scientific undertaking - heparin and its derivative remain important drugs in clinical practice. Chemistry and Biology of Heparin and Heparan Sulfate provides readers with an insight into the chemistry, biology and clinical applications of heparin and heparan sulfate and examines their function in various physiological and pathological conditions. Providing a wealth of useful information, no other tome covers the diversity of topics in the field. Students, doctors, chemists, biochemists, and research scientists will find this book an invaluable source for updating their current knowledge of developments in this area. Comprehensively reviews all aspects of heparin and heparan sulfate research Uniquely describes the chemistry, biology and clinical application of heparins and heparan sulfates in one work Provides an invaluable source of knowledge of current developments for chemists, biochemists, medical doctors, researchers, students and practitioners
Mechanisms Of Vascular Disease
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Author : Robert Fitridge
language : en
Publisher: University of Adelaide Press
Release Date : 2011
Mechanisms Of Vascular Disease written by Robert Fitridge and has been published by University of Adelaide Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Medical categories.
New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.