Fed Batch Fermentation
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Fed Batch Cultures
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Author : Henry C. Lim
language : en
Publisher: Cambridge University Press
Release Date : 2013-04-22
Fed Batch Cultures written by Henry C. Lim and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-22 with Technology & Engineering categories.
Many, if not most, industrially important fermentation and bioreactor operations are carried out in fed-batch mode, producing a wide variety of products. In spite of this, there is no single book that deals with fed-batch operations. This is the first book that presents all the necessary background material regarding the 'what, why and how' of optimal and sub-optimal fed-batch operations. Numerous examples are provided to illustrate the application of optimal fed-batch cultures. This unique book, by world experts with decades of research and industrial experience, is a must for researchers and industrial practitioners of fed-batch processes (modeling, control and optimization) in biotechnology, fermentation, food, pharmaceuticals and waste treatment industries.
Fed Batch Fermentation
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Author : G G Moulton
language : en
Publisher: Woodhead Publishing
Release Date : 2014-09-29
Fed Batch Fermentation written by G G Moulton and has been published by Woodhead Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-29 with Science categories.
Fed-batch Fermentation is primarily a practical guide for recombinant protein production in E. coli using a Fed-batch Fermentation process. Ideal users of this guide are teaching labs and R&D labs that need a quick and reproducible process for recombinant protein production. It may also be used as a template for the production of recombinant protein product for use in clinical trials. The guide highlights a method whereby a medium cell density - final Ods = 30-40 (A600) - Fed-batch Fermentation process can be accomplished within a single day with minimal supervision. This process can also be done on a small (2L) scale that is scalable to 30L or more. All reagents (media, carbon source, plasmid vector and host cell) used are widely available and are relatively inexpensive. This method has been used to produce three different protein products following cGMP guidelines for Phase I clinical studies.
Batch Fermentation
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Author : Ali Cinar
language : en
Publisher: CRC Press
Release Date : 2003-04-01
Batch Fermentation written by Ali Cinar and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-04-01 with Science categories.
Illustrating techniques in model development, signal processing, data reconciliation, process monitoring, quality assurance, intelligent real-time process supervision, and fault detection and diagnosis, Batch Fermentation offers valuable simulation and control strategies for batch fermentation applications in the food, pharmaceutical, and chemical industries. The book provides approaches for determining optimal reference trajectories and operating conditions; estimating final product quality; modifying, adjusting, and enhancing batch process operations; and designing integrated real-time intelligent knowledge-based systems for process monitoring and fault diagnosis.
Fed Batch Fermentation
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Author : G G Moulton
language : en
Publisher: Elsevier
Release Date : 2014-10-16
Fed Batch Fermentation written by G G Moulton and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-16 with Science categories.
Fed-batch Fermentation is primarily a practical guide for recombinant protein production in E. coli using a Fed-batch Fermentation process. Ideal users of this guide are teaching labs and R&D labs that need a quick and reproducible process for recombinant protein production. It may also be used as a template for the production of recombinant protein product for use in clinical trials. The guide highlights a method whereby a medium cell density - final Ods = 30-40 (A600) - Fed-batch Fermentation process can be accomplished within a single day with minimal supervision. This process can also be done on a small (2L) scale that is scalable to 30L or more. All reagents (media, carbon source, plasmid vector and host cell) used are widely available and are relatively inexpensive. This method has been used to produce three different protein products following cGMP guidelines for Phase I clinical studies. This process can be used as a teaching tool for the inexperienced fermentation student or researcher in the fields of bioprocessing and bioreactors. It is an important segue from E. coli shake flask cultures to bioreactor The fed-batch fermentation is designed to be accomplished in a single day with the preparation work being done on the day prior The fed-batch fermentation described in this book is a robust process and can be easily scaled for CMO production of protein product
Cell Culture Engineering
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Author : Gyun Min Lee
language : en
Publisher: John Wiley & Sons
Release Date : 2020-01-13
Cell Culture Engineering written by Gyun Min Lee and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-13 with Science categories.
Offers a comprehensive overview of cell culture engineering, providing insight into cell engineering, systems biology approaches and processing technology In Cell Culture Engineering: Recombinant Protein Production, editors Gyun Min Lee and Helene Faustrup Kildegaard assemble top class authors to present expert coverage of topics such as: cell line development for therapeutic protein production; development of a transient gene expression upstream platform; and CHO synthetic biology. They provide readers with everything they need to know about enhancing product and bioprocess attributes using genome-scale models of CHO metabolism; omics data and mammalian systems biotechnology; perfusion culture; and much more. This all-new, up-to-date reference covers all of the important aspects of cell culture engineering, including cell engineering, system biology approaches, and processing technology. It describes the challenges in cell line development and cell engineering, e.g. via gene editing tools like CRISPR/Cas9 and with the aim to engineer glycosylation patterns. Furthermore, it gives an overview about synthetic biology approaches applied to cell culture engineering and elaborates the use of CHO cells as common cell line for protein production. In addition, the book discusses the most important aspects of production processes, including cell culture media, batch, fed-batch, and perfusion processes as well as process analytical technology, quality by design, and scale down models. -Covers key elements of cell culture engineering applied to the production of recombinant proteins for therapeutic use -Focuses on mammalian and animal cells to help highlight synthetic and systems biology approaches to cell culture engineering, exemplified by the widely used CHO cell line -Part of the renowned "Advanced Biotechnology" book series Cell Culture Engineering: Recombinant Protein Production will appeal to biotechnologists, bioengineers, life scientists, chemical engineers, and PhD students in the life sciences.
Automatic Generation Of Process Models For Fed Batch Fermentations Based On The Detection Of Biological Phenomena
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Author : Sebastian Herold
language : en
Publisher:
Release Date : 2015
Automatic Generation Of Process Models For Fed Batch Fermentations Based On The Detection Of Biological Phenomena written by Sebastian Herold and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with categories.
Comprehensive Biotechnology
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Author :
language : en
Publisher: Newnes
Release Date : 2011-08-26
Comprehensive Biotechnology written by and has been published by Newnes this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-26 with Science categories.
The second edition of Comprehensive Biotechnology, Six Volume Set continues the tradition of the first inclusive work on this dynamic field with up-to-date and essential entries on the principles and practice of biotechnology. The integration of the latest relevant science and industry practice with fundamental biotechnology concepts is presented with entries from internationally recognized world leaders in their given fields. With two volumes covering basic fundamentals, and four volumes of applications, from environmental biotechnology and safety to medical biotechnology and healthcare, this work serves the needs of newcomers as well as established experts combining the latest relevant science and industry practice in a manageable format. It is a multi-authored work, written by experts and vetted by a prestigious advisory board and group of volume editors who are biotechnology innovators and educators with international influence. All six volumes are published at the same time, not as a series; this is not a conventional encyclopedia but a symbiotic integration of brief articles on established topics and longer chapters on new emerging areas. Hyperlinks provide sources of extensive additional related information; material authored and edited by world-renown experts in all aspects of the broad multidisciplinary field of biotechnology Scope and nature of the work are vetted by a prestigious International Advisory Board including three Nobel laureates Each article carries a glossary and a professional summary of the authors indicating their appropriate credentials An extensive index for the entire publication gives a complete list of the many topics treated in the increasingly expanding field
Development Of A Novel Two Stage Butanol Production Process Integrating Continuous And Fed Batch Fermentation
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Author : Mpho Setlhaku
language : en
Publisher:
Release Date : 2014
Development Of A Novel Two Stage Butanol Production Process Integrating Continuous And Fed Batch Fermentation written by Mpho Setlhaku and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with categories.
2nd International Workshop On Practical Applications Of Computational Biology And Bioinformatics Iwpacbb 2008
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Author : Juan Manuel Corchado Rodríguez
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-09-16
2nd International Workshop On Practical Applications Of Computational Biology And Bioinformatics Iwpacbb 2008 written by Juan Manuel Corchado Rodríguez and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-09-16 with Technology & Engineering categories.
The success of Bioinformatics in recent years has been prompted by research in mole- lar biology and medicine in initiatives like the human genome project. The volume and diversification of data has increased so much that it is very hard if not impossible to analyze it by human experts. The analysis of this growing body of data, intensified by the development of a number of high-throughput experimental techniques that are generating the so called 'omics' data, has prompted for new computational methods. New global approaches, such as Systems Biology, have been emerging replacing the reductionist view that dominated biology research in the last decades, requiring the coordinated efforts of biological researchers with those related to data analysis, mathematical modelling and computer science. Computational methods have been helping in tasks related to knowledge discovery, modelling and optimization tasks. This workshop brings the opportunity to discuss applications of Bioinformatics and Computational Biology exploring the interactions between computer scientists, bio- gists and other scientific researchers. The IWPACBB technical program includes 29 papers (23 long papers and 6 short papers) selected from a submission pool of 51 papers, from 9 different countries. We thank the excellent work of the local organization members and also from the members of the Program Committee for their excellent reviewing work. October 2008 Juan M. Corchado Juan F. De Paz Miguel P. Rocha Florentino Fernández Riverola Organization
Fed Batch Cultures
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Author : Henry C. Lim. Hwa Sung Shin
language : en
Publisher:
Release Date : 2013
Fed Batch Cultures written by Henry C. Lim. Hwa Sung Shin and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with categories.