From Imaging To Inflammation Exploring Neurodegenerative Mechanisms Through Advanced Techniques
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From Imaging To Inflammation Exploring Neurodegenerative Mechanisms Through Advanced Techniques
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Author : Ali Keshavarzian
language : en
Publisher: Nobel Sciences
Release Date : 2025-04-07
From Imaging To Inflammation Exploring Neurodegenerative Mechanisms Through Advanced Techniques written by Ali Keshavarzian and has been published by Nobel Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-04-07 with Medical categories.
Chapters Chapter 1: Advances in Neuroimaging Techniques: Applications of fMRI, PET, and EEG in Understanding Brain Dynamics Chapter 2: Neuroinflammation: Mechanisms and Therapeutic Targets in Neurodegenerative Diseases Chapter 3: Multimodal Imaging Approaches in Neuroscience Chapter 4: Biomarkers of Neuroinflammation in Neurodegenerative Diseases
Glial Dysfunction In Epileptogenesis
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Author : Kjell Heuser
language : en
Publisher: Frontiers Media SA
Release Date : 2021-09-14
Glial Dysfunction In Epileptogenesis written by Kjell Heuser and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-14 with Medical categories.
Advanced Microscopy
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Author : Merin Sara Thomas
language : en
Publisher: CRC Press
Release Date : 2022-12-23
Advanced Microscopy written by Merin Sara Thomas and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-23 with Science categories.
This interdisciplinary book, Advanced Microscopy: A Strong Analytical Tool in Materials Science, covers the methodology and applications of different advanced microscopic techniques in various research fields, including chemistry, nanotechnology, polymers, chemical engineering, and biomedical engineering, providing an informative overview that helps to determine the best applications for advanced materials. Materials usually behave very differently at nanoscale in all aspects, and this volume shows how microscopy can help provide a detailed understanding of materials such as semiconductors, metals, polymers, biopolymers, etc. The volume illustrates advanced microscopic techniques that include scanning electron microscopy (SEM), transmission electron microscopy (TEM), atomic force microscopy (AFM), confocal microscopy, and others. The microscopy techniques presented in the volume show applications in many areas of science, including botany and plant science, medicine, nanotechnology, chemistry, food science, waste management, and others. This book presents the diverse advanced microscopic techniques for researchers, giving a better understanding as well as implementation of novel techniques in materials science.
Neuroimaging From Research To Clinical Practice
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Author : Sara Palermo
language : en
Publisher: BoD – Books on Demand
Release Date : 2025-07-16
Neuroimaging From Research To Clinical Practice written by Sara Palermo and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-07-16 with Medical categories.
Neuroimaging has transitioned from the laboratory to the clinic at an unprecedented pace, becoming a standard diagnostic, monitoring, and treatment tool for neurological and psychiatric diseases. In this book, a clear description of this revolution is provided, emphasizing how novel imaging techniques are reshaping contemporary medicine. Organized into three sections, the book opens with the examination of brain development, describing how state-of-the-art diffusion MRI reveals the dynamic architecture of the developing brain. The opening chapter emphasizes the promise of early imaging in identifying neurodevelopmental disorders. The second section is dedicated to clinical applications. Chapters cover the correspondence between neuroimaging features and disease, the use of nuclear medicine methodology in dementia, epilepsy, and movement disorders, and the diagnostic value of PET/CT, illustrated by case-based examples. These chapters offer practical insights into enhanced diagnostic accuracy and therapeutic support through multimodal imaging. The third section of the book acquaints readers with interventional and surgical applications. This section illustrates how imaging today is directly applied in therapy, from treatment under imaging guidance to neuronavigation and neuromodulation interventions. Trends for the future, such as the incorporation of AI, portable imaging, and augmented reality into the operating room, are also discussed. Authored by international experts, this book is intended for clinicians, researchers, and students interested in the clinical applications of neuroimaging. It links current research with everyday medical practice using case-based examples and practical frameworks. Neuroimaging – From Research to Clinical Practice is a reference and a guide to how brain imaging shapes modern treatment approaches.
Understanding Alzheimer S A Guide To Memory Mind And Life
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Author : Dr. Nilesh Panchal
language : en
Publisher: DrMedHealth
Release Date : 2024-11-09
Understanding Alzheimer S A Guide To Memory Mind And Life written by Dr. Nilesh Panchal and has been published by DrMedHealth this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-09 with Medical categories.
"Understanding Alzheimer's: A Guide to Memory, Mind, and Life" explores the complex and fascinating world of Alzheimer’s Disease, delving into the biology behind memory decline, cognitive impairment, and brain changes that characterize this condition. This book unpacks the latest scientific research on the molecular and cellular processes that contribute to Alzheimer’s, including the formation of amyloid plaques and tau tangles, as well as genetic and environmental risk factors. With accessible explanations and insights from top researchers, readers gain a clear understanding of the diagnostic tools, therapeutic approaches, and potential future breakthroughs that could transform Alzheimer’s care. This is an essential guide for anyone looking to grasp the underlying science of Alzheimer’s and to better understand the pathways to hope and discovery in treating this disease.
Mechanisms Of Neuroinflammation And Inflammatory Neurodegeneration In Acute Brain Injury
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Author : Arthur Liesz
language : en
Publisher: Frontiers Media SA
Release Date : 2015-11-13
Mechanisms Of Neuroinflammation And Inflammatory Neurodegeneration In Acute Brain Injury written by Arthur Liesz and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-11-13 with Neurosciences. Biological psychiatry. Neuropsychiatry categories.
Mechanisms of brain-immune interactions became a cutting-edge topic in systemic neurosciences over the past years. Acute lesions of the brain parenchyma, particularly, induce a profound and highly complex neuroinflammatory reaction with similar mechanistic properties between differing disease paradigms like ischemic stroke, intracerebral hemorrhage (ICH) and traumatic brain injury (TBI). Resident microglial cells sense tissue damage and initiate inflammation, activation of the endothelial brain-immune interface promotes recruitment of systemic immune cells to the brain and systemic humoral immune mediators (e.g. complements and cytokines) enter the brain through the damaged blood-brain barrier. These cellular and humoral constituents of the neuroinflammatory reaction to brain injury contribute substantially to secondary brain damage and neurodegeneration. Diverse inflammatory cascades such as pro-inflammatory cytokine secretion of invading leukocytes and direct cell-cell-contact cytotoxicity between lymphocytes and neurons have been demonstrated to mediate the inflammatory ‘collateral damage’ in models of acute brain injury. Besides mediating neuronal cell loss and degeneration, secondary inflammatory mechanisms also contribute to functional modulation of neurons and the impact of post-lesional neuroinflammation can even be detected on the behavioral level. The contribution of several specific immune cell subpopulations to the complex orchestration of secondary neuroinflammation has been revealed just recently. However, the differential vulnerability of specific neuronal cell types and the molecular mechanisms of inflammatory neurodegeneration are still elusive. Furthermore, we are only on the verge of characterizing the control of long-term recovery and neuronal plasticity after brain damage by inflammatory pathways. Yet, a more detailed but also comprehensive understanding of the multifaceted interaction of these two supersystems is of direct translational relevance. Immunotherapeutic strategies currently shift to the center of translational research in acute CNS lesion since all clinical trials investigating direct neuroprotective therapies failed. To advance our knowledge on brain-immune communications after brain damage an interdisciplinary approach covered by cellular neuroscience as well as neuroimmunology, brain imaging and behavioral sciences is crucial to thoroughly depict the intricate mechanisms.
Handbook Of Imaging In Multiple Sclerosis
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Author : Dejan Jakimovski
language : en
Publisher: Elsevier
Release Date : 2024-11-29
Handbook Of Imaging In Multiple Sclerosis written by Dejan Jakimovski and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-29 with Medical categories.
Handbook of Imaging in Multiple Sclerosis provides an up-to-date introduction into multiple sclerosis disease, including new findings on the pathophysiological processes, the clinical presentation, diagnosis, and treatment of the disease. This book includes in-depth chapters exploring the use of conventional and non-conventional imaging methods. These chapters cover magnetic resonance imaging (MRI) specific topics such as measurement of brain atrophy and susceptibility-weighted imaging. Additional chapters explore the use of additional imaging methods such as positron emission tomography (PET), optical coherence tomography (OCT) and high field MRI (use of 7T MRI scanners). - Reviews all non-conventional imaging modalities currently developed in the field of multiple sclerosis - Written by an international list of authors that are very highly regarded in the very specific field of their respective chapter - Includes information regarding the basics of acquisition and analysis that would allow researchers set-up their own MRI research
Crosstalk Between Peripheral And Local Immune Response In The Pathophysiology Of Stroke And Neurodegeneration Diseases
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Author : Yuanjian Fang
language : en
Publisher: Frontiers Media SA
Release Date : 2023-12-27
Crosstalk Between Peripheral And Local Immune Response In The Pathophysiology Of Stroke And Neurodegeneration Diseases written by Yuanjian Fang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-27 with Medical categories.
Neuroinflammation And Neurodegenerative Diseases
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Author : Pradeep Kumar
language : en
Publisher: Frontiers Media SA
Release Date : 2025-02-27
Neuroinflammation And Neurodegenerative Diseases written by Pradeep Kumar and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-02-27 with Science categories.
Neuroinflammation is a crucial area of study that has garnered increasing attention in recent years due to its implications in various neurodegenerative conditions, such as Alzheimer's disease, Parkinson's disease, multiple sclerosis, and amyotrophic lateral sclerosis. This Research Topic aims to delve into the intricate relationship between neuroinflammation and the pathogenesis of these neurodegenerative diseases, with a primary focus on identifying novel therapeutic interventions that could mitigate or halt disease progression. Despite considerable research progress in the field of neurodegenerative diseases, the exact underlying mechanisms and triggers remain partially understood. There is mounting evidence suggesting that neuroinflammation plays a critical role in the development and progression of these disorders. Immune-mediated inflammatory responses within the central nervous system can exacerbate neuronal damage, propagate neurodegeneration, and contribute to disease complexity. Understanding the precise interplay between neuroinflammation and neurodegenerative processes is of utmost importance for devising targeted therapies.
Multiple Sclerosis And Associated Demyelinating Disorders An Issue Of Neuroimaging Clinics Of North America E Book
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Author : Frederik Barkhof
language : en
Publisher: Elsevier Health Sciences
Release Date : 2024-07-01
Multiple Sclerosis And Associated Demyelinating Disorders An Issue Of Neuroimaging Clinics Of North America E Book written by Frederik Barkhof and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-07-01 with Science categories.
In this issue of Neuroimaging Clinics, guest editors Drs. Frederik Barkhof and Yaou Liu bring their considerable expertise to the topic of Multiple Sclerosis and Associated Demyelinating Disorders. Top experts in the field discuss advanced brain imaging in CNS demyelinating diseases; new imaging markers in MS and related disorders: smoldering inflammation and central vein sign; the use of AI in MS and white matter disease; optic nerve imaging in MS and related disorders; atypical demyelinating disorders; and more. Co-Editor Frederik Barkhof, MD, has received the National Multiple Sclerosis Society and the American Academy of Neurology's 2018 John Dystel Prize for Multiple Sclerosis Research for his many years of outstanding research in the field of MS, especially in advancing the understanding and clinical use of brain imaging. - Contains 12 relevant, practice-oriented topics including diagnostic criteria for MS, NMOSD and MOGAD; routine MRI protocol and standardization in CNS demyelinating diseases; spinal cord imaging in MS and related disorders; treatment monitoring in MS: efficacy and safety; cognitive impairment in MS and related disorders; and more. - Provides in-depth clinical reviews on multiple sclerosis and associated demyelinating disorders, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.