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Ghrelin In Health And Disease


Ghrelin In Health And Disease
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Ghrelin In Health And Disease


Ghrelin In Health And Disease
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Author : Roy G. Smith
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-10-19

Ghrelin In Health And Disease written by Roy G. Smith and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-19 with Medical categories.


Ghrelin, the endogenous ligand for the growth hormone secretagogue (GHS) receptor, is critical in the control of food intake and energy balance. The ghrelin receptors are now known to have important physiological properties as modulators of growth hormone release, appetite, glucose homeostasis, metabolism, immune function, neurotransmitter activity, cognitive function and neurodegeneration. Bringing all of this information together in the first comprehensive text on the topic, Ghrelin in Health and Disease provides a state-of-the-art synthesis of the latest work in this area for physicians and physician-scientists. This volume addresses the unique property of ghrelin as a modulator of function. Such a property provides potential utility for safe intervention in a wide variety of disease states. Indeed as we learn more about the basic physiology of ghrelin, the potential for treating new disease targets emerge requiring validation in the clinic. Each chapter in this volume is authored by a leading investigator in the field. The introductory chapter sets the background for the book and provides a superb overview of the relevance of ghrelin to physiology, describing how the discovery of ghrelin has prompted us to completely rethink traditional physiology. The authors conclude their chapters by critically addressing the future translational aspects of ghrelin biology and outlining what key basic research and clinical questions remain to be addressed. An invaluable resource, Ghrelin in Health and Disease distinguishes itself as the first comprehensive title covering all of the molecular and clinical issues relating to ghrelin and advancing our clinical understanding of obesity, growth, and reproductive pathogenesis.



Ghrelin Function Mechanism Of Action And Role In Health And Disease


Ghrelin Function Mechanism Of Action And Role In Health And Disease
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Author : Dennis Hertz
language : en
Publisher:
Release Date : 2020-03-30

Ghrelin Function Mechanism Of Action And Role In Health And Disease written by Dennis Hertz and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-30 with categories.


Ghrelin is a 28-amino acid peptide mainly secreted by the stomach. To better understand the role of ghrelin signaling, Ghrelin: Function, Mechanism of Action and Role in Health and Disease first explores the regulation of age-associated adipose tissue inflammation. Following this, the authors discuss the influence of different variables on the response of short-term appetite regulation induced by exercise. External factors such as temperature and environment exert effects on hormonal responses, including hunger sensation and energy intake. The effects of gender differences and aging on psychological stress-dependent eating disorders are assessed, and the involvement of endogenous ghrelin, the serotonin 2c receptor and the estrogen alpha receptor is discussed. The penultimate chapter reviews the relationship between sleep and eating behavior, focusing in the influences of circadian changes on appetite related responses such as plasma concentration of ghrelin. The concluding study highlights the ghrelin system as a promising candidate for cardiovascular drug discovery, a new therapeutic approach for the treatment of endothelial impairment, and a possible contribution to the prevention of atherosclerosis.



Ghrelin Motilin In Health And Disease


Ghrelin Motilin In Health And Disease
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Author : E. Z. H. Sung
language : en
Publisher:
Release Date : 2012

Ghrelin Motilin In Health And Disease written by E. Z. H. Sung and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with categories.




Ghrelin


Ghrelin
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Author : Ezio Ghigo
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-04-11

Ghrelin written by Ezio Ghigo and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-11 with Medical categories.


Ghrelin is a 28-amino acid acylated peptide predominatntly produced by the stomach. Highlights the impact and function of the hormone ghrelin and provides insight to neuroendocrinologies and researchers interested in its molecular and clinical relevance.



Integrative Review Of Ghrelin Family Peptides Musculoskeletal Health And Osteoporotic Fractures


Integrative Review Of Ghrelin Family Peptides Musculoskeletal Health And Osteoporotic Fractures
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Author : Leon Fisher
language : en
Publisher: Cambridge Scholars Publishing
Release Date : 2024-04-23

Integrative Review Of Ghrelin Family Peptides Musculoskeletal Health And Osteoporotic Fractures written by Leon Fisher and has been published by Cambridge Scholars Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-23 with Medical categories.


This book describes multiple effects of four stomach derived hormones (acylated and unacylated ghrelin, obestatin and nesfatin-1) collectively known as ghrelin family peptides (GFPs). The first part of the book focuses on known actions of GFPs under normal physiological conditions. Subsequent chapters describe the role of dysregulation in the production and action of these peptides in the complex network involved in numerous chronic diseases, musculoskeletal health, osteoporosis, falls and, consequently, osteoporotic fractures. The emerging data on the potential diagnostic and therapeutic benefits of GFPs in different disorders and implications on clinical practice is presented, and an extensive bibliography is provided.



Growth Hormone In Health And Disease


Growth Hormone In Health And Disease
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Author :
language : en
Publisher: Academic Press
Release Date : 2016-02-03

Growth Hormone In Health And Disease written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-02-03 with Science categories.


This volume of Progress in Molecular Biology and Translational Science focuses on the growth hormone in health and disease. Contributions from leading authorities Informs and updates on all the latest developments in the field



Molecular Basis Of Health And Disease


Molecular Basis Of Health And Disease
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Author : Undurti N. Das
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-04-02

Molecular Basis Of Health And Disease written by Undurti N. Das and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-02 with Medical categories.


The book describes how the balance between pro- and anti-inflammatory molecules is related to health and disease. It is suggested that many diseases are initiated and their progress is influenced by inflammatory molecules and a decrease in the production and/or action of anti-inflammatory molecules and this imbalance between pro- and anti-inflammatory molecules seems to have been initiated in the perinatal period. This implies that strategies to prevent and manage various adult diseases should start in the perinatal period. An alteration in the metaolism of essential fatty acids and their anti-inflammatory molecules such as lipoxins, resolvins, protecitns, maresins and nitrolipids seems to play a major role in the pathobiology of several adult diseases. Based on these concepts, novel therapeutic approaches in the management of insulin resistance, obesity, type 2 diabetes mellitus, metabolic syndrome, cancer, lupus, rheumatoid arthritis and other auto-immune diseases are presented. Based on all these evidences, a unified concept that several adult diseases are due to an alteration in the balance between pro- and anti-inflammatory molecules is discussed and novel methods of their management are presented.



The Ghrelin System


The Ghrelin System
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Author : A. Benso
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2013-04-22

The Ghrelin System written by A. Benso and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-22 with Medical categories.


The ghrelin story started more than 30 years ago with the discovery of synthetic GH secretagogues. Only in 1999 was ghrelin‚ a natural GH-releasing peptide, discovered. Ghrelin, however, is much more than simply a natural GH secretagogue. In fact, this hormone is one of the most important factors known for regulating appetite and energy expenditure. Furthermore, ghrelin is the trigger for other neuroendocrine, metabolic and nonendocrine actions.This book, written by researchers who provided the major contributions to our current knowledge of this complex system, gives a comprehensive overview of the recent advances in ghrelin research. The hormone's influence on the cardiovascular, metabolic and gastroenteropancreatic system, hypothalamus-pituitary-adrenal axis, prolactin secretion, thyroid axis, gonadal axis as well as on behavior is discussed in detail. Furthermore, the clinical perspectives for ghrelin-derived therapeutic products are presented.Illustrating the tight inter-relationship between endocrinology, metabolism, cardiovascular disease and internal medicine, this book is essential reading for all scientists interested in appetite control, body weight and energy expenditure, as well as diabetes mellitus and neuroendocrinology.



Global Perspectives On Childhood Obesity


Global Perspectives On Childhood Obesity
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Author : Debasis Bagchi
language : en
Publisher: Academic Press
Release Date : 2010-10-12

Global Perspectives On Childhood Obesity written by Debasis Bagchi and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-10-12 with Medical categories.


Understanding the complex factors contributing to the growing childhood obesity epidemic is vital not only for the improved health of the world's future generations, but for the healthcare system. The impact of childhood obesity reaches beyond the individual family and into the public arenas of social systems and government policy and programs. Global Perspectives on Childhood Obesity explores these with an approach that considers the current state of childhood obesity around the world as well as future projections, the most highly cited factors contributing to childhood obesity, what it means for the future both for children and society, and suggestions for steps to address and potentially prevent childhood obesity. This book will cover the multi-faceted factors contributing to the rapidly growing childhood obesity epidemic The underlying causes and current status of rapidly growing obesity epidemic in children in the global scenario will be discussed The strategies for childhood obesity prevention and treatment such as physical activity and exercise, personalized nutrition plans and school and community involvement will be presented



Gut Hormones


Gut Hormones
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Author : Stephen Robert Bloom
language : en
Publisher:
Release Date : 1981

Gut Hormones written by Stephen Robert Bloom and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981 with Gastrointestinal hormones categories.