Glycosylation
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Fundamentals Of Glycosylation
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Author : Alok Raghav
language : en
Publisher: BoD – Books on Demand
Release Date : 2022-01-26
Fundamentals Of Glycosylation written by Alok Raghav and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-26 with Science categories.
The diverse phenomenon of post-translational modifications of biological macromolecules (proteins, lipids, and nucleic acids) includes phosphorylation, glycosylation, ubiquitination, nitrosylation, methylation, acetylation, lipidation, and proteolysis. The mechanism of protein glycosylation has an important role in the regulation of human health. This book identifies the fundamentals of glycosylation that help in understanding the concepts of protein glycosylation and its significance.
Protein Glycosylation
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Author : Roslyn M. Bill
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Protein Glycosylation written by Roslyn M. Bill and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Protein Glycosylation provides clear, up-to-date, and integrated coverage of key topics in this field. Particular emphasis is placed on the biosynthetic pathways that result in a wide variety of identified protein-bound oligosaccharides. Protein Glycosylation begins with an overview of the chemical structures of mono- and oligosaccharides, to provide a scientific basis for the later chapters. The book includes discussions on the purification, function, and enzyme kinetics of selected glycosidases and glycotransferases, as well as a review of the roles of oligosaccharides in glycoprotein function and the in vivo role of glycoproteins themselves. Finally, the in vitro synthesis of glycoproteins is presented, together with future directions in glycobiology. Protein Glycosylation serves as an excellent text for upper-level undergraduate and graduate students as well as a reference for those scientists whose training is not in glycobiology but who are moving into this field.
Glycosylation
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Author : Stefana Petrescu
language : en
Publisher: BoD – Books on Demand
Release Date : 2012-09-26
Glycosylation written by Stefana Petrescu and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-09-26 with Science categories.
This book, outlining the concepts of glycobiology, is a suite of reviews and articles written by a team of acknowledged researchers and covers some of the key topics in the field. Covering a wide range of theoretical and practical issues in the field of glycobiology, the Glycosylation book will be of an immediate value for students, academics and researchers involved in drug glycoengineering and biomedical research.
The Role Of Glycosylation In Health And Disease
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Author : Gordan Lauc
language : en
Publisher: Springer Nature
Release Date : 2021-09-08
The Role Of Glycosylation In Health And Disease written by Gordan Lauc and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-08 with Science categories.
Glycobiology is an emerging field of studying glycans (sugars) and glycoconjugates that are essentially involved in almost all biological processes, from fine-tuning glycoprotein function to protein-protein interactions, signaling, immune response, host-pathogen interactions, etc. However, due to structural complexity of glycans and analytical challenges this exciting field was lagging behind other areas of biology. With technological advancements growing number of glycans’ functions are being discovered and the study of glycans is becoming a cutting-edge discipline in basic and clinical research. Despite recent developments in glycobiology field, many aspects of glycosylation process still remain unknown, both in a healthy human organism and in pathological states. Human glycome is dynamic and changes with physiological triggers, immune challenges and disease. Atypical glycosylation is consequently a subject of disease biomarker research, and a target for therapeutic interventions. On the other hand, properties of glycosylated biotherapeutics are predominantly determined by their glycans. The Role of Glycosylation in Health and Disease provides a comprehensive overview of types and functions of glycans in a healthy human organism as well as their role in pathophysiology of different diseases and efficiency of glycosylated biotherapeutics. Written by the experts in the field, this book aims to bring glycobiology field closer to students, researchers in life sciences and professionals in biopharmaceutical industry.
Protein Glycosylation Advances In Identification Characterization And Biological Function Elucidation Using Mass Spectrometry
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Author : Ganglong Yang
language : en
Publisher: Frontiers Media SA
Release Date : 2022-03-14
Protein Glycosylation Advances In Identification Characterization And Biological Function Elucidation Using Mass Spectrometry written by Ganglong Yang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-14 with Science categories.
Diabetes And Protein Glycosylation
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Author : Margo Panush Cohen
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Diabetes And Protein Glycosylation written by Margo Panush Cohen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
In the years since the initial discovery that blood from diabetic patients contains increased amounts of a posttranslationally gluco sylated form of hemoglobin (hemoglobin Ale)' an impressive number of studies have clarified and expanded the use of glycohemoglobin levels to assess disease status. Many other structural proteins have been shown to undergo similar changes, including proteins from tissues most commonly affected in diabetes (e.g., lens, aorta, peripheral nerve, basement membrane). Thus, the nonenzymatic glycosylation of hemoglobin emerges as an invaluable model for the pathogenesis of certain chronic diabetes complications. In addition to reviewing a wealth of investigative possibilities in the area of these chronic complications-including eye, kidney, nerve, and vascular disease-Dr. Cohen indicates how enhanced nonenzymatic glycosylation in uncontrolled diabetes underscores the pressing need for maintenance of long-term euglycemia. Dr. Cohen is an endocrinologist and diabetes specialist whose research activities have largely focused on the chemistry and metabo lism of the basement membrane in diabetes. This superb monograph on nonenzymatic glycosylation clearly shows the major trends of her past and present research and clinical activities. This book is beautifully written and a pleasure to read. It provides great insight into the mechanisms of the pathogenesis of the oom- vii viii Foreword cations of diabetes and should be of immense value not only to basic and clinical investigators, but also to internists, diabetologists, and endocrinologists in clinical practice.
Protein Glycosylation
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Author : Harald S. Conradt
language : en
Publisher:
Release Date : 1991
Protein Glycosylation written by Harald S. Conradt and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Science categories.
Glycosylation And Cancer
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Author :
language : en
Publisher: Academic Press
Release Date : 2015-02-26
Glycosylation And Cancer written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-02-26 with Science categories.
Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics. Provides information on cancer research Outstanding and original reviews Suitable for researchers and students
Glycosylation
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Author : Mohammed Al-Rubeai
language : en
Publisher: Springer
Release Date : 2002-06-30
Glycosylation written by Mohammed Al-Rubeai and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-06-30 with Science categories.
The analysis and modification of glycans of recombinant proteins continues to be active and challenging area of research and for the successful manufacture of these proteins. In Cell Engineering, volume 3: Glycosylation, Dr. Mohammed Al-Rubeai has compiled a group of articles that will provide research workers not only with reviews of the advances that have been made in all facets of the subject but with an in-depth assessment of the state of the art methodology and the various approaches for the improvement of glycoprotein production. Particularly important in this respect is the advances made in the development of genetically engineered host cell lines with novel glycosylation properties, as well as the integration of mass spectrophotometric analysis with separation techniques. This volume is intended not only for research students and senior scientists in cell culture and glycobiology, but also for industrial biotechnologists and biochemical engineers interested in the production of therapeutic glycoproteins, virus vector and ex vivo expansion of human cells for medical treatment.
Glycosylation
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Author : Gavin P. Davey
language : en
Publisher: Humana
Release Date : 2022-10-07
Glycosylation written by Gavin P. Davey and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-07 with Science categories.
This volume explores the latest techniques and methods used for performing up-to-date glycosylation research. The chapters in this book are organized into four parts. Part One looks at the latest analytical and bioinformatics technologies that enable the characterization of glycosylation complexity. Part Two details the importance of synthetic chemistry and glycoengineering in the fields of bioprocessing and biotherapeutic development. Part Three discusses systems biology and computational technologies used by scientists to analyze glycosylation events in the cell. Part Four focuses on how cellular glycosylation biomarkers can be identified and used to characterize human clinical datasets. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Glycosylation: Methods and Protocols is a valuable resource for any scientist or researcher interested in learning more about this exciting and developing field.