Governing Molecules
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Governing Molecules
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Author : Herbert Gottweis
language : en
Publisher: MIT Press
Release Date : 1998-12-10
Governing Molecules written by Herbert Gottweis and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-12-10 with Technology & Engineering categories.
Scientists, investors, policymakers, the media, and the general public have all displayed a continuing interest in the commercial promise and potential dangers of genetic engineering. In this book, Herbert Gottweis explains how genetic engineering became so controversial—a technology that some seek to promote by any means and others want to block entirely. Beginning with a clear exposition of poststructuralist theory and its implications for research methodology, Gottweis offers a novel approach to political analysis, emphasizing the essential role of narratives in the development of policy under contemporary conditions. Drawing on more than eighty in-depth interviews and extensive archival work, Gottweis traces today's controversy back to the sociopolitical and scientific origins of molecular biology, paying particular attention to its relationship to eugenics. He argues that over the decades a number of mutually reinforcing political and scientific strategies have attempted to turn genes into objects of technological intervention—to make them "governable." Looking at critical events such as the 1975 Asilomar conference in the United States, the escalating conflict in Germany, and regulatory disputes in Britain and France during the 1980s, Gottweis argues that it was the struggle over boundaries and representations of genetic engineering, politics, and society that defined the political dynamics of the drafting of risk regulations in these countries. In a key chapter on biotechnology research, industry, and supporting technology policies, Gottweis demonstrates that the interpretation of genetic engineering as the core of a new "high technology" industry was part of a policy myth and an expression of identity politics. He suggests that under postmodern conditions a major strategy for avoiding policy failure is to create conditions that ensure tolerance and respect for the multiplicity of socially available policy narratives and reality interpretations.
Governing Molecules
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Author : Herbert Gottweis
language : en
Publisher: Mit Press
Release Date : 1998
Governing Molecules written by Herbert Gottweis and has been published by Mit Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Political Science categories.
Herbert Gottweis explains how genetic engineering became so controversial. Beginning with an exposition of poststructuralist theory and its implications for research methodology, he approaches political analysis, emphasizing the essential role of narratives in the development of policy.
Genetic And Epigenetic Control On Immune Responses Regulating Molecules In Cancer Development Progression And Treatment
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Author : Katherine Chiappinelli
language : en
Publisher: Frontiers Media SA
Release Date : 2021-11-30
Genetic And Epigenetic Control On Immune Responses Regulating Molecules In Cancer Development Progression And Treatment written by Katherine Chiappinelli and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-30 with Medical categories.
Protein Conformational Dynamics
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Author : Ke-li Han
language : en
Publisher: Springer Science & Business Media
Release Date : 2014-01-20
Protein Conformational Dynamics written by Ke-li Han and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-20 with Medical categories.
This book discusses how biological molecules exert their function and regulate biological processes, with a clear focus on how conformational dynamics of proteins are critical in this respect. In the last decade, the advancements in computational biology, nuclear magnetic resonance including paramagnetic relaxation enhancement, and fluorescence-based ensemble/single-molecule techniques have shown that biological molecules (proteins, DNAs and RNAs) fluctuate under equilibrium conditions. The conformational and energetic spaces that these fluctuations explore likely contain active conformations that are critical for their function. More interestingly, these fluctuations can respond actively to external cues, which introduces layers of tight regulation on the biological processes that they dictate. A growing number of studies have suggested that conformational dynamics of proteins govern their role in regulating biological functions, examples of this regulation can be found in signal transduction, molecular recognition, apoptosis, protein / ion / other molecules translocation and gene expression. On the experimental side, the technical advances have offered deep insights into the conformational motions of a number of proteins. These studies greatly enrich our knowledge of the interplay between structure and function. On the theoretical side, novel approaches and detailed computational simulations have provided powerful tools in the study of enzyme catalysis, protein / drug design, protein / ion / other molecule translocation and protein folding/aggregation, to name but a few. This work contains detailed information, not only on the conformational motions of biological systems, but also on the potential governing forces of conformational dynamics (transient interactions, chemical and physical origins, thermodynamic properties). New developments in computational simulations will greatly enhance our understanding of how these molecules function in various biological events.
Molecular Encapsulation
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Author : Udo H. Brinker
language : en
Publisher: John Wiley & Sons
Release Date : 2011-07-07
Molecular Encapsulation written by Udo H. Brinker and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-07-07 with Science categories.
The inclusion of small guest molecules within suitable host compounds results in constrained systems that imbue novel properties upon the incarcerated organic substrates. Supramolecular tactics are becoming widely employed and this treatise spotlights them. Often, the impact of encapsulation on product formation is substantial. The use of constrained systems offers the means to steer reactions along desired pathways. A broad overview of various supramolecular approaches aimed to manipulate chemical reactions are featured. The following topics are covered in detail: - general concepts governing the assembly of the substrate with the reaction vessel - preparation of molecular reactors - stabilization of reactive intermediates - reactions in water, in organic solvents, and in the solid state - photochemical reactions - reactions with unusual regioselectivity Molecular Encapsulation: Organic Reactions in Constrained Systems is an essential guide to the art of changing the outcome and the selectivity of a chemical reaction using nano-sized reaction vessels. It will find a place on the bookshelves of students and researchers working in the areas of supramolecular chemistry, nanotechnology, organic and pharmaceutical chemistry, and materials science as well.
Novel Plant Molecules Regulating The Interaction With Pathogenic And Beneficial Fungi
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Author : Silvia Proietti
language : en
Publisher: Frontiers Media SA
Release Date : 2021-03-26
Novel Plant Molecules Regulating The Interaction With Pathogenic And Beneficial Fungi written by Silvia Proietti and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-26 with Science categories.
Molecular Life Sciences
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Author : Robert D. Wells
language : en
Publisher: Springer
Release Date : 2018-01-12
Molecular Life Sciences written by Robert D. Wells and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-12 with Science categories.
Molecular Life Sciences: An Encyclopedic Reference will focus on understanding biological phenomena at the level of molecules and their interactions that govern life processes. The work will include articles on genes and genomes, protein structure and function, systems biology using genomics and proteomics as the focus, molecular aspects of cell structure and function, unifying concepts and theories from biology, chemistry, mathematics and physics that are essential for understanding the molecular life sciences (including teaching perspectives and assessment tools), and basic aspects of the various experimental approaches that are used in the Molecular Life Sciences.
A Pictorial Approach To Molecular Bonding
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Author : John G. Verkade
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
A Pictorial Approach To Molecular Bonding written by John G. Verkade and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
With the development of accurate molecular calculations in recent years, useful predictions of molecular electronic properties are currently being made. It is therefore becoming increasingly important for the non-theoretically oriented chemist to appreciate the underlying principles governing molecular orbital formation and to distinguish them from the quantitative details as sociated with particular molecules. It seems highly desirable then that the non theoretician be able to deduce results of general validity without esoteric mathematics. In this context, pictorial reasoning is particularly useful. Such an approach is virtually indispensable if bonding concepts are to be taught to chemistry students early in their careers. Undergraduate chemistry majors typically find it difficult to formulate molecular orbital schemes, especially delocalized ones, for molecules more complicated than diatomics. The major reason for this regrettable situation is the general impracticability of teaching group theory before students take organic and inorganic courses, wherein the applications of these concepts are most beneficial. Consequently many students graduate with the misconcep tion that the ground rules governing bonding in molecules such as NH3 are somehow different from those which apply to aromatic systems such as C H • 6 6 Conversely, seniors and many graduate students are usually only vaguely, if at all, aware that sigma bonding (like extended pi bonding) can profitably be described in a delocalized manner when discussing the UV-photoelectron spectrum of CH , for example.
Biology Computing And The History Of Molecular Sequencing
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Author : M. García-Sancho
language : en
Publisher: Springer
Release Date : 2012-05-11
Biology Computing And The History Of Molecular Sequencing written by M. García-Sancho and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-05-11 with Science categories.
Sequencing is often associated with the Human Genome Project and celebrated achievements concerning the DNA molecule. However, the history of this practice comprises not only academic biology, but also the world of computer-assisted information management. The book uncovers this history, qualifying the hype and expectations around genomics.
Problem Solving In Computational Molecular Science
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Author : Stephen Wilson
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Problem Solving In Computational Molecular Science written by Stephen Wilson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
For all practical purposes the basic physical equations governing the behaviour of a system at the molecular level can only be solved approximately. The key issue in any reliable and accurate computational study in molecular physics and quantum chemistry is the adoption of a suitable model which contains the essential physics and chemistry, is computationally tractable, and preferably amenable to systematic refinement. The provision of advice on the choice of an appropriate model for a specific problem has so far received scant attention. This issue is becoming acute as `standard' software packages are becoming widely available and are being increasingly heavily used in both the academic and industrial sectors by researchers who have received no special training in the theoretical physics and chemistry that underpins them. This volume provides researchers whose background may not be in the computational molecular sciences with the necessary background to make intelligent use of the methods available by performing reliable calculations of appropriate accuracy and making a considered interpretation of the data so obtained.