Immune Microenvironment And Immunotherapy In Malignant Brain Tumors
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Immune Microenvironment And Immunotherapy In Malignant Brain Tumors
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Author : Liangxue Zhou
language : en
Publisher: Frontiers Media SA
Release Date : 2023-12-19
Immune Microenvironment And Immunotherapy In Malignant Brain Tumors written by Liangxue Zhou and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-19 with Medical categories.
The Interconnection Between The Tumor Microenvironment And Immunotherapy In Brain Tumors
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Author : Quan Cheng
language : en
Publisher: Frontiers Media SA
Release Date : 2023-06-08
The Interconnection Between The Tumor Microenvironment And Immunotherapy In Brain Tumors written by Quan Cheng and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-08 with Medical categories.
Immunotherapy For Tumor In The Brain Insights From And For Other Tumor Sites
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Author : Lois A. Lampson
language : en
Publisher: Frontiers Media SA
Release Date : 2018-07-09
Immunotherapy For Tumor In The Brain Insights From And For Other Tumor Sites written by Lois A. Lampson and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-09 with categories.
Tumor immunotherapy has now shown its promise for many, its disappointments and failings for others. Going forward, brain tumor patients can both benefit and contribute. Tumor immunotherapy is steadily progressing. As experience accumulates, it is important to consider its generality. The reviews herein emphasize the brain’s place among other tumor sites. Two major topics are addressed. THE SITE: WHAT CAN WE EXPECT FROM IMMUNOTHERAPY WHEN THE TARGET IS IN THE BRAIN? Experience with immunotherapy for different targets in the brain, including tumor and also pathogens, is reviewed. Long-standing assumptions are confronted. The potential for beneficial responses is stressed. BRAIN TUMOR IMMUNOTHERAPY: WHAT HAVE WE LEARNED SO FAR? Clinical experience with brain tumor immunotherapy, from a variety of centers, is reviewed. Primary tumors, emphasizing glioblastoma, and brain metastases are each considered.
The Immunology And Biology Of Brain Tumors
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Author : Michael Graner
language : en
Publisher: MDPI
Release Date : 2021-05-04
The Immunology And Biology Of Brain Tumors written by Michael Graner and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-04 with Medical categories.
Immunotherapy has become a viable treatment modality for a variety of cancers (and referred to as Science Magazine’s “Breakthrough of the Year” in 2013, as well as ASCO’s “Advance of the Year” in both 2016 and 2017). This Special Issue is focused on the relevance of immunobiology in brain tumors, touching on elements of immune suppression, immune stimulation, and the immune microenvironment, with culminations in translational immunotherapy.
Brain Tumor Immunotherapy
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Author : Linda M. Liau
language : en
Publisher: Springer Science & Business Media
Release Date : 2000-11-10
Brain Tumor Immunotherapy written by Linda M. Liau and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-11-10 with Medical categories.
An authoritative panel of researchers and clinicians critically reviews the entire field to provide a comprehensive guide to modern brain tumor immunotherapy and thereby enhance future research in this area. The contributors detail many of the key laboratory experiments and clinical protocols that are currently being investigated, integrate the available information from previous and ongoing research, and help define the current status of the field. Topics range from adoptive cellular and antibody-mediated immunotherapy of brain tumors to tumor vaccines and related strategies, and include many vanguard experimental strategies and immunological techniques for studying brain tumor immunotherapy. Cutting-edge and comprehensive, Brain Tumor Immunotherapy brings together all the important recent advances in our understanding of central nervous system tumor immunology and illustrates in powerful detail the many new applications now harnessing the immune response for brain tumor therapeutics.
Immunotherapeutic Strategies For The Treatment Of Glioma
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Author : Christopher Jackson
language : en
Publisher: Academic Press
Release Date : 2021-09-10
Immunotherapeutic Strategies For The Treatment Of Glioma written by Christopher Jackson and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-10 with Science categories.
Immunotherapeutic Strategies for the Treatment of Glioma provides a review of the current state of immunotherapy for primary brain tumors. The topic is of interest to patients, clinicians, and researchers alike, particularly given the recent failure of large clinical trials. This book serves as an overview of the most promising approaches in the field and provides a foundation for considering novel and combination therapies moving forward. The book discusses several types of immunotherapies for glioma, such as peptide, dendritic cell and heat shock protein vaccines; immune checkpoint blockade; myeloid cells as target; oncolytic viruses; and CAR T cell therapy. Additionally, it discusses the mechanisms of immune suppression in patients and immunogenomics. This volume is a valuable source for cancer researchers, oncologists and several members of biomedical field who are interested in novel strategies to fight glioblastoma. Summarizes the work in immunotherapy for glioma to-date, including the available evidence from preclinical studies and clinical trials Reviews the challenges and successes of the most promising strategies for brain tumor immunotherapy Provides a foundation for considering novel and combination therapies moving forward
Translational Immunotherapy Of Brain Tumors
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Author : John H. Sampson
language : en
Publisher: Academic Press
Release Date : 2017-02-06
Translational Immunotherapy Of Brain Tumors written by John H. Sampson and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-06 with Science categories.
Translational Immunotherapy of Brain Tumors gives researchers and practitioners an up-to-date and comprehensive overview of the field. Chapters include adoptive immunotherapy, immunosuppression, CAR therapy of brain tumors, and dendritic cell therapy for brain tumors. Very few agents have been shown to be efficacious in the treatment of malignant gliomas. Recently, there have been a number of studies demonstrating the potential success of immunotherapy for brain tumors. Immunotherapeutics are becoming the most frequent drugs to be used in cancer therapy. These new breakthroughs, now approved by the FDA, are a part of multiple phase III international trials and ongoing research in malignant glioma, meaning that the information in this cutting-edge book will be of great importance to practitioners and researchers alike. Comprehensive overview, providing an update on immunology, translational immunotherapy, and clinical trials relating to malignant gliomas Edited by a prominent neurosurgeon with contributions by leading researchers in the field Ideal resource for researchers and practitioners interested in learning about mechanisms that use the immune system to treat brain tumors
Impact Of The Glioma Microenvironment On Antitumor Immunity
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Author : Valérie Dutoit
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-31
Impact Of The Glioma Microenvironment On Antitumor Immunity written by Valérie Dutoit and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-31 with Medical categories.
Tumor Immunology And Immunotherapy Integrated Methods Part B
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Author :
language : en
Publisher: Academic Press
Release Date : 2020-04-01
Tumor Immunology And Immunotherapy Integrated Methods Part B written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-01 with Science categories.
Tumor Immunology and Immunotherapy - Integrated Methods Part B, Volume 636 in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this update include Quantification methods of Transforming Growth Factor beta (TGF??) activity in the setting of cancer immunotherapy, Decoding cancer cell death-driven immune cell recruitment: An in vivo method for site-of-vaccination analyses, Tracking and interrogating tissue-resident and recruited microglia in brain tumors, Metabolomics and lipidomics of the tumor microenvironment, Monitoring abscopal responses to radiation in mice, and much more. Provides an array of authors who are authorities in the field Presents comprehensiveness coverage of the topics Includes a broad level of detail and in-depth coverage
Tumor Microenvironment
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Author : Peter P. Lee
language : en
Publisher: Springer Nature
Release Date : 2020-03-25
Tumor Microenvironment written by Peter P. Lee and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-25 with Medical categories.
This book addresses the biological processes relevant to the immune phenotypes of cancer and their significance for immune responsiveness, based on the premise that malignant cells manipulate their surroundings through an evolutionary process that is controlled by interactions with innate immune sensors as well as the adaptive recognition of self/non-self. Checkpoint inhibitor therapy is now an accepted new form of cancer treatment. Other immuno-oncology approaches, such as adoptive cell therapy and metabolic inhibitors, have also shown promising results for specific indications. Immune resistance is common, however, limiting the efficacy of immunotherapy in many common cancer types. The reasons for such resistance are diverse and peculiar to the immune landscapes of individual cancers, and to the treatment modality used. Accordingly, approaches to circumvent resistance need to take into account context-specific genetic, biological and environmental factors that may affect the cancer immune cycle, and which can best be understood by studying the target tissue and correlated systemic immune markers. Understanding the major requirements for the evolutionary process governing human cancer growth in the immune-competent host will guide effective therapeutic choices that are tailored to the biology of individual cancers.