Inorganic Biochemistry Of Iron Metabolism


Inorganic Biochemistry Of Iron Metabolism
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Inorganic Biochemistry Of Iron Metabolism


Inorganic Biochemistry Of Iron Metabolism
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Author : Robert R. Crichton
language : en
Publisher: John Wiley & Sons
Release Date : 2001-10-17

Inorganic Biochemistry Of Iron Metabolism written by Robert R. Crichton and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-10-17 with Medical categories.


Iron is of fundamental importance for the growth, development and well being of almost all living organisms. Multiple biological systems have been developed for the uptake, utilisation, storage and homeostasis of iron in microbes, plants and mammals. e.g. Both iron deficiency and iron overload are found extensively in man: the intimate links between iron and oxidative stress are associated with a wide range of pathologies; iron has a well established role in infections by a wide range of microorganisms and parasites; there is a close link between iron requirements and cellular division with implications for cancers and other metals such as copper and zinc are closely linked with iron metabolism. The first edition of this book was published in 1991. Since then the extensive impact of molecular cell biology on the field of iron biochemistry has opened new horizons in our understanding of the transport and storage of iron and of its homeostasis. The explosive use of molecular biological techniques applied to cellular biology of iron metabolism has resulted in a rapid expansion in the literature which has led to the need for this second edition. This second edition also: Introduces many illustrations and colour photos to make the basic concepts far clearer Includes new chapters on iron and cell division and interactions of iron with other metals - particularly copper and zinc Provides additional anecdotes Incorporates an extensive and up-to-date bibliography



Inorganic Biochemistry Of Iron Metabolism


Inorganic Biochemistry Of Iron Metabolism
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Author : Robert R. Crichton
language : en
Publisher: Ellis Horwood
Release Date : 1991

Inorganic Biochemistry Of Iron Metabolism written by Robert R. Crichton and has been published by Ellis Horwood this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Medical categories.


Concentrates on the importance of iron in biology, emphasizing the need for well-defined amounts of iron for the survival, replication and differentiation of the cells of animals, plants and almost all micro-organisms.



Iron Metabolism


Iron Metabolism
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Author : Glória C. Ferreira
language : en
Publisher: John Wiley & Sons
Release Date : 2008-09-26

Iron Metabolism written by Glória C. Ferreira and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-09-26 with Science categories.


Iron plays a crucial role in many biochemical processes. In recent years intensive research has led to a better understanding of the function of iron in cellular metabolism. In more than twenty articles internationally renowned experts give a thorough account of the recent developments of this fascinating field. The book focuses on the central questions, e.g. transport, storage, and utilization of iron in cells, the three-dimensional structure of iron-containing proteins, the physiological function of heme and iron sulfur-containing proteins, and the regulatory mechanisms in heme biosynthesis and redox regulation of signal transduction. The interdisciplinary character of the book is designed to explore the many facets of the new findings and to provide a comprehensive overview of recent advances for biochemists, bioinorganic chemists, molecular biologists, microbiologists and immunologists. The reviews are supplemented with valuable background information, results and numerous references. This book emphasizes the relationships between the different disciplines concerned with iron metabolism and opens new perspectives for future research!



Inorganic Biochemistry Of Iron Metabolism


Inorganic Biochemistry Of Iron Metabolism
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Author : Robert Crichton
language : en
Publisher:
Release Date : 2003

Inorganic Biochemistry Of Iron Metabolism written by Robert Crichton and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with categories.


Iron is of fundamental importance for the growth, development and well being of almost all living organisms. Multiple biological systems have been developed for the uptake, utilisation, storage and homeostasis of iron in microbes, plants and mammals. e.g. Both iron deficiency and iron overload are found extensively in man: the intimate links between iron and oxidative stress are associated with a wide range of pathologies; iron has a well established role in infections by a wide range of microorganisms and parasites; there is a close link between iron requirements and cellular division with im.



Biochemistry Of Nonheme Iron


Biochemistry Of Nonheme Iron
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Author : Anatoly Bezkorovainy
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Biochemistry Of Nonheme Iron written by Anatoly Bezkorovainy and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.


Atomic biology has come of age. Interest in the role of chemical elements in life processes has captured the imagination of a wide spectrum of research scientists-ranging from the nutritionist to the biochemist, the inorganic chemist, and even to some biophysicists. This series, Biochemistry of the Elements, is a recognition of this increasing interest. When complete, the books will assemble the hard facts concerning the biochemistry of each element-singly or in a logical grouping. The series will provide a permanent reference for this active and growing field. Each volume shall represent an integrated effort by one or several authors to describe the current knowledge of an element(s) or the methods by which it is studied. Iron is the only element to which we have devoted two volumes, because its biological and chemical role is so versatile and complex. These two volumes will treat the two main structural categories of iron: heme and nonheme iron. In this volume on nonheme iron, the first in the series, Anatoly Bezkorovainy provides what we believe is the most comprehensive treatment of this important topic.



Iron Metabolism


Iron Metabolism
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Author : Robert Crichton
language : en
Publisher: John Wiley & Sons
Release Date : 2016-03-31

Iron Metabolism written by Robert Crichton and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-03-31 with Medical categories.


Iron is indispensable for the growth, development and well-being of almost all living organisms. Biological systems from bacteria, fungi and plants to humans have evolved systems for the uptake, utilisation, storage and homeostasis of iron. Its importance for microbial growth makes its uptake systems a natural target for pathogenic microorganisms and parasites. Uniquely, humans suffer from both iron deficiency and iron overload, while the capacity of iron to generate highly reactive free radicals, causing oxidative stress, is associated with a wide range of human pathologies, including many neurodegenerative diseases. Whereas some essential metal ions like copper and zinc are closely linked with iron metabolism, toxic metals like aluminium and cadmium can interfere with iron metabolism. Finally, iron metabolism and homeostasis are key targets for the development of new drugs for human health. The 4th edition of Iron Metabolism is written in a lively style by one of the leaders in the field, presented in colour and covers the latest discoveries in this exciting area. It will be essential reading for researchers and students in biochemistry, molecular biology, microbiology, cell biology, nutrition and medical sciences. Other interested groups include biological inorganic chemists with an interest in iron metabolism, health professionals with an interest in diseases of iron metabolism, or of diseases in which iron uptake systems are involved (eg. microbial and fungal infections, cancer, neurodegenerative disorders), and researchers in the pharmaceutical industry interested in developing novel drugs targeting iron metabolism/homeostasis.



Iron Transport And Storage


Iron Transport And Storage
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Author : Prem Ponka
language : en
Publisher: CRC Press
Release Date : 1990-09-25

Iron Transport And Storage written by Prem Ponka and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990-09-25 with Medical categories.


The objective of this book is to review and summarize recent developments in our understanding of iron transport and storage in living systems. It includes an overview of the evolutionary aspects of iron metabolism and bacterial iron transport, as well as a detailed discussion of molecules with specific roles in iron metabolism in higher organisms. It also presents relationships between intracellular iron metabolism and cell proliferation. Iron Transport and Storage addresses the comparative aspects of iron transport and storage in different tissues. This essential volume is very useful for hematologists, physical and biological chemists, cell and molecular biologists, physiologists, and clinicians with an interest in the biology and metabolism of iron.



Iron Metabolism


Iron Metabolism
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Author : Robert Crichton
language : en
Publisher: Wiley
Release Date : 2009-05-26

Iron Metabolism written by Robert Crichton and has been published by Wiley this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-05-26 with Medical categories.


Iron is of fundamental importance to the growth, development and well-being of almost all living organisms. Multiple biological systems have evolved for the uptake, utilisation, storage, and homeostasis of iron in microbes, plants and mammals. Both iron deficiency and iron overload are found extensively in humans; the intimate links between iron and oxidative stress are associated with a wide range of pathologies. Iron has a well established role in infections by a range of microorganisms and parasites. Other metals such as copper and zinc are also closely linked with iron metabolism. Iron overloads and deficiencies are important factors in the health of humans and are therefore a key target in drug development. Iron Metabolism: From Molecular Mechanisms to Clinical Consequences, 3rd Edition presents a comprehensive overview of this important field.Topics covered include: Solution chemistry of iron in biological media The importance of iron for biological systems Microbial iron transport and metabolism Iron uptake by plants and fungi Cellular iron uptake and export in mammals Intracellular iron storage and biomineralization Intracellular iron metabolism and cellular iron homeostasis Iron absorption in mammals, with particular reference to man, and regulation of systemic iron balance Pathophysiology of iron deficiency and iron overload in man Iron and oxidative stress Brain iron homeostasis and its perturbation in various neurodegenerative diseases Interactions between iron and other metals Written in a lively style by one of the leaders in the field and presented in full colour, this third, expanded edition of Iron Metabolism has been fully updated with the latest discoveries. Major additions include recent information on mitochondrial iron metabolism and the role of frataxin; transcriptional control of iron homeostasis; orally active iron chelators; the roles of hepcidin and erythropoietin; the increasing number of types of iron overload; and the importance of iron in Alzheimer’s disease. Iron Metabolism is essential reading for researchers and students in biochemistry, molecular biology, microbiology, cell biology, nutrition and the medical sciences. It will also find space on the bookshelves of bioinorganic chemists with an interest in iron metabolism, health professionals with an interest in diseases of iron metabolism, and pharmacologists in the pharmaceutical industry interested in developing novel iron-binding drugs.



Iron Metabolism


Iron Metabolism
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Author : Ivan Bernat
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Iron Metabolism written by Ivan Bernat and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.




The Biological Chemistry Of Iron


The Biological Chemistry Of Iron
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Author : B.H. Dunford
language : en
Publisher: Springer
Release Date : 1982-07-31

The Biological Chemistry Of Iron written by B.H. Dunford and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982-07-31 with Science categories.


The results of a NATO Advanced Study Institute (ASI) entitled "Coordination Chemistry Environments in Iron-Containing Proteins and Enzymes - Including Smaller Molecules and Model Systems" are summarized in this book. The ASI was held in the Province of Alberta, Canada, from August 23 to September 4, 1981. The first half of the conference was held on the campus of the University of Alberta, Edmonton, and the second half at the Overlander Lodge, Hinton. Two other conferences had the greatest impact upon the planning for this ASI. One was a NATO ASI held in Tomar, Portugal in September of 1979, entitled "Metal Ions in Biology". Among the organizers for that conference were Allen Hill and Antonio Xavier; we are happy to acknowledge their beneficial influence on our subsequent conference. The other most influential conference was one organized by Ralph Wilkins and Dennis Darnell entitled "Methods for Determining Metal Ion Environments in Proteins" which was held in Las Cruces, New Mexico, U.S.A., January 10-12, 1979. The Las Cruces conference invited lectures were published as Volume 2 of "Advances in Inorganic Biochemistry", G. Eichhorn and L. Marzilli, editors.