Long Non Coding Rnas Function Mechanisms And Applications
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Long Non Coding Rnas In Cancer
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Author : Alfons Navarro
language : en
Publisher: Humana
Release Date : 2021-06-24
Long Non Coding Rnas In Cancer written by Alfons Navarro and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-24 with Medical categories.
This volume presents techniques needed for the study of long non-coding RNAs (lncRNAs) in cancer from their identification to functional characterization. Chapters guide readers through identification of lncRNA expression signatures in cancer tissue or liquid biopsies by RNAseq, single Cell RNAseq, Phospho RNAseq or Nanopore Sequencing techniques; validation of lncRNA signatures by Real time PCR, digital PCR or in situ hybridization; and functional analysis by siRNA or CRISPR based methods for lncRNA silencing or overexpression. Lipid based nanoparticles for delivery of siRNAs in vivo, lncRNA-protein interactions, viral lncRNAs and circRNAs are also treated in this volume. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and practical, Long Non-Coding RNAs in Cancer aims to provide a collection of laboratory protocols, bioinformatic pipelines, and review chapters to further research in this vital field.
Long Non Coding Rnas Function Mechanisms And Applications
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Author :
language : en
Publisher: BoD – Books on Demand
Release Date : 2025-07-02
Long Non Coding Rnas Function Mechanisms And Applications written by and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-07-02 with Science categories.
LncRNAs contribute to cancer progression by regulating gene expression epigenetically and post-transcriptionally. They influence tumorigenesis through interactions with chromatin modifiers, act as competitive endogenous RNAs to modulate microRNA activity and regulate processes such as epithelial-mesenchymal transition (EMT) that facilitate metastasis. LncRNAs affect cancer cell proliferation, apoptosis, migration, metabolism, and drug resistance, making them crucial players in tumor development and potential targets for diagnosis and therapy. The book covers the latest reports about lncRNAs.
Long Noncoding Rnas In Plants
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Author : Santosh Kumar Upadhyay
language : en
Publisher: Academic Press
Release Date : 2020-11-13
Long Noncoding Rnas In Plants written by Santosh Kumar Upadhyay and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-13 with Science categories.
The growth of human population has increased the demand for improved yield and quality of crops and horticultural plants. However, plant productivity continues to be threatened by stresses such as heat, cold, drought, heavy metals, UV radiations, bacterial and fungal pathogens, and insect pests. Long noncoding RNAs are associated with various developmental pathways, regulatory systems, abiotic and biotic stress responses and signaling, and can provide an alternative strategy for stress management in plants. Long Noncoding RNAs in Plants: Roles in development and stress provides the most recent advances in LncRNAs, including identification, characterization, and their potential applications and uses. Introductory chapters include the basic features and brief history of development of lncRNAs studies in plants. The book then provides the knowledge about the lncRNAs in various important agricultural and horticultural crops such as cereals, legumes, fruits, vegetables, and fiber crop cotton, and their roles and applications in abiotic and biotic stress management. - Includes the latest advances and research in long noncoding RNAs in plants - Provides alternative strategies for abiotic and biotic stress management in horticultural plants and agricultural crops - Focuses on the application and uses of long noncoding RNAs
Innovative Medicine
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Author : Kazuwa Nakao
language : en
Publisher: Springer
Release Date : 2015-10-13
Innovative Medicine written by Kazuwa Nakao and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-13 with Science categories.
This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.
Molecular Biology Of The Cell
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Author :
language : en
Publisher:
Release Date : 2004
Molecular Biology Of The Cell written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Cells categories.
Non Coding Rnas In Gastrointestinal And Gynecological Cancers New Insights Into The Mechanisms Of Cancer Therapeutic Resistance
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Author : Peixin Dong
language : en
Publisher: Frontiers Media SA
Release Date : 2022-07-13
Non Coding Rnas In Gastrointestinal And Gynecological Cancers New Insights Into The Mechanisms Of Cancer Therapeutic Resistance written by Peixin Dong and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-13 with Science categories.
Recent Progresses Of Non Coding Rnas In Biological And Medical Research 2nd Edition
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Author : Yun Zheng
language : en
Publisher: Frontiers Media SA
Release Date : 2020-11-04
Recent Progresses Of Non Coding Rnas In Biological And Medical Research 2nd Edition written by Yun Zheng and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-04 with Science categories.
Publisher’s note: In this 2nd edition, the following article has been updated: Xun Y, Tang Y, Hu L, Xiao H, Long S, Gong M, Wei C, Wei K and Xiang S (2019) Purification and Identification of miRNA Target Sites in Genome Using DNA Affinity Precipitation. Front. Genet. 10:778. doi: 10.3389/fgene.2019.00778
Targeted Drug Discovery In Ectopic Calcification Mechanism Prospect And Clinical Application
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Author : Kang Xu
language : en
Publisher: Frontiers Media SA
Release Date : 2023-05-26
Targeted Drug Discovery In Ectopic Calcification Mechanism Prospect And Clinical Application written by Kang Xu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-26 with Science categories.
Non Coding Rna In Plants
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Author : Rahul Datta
language : en
Publisher: Elsevier
Release Date : 2024-11-29
Non Coding Rna In Plants written by Rahul Datta and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-11-29 with Science categories.
Non-coding RNA in Plants: Modulation and Stress Responses is the first book to present the basics of the importance of long non-coding RNA and its potential in addressing abiotic and biotic stresses. Describing the MiRNA and small RNA and their role in plant development, this book explains the importance of long non-coding RNA in plants, including its significance in virus resistance, its transposable elements, effector trigger immunity, and fungal and bacterial resistance in plants. Non-coding RNA for Modulation and Stress Response in Plants presents the state-of-the-science from its historical foundation through application throughout the lifecycle and production of agricultural and non-agricultural plants. While various coding has been explored within animal science, plant exposition has been minimal. This book is designed to inspire additional research and developments toward improved plant resiliency and production. - Presents foundational information for understanding the importance of long non-coding RNA in plants - Summarizes and illustrates identification and diversity analysis approaches toward Non-coding RNA as regulations - Explores how non-coding RNAs may play a role in the regulation of stress responses by highlighting their biogenesis and mechanisms of action
Navigating Non Coding Rna
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Author : Joanna Sztuba-Solinska
language : en
Publisher: Elsevier
Release Date : 2023-06-17
Navigating Non Coding Rna written by Joanna Sztuba-Solinska and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-17 with Science categories.
Navigating Non-coding RNA: From Biogenesis to Therapeutic Application provides a concise overview of the field of non-coding RNA (ncRNA). Chapters cover the history of discoveries that have occurred in the area of ncRNA, specific types of ncRNA, housekeeping ncRNAs such as ribosomal RNA, transfer RNA, small nuclear RNA and telomerase RNA, regulatory ncRNAs such as microRNA, small interfering RNA, long non-coding RNA and Y RNA. Biogenesis, structure, function, and regulation of each of these are also explored in addition to traditional and cutting-edge methods for the identification, functional characterization and structural characterization of ncRNA. The book also focuses on the different types of epitranscriptomic modifications and their involvement in regulating ncRNA structure, stability and intermolecular interactions in addition to the role of ncRNAs in a range of diseases and potential therapeutic applications. - Covers a wide range of non-coding RNAs, including ribosomal RNA, transfer RNA, telomerase RNA, microRNA, small interfering RNA and circular RNA - Features both traditional and novel methodologies for investigating ncRNA, from microarray and conventional chemical probing to CAGE-seq and computational methods - Includes chapters on ncRNAs in a range of diseases, including cancers, neurological disorders, cardiovascular conditions and infectious illnesses - Discusses novel therapeutic strategies for targeting ncRNAs, including CRISP/Ca9 applications and RNAi-based strategies - Explores the molecular mechanisms and intermolecular interactions of ncRNA