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Mechanobiology Of Fracture Healing

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Mechanobiology Of Fracture Healing

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Author : Lutz E. Claes
language : en
Publisher:
Release Date : 2022

Mechanobiology Of Fracture Healing written by Lutz E. Claes and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022 with categories.

This book offers a summary of research on the biomechanics of fracture fixation and mechanobiology of fracture healing. The author, a known expert, provides an overview of the state of art, his own research together with that of his co-workers and collaborators; he describes the ideas and findings from the beginning of this research field in the 1960s up to the clinical consequences and applications of today. The book discusses the mechanobiology of fracture healing, illustrates the numerical methods that simulate fracture healing processes, and depicts specific research methods of experimental studies. Finally, it provides conclusions for the improvement of fracture treatment that will be of use in clinical applications nowadays. This book will be a valuable resource of knowledge for students and scientists in the field of bioengineering, experimental biology, and biomechanics, helping them to identify the correct conditions and analysis for their respective research and receive an understanding of the research field from its beginning until today. For experimental and clinical surgeons active in the field of fracture healing, this book will provide a useful historical overview over this translational research field.

Mechanobiology Of Fracture Healing

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Author : Lutz E. Claes
language : en
Publisher: Springer
Release Date : 2022-04-25

Mechanobiology Of Fracture Healing written by Lutz E. Claes and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-25 with Technology & Engineering categories.

Multiscale Mechanobiology Of Bone Remodeling And Adaptation

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Author : Peter Pivonka
language : en
Publisher: Springer
Release Date : 2017-06-20

Multiscale Mechanobiology Of Bone Remodeling And Adaptation written by Peter Pivonka and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-20 with Science categories.

The book presents state-of-the-art developments in multiscale modeling and latest experimental data on multiscale mechanobiology of bone remodeling and adaptation including fracture healing applications. The multiscale models include musculoskeletal models describing bone-muscle interactions during daily activities such as walking or running, micromechanical models for estimation of bone mechanical properties, bone remodeling and adaptation models, cellular models describing the complex bone-cell interactions taking into account biochemical and biomechanical regulatory factors. Also subcellular processes are covered including arrangement of actin filaments due to mechanical loading and change of receptor configurations.

The Mechanobiology Of Diaphyseal Secondary Bone Healing

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Author : Devakara Rao Epari
language : en
Publisher:
Release Date : 2006

The Mechanobiology Of Diaphyseal Secondary Bone Healing written by Devakara Rao Epari and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with categories.

Basic Orthopaedic Biomechanics Mechano Biology

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Author : Van C. Mow
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 2005

Basic Orthopaedic Biomechanics Mechano Biology written by Van C. Mow and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Medical categories.

Biomaterials / Ahmed El-Ghannam and Paul Ducheyne -- Biomechanics of the spine / Ian A. F. Stokes and James C. Iatridis -- Biomechanics of fracture fixation and fracture healing / Lutz E. Claes and Keita Ito -- Biomechanics and preclinical testing of artificial joints: the hip / Rik Huiskes and Jan Stolk -- Biomechanics of total knee replacement designs / Peter S. Walker.

Mechanobiology

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Author : Glen L. Niebur
language : en
Publisher: Elsevier
Release Date : 2019-12-01

Mechanobiology written by Glen L. Niebur and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-01 with Science categories.

Mechanobiology: From Molecular Sensing to Disease will provide a review of the current state of understanding of mechanobiology and its role in health and disease. It covers: Current understanding of the main molecular pathways by which cells sense and respond to mechanical stimuli, A review of diseases that with known or purported mechanobiological underpinnings; The role of mechanobiology in tissue engineering and regenerative medicine; Experimental methods to capture mechanobiological phenomena; Computational models in mechanobiology. Presents our current understanding of the main molecular pathways by which cells sense and respond to mechanical stimuli Provides a review of diseases with known or purported mechanobiological underpinnings Includes the role of mechanobiology in tissue engineering and regenerative medicine Covers experimental methods to capture mechanobiological phenomena

Basic Orthopaedic Biomechanics And Mechano Biology

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Author : Van C. Mow
language : en
Publisher: Lww
Release Date : 2015-04-24

Basic Orthopaedic Biomechanics And Mechano Biology written by Van C. Mow and has been published by Lww this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-24 with categories.

Completely revised and updated, the Third Edition of this classic text reflects the latest advances in research on orthopaedic biomechanics and the successful applications of biomechanical principles in fracture fixation, prosthetic implant design, and hip and knee arthroplasty. For this Third Edition, Dr. Mow is joined by new co-editor Rik Huiskes, PhD, an Editor-in-Chief of the Journal of Biomechanics and an internationally renowned authority in the field. New chapters cover biomaterials, biomechanical principles of cartilage and bone tissue engineering, and biomechanics of fracture fixation and fracture healing.

Bone Cell Biomechanics Mechanobiology And Bone Diseases

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Author : Airong Qian
language : en
Publisher: Elsevier
Release Date : 2023-08-28

Bone Cell Biomechanics Mechanobiology And Bone Diseases written by Airong Qian and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-28 with Reference categories.

Bone Cell Biomechanics, Mechanobiology and Bone Diseases provides a comprehensive overview of recent knowledge and advances of bone cell biomechanics and related bone diseases, highlighting the cellular basis for bone responding to mechanical stimuli. The book not only provides a general overview of bone cell biology, but also the most recent advances of bone cell biomechanics, mechanobiology, the relationship between bone cell biomechanics and bone diseases, as well as the underlying mechanism. This will be useful in understanding the role of mechanobiology in bone health and bone diseases, as well for investigating novel strategies for diagnosis and therapy of bone diseases. Cells covered in the book include osteocyte, BM-MSC, osteoblast, osteoclast and chondrocyte. Cone diseases covered are osteoporosis, scoliosis and osteoarthritis. This comprehensive reference is written for researchers, scientists, clinicians and students. Presents a comprehensive introduction of current knowledge and recent advances of bone cell biomechanics Introduces new technologies for bone cell research Discusses the bone cell mechanotransduction, mechanism and bone diseases

The Pathomechanics Of Tissue Injury And Disease And The Mechanophysiology Of Healing

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Author : Amit Gefen
language : en
Publisher:
Release Date : 2009-01-01

The Pathomechanics Of Tissue Injury And Disease And The Mechanophysiology Of Healing written by Amit Gefen and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-01-01 with Bones categories.

Over the last decade, it became clear that mechanical factors, such as deformations, forces and stiffness properties have critical influence on a wide spectrum of diseases. Traditionally, since the 1960's, mechanics has been associated mainly with orthopaedics, trauma and rehabilitation as well as with cardiovascular problems, and so, the work of biomechanists was mostly related to these areas. This led, for example, to good understanding of the loading conditions at which bone fractures occur, and how bone fractures can be healed more quickly if their mechanical environment is adequately controlled (e.g. via compression plate-screw systems). However, more recently, on the 1980's-1990's, it was discovered that mechanics has much more fundamental roles and effects on biological processes, as many cell types appeared to be responsive to mechanical stimuli. This boosted biomechanical research on the effects of mechanical factors at the microscopic scale of tissues, and the fields of mechanobiology and mechanotransduction emerged. Most recently, on the 2000's, there were studies, e.g. by Dr. Valerie Weaver and colleagues (as described in this book), reporting that at the cell scale, inadequate mechanical stimuli may even provoke cancer. Hence, the role of integration between mechanics, life sciences and medicine is growing rapidly, and becomes more important by the day. What allows this integration to expand so fast is the development of sophisticated bioengineering research and analysis tools. These include highly realistic computer simulations, small animal MRI, micro-sensors, bio-reactors and many other recent breakthroughs that allow precision measurements of the mechanical conditions that apply in tissues at different levels of architectural hierarchy, whereas at the same time, close monitoring of the biological responses to these mechanical conditions became possible. This exciting atmosphere is at the background of the present book, which contains perspectives from leading scientists worldwide on the role of mechanics in injury, disease and healing. The topics covered span from bone tumors to pressure ulcers and from osteoarthritis to breast cancer, which illustrates how mechanics is now identified as the common denominator in so many important chronic conditions, as opposed to just trauma. In view of the multi-disciplinary and diverse nature of this book, I expect it to be appealing to a broad readership, obviously including biomechanists but also medical doctors, physiologists, cell biologists, physiotherapists, nurses and all those who are interested in reading on the latest developments in our journey towards understanding the complex connections between mechanics and biology.

Theoretical Biomechanics

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Author : Vaclav Klika
language : en
Publisher: BoD – Books on Demand
Release Date : 2011-11-25

Theoretical Biomechanics written by Vaclav Klika and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-11-25 with Medical categories.

During last couple of years there has been an increasing recognition that problems arising in biology or related to medicine really need a multidisciplinary approach. For this reason some special branches of both applied theoretical physics and mathematics have recently emerged such as biomechanics, mechanobiology, mathematical biology, biothermodynamics. This first section of the book, General notes on biomechanics and mechanobiology, comprises from theoretical contributions to Biomechanics often providing hypothesis or rationale for a given phenomenon that experiment or clinical study cannot provide. It deals with mechanical properties of living cells and tissues, mechanobiology of fracture healing or evolution of locomotor trends in extinct terrestrial giants. The second section, Biomechanical modelling, is devoted to the rapidly growing field of biomechanical models and modelling approaches to improve our understanding about processes in human body. The last section called Locomotion and joint biomechanics is a collection of works on description and analysis of human locomotion, joint stability and acting forces.

Mechanobiology Of Fracture Healing

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