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Myocardial Protection By Ischaemic Preconditioning


Myocardial Protection By Ischaemic Preconditioning
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Myocardial Protection By Ischaemic Preconditioning


Myocardial Protection By Ischaemic Preconditioning
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Author : David Michael Walker
language : en
Publisher:
Release Date : 1995

Myocardial Protection By Ischaemic Preconditioning written by David Michael Walker and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with categories.




Myocardial Preconditioning


Myocardial Preconditioning
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Author : Cherry L. Wainwright
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-22

Myocardial Preconditioning written by Cherry L. Wainwright and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-22 with Science categories.


This book is about the unique ability of the heart to protect itself against the serious consequences of an abrupt reduction in blood flow to the myocardium - a phenomenon which is switched on by stress and termed myocardial preconditioning. This volume describes the main features and characteristics of preconditioning, with respect to the time-course of the protective effect of the phenomenon (first and second windows) and the different sequelae of myocardial ischaemia against which it protects, such as myocardial injury, arrhythmias and contractile dysfunction. The proposed mechanisms underlying the fascinating form of cardioprotection are discussed. Among these are the role of endogenous labile mediators, receptor-linked G proteins, ATP-sensitive potassium channels and protein kinase C activation.



Ischaemic Preconditioning Of The Human Heart


Ischaemic Preconditioning Of The Human Heart
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Author : Sudip Ghosh
language : en
Publisher:
Release Date : 2003

Ischaemic Preconditioning Of The Human Heart written by Sudip Ghosh and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with categories.




Myocardial Protection


Myocardial Protection
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Author : Tomas A. Salerno
language : en
Publisher: John Wiley & Sons
Release Date : 2008-04-15

Myocardial Protection written by Tomas A. Salerno and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-15 with Medical categories.


Myocardial protection is regarded as one of the most important, yet also most controversial aspects of cardiac surgery. There has been considerable improvement in myocardial protection strategies over recent years, utilising a variety of new approaches to treat cardiac diseases, and this text is intended to embrace the state of the art in this field. The book summarises the state of knowledge on all aspects of myocardial protection, including the latest in the treatment of cardiac diseases, robotics, pediatric surgery and the treatment of cardiac failure. Robotic surgery, valvular surgery, pediatric surgery and coronary surgery are all covered by renowned experts, producing a comprehensive, forward-looking view of the field of myocardial protection. This book should function to update physicians and surgeons interested in the field of cardiac surgery on the current state of knowledge on myocardial protection.



Myocardial Ischemia And Preconditioning


Myocardial Ischemia And Preconditioning
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Author : Naranjan S. Dhalla
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Myocardial Ischemia And Preconditioning written by Naranjan S. Dhalla and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


Current evidence suggests that the ischemic preconditioning response is a multi-factorial process consisting of an initial early trigger, an intermediate mediator, and an end effector. Each of these steps in is now its own intense area of investigation. The need to render the heart ischemic for a brief period to invoke the preconditioning response is currently the major factor limiting clinical application of this powerful cardioprotective strategy. Recent research efforts have utilized brief exposures to pharmacological agents, in lieu of a brief preconditioning ischemia, to trigger/mimic the ischemic preconditioning-induced response. The World Heart Congress held in Winnipeg in July 2001 provided a forum for the presentation of new insights into the basic mechanisms of ischemia and reperfusion injury, as well as novel strategies to protect the heart from cell death, ventricular arrhythmias, and contractile dysfunction. Many pioneers in the fields of ischemia-reperfusion injury and preconditioning-induced protection presented there and the chapters in this book represent selected papers from these symposia.



Ischemic Preconditioning The Concept Of Endogenous Cardioprotection


Ischemic Preconditioning The Concept Of Endogenous Cardioprotection
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Author : Karin Przyklenk
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Ischemic Preconditioning The Concept Of Endogenous Cardioprotection written by Karin Przyklenk and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


Ischemic Preconditioning: The Concept of Endogenous Cardioprotection consolidates, in one volume, both current knowledge and the most recent advances in ischemic preconditioning. The editors have invited investigators at the forefront of ongoing research to provide their scholarly and candid comments concerning each of these issues. This volume includes a comprehensive review of infarct size reduction with ischemic preconditioning, and the most recent data on the effects of preconditioning on ischemia and reperfusion-induced arrhythmias, myocardial metabolism, contractile function, and the coronary vasculature. The role of altered energy metabolism, stress-induced proteins, ATP-sensitive potassium channels, and adenosine -- the major hypotheses that have been proposed to explain the cardioprotective effects of ischemic preconditioning -- are critically reviewed by investigators who have been instrumental in developing these concepts. In addition, the editors raise the intriguing possibility that ischemic preconditioning may be more than simply a laboratory curiosity. Using a multidisciplinary approach, this volume challenges the readers to contribute their own expertise to address the unanswered questions concerning this endogenous, cardioprotective phenomenon.



Ischaemic Preconditioning Of Human Atrium


Ischaemic Preconditioning Of Human Atrium
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Author :
language : en
Publisher:
Release Date : 1997

Ischaemic Preconditioning Of Human Atrium written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with categories.




Myocardial Preservation Preconditioning And Adaptation


Myocardial Preservation Preconditioning And Adaptation
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Author : Dipak Kumar Das
language : en
Publisher:
Release Date : 1996

Myocardial Preservation Preconditioning And Adaptation written by Dipak Kumar Das and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Medical categories.


In this volume, basic scientists, cardiologists and cardiac surgeons discuss all that is known about preconditioning/adaptation and how this state-of-the-art technique compares with conventional techniques of myocardial preservation, unveiling its mechanism of protection and potential clinical application.



Ischaemia


Ischaemia
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Author : M. Marber
language : en
Publisher: BIOS Scientific Publishers
Release Date : 1996-07-01

Ischaemia written by M. Marber and has been published by BIOS Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-07-01 with Science categories.


Most research on myocardial protection is now focused on ischaemic preconditioning. This book is a unique collection of articles by researchers at the cutting edge of preconditioning research. Using a multidisciplinary approach, it presents information on the mechanisms of preconditioning and examines how these mechanisms are relevant to the human heart.



Myocardial Ischemia Mechanisms Reperfusion Protection


Myocardial Ischemia Mechanisms Reperfusion Protection
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Author : Morris Karmazyn
language : en
Publisher: Birkhäuser
Release Date : 2013-03-12

Myocardial Ischemia Mechanisms Reperfusion Protection written by Morris Karmazyn and has been published by Birkhäuser this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-12 with Medical categories.


Myocardial ischemia and subsequent reperfusion of the ischemic myocardium represent complex phenomena encompassing numerous physiological processes. This book aims at enhancing our understanding of these processes and stresses recent important developments in this very active area of research. The concise, state-of-the-art reviews cover recent advances in many fields important to the area of myocardial ischemia and reperfusion including physiology, pathology, pharmacology, biochemistry and molecular biology with reference to clinical relevance and applicability of these findings. Major areas which are highlighted include vascular mechanisms resulting in myocardial ischemia, cellular events in the ischemic, postinfarcted and reperfused myocardium as well as new exciting developments in cardiac protection that involve both novel pharmacological approaches as well as endogenous cardioprotective mechanisms such as preconditioning. Aimed at both the basic and clinical cardiovascular investigator, the book comprehensively reviews the rapid progress made in recent years in understanding the etiology of myocardial ischemia and reperfusion. It will further serve as an authoritative reference for all those interested in learning about the important developments in the treatment of myocardial ischemic and reperfusion disorders.