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Polymer Translocation Through Conical Pores


Polymer Translocation Through Conical Pores
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Polymer Translocation Through Conical Pores


Polymer Translocation Through Conical Pores
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Author : Andri Sharma
language : en
Publisher:
Release Date : 2024-02-04

Polymer Translocation Through Conical Pores written by Andri Sharma and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-02-04 with Computers categories.


The fundamental unit of heredity is DNA (Deoxyribonucleic acid), which carries the ge- netic information of living species. DNA is a complex molecule where each molecule consists of two strands twisted to form a double helical structure[11]. The backbone of strands is made up of alternative sugar and phosphate groups, and these strands are bonded together with base pairs formed from four bases: Adenine(A) with Thymine(T), and Cytosine(C) with Guanine(G). The bases are organized in a sequence one after an- other to form a genetic code. Decoding the code extracts the information contained inside the DNA! With this knowledge in mind Human Genome Project (HGP) [12] was initiated in 1990 with a cost of 2.7 billion dollars to read the human genome, which has approx 3 billion base pairs. The project was closed in 2003, reporting a 1.3 billion base-pairs count of DNA in the human genome. A lot of engineering techniques and technologies have been developed over the years to extract information about the organism. Generation after generation, various techniques have been introduced to reduce the time and cost of DNA sequencing.



Polymer Translocation


Polymer Translocation
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Author : M Muthukumar
language : en
Publisher: CRC Press
Release Date : 2019-08-30

Polymer Translocation written by M Muthukumar and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-30 with categories.


Polymer translocation occurs in many biological and biotechnological phenomena where electrically charged polymer molecules move through narrow spaces in crowded environments. Unraveling the rich phenomenology of polymer translocation requires a grasp of modern concepts of polymer physics and polyelectrolyte behavior. Polymer Translocation discusses universal features of polymer translocations and summarizes the key concepts of polyelectrolyte structures, electrolyte solutions, ionic flow, mobility of charged macromolecules, polymer capture by pores, and threading of macromolecules through pores. With approximately 150 illustrations and 850 equations, the book: Avoids heavy mathematics Uses examples to illustrate the richness of the phenomenon Introduces the entropic barrier idea behind polymer translocation Outlines conceptual components necessary for a molecular understanding of polymer translocation Provides mathematical formulas for the various quantities pertinent to polymer translocation The challenge in understanding the complex behavior of translocation of polyelectrolyte molecules arises from three long-range forces due to chain connectivity, electrostatic interactions, and hydrodynamic interactions. Polymer Translocation provides an overview of fundamentals, established experimental facts, and important concepts necessary to understand polymer translocation. Readers will gain detailed strategies for applying these concepts and formulas to the design of new experiments.



Advances In Immunoassay Technology


Advances In Immunoassay Technology
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Author : Norman Chiu
language : en
Publisher: BoD – Books on Demand
Release Date : 2012-03-23

Advances In Immunoassay Technology written by Norman Chiu and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-03-23 with Medical categories.


From the basic in vitro study of a specific biomolecule to the diagnosis or prognosis of a specific disease, one of the most widely used technology is immunoassays. By using a specific antibody to recognize the biomolecule of interest, relatively high specificity can be achieved by immunoassays, such that complex biofluids (e.g. serum, urine, etc.) can be analyzed directly. In addition to the binding specificity, the other key features of immunoassays include relatively high sensitivity for the detection of antibody-antigen complexes, and a wide dynamic range for quantitation. Over the past decade, the development and applications of immunoassays have continued to grow exponentially. This book focuses on some of the latest technologies for the development of new immunoassays.



Nanoscience


Nanoscience
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Author : Patrick Boisseau
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-10-14

Nanoscience written by Patrick Boisseau and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-10-14 with Technology & Engineering categories.


Nanobiotechnology is a rapidly developing field of research with new applications constantly emerging. This book presents the basics, fundamental results and latest achievements of nanobiotechnological research. It extends as far as promising applications of new nanomaterials and newly discovered nanoeffects. Additionally, it presents a large variety of nanobio-analysis methods.



Handbook Of Single Molecule Biophysics


Handbook Of Single Molecule Biophysics
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Author : Peter Hinterdorfer
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-12-24

Handbook Of Single Molecule Biophysics written by Peter Hinterdorfer and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12-24 with Science categories.


This handbook describes experimental techniques to monitor and manipulate individual biomolecules, including fluorescence detection, atomic force microscopy, and optical and magnetic trapping. It includes single-molecule studies of physical properties of biomolecules such as folding, polymer physics of protein and DNA, enzymology and biochemistry, single molecules in the membrane, and single-molecule techniques in living cells.



Solid State Nanopores


Solid State Nanopores
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Author : Jean-Pierre Leburton
language : en
Publisher: Springer Nature
Release Date : 2023-09-30

Solid State Nanopores written by Jean-Pierre Leburton and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-30 with Technology & Engineering categories.


This contributed volume provides an overview of the recent advances in solid-state nanopore technology, featuring contributions by leading experts in the field. It discusses several aspects of solid-state nanopores, covering their fabrication as well as multiple biosensing applications. It successfully bridges the gap between various scientific and engineering disciplines and highlights the progress made in this area. This title is a useful tool for acquiring basic knowledge of this field and following recent progress. It is a valuable contribution to the area of nanopore biosensing and is of interest to graduate students, postdocs, or senior researchers working in the fields of physical chemistry, biochemistry, bio- and electrical engineering, and biophysics.



Functional Nanostructured Membranes


Functional Nanostructured Membranes
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Author : Enrico Drioli
language : en
Publisher: CRC Press
Release Date : 2018-12-07

Functional Nanostructured Membranes written by Enrico Drioli and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-12-07 with Science categories.


A membrane is considered the heart of every separation process because it is developed as a nanostructured/nanofunctionalized thin barrier that controls the exchange between two phases, not only by external forces and under the effect of fluid properties, but also through the intrinsic characteristics of the membrane material itself. This book compiles cutting-edge research in membrane science, nanomaterials, and nanotechnologies, mainly from interdisciplinary research groups at the Institute on Membrane Technology, National Research Council (ITM-CNR), Italy, working on membrane design, membrane process engineering, and selected materials and practices for enhanced transport mass, charge, and energy. It covers topics on the design of new nanostructured membranes with improved properties, together with the identification of efficient transport–property relationships. It shares and strengthens the knowledge of making membrane technology a much more powerful and eco-friendly route, enabling one to provide prospective solutions and benefits for numerous fields of applications where traditional separation technologies suffer from many deficiencies. It is a great reference for researchers and investigators; graduate, PhD, and postgraduate students; and end users interested in membrane science and technology, nanomaterials, eco-friendly separation, chemistry, biology, and process engineering.



Nanopores


Nanopores
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Author : Samir M. Iqbal
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-07-12

Nanopores written by Samir M. Iqbal and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-07-12 with Technology & Engineering categories.


Nanopores are nanometer scale holes formed naturally by proteins or cells, and can be used for a variety of applications, including sequencing DNA and detecting anthrax. They can be integrated into artificially constructed encapsulated cells of silicon wafers while allowing small molecules like oxygen, glucose and insulin to pass, while keeping out large system molecules. "Nanopores: Sensing and Fundamental Biological Interactions" examines the emerging research directions surrounding nanopores such as genome sequencing and early disease detection using biomarker identification. Covering the applications of nanopores in genetics, proteomics, drug discovery, early disease detection and detection of emerging environmental threats, it is a must-have book for biomedicalengineers and research scientists.



Bio Inspired Asymmetric Design And Building Of Biomimetic Smart Single Nanochannels


Bio Inspired Asymmetric Design And Building Of Biomimetic Smart Single Nanochannels
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Author : Xu Hou
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-05-28

Bio Inspired Asymmetric Design And Building Of Biomimetic Smart Single Nanochannels written by Xu Hou and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-28 with Technology & Engineering categories.


In this thesis, the author introduces various bio-inspired smart nanochannel systems. A strategy for design and preparation of novel artificial responsive symmetric/asymmetric single nanochannel systems under various symmetric/asymmetric stimuli is presented for the first time. The author’s research work utilizes ion track etching polymer nanochannels with different shapes as examples to demonstrate the feasibility of the design strategy for building novel artificial functional nanochannels using various symmetric/asymmetric physicochemical modifications. The development of these nanochannels and their potential applications is a burgeoning new area of research, and a number of exciting breakthroughs may be anticipated in the near future from the concepts and results reported in this thesis. Research into artificial functional nanochannels continues to drive new developments of various real-world applications, such as biosensors, energy conversion systems and nanofluidic devices. The work in this thesis has led to more than 15 publications in high-profile journals.



Molecular And Nano Tubes


Molecular And Nano Tubes
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Author : Oliver Hayden
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-08-04

Molecular And Nano Tubes written by Oliver Hayden and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-04 with Technology & Engineering categories.


Molecular- and Nano-Tubes summarizes recent advancements in the synthesis, fabrication and applications of tubular structures. An interdisciplinary overview of innovative science focused on tubular structures is provided. The reader is offered an overview of the different fields that molecular and nano tubes appear in, in order to learn the fundamental basics as well as the applications of these materials. This book also: Shows how nanotechnology creates novel materials by crossing the barriers between biology and material science, electronics and optics, medicine and more Demonstrates that tubes are a fundamental element in nature and used in disparate applications such as ion channels and carbon nanotubes Molecular- and Nano-Tubes is an ideal volume for researchers and engineers working in materials science and nanotechnology.