Preparative And Process Scale Liquid Chromatography
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Process Scale Liquid Chromatography
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Author : Ganapathy Subramanian
language : en
Publisher: John Wiley & Sons
Release Date : 2008-07-11
Process Scale Liquid Chromatography written by Ganapathy Subramanian and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-07-11 with Science categories.
This book provides the industrial chromatographer and production scientist with a comprehensive account of process scale liquid chromatography. The basic theory is presented, guiding the reader through system design, simulation and modelling techniques, giving due consideration to economic aspects, as well as safety and regulatory factors. A thorough, up-to-date survey of current techniques and media does stress their advantages and limitations in such a way as to faciliate their application to real-life problems. In view of rapid rate of development in industrial chromatography one chapter provides an assessment of future developments. The chapters are written by acknowledged experts from Europe and the United States.
Preparative And Process Scale Liquid Chromatography
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Author : G. Subramanian
language : en
Publisher: Ellis Horwood
Release Date : 1991
Preparative And Process Scale Liquid Chromatography written by G. Subramanian and has been published by Ellis Horwood this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Science categories.
Emphasizing the practical applications and limitations of each technique, this text on separations in liquid chromatography describes the cost-effectiveness of each operation and its theory. It also provides information on media design, column technology and packing materials.
Scale Up And Optimization In Preparative Chromatography
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Author : Anurag Rathore
language : en
Publisher: CRC Press
Release Date : 2002-09-26
Scale Up And Optimization In Preparative Chromatography written by Anurag Rathore and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-09-26 with Medical categories.
Presenting guidelines to predict and improve separation system performance, this book contains numerous case studies illustrating the practice of scale-up principles in process development. It offers solutions to limitations that occur in real-world purification schemes; methods to model, optimize, and characterize nonlinear separation processes; data comparisons from all stages of production; and industrial separation schemes for products such as synthetic molecules, antibody fragments, IgG, growth factors, and plasmid DNA. The book covers external constraints, separation economics, correlations for transport and kinetic phenomena, and the configuration and parameters of column design.
Process Scale Purification Of Antibodies
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Author : Uwe Gottschalk
language : en
Publisher: John Wiley & Sons
Release Date : 2017-03-02
Process Scale Purification Of Antibodies written by Uwe Gottschalk and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-02 with Medical categories.
Promoting a continued and much-needed renaissance in biopharmaceutical manufacturing, this book covers the different strategies and assembles top-tier technology experts to address the challenges of antibody purification. • Updates existing topics and adds new ones that include purification of antibodies produced in novel production systems, novel separation technologies, novel antibody formats and alternative scaffolds, and strategies for ton-scale manufacturing • Presents new and updated discussions of different purification technologies, focusing on how they can address the capacity crunch in antibody purification • Emphasizes antibodies and innovative chromatography methods for processing
Preparative Enantioselective Chromatography
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Author : Geoffrey B. Cox
language : en
Publisher: John Wiley & Sons
Release Date : 2008-04-15
Preparative Enantioselective Chromatography written by Geoffrey B. Cox and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-15 with Science categories.
The development of chiral liquid chromatography, facilitating thestraightforward separation of enantiomers, was a significantadvance in chromatography, leading to widespread application inanalytical chemistry. Application in preparative chromatography hasbeen less rapid, but with the development of single enantiomerpharmaceuticals its use is increasingly common in chemicalsynthesis at laboratory, pilot plant and even full productionscale. Brings non-experts up to speed quickly and comprehensively,facilitating the rapid development of effective separations ofenantiomeric mixtures on a range of process scales Presents case studies drawn from within the pharmaceuticalindustry to clearly illustrate the utility and value of preparativescale enantioselective chromatography in chemical research,development and production Key reference source and entry to the literature so the readerdoes not have to engage in expensive and time consuming literaturesearching
Handbook Of Methods And Instrumentation In Separation Science
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Author :
language : en
Publisher: Academic Press
Release Date : 2009-11-11
Handbook Of Methods And Instrumentation In Separation Science written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-11 with Science categories.
Handbook of Methods and Instrumentation in Separation Science, Volume 1 provides concise overviews and summaries of the main methods used for separation. It is based on the Encyclopedia of Separation Science. The handbook focuses on the principles of methods and instrumentation. It provides general concepts concerning the subject matter; it does not present specific procedures. This volume discusses the separation processes including affinity methods, analytical ultracentrifugation, centrifugation, chromatography, and use of decanter centrifuge and dye. Each methodology is defined and compared with other separation processes. It also provides specific techniques, principles, and theories concerning each process. Furthermore, the handbook presents the applications, benefits, and validation of the processes described in this book. This handbook is an excellent reference for biomedical researchers, environmental and production chemists, flavor and fragrance technologists, food and beverage technologists, academic and industrial librarians, and nuclear researchers. Students and novices will also find this handbook useful for practice and learning. - One-stop source for information on separation methods - General overviews for quick orientation - Ease of use for finding results fast - Expert coverage of major separation methods - Coverage of techniques for all sizes of samples, pico-level to kilo-level
Preparative Chromatography Techniques
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Author : Kurt Hostettmann
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-17
Preparative Chromatography Techniques written by Kurt Hostettmann and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-17 with Science categories.
Over the last few years several new instrumental techniques have been introduced for chromatographie separations. In addition, rapid developments in existing methods, such as preparative HPLC, have taken place. Despite these advances, how ever, a handbook covering the various preparative aspects ofthe new separation tech niques does not exist. This book is an attempt to fill the gap and to present a compila tion of modern separation techniques that will be useful for researchers faced with day-to-day preparative problems. Numerous examples of separations have been selected in order to show the possibilities (and also the limits) of each technique treated. These are often either applications from our own laboratory or else they reflect the approach we have been following for the isolation of natural products from plant sourees. Owing to the large number of published papers and the diversity of secondary plant constituents. an exhaustive survey of the literature has not been undertaken. We hope, however, that the examples selected will suggest to the reader which technique(s) and which conditions to choose for a particular isolation problem in the field of natural products. For invaluable help in the preparation of the manuscript for this book, we would like to thank Corinne Appolonia and Christine Marston. Lausanne, November 1985 K. Hostettmann M. Hostettmann A . . Marston Foreword Although not many people realize this, isolation and purification of biologically active materials is becoming increasingly crucial.
Principles And Practice Of Modern Chromatographic Methods
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Author : Kevin Robards
language : en
Publisher: Academic Press
Release Date : 2021-12-03
Principles And Practice Of Modern Chromatographic Methods written by Kevin Robards and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-03 with Science categories.
Principles and Practice of Modern Chromatographic Methods, Second Edition takes a comprehensive, unified approach in its presentation of chromatographic techniques. Like the first edition, the book provides a scientifically rigid, but easy-to-follow presentation of chromatography concepts that begins with the purpose and intent of chromatographic theory - the "what and why that are left out of other books attempting to cover these principles. This fully revised second edition brings the content up-to-date, covering recent developments in several new sections and an additional chapter on composite methods. New topics include sample profiling, sample preparation, sustainable green chemistry, 2D chromatography, miniaturization/nano-LC, HILIC, and more. - Contains thorough chapters that begin with an updated schematic overview and a visual representation of the content - Avoids the obfuscation of different terminologies and classification systems that are prevalent in the area, such as the relationship between liquid chromatography and column chromatography - Provides integrated and comprehensive topic coverage based on chromatographic bibliometrics and survey reports on the relative usage of chromatographic techniques
Preparative Chromatography
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Author : H. Schmidt-Traub
language : en
Publisher: John Wiley & Sons
Release Date : 2020-02-27
Preparative Chromatography written by H. Schmidt-Traub and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-27 with Science categories.
The third edition of this popular work is revised to include the latest developments in this fast-changing field. Its interdisciplinary approach elegantly combines the chemistry and engineering to explore the fundamentals and optimization processes involved.
Fundamentals Of Preparative And Nonlinear Chromatography
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Author : Georges Guiochon
language : en
Publisher: Elsevier
Release Date : 2006-02-10
Fundamentals Of Preparative And Nonlinear Chromatography written by Georges Guiochon and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-02-10 with Science categories.
Fundamentals of Preparative and Nonlinear Chromatography, Second Edition is devoted to the fundamentals of a new process of purification or extraction of chemicals or proteins widely used in the pharmaceutical industry and in preparative chromatography. This process permits the preparation of extremely pure compounds satisfying the requests of the US Food and Drug Administration. The book describes the fundamentals of thermodynamics, mass transfer kinetics, and flow through porous media that are relevant to chromatography. It presents the models used in chromatography and their solutions, discusses the applications made, describes the different processes used, their numerous applications, and the methods of optimization of the experimental conditions of this process.