Preparative Chromatography
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Preparative Chromatography Techniques
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Author : Kurt Hostettmann
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-17
Preparative Chromatography Techniques written by Kurt Hostettmann and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-17 with Science categories.
Over the last few years several new instrumental techniques have been introduced for chromatographie separations. In addition, rapid developments in existing methods, such as preparative HPLC, have taken place. Despite these advances, how ever, a handbook covering the various preparative aspects ofthe new separation tech niques does not exist. This book is an attempt to fill the gap and to present a compila tion of modern separation techniques that will be useful for researchers faced with day-to-day preparative problems. Numerous examples of separations have been selected in order to show the possibilities (and also the limits) of each technique treated. These are often either applications from our own laboratory or else they reflect the approach we have been following for the isolation of natural products from plant sourees. Owing to the large number of published papers and the diversity of secondary plant constituents. an exhaustive survey of the literature has not been undertaken. We hope, however, that the examples selected will suggest to the reader which technique(s) and which conditions to choose for a particular isolation problem in the field of natural products. For invaluable help in the preparation of the manuscript for this book, we would like to thank Corinne Appolonia and Christine Marston. Lausanne, November 1985 K. Hostettmann M. Hostettmann A . . Marston Foreword Although not many people realize this, isolation and purification of biologically active materials is becoming increasingly crucial.
Preparative Chromatography
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Author : H. Schmidt-Traub
language : en
Publisher: John Wiley & Sons
Release Date : 2020-06-02
Preparative Chromatography written by H. Schmidt-Traub and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-02 with Science categories.
The third edition of this popular work is revised to include the latest developments in this fast-changing field. Its interdisciplinary approach elegantly combines the chemistry and engineering to explore the fundamentals and optimization processes involved.
Preparative Chromatography
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Author : H. Schmidt-Traub
language : en
Publisher: John Wiley & Sons
Release Date : 2006-03-06
Preparative Chromatography written by H. Schmidt-Traub and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-06 with Technology & Engineering categories.
This interdisciplinary approach combines the chemistry and engineering involved to describe the conception and improvement of chromatographic processes. The book covers recent developments in preparative chromatographic processes for the separation of "smaller" molecules using standard laboratory equipment as well as the detailed conception of industrial chemical plants. Following an introductory section on the history of chromatography, the current state of research and the design of chromatographic processes, the book goes on to define the general terminology. There then follow sections on solid materials and packed columns process concepts. Final chapters on modeling and determination of model parameters, the design and optimization of preparative chromatographic processes and chromatographic reactors allow for the optimum selection of chromatographic systems. Essential for chemists and engineers working in the chemicals and pharmaceutical industries as well as for food technologies, due to the interdisciplinary nature of these processes.
Scale Up And Optimization In Preparative Chromatography
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Author : Anurag Rathore
language : en
Publisher: CRC Press
Release Date : 2002-09-26
Scale Up And Optimization In Preparative Chromatography written by Anurag Rathore and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-09-26 with Medical categories.
Presenting guidelines to predict and improve separation system performance, this book contains numerous case studies illustrating the practice of scale-up principles in process development. It offers solutions to limitations that occur in real-world purification schemes; methods to model, optimize, and characterize nonlinear separation processes; d
Preparative Chromatography For Separation Of Proteins
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Author : Arne Staby
language : en
Publisher: John Wiley & Sons
Release Date : 2017-03-06
Preparative Chromatography For Separation Of Proteins written by Arne Staby and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-06 with Technology & Engineering categories.
Preparative Chromatography for Separation of Proteins addresses a wide range of modeling, techniques, strategies, and case studies of industrial separation of proteins and peptides. • Covers broad aspects of preparative chromatography with a unique combination of academic and industrial perspectives • Presents Combines modeling with compliantce useing of Quality-by-Design (QbD) approaches including modeling • Features a variety of chromatographic case studies not readily accessible to the general public • Represents an essential reference resource for academic, industrial, and pharmaceutical researchers
Fundamentals Of Preparative And Nonlinear Chromatography
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Author : Georges Guiochon
language : en
Publisher: Academic Press
Release Date : 2006-03-21
Fundamentals Of Preparative And Nonlinear Chromatography written by Georges Guiochon and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-21 with Medical categories.
The second edition of Fundamentals of Preparative and Nonlinear Chromatography is devoted to the fundamentals of a new process of purification or extraction of chemicals or proteins widely used in the pharmaceutical industry and in preparative chromatography. This process permits the preparation of extremely pure compounds satisfying the requests of the US Food and Drug Administration. The book describes the fundamentals of thermodynamics, mass transfer kinetics, and flow through porous media that are relevant to chromatography. It presents the models used in chromatography and their solutions, discusses the applications made, describes the different processes used, their numerous applications, and the methods of optimization of the experimental conditions of this process.
A Practical Handbook Of Preparative Hplc
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Author : Donald A. Wellings
language : en
Publisher: Elsevier Science Limited
Release Date : 2006
A Practical Handbook Of Preparative Hplc written by Donald A. Wellings and has been published by Elsevier Science Limited this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Medical categories.
This book is a distillation of twenty years of practical experience of the high pressure liquid chromatography (HPLC) process. Deliberately steering clear of complex theoretical aspects, this book concentrates on the everyday problems associated with the technique, making it perfect for frequent use in the laboratory and for those in the pharmaceutical, agrochemical and biotechnology industries for the analysis and purification of drugs, small molecules, proteins and DNA. This book… •Provides practical, hands-on advice based on years of experience •Will help ensure optimal design, equipment and separation results for your particular task •Presents system layouts from laboratory to process scale •Will help you to devise or improve record-keeping and documentation systems •Provides practical, hands-on advice based on years of experience •Will help ensure optimal design, equipment and separation results for your particular task •Presents system layouts from laboratory to process scale •Will help you to devise or improve record-keeping and documentation systems
Modeling For Preparative Chromatography
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Author : Georges Guiochon
language : en
Publisher: Academic Press
Release Date : 2003-05-19
Modeling For Preparative Chromatography written by Georges Guiochon and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-05-19 with Science categories.
Nonlinear chromatography is a field that borders both chemical engineering and physical chemistry. In turn, the theory of nonlinear chromatography is the foundation of preparative chromatography, a separation process that has lately become of considerable interest in the pharmaceutical industry. Only chromatography is sufficiently flexible and powerful to satisfy the practical requirements encountered in most difficult separations of pharmaceuticals and pharmaceutical intermediates. Since "nonlinear" behaviour is strictly a mathematical concept, it is difficult to leave mathematics out of any fundamental study of nonlinear chromatography. Therefore, Modeling for Preparative Chromatography will describe the different mathematical models of chromatography, examine the assumptions on which they are based, consider their properties, and discuss their solutions. All this will be done from a mathematical analysis point of view, paying considerable attention to the influence of nonlinear behavior on the results. Clear and simple discussions of the basic physico-chemical phenomena involved in HPLC Clear and complete presentation of the relevant properties of the mathematical tools involved Detailed analysis of nonlinear effects
Liquid Chromatography
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Author : M. Kaspereit
language : en
Publisher: Elsevier Inc. Chapters
Release Date : 2013-01-08
Liquid Chromatography written by M. Kaspereit and has been published by Elsevier Inc. Chapters this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-01-08 with Science categories.
This chapter describes rivalling operating modes applied industrially in preparative chromatography. After recapitulating the basic features of the “workhorse” and reference in the field, namely, isocratic batch elution, at first, more-sophisticated concepts are presented that offer additional degrees of freedom but maintain the discontinuous character of the separation process. Subsequently, process options are described that possess the potential to perform the separations continuously. Hereby, mainly the most successful multicolumn concepts are explained, which are based on realizing highly efficient countercurrent transport processes. Finally, the important aspect is addressedL how different process alternatives can be evaluated and compared quantitatively.
Preparative And Production Scale Chromatography
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Author : G. Ganetsos
language : en
Publisher: CRC Press
Release Date : 1992-09-16
Preparative And Production Scale Chromatography written by G. Ganetsos and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-09-16 with Science categories.
Describes the latest developments in the scaling-up and application of chromatographic operations and demonstrates that production-scale chromatography is a powerful and invaluable separation process. The book covers every important process design and reveals actual, immediately applicable techniques and is designed to appeal to design, chemical/biochemical, and research and development engineers, process development managers, bioprocess technologists, analytical and clinical chemists and biochemists, pharmacists, and upper-level undergraduate, graduate, and continuing-education students in these disciplines.