Proceedings Of The 6th Asia Pacific Bioinformatics Conference
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Proceedings Of The 6th Asia Pacific Bioinformatics Conference
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Author : Alvis Brazma
language : en
Publisher: World Scientific
Release Date : 2007-12-21
Proceedings Of The 6th Asia Pacific Bioinformatics Conference written by Alvis Brazma and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-12-21 with Science categories.
High-throughput sequencing and functional genomics technologies have given us the human genome sequence as well as those of other experimentally, medically, and agriculturally important species, thus enabling large-scale genotyping and gene expression profiling of human populations. Databases containing large numbers of sequences, polymorphisms, structures, metabolic pathways, and gene expression profiles of normal and diseased tissues are rapidly being generated for human and model organisms. Bioinformatics is therefore gaining importance in the annotation of genomic sequences; the understanding of the interplay among and between genes and proteins; the analysis of the genetic variability of species; the identification of pharmacological targets; and the inference of evolutionary origins, mechanisms, and relationships. This proceedings volume contains an up-to-date exchange of knowledge, ideas, and solutions to conceptual and practical issues of bioinformatics by researchers, professionals, and industry practitioners at the 6th Asia-Pacific Bioinformatics Conference held in Kyoto, Japan, in January 2008./a
Proceedings Of The 6th Asia Pacific Bioinformatics Conference
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Author : Alvis Brazma
language : en
Publisher: Imperial College Press
Release Date : 2008
Proceedings Of The 6th Asia Pacific Bioinformatics Conference written by Alvis Brazma and has been published by Imperial College Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Computers categories.
High-throughput sequencing and functional genomics technologies have given us the human genome sequence as well as those of other experimentally, medically, and agriculturally important species, thus enabling large-scale genotyping and gene expression profiling of human populations. Databases containing large numbers of sequences, polymorphisms, structures, metabolic pathways, and gene expression profiles of normal and diseased tissues are rapidly being generated for human and model organisms. Bioinformatics is therefore gaining importance in the annotation of genomic sequences; the understanding of the interplay among and between genes and proteins; the analysis of the genetic variability of species; the identification of pharmacological targets; and the inference of evolutionary origins, mechanisms, and relationships. This proceedings volume contains an up-to-date exchange of knowledge, ideas, and solutions to conceptual and practical issues of bioinformatics by researchers, professionals, and industry practitioners at the 6th Asia-Pacific Bioinformatics Conference held in Kyoto, Japan, in January 2008. Sample Chapter(s). Chapter 1: Recent Progress in Phylogenetic Combinatorics (185 KB). Contents: Recent Progress in Phylogenetic Combinatorics (A Dress); Predicting Nucleolar Proteins Using Support-Vector Machines (M Bod(r)n); Structure-Approximating Design of Stable Proteins in 2D HP Model Fortified by Cysteine Monomers (A H Khodabakhshi et al.); Seed Optimization Is No Easier than Optimal Golomb Ruler Design (B Ma & H Yao); Analysis of Structural Strand Asymmetry in Non-coding RNAs (J Wen et al.); Genome Halving with Double Cut and Join (R Warren & D Sankoff); Symbolic Approaches for Finding Control Strategies in Boolean Networks (C J Langmead & S K Jha); Optimal Algorithm for Finding DNA Motifs with Nucleotide Adjacent Dependency (F Y L Chin et al.); and other papers. Readership: Academics, researchers, and graduate students in bioinformatics and computer science.
Proceedings Of The 6th Asia Pacific Bioinformatics Conference
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Author : Alvis Brazma
language : en
Publisher:
Release Date : 2008
Proceedings Of The 6th Asia Pacific Bioinformatics Conference written by Alvis Brazma and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Computers categories.
Regulatory Genomics Proceedings Of The 3rd Annual Recomb Workshop
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Author : Hon Wai Leong
language : en
Publisher: World Scientific
Release Date : 2008-07-07
Regulatory Genomics Proceedings Of The 3rd Annual Recomb Workshop written by Hon Wai Leong and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-07-07 with Science categories.
Research in the field of gene regulation is evolving rapidly in the ever-changing scientific environment. Advances in microarray techniques and comparative genomics have enabled more comprehensive studies of regulatory genomics. The study of genomic binding locations of transcription factors has enabled a more comprehensive modeling of regulatory networks. In addition, complete genomic sequences and comparison of numerous related species have demonstrated the conservation of non-coding DNA sequences, which often provide evidence for cis-regulatory binding sites. Systematic methods to decipher the regulatory mechanism are also crucial for corroborating these regulatory networks; key to these methods are motif discovery algorithms that can help predict cis-regulatory elements. These DNA-motif discovery programs are becoming more sophisticated and are beginning to leverage evidence from comparative genomics. These topics and more were discussed at the 3rd Annual RECOMB Workshop on Regulatory Genomics, which brought together more than 90 attendees and included about 22 excellent talks from leading researchers in the field. This proceedings volume contains ten selected, original manuscripts that were presented during the workshop./a
Applications Of Fuzzy Logic In Bioinformatics
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Author : Dong Xu
language : en
Publisher: World Scientific
Release Date : 2008-08-11
Applications Of Fuzzy Logic In Bioinformatics written by Dong Xu and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-08-11 with Science categories.
Many biological systems and objects are intrinsically fuzzy as their properties and behaviors contain randomness or uncertainty. In addition, it has been shown that exact or optimal methods have significant limitation in many bioinformatics problems. Fuzzy set theory and fuzzy logic are ideal to describe some biological systems/objects and provide good tools for some bioinformatics problems. This book comprehensively addresses several important bioinformatics topics using fuzzy concepts and approaches, including measurement of ontological similarity, protein structure prediction/analysis, and microarray data analysis. It also reviews other bioinformatics applications using fuzzy techniques./a
Computational Methods For Understanding Bacterial And Archaeal Genomes
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Author : Ying Xu
language : en
Publisher: World Scientific
Release Date : 2008
Computational Methods For Understanding Bacterial And Archaeal Genomes written by Ying Xu and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Medical categories.
Over 500 prokaryotic genomes have been sequenced to date, and thousands more have been planned for the next few years. While these genomic sequence data provide unprecedented opportunities for biologists to study the world of prokaryotes, they also raise extremely challenging issues such as how to decode the rich information encoded in these genomes. This comprehensive volume includes a collection of cohesively written chapters on prokaryotic genomes, their organization and evolution, the information they encode, and the computational approaches needed to derive such information. A comparative view of bacterial and archaeal genomes, and how information is encoded differently in them, is also presented. Combining theoretical discussions and computational techniques, the book serves as a valuable introductory textbook for graduate-level microbial genomics and informatics courses.
Computational Systems Biology Of Synaptic Plasticity Modelling Of Biochemical Pathways Related To Memory Formation And Impairement
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Author : Don Kulasiri
language : en
Publisher: #N/A
Release Date : 2017-06-09
Computational Systems Biology Of Synaptic Plasticity Modelling Of Biochemical Pathways Related To Memory Formation And Impairement written by Don Kulasiri and has been published by #N/A this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-09 with Science categories.
This book demonstrates the power of mathematical thinking in understanding the biological complexity that exists within the brain. It looks at the latest research on modelling of biochemical pathways within synapses, and provides a clear background for the study of mathematical models related to systems biology. Discussion then focusses on developments in computational models based on networks linked to synaptic plasticity. The models are used to understand memory formation and impairment and they provide a mathematical basis for memory research.Computational Systems Biology of Synaptic Plasticity is a valuable source of knowledge to postgraduate students and researchers in computational systems biology, and as a reference book for various techniques that are needed in modelling biological processes.
Bioinformatics And Phylogenetics
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Author : Tandy Warnow
language : en
Publisher: Springer
Release Date : 2019-04-08
Bioinformatics And Phylogenetics written by Tandy Warnow and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-08 with Science categories.
This volume presents a compelling collection of state-of-the-art work in algorithmic computational biology, honoring the legacy of Professor Bernard M.E. Moret in this field. Reflecting the wide-ranging influences of Prof. Moret’s research, the coverage encompasses such areas as phylogenetic tree and network estimation, genome rearrangements, cancer phylogeny, species trees, divide-and-conquer strategies, and integer linear programming. Each self-contained chapter provides an introduction to a cutting-edge problem of particular computational and mathematical interest. Topics and features: addresses the challenges in developing accurate and efficient software for the NP-hard maximum likelihood phylogeny estimation problem; describes the inference of species trees, covering strategies to scale phylogeny estimation methods to large datasets, and the construction of taxonomic supertrees; discusses the inference of ultrametric distances from additive distance matrices, and the inference of ancestral genomes under genome rearrangement events; reviews different techniques for inferring evolutionary histories in cancer, from the use of chromosomal rearrangements to tumor phylogenetics approaches; examines problems in phylogenetic networks, including questions relating to discrete mathematics, and issues of statistical estimation; highlights how evolution can provide a framework within which to understand comparative and functional genomics; provides an introduction to Integer Linear Programming and its use in computational biology, including its use for solving the Traveling Salesman Problem. Offering an invaluable source of insights for computer scientists, applied mathematicians, and statisticians, this illuminating volume will also prove useful for graduate courses on computational biology and bioinformatics.
Essential Computing Skills For Biologists
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Author : Ziling Wang
language : en
Publisher: World Scientific
Release Date : 2018-07-02
Essential Computing Skills For Biologists written by Ziling Wang and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-02 with Science categories.
This is a handbook of methods and protocols for biologists. It aimed at undergraduate, graduate students and researchers originally trained in biological or medical sciences who need to know how to access the data archives of genomes, proteins, metabolites, gene expression profiles and the questions these data and tools can answer. For each chapter, the conceptual and experimental background is provided, together with specific guidelines for handling raw data, including preprocessing and analysis.The content is structured into three parts. Part one introduces basic knowledge about popular bioinformatics tools, databases and web resources. Part two presents examples of omics bioinformatics applications. Part three provides basic statistical analysis skills and programming skills needed to handle and analyze omics datasets.
Research In Computational Molecular Biology
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Author : Serafim Batzoglou
language : en
Publisher: Springer
Release Date : 2009-05-14
Research In Computational Molecular Biology written by Serafim Batzoglou and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-05-14 with Science categories.
This book constitutes the refereed proceedings of the 13th Annual International Conference on Research in Computational Molecular Biology, RECOMB 2009, held in Tucson, Arisona, USA in May 2009. The 37 revised full papers presented were carefully reviewed and selected from 166 submissions. As the top conference in computational molecular biology, RECOMB addresses all current issues in algorithmic, theoretical, and experimental bioinformatics such as molecular sequence analysis, recognition of genes and regulatory elements, molecular evolution, protein structure, structural genomics, gene expression, gene networks, drug design, combinatorial libraries, computational proteomics, as well as structural and functional genomics.