Revolutionizing Immunological Disease Understanding Through Single Cell Multi Omics Technologies
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Revolutionizing Immunological Disease Understanding Through Single Cell Multi Omics Technologies
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Author : Jennie R. Lill
language : en
Publisher: Frontiers Media SA
Release Date : 2025-06-17
Revolutionizing Immunological Disease Understanding Through Single Cell Multi Omics Technologies written by Jennie R. Lill and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-06-17 with Medical categories.
Single cell technologies, encompassing genomics and proteomics, are at the forefront of revolutionizing our understanding of biological mechanisms at the cellular level, particularly in the context of immunological diseases. These technologies have enabled researchers to dissect complex cellular processes with unprecedented detail, providing crucial spatial context that was previously unattainable. Recent advancements have led to the formulation of new signaling hypotheses and opened novel pathways for therapeutic interventions. The integration of multi-omics approaches, which combine various single cell technologies, has further enhanced our ability to explore intracellular signaling and disease pathology. Despite these advancements, challenges remain in optimizing data interpretation and understanding the full scope of these technologies' impact on immunological and cancer immunological disease pathogenesis. There is a pressing need for continued exploration and refinement of these methodologies to fully harness their potential in elucidating disease mechanisms.
Applications Of Multi Omics
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Author : Richard Skiba
language : en
Publisher: After Midnight Publishing
Release Date : 2025-02-19
Applications Of Multi Omics written by Richard Skiba and has been published by After Midnight Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-02-19 with Medical categories.
In the era of big data and personalized medicine, Applications of Multi-Omics serves as a comprehensive guide to integrating biological data across genomics, transcriptomics, proteomics, metabolomics, and epigenomics. This book explores how multi-omics technologies provide a holistic view of biological systems, transforming our understanding of human health, disease mechanisms, drug development, and environmental science. Written for researchers, healthcare professionals, and students in life sciences, this book breaks down complex concepts into accessible insights, covering key methodologies, computational approaches, and real-world applications. From precision medicine and biomarker discovery to AI-driven data integration and ethical considerations, Applications of Multi-Omics provides a deep dive into how multi-layered biological data is revolutionizing biomedical research and healthcare. Whether you are an academic researcher seeking to integrate multi-omics in your studies, a clinician exploring omics-driven diagnostics, or a data scientist working at the intersection of AI and life sciences, this book is an essential resource. It highlights emerging trends, challenges, and future directions in multi-omics, paving the way for groundbreaking discoveries in personalized medicine, biotechnology, and agricultural research. Join the multi-omics revolution and uncover the intricate biological networks shaping the future of science and medicine.
Transcriptome And Single Cell Sequencing Analyses To Classify Immune Subtypes Uncover Novel Biomarkers And Assess Immunotherapeutic Responses In Cancer
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Author : Hongda Liu
language : en
Publisher: Frontiers Media SA
Release Date : 2024-07-24
Transcriptome And Single Cell Sequencing Analyses To Classify Immune Subtypes Uncover Novel Biomarkers And Assess Immunotherapeutic Responses In Cancer written by Hongda Liu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-07-24 with Medical categories.
According to the most recent projections of the International Agency for Research on Cancer (IARC), there would be around 19.3 million new cases of cancer and 10 million cancer-related deaths globally in 2022. Cancer research has never halted. In particular, research into the cancer immunological microenvironment is gaining popularity.
Handbook Of Translational Transcriptomics
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Author : Anton Buzdin
language : en
Publisher: Academic Press
Release Date : 2025-05-16
Handbook Of Translational Transcriptomics written by Anton Buzdin and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-05-16 with Science categories.
Handbook of Translational Transcriptomics: Research, Protocols and Applications provides a comprehensive overview of the field of transcriptomics. With an emphasis on the various protocols and techniques available for investigation, it acts as a practical guide to researchers for implementing their own investigations in the field.This book begins with an overview of the past, present, and potential approaches in the field of transcriptomics, with discussions of choosing the correct approach based on the research needed. It also highlights the pros and cons of each approach. Following this, it explores techniques and protocols for investigating specific approaches focusing on RNA sequencing, expression arrays, and gene expression. It then delves into data analysis and offers recommendations, guidelines, and approaches related to data interpretation. This book also considers the translation of transcriptomics to clinical use and applications in molecular diagnostics, biomarkers in medicine, and personalized medicine specific to oncology, as well as biotechnology for pharmaceutical research.Handbook of Translational Transcriptomics: Research, Protocols and Applications is a detailed reference that provides a complete view of transcriptomics, ranging from methods to handling data and medical applications. This book is an invaluable guide for researchers working across molecular biology, genetics, bioinformatics and related fields, as well as graduate and PhD students in these areas. - Features practical guidance and protocols for researchers to replicate transcriptomic methods and techniques, including wet lab techniques. - Includes useful information on analyzing and interpreting transcriptomic data. - Offers a detailed introduction into translational transcriptomics, exploring both coding and noncoding RNAs including microRNA. - Investigates clinical implications of transcriptomics and applications to treating disease. - Considers some experimental and bioinformatic techniques in the field of transcriptomics, as well as more established approaches.
10 Years Of Frontiers In Genetics Past Discoveries Current Challenges And Future Perspectives
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Author : William C. Cho
language : en
Publisher: Frontiers Media SA
Release Date : 2023-06-02
10 Years Of Frontiers In Genetics Past Discoveries Current Challenges And Future Perspectives written by William C. Cho and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-02 with Science categories.
Single Cell Analysis
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Author : Tuhin Subhra Santra
language : en
Publisher: MDPI
Release Date : 2021-06-02
Single Cell Analysis written by Tuhin Subhra Santra and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-02 with Science categories.
Cells are the most fundamental building block of all living organisms. The investigation of any type of disease mechanism and its progression still remains challenging due to cellular heterogeneity characteristics and physiological state of cells in a given population. The bulk measurement of millions of cells together can provide some general information on cells, but it cannot evolve the cellular heterogeneity and molecular dynamics in a certain cell population. Compared to this bulk or the average measurement of a large number of cells together, single-cell analysis can provide detailed information on each cell, which could assist in developing an understanding of the specific biological context of cells, such as tumor progression or issues around stem cells. Single-cell omics can provide valuable information about functional mutation and a copy number of variations of cells. Information from single-cell investigations can help to produce a better understanding of intracellular interactions and environmental responses of cellular organelles, which can be beneficial for therapeutics development and diagnostics purposes. This Special Issue is inviting articles related to single-cell analysis and its advantages, limitations, and future prospects regarding health benefits.
Single Cell Omics Analyses In Cardiovascular Diseases
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Author :
language : en
Publisher: Frontiers Media SA
Release Date : 2024-05-14
Single Cell Omics Analyses In Cardiovascular Diseases written by and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-05-14 with Medical categories.
Single-cell OMICs analyses have recently become one of the most promising tools to probe biology at the cellular level, in large part due to its ability to address issues beyond the bulk analysis – a window into cellular heterogeneity. The ability to profile transcriptomic, epigenomic, proteomics, and metabolomics at the single cell level including more recently the spatial information has enhanced our ability to understand interactions between biomolecules in different contexts leading to the discovery of specific cellular subpopulations as well as biological mechanisms underlying pathologies which may be amenable to therapeutic interventions. The scale and availability of a variety of technologies to measure intricate molecular details have provided an impetus to research in many disease areas, including cardiovascular medicine.
Immunophysics And Immunoengineering
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Author : Jorge Bernardino De La Serna
language : en
Publisher: Frontiers Media SA
Release Date : 2020-03-30
Immunophysics And Immunoengineering written by Jorge Bernardino De La Serna and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-30 with categories.
ImmunoPhysics (ImmPhys) and ImmunoEngineering (ImmPhysEng), are two cross-disciplinary fields. ImmPhysEng aims to unravel quantitatively the immune-system function and regulation in health and disease. Whereas ImmPhys study and assess the physical basis of the immune response, ImmEng pursues its control and prediction. Ultimately, the overarching goal of these disciplines is to facilitate the development of therapeutic interventions to more precisely modulate and control the compromised immune response during diseases. Lately, these disciplines are becoming more popular and as such, the number of publications applying physical or engineering tools to understand the immune response is increasing. Nevertheless, there is still no scientific forum compiling the ImmPhysEng research breakthroughs. Possibly the biggest burden is to stimulate a fluent communication and syntony between a physicist or engineer and an immunologist.
Immunopathology Of Type 1 Diabetes
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Author : F. Susan Wong
language : en
Publisher: Frontiers Media SA
Release Date : 2022-03-28
Immunopathology Of Type 1 Diabetes written by F. Susan Wong and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-28 with Medical categories.
Multi Omics Analysis Of The Human Microbiome
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Author : Indra Mani
language : en
Publisher: Springer Nature
Release Date : 2024-05-29
Multi Omics Analysis Of The Human Microbiome written by Indra Mani and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-05-29 with Science categories.
This book introduces the rapidly evolving field of multi-omics in understanding the human microbiome. The book focuses on the technology used to generate multi-omics data, including advances in next-generation sequencing and other high-throughput methods. It also covers the application of artificial intelligence and machine learning algorithms to the analysis of multi-omics data, providing readers with an overview of the powerful computational tools that are driving innovation in this field. The chapter also explores the various bioinformatics databases and tools available for the analysis of multi-omics data. The book also delves into the application of multi-omics technology to the study of microbial diversity, including metagenomics, metatranscriptomics, and metaproteomics. The book also explores the use of these techniques to identify and characterize microbial communities in different environments, from the gut and oral microbiome to the skin microbiome and beyond. Towards theend, it focuses on the use of multi-omics in the study of microbial consortia, including mycology and the viral microbiome. The book also explores the potential of multi-omics to identify genes of biotechnological importance, providing readers with an understanding of the role that this technology could play in advancing biotech research. Finally, the book concludes with a discussion of the clinical applications of multi-omics technology, including its potential to identify disease biomarkers and develop personalized medicine approaches. Overall, this book provides readers with a comprehensive overview of this exciting field, highlighting the potential for multi-omics to transform our understanding of the microbial world.