Therapeutic Targets For Alzheimer S Disease
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Deciphering Drug Targets For Alzheimer S Disease
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Author : Dileep Kumar
language : en
Publisher: Springer Nature
Release Date : 2023-10-02
Deciphering Drug Targets For Alzheimer S Disease written by Dileep Kumar and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-02 with Medical categories.
This book explains the fundamental characteristics and biofunctionality of Alzheimer’s Disease drug targets and provides up-to-date information on the full range of their biomedical applications. An introductory section gives an overview of the recent developments related to drug targets identified and studied related to Alzheimer’s Disease and key developments from preclinical and clinical studies focusing on various molecular targets related to AD and dementia by subject experts all around the globe. Here, individual chapters address the progress and perspectives in human and non-human research, role of various biomarkers as an overview, advanced gene therapy, and novel compounds for therapeutic targets for Alzheimer’s disease. The book will be essential reading for graduate students, scientists, and engineers in any of the biomedical research fields in which efforts are being made to utilize novel drug targets and develop effective strategies for new drug targeting and delivery in Alzheimer’s disease treatment.
Alzheimer S Disease Pathogenesis
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Author : Suzanne De La Monte
language : en
Publisher: BoD – Books on Demand
Release Date : 2011-09-12
Alzheimer S Disease Pathogenesis written by Suzanne De La Monte and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-12 with Medical categories.
Alzheimer's Disease Pathogenesis: Core Concepts, Shifting Paradigms, and Therapeutic Targets, delivers the concepts embodied within its title. This exciting book presents the full array of theories about the causes of Alzheimer's, including fresh concepts that have gained ground among both professionals and the lay public. Acknowledged experts provide highly informative yet critical reviews of the factors that most likely contribute to Alzheimer's, including genetics, metabolic deficiencies, oxidative stress, and possibly environmental exposures. Evidence that Alzheimer's resembles a brain form of diabetes is discussed from different perspectives, ranging from disease mechanisms to therapeutics. This book is further energized by discussions of how neurotransmitter deficits, neuro-inflammation, and oxidative stress impair neuronal plasticity and contribute to Alzheimer's neurodegeneration. The diversity of topics presented in just the right depth will interest clinicians and researchers alike. This book inspires confidence that effective treatments could be developed based upon the expanding list of potential therapeutic targets.
Therapeutic Targets For Alzheimer S Disease
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Author : Magdalena J. Kiprowska
language : en
Publisher:
Release Date : 2016
Therapeutic Targets For Alzheimer S Disease written by Magdalena J. Kiprowska and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with categories.
Inflammasomes As Therapeutic Targets For Alzheimer S Disease
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Author :
language : en
Publisher:
Release Date : 2017
Inflammasomes As Therapeutic Targets For Alzheimer S Disease written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with categories.
Emerging Drugs And Targets For Alzheimer S Disease
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Author : Ana Martinez
language : en
Publisher: Royal Society of Chemistry
Release Date : 2010-05-07
Emerging Drugs And Targets For Alzheimer S Disease written by Ana Martinez and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-05-07 with Medical categories.
Alzheimer's disease is the most prevalent neurodegenerative disorder in the elderly. A recent study from the Bloomberg School of Public Health recently estimated that over 26 million people were living with the disease in 2006 and that the global prevalence of the disease will grow to 106 million by 2050. By that time, 43 per cent of those living with the disease will need high-level care, equivalent to that of a nursing home. However, even if modest advances in preventing or delaying the disease's progression were made, it could have a huge impact on global public health. According to this study, interventions that could delay the onset of the disease by as little as one year would reduce the prevalence of the disease by 12 million fewer cases in 2050. These figures reinforce how important it is to find an effective intervention for Alzheimer's disease. Emerging Drugs and Targets for Alzheimer's Disease collects some of the most outstanding examples of new drugs currently under pharmaceutical development or new targets in the validation process that will reach the Alzheimer's drug market over the next few years as disease modifying drugs. Written by a team of distinguished experts, these volumes are an essential resource for scientists in the pharmaceutical and biotechnology industries and academics working in the neurosciences field.
Alzheimer S Disease Drug Development
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Author : Jeffrey Cummings
language : en
Publisher: Cambridge University Press
Release Date : 2022-03-31
Alzheimer S Disease Drug Development written by Jeffrey Cummings and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-31 with Business & Economics categories.
Provides a definitive overview of the complex ecosystem facilitating Alzheimer's Disease drug research and development. Demonstrates a drug's journey from in the lab, clinical trial testing, regulatory review, and marketing by pharmaceutical companies. Details the use of artificial intelligence, clinical trial management, and financing models.
Neurodegenerative Diseases
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Author : Philip Beart
language : en
Publisher: Springer
Release Date : 2017-07-03
Neurodegenerative Diseases written by Philip Beart and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-03 with Medical categories.
Provides a timely overview of critical advances in molecular and cellular neurobiology, covers key methodologies driving progress, and highlights key future directions for research on neuronal injury and neurodegeneration relevant to neuronal brain pathologies. The editors bring together contributions from internationally recognized workers in the field to provide an up to date account of how and why molecular and cellular neurobiology is such an important area for clinical neuroscience. Understanding the molecular aspects of a number of neurodegenerative conditions such as Parkinson's or Alzheimer's disease for the purpose of improving patient management remains a major challenge of neurobiology be it from the basic or clinical perspective. A strategic evaluation of research contributions and the power of modern methods will help advance knowledge over the next years.
Amyloid Precursor Protein Secretases
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Author : Kalpita J. Patel
language : en
Publisher:
Release Date : 2000
Amyloid Precursor Protein Secretases written by Kalpita J. Patel and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with categories.
Alzheimer S Disease
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Author : Renee D. Wegrzyn
language : en
Publisher: CRC Press
Release Date : 2012-04-26
Alzheimer S Disease written by Renee D. Wegrzyn and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-04-26 with Medical categories.
In recent years, a tremendous amount of effort has been focused on better understanding the fundamentals of Alzheimer’s disease (AD) to facilitate early and accurate diagnosis and appropriately targeted therapeutic treatments. Alzheimer’s Disease: Targets for New Clinical, Diagnostic, and Therapeutic Strategies provides a detailed synopsis of the current state of the art of diagnostics and therapeutics and identifies emerging technologies and molecules that show promise in the management and treatment of AD. With contributions from experts drawn from academia, clinical practice, and the biotechnology and pharmaceutical industries, the book explores: The basis of AD and the role of Aβ oligomers in development of disease Existing and emerging in vitro biomarker-based methodologies for the diagnosis of AD, focusing on genetic, biochemical, and conformational strategies In vivo imaging diagnostic approaches Evolving diagnostic criteria, health regulatory guidelines, biomarkers in clinical trials, and available and emerging therapies Recent progress in small-molecule disease-modifier drug discovery efforts for AD, specifically in the areas of Aβ, tau, and emerging neuroprotective/neurorepair approaches How a case study of AD raises issues regarding clinical and pathologic criteria, risk factors, and the amyloid hypothesis The molecular conformational factors that govern the pathogenicity of aggregating proteins, and how these factors could represent new targets for disease-modifying therapies The latest epidemiological, pathological, biochemical, and behavioral studies that may shed some light on the risk of developing AD and similar dementias after traumatic brain injury Examining current hypotheses and suggesting possible new approaches to therapeutic clinical applications, this volume paves the way for a robust pipeline of therapeutics to combat not only AD, but a whole host of other neurodegenerative diseases.
Intramural Vascular Cells Key Therapeutic Targets For Vascular Cognitive Impairment
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Author : Roxana Octavia Carare
language : en
Publisher: Frontiers Media SA
Release Date : 2020-12-31
Intramural Vascular Cells Key Therapeutic Targets For Vascular Cognitive Impairment written by Roxana Octavia Carare and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-31 with Science categories.
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.