Tryptophan Metabolism Implications For Biological Processes Health And Disease


Tryptophan Metabolism Implications For Biological Processes Health And Disease
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Tryptophan Metabolism Implications For Biological Processes Health And Disease


Tryptophan Metabolism Implications For Biological Processes Health And Disease
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Author : Atilla Engin
language : en
Publisher: Humana Press
Release Date : 2015-04-28

Tryptophan Metabolism Implications For Biological Processes Health And Disease written by Atilla Engin and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-28 with Medical categories.


This book discusses the relationship between cellular immunity and tryptophan metabolism, as well as its products, serotonin and melatonin, in the development of several diseases and reappraises the common signal transduction pathways of the neurodegenerative diseases, carcinogenesis, immune tolerance, inflammation, hypersensitivity reactions, neuropsychiatric disorders, in addition to bacterial tryptophan biosynthesis and novel antimicrobials. Tryptophan Metabolism: Implications for Biological Processes, Health and Disease presents fundamental information on tryptophan related metabolic pathways and metabolites, implications of these products for specific biological processes, diseases and conditions. This book focuses on effects of tryptophan metabolites on human health and will appeal to researchers, clinicians and students within this field.



Developments In Tryptophan And Serotonin Metabolism


Developments In Tryptophan And Serotonin Metabolism
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Author : Graziella Allegri
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Developments In Tryptophan And Serotonin Metabolism written by Graziella Allegri and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.


This volume contains the proceedings of the Tenth International Meeting of the International Study Group for Tryptophan Research (ISTR V), held at the University of Padova, Padova, Italy, from 25-29 June, 2002 under the auspices of the Ministry of Education, University and Research (MIUR) in Roma, the University of Padova, the Italian Chemical Society - Division of Pharmaceutical Chemistry, the Veneto Region and the City of Padova. The meeting was organized to cover the recent developments in the field of tryptophan research. Weare very honoured that so many speakers accepted our invitation to give plenary lectures which, with the other communications, demonstrated the high scientific value of the Meeting. The publications in this volume are subdivided into nine main chapters, and cover all the major aspects in immunology, neurobiology, psychiatry, pathology, clinics, metabolism, enzymology, pharmacology, toxicology, melatonin, exercise and analytical chemistry. The volume includes the contributions of 325 scientists from 24 countries, and the Musajo Memorial Lecture delivered by Prof. Osamu Hayaishi during the Opening Ceremony.



Tryptophan


Tryptophan
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Author : Herschel Sidransky
language : en
Publisher: CRC Press
Release Date : 2001-11-21

Tryptophan written by Herschel Sidransky and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-11-21 with Medical categories.


Historically, the amino acid tryptophan has been considered to play a role in cancer development and the aging process. In recent times, this nutrient has been associated with eosinophila myalgia syndrome - a new human disease that attacks the muscular system. This detailed book examines the implications of the large measure of fresh information ga



Hormones Metabolism And The Benefits Of Exercise


Hormones Metabolism And The Benefits Of Exercise
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Author : Bruce Spiegelman
language : en
Publisher: Springer
Release Date : 2018-03-07

Hormones Metabolism And The Benefits Of Exercise written by Bruce Spiegelman and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-07 with Science categories.


The world is faced with an epidemic of metabolic diseases such as obesity and type 2 diabetes. This is due to changes in dietary habits and the decrease in physical activity. Exercise is usually part of the prescription, the first line of defense, to prevent or treat metabolic disorders. However, we are still learning how and why exercise provides metabolic benefits in human health. This open access volume focuses on the cellular and molecular pathways that link exercise, muscle biology, hormones and metabolism. This will include novel “myokines” that might act as new therapeutic agents in the future.



Targeting The Broadly Pathogenic Kynurenine Pathway


Targeting The Broadly Pathogenic Kynurenine Pathway
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Author : Sandeep Mittal
language : en
Publisher: Springer
Release Date : 2016-08-23

Targeting The Broadly Pathogenic Kynurenine Pathway written by Sandeep Mittal and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-23 with Science categories.


Tryptophan metabolism via kynurenine pathway plays a critical role in both health and a variety of human diseases. This book highlights the known associations between kynurenine pathway and various disease states, as well as examines the current status of drug development and clinical trials of compounds known to alter tryptophan metabolism. The research plays a critical role in molecular targeted therapies directed at altering the kynurenine pathway of tryptophan metabolism. The initial and rate-limiting step of tryptophan metabolism is mediated by one of two enzymes, tryptophan-2,3-dioxygenase (TDO; predominantly in the liver, but also in the brain) and indoleamine-2,3-dioxygenase (IDO; in a host of tissues in response to immune activation). Targeting the enzymes IDO and TDO, as well as other downstream effectors would therefore be likely to generate novel treatment options that would be helpful in a wide variety of clinical settings. This book provides a unique bridge between basic mechanistic understanding of the role of the kynurenine pathway with translational applications and clinical relevance. It will explore the indications that tryptophan metabolism is a potential biomarker of disease activity, can contribute to local and possibly systemic immune suppression in cancer, and is an attractive target for which a variety of inhibitors are readily available.



Kynurenine And Serotonin Pathways


Kynurenine And Serotonin Pathways
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Author : Robert Schwarcz
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09

Kynurenine And Serotonin Pathways written by Robert Schwarcz and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Medical categories.


Proceedings of the International Study Group for Tryptophan Research: Sixth International Meeting, held in Baltimore, Maryland, May 9--12, 1989



Inflammation In Psychiatry


Inflammation In Psychiatry
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Author : A. Halaris
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2013-02-27

Inflammation In Psychiatry written by A. Halaris and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-02-27 with Medical categories.


Psychoimmunology is a rapidly maturing area of scientific endeavor that provides a compelling integrative link between the immune system and its response to stress and psychiatric illness. Stress initiates pathological changes by activating the immune and endocrine systems. Inflammation is at the core of the complex and interactive systems that both contribute to and result from psychopathology. Consequently, inflammation research advances our knowledge of the pathology of depression, schizophrenia, chronic fatigue syndrome, posttraumatic stress disorder and a host of co-morbid conditions, notably diabetes, cardiovascular disease and cerebrovascular disease. The possible mechanisms underlying the bidirectionality of co-morbid medical and psychiatric disorders can be viewed as a consequence of inflammatory changes. These emerging novel concepts illustrate how the knowledge of inflammation can enable meaningful integration of psychopathology with physical co-morbidity. The innovative articles in this volume highlight the intricate link between psychiatry and psychoimmunology and underscore the central role of inflammation in furthering our understanding of the pathophysiology underlying mental health and illness.



Senescence


Senescence
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Author : Jolanta Dorszewska
language : en
Publisher: BoD – Books on Demand
Release Date : 2017-08-30

Senescence written by Jolanta Dorszewska and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-30 with Medical categories.


In the second half of the twentieth century, life expectancy was prolonged, and the number of elderly people increased. The effect of population aging increases in the frequency of neurodegenerative diseases such as Alzheimer's and Parkinson's diseases, epilepsy, and stroke. Also, a higher incidence of infections, autoimmune diseases, and malignant cancers is observed in elderly people. The aging process is difficult to define. Are physiological changes in elderly people controlled by specific genes? Is aging process a pathophysiology affecting different organs with different severity? Finding answers to these questions may help prevent age-related diseases and improve the quality of life of old people. This book was made as a compendium on contemporary challenges in senescence.



Impact Of Microbiome On Gut Mucosal Immunity In Health And Disease


Impact Of Microbiome On Gut Mucosal Immunity In Health And Disease
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Author : Oscar Gilberto Gomez-Duarte
language : en
Publisher: Frontiers Media SA
Release Date : 2022-11-07

Impact Of Microbiome On Gut Mucosal Immunity In Health And Disease written by Oscar Gilberto Gomez-Duarte and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-07 with Medical categories.




Biophotonics Tryptophan And Disease


Biophotonics Tryptophan And Disease
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Author : Laura A. Sordillo
language : en
Publisher: Academic Press
Release Date : 2021-10-09

Biophotonics Tryptophan And Disease written by Laura A. Sordillo and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-09 with Science categories.


Biophotonics, Tryptophan and Disease is a comprehensive resource on the key role of tryptophan in wide range of diseases as seen by using optics techniques. It explores the use of fluorescence spectroscopy, Raman, imaging techniques and time-resolved spectroscopy in normal and diseased tissues and shows the reader how light techniques (i.e. spectroscopy and imaging) can be used to detect, distinguish and evaluate diseases. Diseases covered include cancer, neurodegenerative diseases and other age-related diseases. Biophotonics, Tryptophan and Disease offers a clear presentation of techniques and integrates material from different disciplines into one resource. It is a valuable reference for students and interdisciplinary researchers working on the interface between biochemistry and molecular biology, translational medicine, and biophotonics. Shows the key role of tryptophan in diseases Emphasizes how optical techniques can be potent means of assessing many diseases Points to new ways of understanding autism, aging, depression, cancer and neurodegenerative diseases