Tumor Associated Fibroblasts And Their Matrix
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Tumor Associated Fibroblasts And Their Matrix
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Author : Margareta M. Mueller
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-07-28
Tumor Associated Fibroblasts And Their Matrix written by Margareta M. Mueller and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-07-28 with Medical categories.
During the last 20 years it has become increasingly clear that the tumor micro-environment, the tumor stroma with its cellular end extracellular components, plays an crucial role in regulating tumor growth and progression. This book on “Tumor-associated fibroblasts and their matrix” as part of the series on “Tumor-Microenvironment” is the first comprehensive discussion of these two main players of the tumor microenvironment. The best experts in this new area of tumor research and therapy review the role of these major components in the tumor stroma in the process of tumor development and progression. They discuss their interaction with other players such as blood vessels and immune cells, and show novel perspectives for tumor therapy. This compilation of excellent contributions of the best known experts in this important field in cancer research and therapy is a must for all scientists engaged in basic and clinical research. Increasing evidence of successful targeting of both cellular and matrix components in tumor therapy renders this book of particular interest for scientists engaged in pharmaceutical industry searching for new components for cancer therapy.
Biomarkers Of The Tumor Microenvironment
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Author : Lars A. Akslen
language : en
Publisher: Springer Nature
Release Date : 2022-07-12
Biomarkers Of The Tumor Microenvironment written by Lars A. Akslen and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-12 with Medical categories.
This book reviews different aspects of the cancer microenvironment, and its regulation and importance for tumor progression. Methodological advancements and practical applications, in terms of how biomarkers are studied and increasingly included in clinical trials and therapy protocols, are described and discussed. Biomarkers of the Tumor Microenvironment is an educational resource for students and members of the cancer research community as a whole, especially for those using morphology analysis techniques and models focusing on the cross-talk between different cell types in tumors. The textbook provides a comprehensive overview of the microenvironment in various contexts from the perspectives of experienced and accomplished cancer researchers and clinicians.
Encyclopedia Of Cancer
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Author : Manfred Schwab
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-09-23
Encyclopedia Of Cancer written by Manfred Schwab and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-09-23 with Medical categories.
This comprehensive encyclopedic reference provides rapid access to focused information on topics of cancer research for clinicians, research scientists and advanced students. Given the overwhelming success of the first edition, which appeared in 2001, and fast development in the different fields of cancer research, it has been decided to publish a second fully revised and expanded edition. With an A-Z format of over 7,000 entries, more than 1,000 contributing authors provide a complete reference to cancer. The merging of different basic and clinical scientific disciplines towards the common goal of fighting cancer makes such a comprehensive reference source all the more timely.
Second Harmonic Generation Imaging
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Author : Francesco S. Pavone
language : en
Publisher: Taylor & Francis
Release Date : 2016-04-19
Second Harmonic Generation Imaging written by Francesco S. Pavone and has been published by Taylor & Francis this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Science categories.
Second-harmonic generation (SHG) microscopy has shown great promise for imaging live cells and tissues, with applications in basic science, medical research, and tissue engineering. Second Harmonic Generation Imaging offers a complete guide to this optical modality, from basic principles, instrumentation, methods, and image analysis to biomedical a
The Tumor Stroma
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Author : Jai Prakash
language : en
Publisher: CRC Press
Release Date : 2022-01-27
The Tumor Stroma written by Jai Prakash and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-27 with Medical categories.
The identification of the role of tumor stroma—the tissue in the surroundings of cancer cells—in cancer development, progression, and metastasis has revolutionized the fields of cancer biology as well as cancer therapeutics. This book provides a comprehensive overview of this rapidly-evolving field including tumor stroma biology, therapeutic targets, molecular imaging, and advanced tumor stroma in vitro models. The book will serve as a handbook for graduate students, postgraduate researchers, pharmaceutical scientists, and biomedical engineers.
Muscle 2 Volume Set
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Author : Joseph Hill
language : en
Publisher: Academic Press
Release Date : 2012-08-29
Muscle 2 Volume Set written by Joseph Hill and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-08-29 with Science categories.
A valuable study of the science behind the medicine, Muscle: Fundamental Biology and Mechanisms of Disease brings together key leaders in muscle biology. These experts provide state-of-the-art insights into the three forms of muscle--cardiac, skeletal, and smooth--from molecular anatomy, basic physiology, disease mechanisms, and targets of therapy. Commonalities and contrasts among these three tissue types are highlighted. This book focuses primarily on the biology of the myocyte. Individuals active in muscle investigation--as well as those new to the field--will find this work useful, as will students of muscle biology. In the case of hte former, many wish to grasp issues at the margins of their own expertise (e.g. clinical matters at one end; molecular matters at the other), adn this book is designed to assist them. Students, postdoctoral fellows, course directors and other faculty will find this book of interest. Beyond this, many clinicians in training (e.g. cardiology fellows) will benefit. - The only resource to focus on science before the clinical work and therapeutics - Tiered approach to subject: discussion first of normal muscle function through pathological/disease state changes, and ending each section with therapeutic interventions - Coverage of topics ranging from basic physiology to newly discovered molecular mechanisms of muscle diseases for all three muscle types: cardiac, skeletal, and smooth
Epigenetic Regulation Of Cancer Part A
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Author :
language : en
Publisher: Elsevier
Release Date : 2023-09-02
Epigenetic Regulation Of Cancer Part A written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-02 with Science categories.
In Epigenetic Regulation of Cancer, a series of volumes from the International Review of Cell and Molecular Biology series, various experts in epigenetics critically cover multiple facets of cancer-associated epigenetic alterations, including the impact of epigenetic deregulation in all steps of oncogenesis as well as promising strategies to therapeutically target cancer-associated epigenetic deregulation. This collection aims at expanding our knowledge on this exciting field of investigation and providing fresh insights as a basis for further investigations that will hopefully translate into an improved clinical management of patients with cancer. - The collection provides accurate and critical review articles from invited experts on the selected topic - Each review provides the newest insights and remarks on multiple subjects of the topic - The volume offers a broad range of perspectives on detailed features
Handbook Of Proteases In Cancer
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Author : Sajal Chakraborti
language : en
Publisher: CRC Press
Release Date : 2024-12-13
Handbook Of Proteases In Cancer written by Sajal Chakraborti and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-12-13 with Science categories.
This handbook provides comprehensive coverage of the role of proteases and the associated biochemical pathways in cancer development and metastasis. Proteases make up about 2% of the human genome and play a critical role in the tumor microenvironment. Handbook of Proteases in Cancer: Cellular and Molecular Aspects introduces the major classes of proteases and the signal transduction mechanisms associated with cancer initiation and progression. It discusses the role of inflammation and immune responses in proteases-induced cancer. The book covers cancer-induced gene expression and apoptotic and necrotic pathways in cancer. This is useful for researchers and professionals in cancer research, biochemistry, and physiology. Key Features • Provides insights on the roles of proteases and anti-proteases in the tumor microenvironment. • Covers various cancer-induced apoptotic and necrotic pathways. • Discusses the mechanisms by which proteases induce an increase in inflammation, immune response, and gene expression. • Covers the function of protease-activated receptors in cancer. • Reviews the different gene expression pathways and the ways they become erratic during protease-induced cancer.
Nanotechnology And Regenerative Engineering
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Author : Cato T. Laurencin
language : en
Publisher: CRC Press
Release Date : 2014-10-28
Nanotechnology And Regenerative Engineering written by Cato T. Laurencin and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-28 with Medical categories.
Nanotechnology and regenerative engineering have emerged to the forefront as the most versatile and innovative technologies to foster novel therapeutic techniques and strategies of the twenty-first century. The first edition of Nanotechnology and Tissue Engineering: The Scaffold was the first comprehensive source to explain the developments in nano
Pathologic Basis Of Veterinary Disease Expert Consult E Book
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Author : James F. Zachary
language : en
Publisher: Elsevier Health Sciences
Release Date : 2016-05-23
Pathologic Basis Of Veterinary Disease Expert Consult E Book written by James F. Zachary and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-05-23 with Medical categories.
Diagnose and manage diseases using the newest information and research! Pathologic Basis of Veterinary Disease – Expert Consult, 6th Edition provides complete, illustrated coverage of both general pathology and the pathology of organ systems of domestic animals. Addressing species from dogs and cats to pigs and cattle — and many more — this reference describes the lesions and pathogeneses of diseases, how cells and tissues respond to injury, and the interplay of host defense mechanisms with microbes and injurious agents. Updates include the latest scientific advances and diagnostic information. Written by a team of expert contributors, this book includes an Expert Consult website with access to the complete digital book plus thousands of images and guidelines for sample acquisition and for performing a complete necropsy. - Complete coverage of both general pathology and pathology of organ systems is provided in one convenient resource, and includes the latest information available. - Over 20 recognized experts deliver the most relevant information for the practitioner, student, or individual preparing for the American College of Veterinary Pathology board examination. - UPDATED content on cellular and organ system pathology includes the latest insights into the science of inflammation, healing, and molecular carcinogenesis, as well as expanded coverage of genetics and disease. - Over 2,100 full-color illustrations include color schematics, flow charts, and diagrammatic representations of disease processes as well as summary tables and boxes, making it easier to understand difficult concepts. - Clear, up-to-date explanations of disease mechanisms describe cell, tissue, and organ response to injury and infection. - Easy-to-follow organization for each systemic disease chapter includes a brief review of basic principles related to anatomy, structure, and function, followed by congenital and functional abnormalities and discussions of infectious disease responses, helping you apply principles to veterinary practice. - Expert Consult website provides the reader with the complete digital text plus: An image collection; guidelines for performing a complete, systematic necropsy and appropriate sample acquisition for all organ systems; a comprehensive glossary; and an appendix of photographic techniques in veterinary pathology. - NEW line drawings and schematic diagrams depict current concepts about pathogeneses and lesions of veterinary diseases. - NEW! Essential Concept boxes in each basic pathology chapter break down long and complicated topics, making it easier to understand lesions and pathogeneses in the 'organ system' chapters. - NEW! Key Readings Index at the beginning of each chapter includes page numbers, making important information easy to locate.