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Non Coding Rnas And Cancer

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Long Non Coding Rnas In Cancer

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Author : Alfons Navarro
language : en
Publisher: Humana
Release Date : 2021-06-24

Long Non Coding Rnas In Cancer written by Alfons Navarro and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-24 with Medical categories.

This volume presents techniques needed for the study of long non-coding RNAs (lncRNAs) in cancer from their identification to functional characterization. Chapters guide readers through identification of lncRNA expression signatures in cancer tissue or liquid biopsies by RNAseq, single Cell RNAseq, Phospho RNAseq or Nanopore Sequencing techniques; validation of lncRNA signatures by Real time PCR, digital PCR or in situ hybridization; and functional analysis by siRNA or CRISPR based methods for lncRNA silencing or overexpression. Lipid based nanoparticles for delivery of siRNAs in vivo, lncRNA-protein interactions, viral lncRNAs and circRNAs are also treated in this volume. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and practical, Long Non-Coding RNAs in Cancer aims to provide a collection of laboratory protocols, bioinformatic pipelines, and review chapters to further research in this vital field.

The Long And Short Non Coding Rnas In Cancer Biology

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Author : Erwei Song
language : en
Publisher: Springer
Release Date : 2016-07-04

The Long And Short Non Coding Rnas In Cancer Biology written by Erwei Song and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-07-04 with Medical categories.

The book conveys a comprehensive knowledge of long and short ncRNAs in cancer regulation and their potentials as diagnostic biomarkers and therapeutic targets. Topics covered include the molecular mechanisms of various classes of ncRNAs (with emphasis on long non-coding RNAs and microRNAs) in cancer, the functional roles of ncRNAs in regulating different cancer hallmarks (including proliferation, apoptosis, stem-cell properties, epithelial-mesenchymal transition, metabolism, angiogenesis, tumor-host interactions and therapeutic resistance), the role of ncRNAs in regulating cancer signaling circuitry programs (highlighting their involvement in c-myc, p53 and NFkB signaling), a systemic summary of clinical and preclinical studies that evaluate the potential of ncRNA signatures for cancer diagnosis and prognosis and strategies to delivery short ncRNAs as therapeutic molecules for cancer treatment. This book may serve as a comprehensive resource for researchers, graduate students and oncologists in ncRNA and cancer research and help drug development by identifying ncRNA targets.

Non Coding Rnas And Cancer

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Author : Muller Fabbri
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-10-28

Non Coding Rnas And Cancer written by Muller Fabbri and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-28 with Medical categories.

The discovery of microRNAs and its role as gene expression regulators in human carcinogenesis represents one of the most important scientific achievements of the last decade. More recently, other non-coding RNAs have been discovered and its implications in cancer are emerging as well, suggesting a broader than anticipated involvement of the non-coding genome in cancer. Moreover, completely new and unexpected functions for microRNAs are being revealed, leading to the identification of new anticancer molecular targets. This book represents a comprehensive guide on non-coding RNAs and cancer, spanning from its role as cancer biomarkers, to providing the most useful bioinformatic tools, to presenting some of the most relevant discoveries, which indicates how these fascinating molecules act as fine orchestrators of cancer biology.

Clinical Applications Of Noncoding Rnas In Cancer

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Author : Subash Gupta
language : en
Publisher: Academic Press
Release Date : 2022-01-19

Clinical Applications Of Noncoding Rnas In Cancer written by Subash Gupta and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-19 with Science categories.

Clinical Applications of Noncoding RNAs in Cancer summarizes the existing strategies, advances, and future opportunities on the role of noncoding RNAs in cancer patients. Established clinicians and researchers from all around the world share their views and expertise and provide readers with invaluable knowledge on the subject. This book provides a comprehensive collection of information on the utility of noncoding RNAs in the diagnosis, prognosis, and therapy of cancer. It also discusses the evolutionary significance of noncoding RNAs and how the molecular tools such as RNA-seq, RNA-FISH, ic-SHAPE, and quantitative real-time PCR help in the detection and elucidation of the functions of noncoding RNAs. Additionally, the challenges associated with noncoding RNA approaches and future developments are discussed. It is a valuable resource for cancer researchers, oncologists, clinicians, and other biomedical field members who want to learn more about noninvasive ways to diagnose and efficiently treat diverse cancer types. - Presents a beginning chapter summary to help readers understand the content thoroughly - Encompasses detailed description of information from clinical studies on noncoding RNAs in cancer therapy - Discusses one cancer type per chapter making the content easy to reference

Roles Of Non Coding Rnas In Tumor Growth And Development

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Author : Giovanni Blandino
language : en
Publisher: Frontiers Media SA
Release Date : 2023-01-05

Roles Of Non Coding Rnas In Tumor Growth And Development written by Giovanni Blandino and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-05 with Medical categories.

Long Non Coding Rnas In Cancer

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Author : Alfons Navarro
language : en
Publisher: Humana
Release Date : 2022-06-25

Long Noncoding Rnas In Plants

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Author : Santosh Kumar Upadhyay
language : en
Publisher: Academic Press
Release Date : 2020-11-13

Long Noncoding Rnas In Plants written by Santosh Kumar Upadhyay and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-13 with Science categories.

The growth of human population has increased the demand for improved yield and quality of crops and horticultural plants. However, plant productivity continues to be threatened by stresses such as heat, cold, drought, heavy metals, UV radiations, bacterial and fungal pathogens, and insect pests. Long noncoding RNAs are associated with various developmental pathways, regulatory systems, abiotic and biotic stress responses and signaling, and can provide an alternative strategy for stress management in plants. Long Noncoding RNAs in Plants: Roles in development and stress provides the most recent advances in LncRNAs, including identification, characterization, and their potential applications and uses. Introductory chapters include the basic features and brief history of development of lncRNAs studies in plants. The book then provides the knowledge about the lncRNAs in various important agricultural and horticultural crops such as cereals, legumes, fruits, vegetables, and fiber crop cotton, and their roles and applications in abiotic and biotic stress management. - Includes the latest advances and research in long noncoding RNAs in plants - Provides alternative strategies for abiotic and biotic stress management in horticultural plants and agricultural crops - Focuses on the application and uses of long noncoding RNAs

Non Coding Rnas In Colorectal Cancer

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Author : Ondrej Slaby
language : en
Publisher: Springer
Release Date : 2016-08-29

Non Coding Rnas In Colorectal Cancer written by Ondrej Slaby and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-29 with Medical categories.

This is the first book to provide a broad framework for obtaining an in depth understanding of the state-of-the-art knowledge on abnormalities of non-coding RNAs found to be associated with colorectal cancer pathogenesis. Readers will discover possible mechanisms underlying the substantial roles played by non-coding RNAs in molecular hallmarks of colorectal cancer. This work further provides the comprehensive overview and novel insights into using of non-coding RNAs as colorectal cancer biomarkers enabling early detection of the disease, prognostic stratification of the patients and prediction of therapeutic response. The reader is introduced to the overview of modern non-coding RNAs-based therapeutic strategies, and summary of their preclinical testing performed in colorectal cancer. The work is written for researchers who want to explore current state of the knowledge in this interesting field of molecular oncology.

Combating Cancer With Natural Products What Would Non Coding Rnas Bring

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Author : Yongye Huang
language : en
Publisher: Frontiers Media SA
Release Date : 2021-11-05

Combating Cancer With Natural Products What Would Non Coding Rnas Bring written by Yongye Huang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-05 with Medical categories.

Advances In Non Coding Rnas In Cancer Biology And Immunology

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Author : Shuai Jiang
language : en
Publisher: Academic Press
Release Date : 2022-05-15

Advances In Non Coding Rnas In Cancer Biology And Immunology written by Shuai Jiang and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-15 with Medical categories.

Advances in Non-coding RNAs in Cancer-Biology and Immunology is a resource for three major types of non-coding RNAs including microRNA, LnRNA and piRNA. It covers machinery of non-coding RNAs, including microRNA, LnRNA and piRNA, and the identification of targets of these non-coding RNAs, and the identification of physiological and pathological roles of miRNAs, LnRNAs and piRNAs in immunology and cancer biology. The aberrant expressions of these non-coding RNAs within the cells cause various abnormalities and diseases including cancer and immune system-associated diseases. Manipulating their aberrant expression or function can serve as potential novel diagnostic/prognostic biomarkers and bring in new therapeutic strategies for multiple human diseases. This can be further translated from bench-side to clinic for improving human health. Advances in Non-coding RNAs in Cancer-Biology and Immunology introduces basic ideas of miRNAs, LnRNAs and piRNAs, along with their detailed bio-processing steps, critical functions in the development of tumorigenesis and controlling immune cell responses, which benefits for identifying different classes of non-coding RNAs and their targets, identifying new members of these non-coding RNAs and predicting the possible functions of these molecules. It captures the essence of the pioneering work of some of the world's leading researchers showcasing the scientific excitements surrounding the evolving regulatory roles of miRNAs, LnRNAs, piRNAs highlighting their potential towards the diagnosis and therapeutics of various diseases. Provides a unified cutting-edge resource for non-coding RNAs including miRNAs LnRNAs, and piRNAs, their physiological and pathological roles and potential applications Showcases high-throughput technologies and other approaches for discovery of these non-coding RNAs and their downstream targets Unveils the diverse molecular mechanisms by which miRNAs, LnRNAs and piRNAs regulate gene expression in animal cells Showcases recent discoveries on involvement of these non-coding RNAs in different biological processes and diseases as well as their possible use in diagnosis Reports breakthroughs in the use of these non-coding RNAs for diagnosis and personalized therapy

Non Coding Rnas And Cancer

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