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Clinical Applications Of Noncoding Rnas In Cancer


Clinical Applications Of Noncoding Rnas In Cancer
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Clinical Applications Of Noncoding Rnas In Cancer


Clinical Applications Of Noncoding Rnas In Cancer
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Author : Subash Gupta
language : en
Publisher: Academic Press
Release Date : 2022-01-19

Clinical Applications Of Noncoding Rnas In Cancer written by Subash Gupta and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-19 with Science categories.


Clinical Applications of Noncoding RNAs in Cancer summarizes the existing strategies, advances, and future opportunities on the role of noncoding RNAs in cancer patients. Established clinicians and researchers from all around the world share their views and expertise and provide readers with invaluable knowledge on the subject. This book provides a comprehensive collection of information on the utility of noncoding RNAs in the diagnosis, prognosis, and therapy of cancer. It also discusses the evolutionary significance of noncoding RNAs and how the molecular tools such as RNA-seq, RNA-FISH, ic-SHAPE, and quantitative real-time PCR help in the detection and elucidation of the functions of noncoding RNAs. Additionally, the challenges associated with noncoding RNA approaches and future developments are discussed. It is a valuable resource for cancer researchers, oncologists, clinicians, and other biomedical field members who want to learn more about noninvasive ways to diagnose and efficiently treat diverse cancer types. - Presents a beginning chapter summary to help readers understand the content thoroughly - Encompasses detailed description of information from clinical studies on noncoding RNAs in cancer therapy - Discusses one cancer type per chapter making the content easy to reference



Clinical Applications Of Noncoding Rnas In Cancer


Clinical Applications Of Noncoding Rnas In Cancer
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Author : Subash Gupta
language : en
Publisher: Elsevier
Release Date : 2022-01-24

Clinical Applications Of Noncoding Rnas In Cancer written by Subash Gupta and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-24 with Science categories.


Clinical Applications of Noncoding RNAs in Cancer summarizes the existing strategies, advances, and future opportunities on the role of noncoding RNAs in cancer patients. Established clinicians and researchers from all around the world share their views and expertise and provide readers with invaluable knowledge on the subject. This book provides a comprehensive collection of information on the utility of noncoding RNAs in the diagnosis, prognosis, and therapy of cancer. It also discusses the evolutionary significance of noncoding RNAs and how the molecular tools such as RNA-seq, RNA-FISH, ic-SHAPE, and quantitative real-time PCR help in the detection and elucidation of the functions of noncoding RNAs. Additionally, the challenges associated with noncoding RNA approaches and future developments are discussed. It is a valuable resource for cancer researchers, oncologists, clinicians, and other biomedical field members who want to learn more about noninvasive ways to diagnose and efficiently treat diverse cancer types. Presents a beginning chapter summary to help readers understand the content thoroughly Encompasses detailed description of information from clinical studies on noncoding RNAs in cancer therapy Discusses one cancer type per chapter making the content easy to reference



Long Non Coding Rnas In Cancer


Long Non Coding Rnas In Cancer
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Author : Alfons Navarro
language : en
Publisher: Humana
Release Date : 2021-06-24

Long Non Coding Rnas In Cancer written by Alfons Navarro and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-24 with Medical categories.


This volume presents techniques needed for the study of long non-coding RNAs (lncRNAs) in cancer from their identification to functional characterization. Chapters guide readers through identification of lncRNA expression signatures in cancer tissue or liquid biopsies by RNAseq, single Cell RNAseq, Phospho RNAseq or Nanopore Sequencing techniques; validation of lncRNA signatures by Real time PCR, digital PCR or in situ hybridization; and functional analysis by siRNA or CRISPR based methods for lncRNA silencing or overexpression. Lipid based nanoparticles for delivery of siRNAs in vivo, lncRNA-protein interactions, viral lncRNAs and circRNAs are also treated in this volume. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and practical, Long Non-Coding RNAs in Cancer aims to provide a collection of laboratory protocols, bioinformatic pipelines, and review chapters to further research in this vital field.



Long Non Coding Rnas Function Mechanisms And Applications


Long Non Coding Rnas Function Mechanisms And Applications
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Author :
language : en
Publisher: BoD – Books on Demand
Release Date : 2025-07-02

Long Non Coding Rnas Function Mechanisms And Applications written by and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-07-02 with Science categories.


LncRNAs contribute to cancer progression by regulating gene expression epigenetically and post-transcriptionally. They influence tumorigenesis through interactions with chromatin modifiers, act as competitive endogenous RNAs to modulate microRNA activity and regulate processes such as epithelial-mesenchymal transition (EMT) that facilitate metastasis. LncRNAs affect cancer cell proliferation, apoptosis, migration, metabolism, and drug resistance, making them crucial players in tumor development and potential targets for diagnosis and therapy. The book covers the latest reports about lncRNAs.



Human And Oncoviral Noncoding Rnas As Modulators Of Cancer Aggressiveness And Disease Progression


Human And Oncoviral Noncoding Rnas As Modulators Of Cancer Aggressiveness And Disease Progression
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Author : Deilson Elgui De Oliveira
language : en
Publisher: Frontiers Media SA
Release Date : 2021-03-05

Human And Oncoviral Noncoding Rnas As Modulators Of Cancer Aggressiveness And Disease Progression written by Deilson Elgui De Oliveira and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-05 with Science categories.




The Long And Short Non Coding Rnas In Cancer Biology


The Long And Short Non Coding Rnas In Cancer Biology
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Author : Erwei Song
language : en
Publisher: Springer
Release Date : 2016-07-04

The Long And Short Non Coding Rnas In Cancer Biology written by Erwei Song and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-07-04 with Medical categories.


The book conveys a comprehensive knowledge of long and short ncRNAs in cancer regulation and their potentials as diagnostic biomarkers and therapeutic targets. Topics covered include the molecular mechanisms of various classes of ncRNAs (with emphasis on long non-coding RNAs and microRNAs) in cancer, the functional roles of ncRNAs in regulating different cancer hallmarks (including proliferation, apoptosis, stem-cell properties, epithelial-mesenchymal transition, metabolism, angiogenesis, tumor-host interactions and therapeutic resistance), the role of ncRNAs in regulating cancer signaling circuitry programs (highlighting their involvement in c-myc, p53 and NFkB signaling), a systemic summary of clinical and preclinical studies that evaluate the potential of ncRNA signatures for cancer diagnosis and prognosis and strategies to delivery short ncRNAs as therapeutic molecules for cancer treatment. This book may serve as a comprehensive resource for researchers, graduate students and oncologists in ncRNA and cancer research and help drug development by identifying ncRNA targets.



Roles Of Non Coding Rnas In Tumor Growth And Development


Roles Of Non Coding Rnas In Tumor Growth And Development
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Author : Giovanni Blandino
language : en
Publisher: Frontiers Media SA
Release Date : 2023-01-05

Roles Of Non Coding Rnas In Tumor Growth And Development written by Giovanni Blandino and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-05 with Medical categories.




Combating Cancer With Natural Products Non Coding Rna And Rna Modification


Combating Cancer With Natural Products Non Coding Rna And Rna Modification
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Author : Yongye Huang
language : en
Publisher: Frontiers Media SA
Release Date : 2023-03-15

Combating Cancer With Natural Products Non Coding Rna And Rna Modification written by Yongye Huang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-15 with Science categories.




The Role Of Non Coding Rnas In Gastrointestinal Cancers


The Role Of Non Coding Rnas In Gastrointestinal Cancers
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Author : Kanjoormana Aryan Manu
language : en
Publisher: Frontiers Media SA
Release Date : 2024-03-08

The Role Of Non Coding Rnas In Gastrointestinal Cancers written by Kanjoormana Aryan Manu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-03-08 with Medical categories.


Gastrointestinal malignancies encompass a large number of tumor types, and collectively are responsible for a significant portion of new cancer cases annually. According to the IARC database, colorectal cancer alone is responsible for approximately 10% of new cases of cancer worldwide annually. There is significant heterogeneity across the various tumor types, with different pathways and factors involved in oncogenesis, as well as varying degrees of prognosis depending on the tumor type. Non-coding RNAs (ncRNAs) contribute to a significant portion of the human transcriptome, and of particular interest are the micro-RNAs (miRNAs), long ncRNAs (lncRNAs), and circular ncRNAs (circRNAs). With the advent of next-generation sequencing and new technologies such a minimally invasive biopsy techniques, there is a growing body of evidence elucidating the role of ncRNAs in the progression of various form of gastrointestinal cancers. Furthermore, in addition to their relevance to cancer progression, these ncRNAs have important potential as biomarkers and prognostic markers for various GI cancers.



Non Coding Rnas


Non Coding Rnas
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Author : Lütfi Tutar
language : en
Publisher: BoD – Books on Demand
Release Date : 2020-03-04

Non Coding Rnas written by Lütfi Tutar and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-04 with Medical categories.


Noncoding RNAs (ncRNAs) are an attractive research field in the RNA world. ncRNAs play important roles in regulating gene expression in animals, plants, and various human diseases. It is clear that current and further research on ncRNAs will change our knowledge of the nature of genome composition by editing previous dogmas. This book provides an overview of current knowledge on ncRNA research by dealing with miRNA and ncRNA-related human diseases, plant miRNA markers, and the roles of lncRNAs in cancer and epigenetics.