Roles Of Non Coding Rnas In Tumor Growth And Development
DOWNLOAD
Download Roles Of Non Coding Rnas In Tumor Growth And Development PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Roles Of Non Coding Rnas In Tumor Growth And Development book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Roles Of Non Coding Rnas In Tumor Growth And Development
DOWNLOAD
Author : Giovanni Blandino
language : en
Publisher: Frontiers Media SA
Release Date : 2023-01-05
Roles Of Non Coding Rnas In Tumor Growth And Development written by Giovanni Blandino and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-05 with Medical categories.
Long Non Coding Rnas In Cancer
DOWNLOAD
Author : Alfons Navarro
language : en
Publisher: Humana
Release Date : 2021-06-24
Long Non Coding Rnas In Cancer written by Alfons Navarro and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-24 with Medical categories.
This volume presents techniques needed for the study of long non-coding RNAs (lncRNAs) in cancer from their identification to functional characterization. Chapters guide readers through identification of lncRNA expression signatures in cancer tissue or liquid biopsies by RNAseq, single Cell RNAseq, Phospho RNAseq or Nanopore Sequencing techniques; validation of lncRNA signatures by Real time PCR, digital PCR or in situ hybridization; and functional analysis by siRNA or CRISPR based methods for lncRNA silencing or overexpression. Lipid based nanoparticles for delivery of siRNAs in vivo, lncRNA-protein interactions, viral lncRNAs and circRNAs are also treated in this volume. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and practical, Long Non-Coding RNAs in Cancer aims to provide a collection of laboratory protocols, bioinformatic pipelines, and review chapters to further research in this vital field.
The Role Of Ncrnas Non Coding Rnas In Regulating Tumor Immune Microenvironment
DOWNLOAD
Author : Yanyan Tang
language : en
Publisher: Frontiers Media SA
Release Date : 2022-09-14
The Role Of Ncrnas Non Coding Rnas In Regulating Tumor Immune Microenvironment written by Yanyan Tang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-14 with Science categories.
Pharmacological Properties Of Plant Derived Natural Products And Implications For Human Health
DOWNLOAD
Author : George E. Barreto
language : en
Publisher: Springer Nature
Release Date : 2021-04-16
Pharmacological Properties Of Plant Derived Natural Products And Implications For Human Health written by George E. Barreto and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-16 with Medical categories.
Medicinal plants and their derived products remain as an indispensable source of bioactive molecules that serve as either drug candidates or lead compounds for drug design and discovery. There are several advantages for plant-derived therapeutics including wide availability, diverse pharmacological actions and a generally good profile of safety and tolerability. Over the recent years, there have been numerous reports from clinical studies testifying to the efficacy and safety of medicinal plants and phytochemicals in ameliorating several human diseases. A plethora of basic studies has also unravelled molecular mechanisms underlying the health benefits of herbal medicines. Nevertheless, issues such as identification of bioactive ingredients, standardization of the products and drug interactions remain to be further studied. In this book, we aim to put together several chapters on the medicinal properties and pharmacological action of medicinal plants, plant species and phytochemicals. The goal is to present a comprehensive collection on most of the therapeutic aspects of plant-derived natural products and molecular mechanisms thereof.
Human And Oncoviral Noncoding Rnas As Modulators Of Cancer Aggressiveness And Disease Progression
DOWNLOAD
Author : Deilson Elgui De Oliveira
language : en
Publisher: Frontiers Media SA
Release Date : 2021-03-05
Human And Oncoviral Noncoding Rnas As Modulators Of Cancer Aggressiveness And Disease Progression written by Deilson Elgui De Oliveira and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-05 with Science categories.
Extracellular Vesicles
DOWNLOAD
Author :
language : en
Publisher: BoD – Books on Demand
Release Date : 2022-07-20
Extracellular Vesicles written by and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-07-20 with Science categories.
Extracellular vesicles (EVs) are nanoscale vesicles secreted by cells that mediate horizontal cargo transport from donor to recipient cell, thereby establishing cell-cell communication and signaling. This book provides critical information on the fundamentals of EVs, their roles in diseases like cancer, and their use in disease management. The chapters emphasize the emerging data confirming the role of EVs in the pathogenesis of diseases and discuss the scientific advances that have made it feasible to characterize and engineer EVs, leading to their use as tools in biomarker discovery and disease diagnosis, prognosis, therapeutic application, and theranostics. This volume is a valuable resource for basic biologists, translational scientists, and clinicians.
Non Coding Rnas And Cancer
DOWNLOAD
Author : Muller Fabbri
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-10-28
Non Coding Rnas And Cancer written by Muller Fabbri and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-28 with Medical categories.
The discovery of microRNAs and its role as gene expression regulators in human carcinogenesis represents one of the most important scientific achievements of the last decade. More recently, other non-coding RNAs have been discovered and its implications in cancer are emerging as well, suggesting a broader than anticipated involvement of the non-coding genome in cancer. Moreover, completely new and unexpected functions for microRNAs are being revealed, leading to the identification of new anticancer molecular targets. This book represents a comprehensive guide on non-coding RNAs and cancer, spanning from its role as cancer biomarkers, to providing the most useful bioinformatic tools, to presenting some of the most relevant discoveries, which indicates how these fascinating molecules act as fine orchestrators of cancer biology.
Non Coding Rnas In Breast Cancer Volume Ii
DOWNLOAD
Author : Wenwen Zhang
language : en
Publisher: Frontiers Media SA
Release Date : 2025-02-21
Non Coding Rnas In Breast Cancer Volume Ii written by Wenwen Zhang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-02-21 with Medical categories.
Breast cancer (BC) is the most common malignancy among females worldwide. Breast cancer is a highly heterogeneous malignant tumor which is constitutive of different subtypes according to the status of estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (Her-2), with diverse clinical performance, biological characteristics and prognosis. Despite early diagnosis and comprehensive treatment, especially the development of endocrine therapy, molecular targeted therapy and the emerging immunotherapies, the mortality of breast cancer has still remained relatively high. Therefore, identification of novel biomarkers for therapeutic targets and efficacy prediction of breast cancer is urgently required. The vast majority of the human genome is made up of non-coding RNA (ncRNA), apart from about 2% protein-coding genes. ncRNAs, including circular RNA (circRNA), circular RNAs (circRNAs), microRNAs (miRNAs), and long non-coding RNAs (lncRNAs), have been one of the hot spots in recent years. So far, a large number of ncRNAs have been recognized and found to be dysregulated in various types of cancer including breast cancer. Several ncRNAs have been reported to play critical roles in various biological processes of breast cancer, including cell proliferation, apoptosis, migration, invasion, angiogenesis, differentiation and drug resistance. Moreover, the potential of ncRNAs as diagnostic, prognostic biomarkers, and therapeutic targets has also been explored extensively in breast cancer. Accumulating studies indicating the significance of ncRNAs in the regulation of breast cancer development and drug resistance accelerated the investigation to explore the potential ncRNAs-based therapeutics in breast cancer patients. The main advantage of ncRNA based therapeutics is that it can target multiple coding or non-coding genes that regulate specific or redundant pathways involved in cancer development. However, therapeutics based on ncRNAs encounter some obstacles, such as problems associated with the delivery, potential off-target effects, and safety.
Microrna Signaling
DOWNLOAD
Author : Dragos Cretoiu
language : en
Publisher: Frontiers Media SA
Release Date : 2020-12-29
Microrna Signaling written by Dragos Cretoiu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-29 with Science categories.
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
The Role Of Non Coding Rnas In Gastrointestinal Cancers
DOWNLOAD
Author : Kanjoormana Aryan Manu
language : en
Publisher: Frontiers Media SA
Release Date : 2024-03-08
The Role Of Non Coding Rnas In Gastrointestinal Cancers written by Kanjoormana Aryan Manu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-03-08 with Medical categories.
Gastrointestinal malignancies encompass a large number of tumor types, and collectively are responsible for a significant portion of new cancer cases annually. According to the IARC database, colorectal cancer alone is responsible for approximately 10% of new cases of cancer worldwide annually. There is significant heterogeneity across the various tumor types, with different pathways and factors involved in oncogenesis, as well as varying degrees of prognosis depending on the tumor type. Non-coding RNAs (ncRNAs) contribute to a significant portion of the human transcriptome, and of particular interest are the micro-RNAs (miRNAs), long ncRNAs (lncRNAs), and circular ncRNAs (circRNAs). With the advent of next-generation sequencing and new technologies such a minimally invasive biopsy techniques, there is a growing body of evidence elucidating the role of ncRNAs in the progression of various form of gastrointestinal cancers. Furthermore, in addition to their relevance to cancer progression, these ncRNAs have important potential as biomarkers and prognostic markers for various GI cancers.